This is a Validated Antibody Database (VAD) review about mouse GCN2, based on 7 published articles (read how Labome selects the articles), using GCN2 antibody in all methods. It is aimed to help Labome visitors find the most suited GCN2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
GCN2 synonym: 2610011M03; GCN2; MGCN2; eIF-2-alpha kinase GCN2; GCN2 eIF2alpha kinase; GCN2-like protein

Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s4f
Cell Signaling Technology GCN2 antibody (Cell Signaling Technology, 3302) was used in western blot on mouse samples at 1:1000 (fig s4f). Nat Commun (2019) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:20; loading ...; fig 2
  • western blot; mouse; 1:100; loading ...; fig 1b
Cell Signaling Technology GCN2 antibody (Cell Signaling, 3302) was used in immunohistochemistry - paraffin section on mouse samples at 1:20 (fig 2) and in western blot on mouse samples at 1:100 (fig 1b). Mol Reprod Dev (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 3c
Cell Signaling Technology GCN2 antibody (Cell Signaling Technology, 3302) was used in western blot on human samples (fig 3c). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology GCN2 antibody (Cell Signaling, 3302) was used in western blot on human samples (fig 2). Autophagy (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 3
In order to determine regulation of global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha by the small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives, Cell Signaling Technology GCN2 antibody (Cell signaling, 3302) was used in western blot on rat samples (fig 3). Cell Stress Chaperones (2016) ncbi
rabbit polyclonal
  • western blot; human; fig s7
Cell Signaling Technology GCN2 antibody (Cell Signaling, 3302) was used in western blot on human samples (fig s7). Autophagy (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
  • western blot; mouse; fig 4
Cell Signaling Technology GCN2 antibody (cell signaling, 3302) was used in western blot on human samples (fig 4) and in western blot on mouse samples (fig 4). Mol Cell Biol (2015) ncbi
Articles Reviewed
  1. Cao Y, Trillo Tinoco J, Sierra R, Anadon C, Dai W, Mohamed E, et al. ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression. Nat Commun. 2019;10:1280 pubmed publisher
  2. Yoon J, Park K, Hwang D, Rhee K. Importance of eIF2α phosphorylation as a protective mechanism against heat stress in mouse male germ cells. Mol Reprod Dev. 2017;84:265-274 pubmed publisher
  3. Chaveroux C, Sarcinelli C, Barbet V, Belfeki S, Barthelaix A, Ferraro Peyret C, et al. Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway. Sci Rep. 2016;6:27278 pubmed publisher
  4. Bretin A, Carrière J, Dalmasso G, Bergougnoux A, B chir W, Maurin A, et al. Activation of the EIF2AK4-EIF2A/eIF2?-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasive Escherichia coli infection. Autophagy. 2016;12:770-83 pubmed publisher
  5. Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
  6. Artero Castro A, Perez Alea M, Feliciano A, Leal J, Genestar M, Castellvi J, et al. Disruption of the ribosomal P complex leads to stress-induced autophagy. Autophagy. 2015;11:1499-519 pubmed publisher
  7. So J, Cho S, Min S, Kimball S, Lee A. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis. Mol Cell Biol. 2015;35:2761-70 pubmed publisher