This is a Validated Antibody Database (VAD) review about mouse Fto, based on 7 published articles (read how Labome selects the articles), using Fto antibody in all methods. It is aimed to help Labome visitors find the most suited Fto antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Fto synonym: AW743446; mKIAA1752

Knockout validation
Adipogen
rat monoclonal (FT342-1)
  • western blot knockout validation; mouse; fig 1
In order to elucidate the relationship among FTO, IRX3 and fat metabolism, Adipogen Fto antibody (AdipoGen, AG-20A-0088) was used in western blot knockout validation on mouse samples (fig 1). Sci Rep (2015) ncbi
Abcam
mouse monoclonal (5-2H10)
  • western blot; mouse; loading ...; fig 1e
Abcam Fto antibody (Abcam, ab92821) was used in western blot on mouse samples (fig 1e). Cell Death Dis (2021) ncbi
mouse monoclonal (5-2H10)
  • proximity ligation assay; human; 1:200; fig 8j
  • immunohistochemistry; human; loading ...; fig 4a
Abcam Fto antibody (Abcam, ab92821) was used in proximity ligation assay on human samples at 1:200 (fig 8j) and in immunohistochemistry on human samples (fig 4a). Nat Commun (2021) ncbi
mouse monoclonal (5-2H10)
  • western blot; mouse; loading ...; fig s1a
Abcam Fto antibody (Abcam, ab92821) was used in western blot on mouse samples (fig s1a). Nat Chem Biol (2019) ncbi
Abnova
domestic goat polyclonal
  • western blot; mouse; fig 1
Abnova Fto antibody (Abnova, PAB11419) was used in western blot on mouse samples (fig 1). Sci Rep (2016) ncbi
Phosphosolutions
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1h
Phosphosolutions Fto antibody (Phosphosolutions, 597-FTO) was used in immunocytochemistry on mouse samples at 1:500 (fig 1h). Nucleic Acids Res (2018) ncbi
  • immunocytochemistry; mouse; 1:600; fig e1
  • western blot; mouse; 1:1000; fig 1
Phosphosolutions Fto antibody (Phosphosolutions, 597-Fto) was used in immunocytochemistry on mouse samples at 1:600 (fig e1) and in western blot on mouse samples at 1:1000 (fig 1). Nature (2015) ncbi
Adipogen
rat monoclonal (FT342-1)
  • western blot knockout validation; mouse; fig 1
In order to elucidate the relationship among FTO, IRX3 and fat metabolism, Adipogen Fto antibody (AdipoGen, AG-20A-0088) was used in western blot knockout validation on mouse samples (fig 1). Sci Rep (2015) ncbi
Articles Reviewed
  1. Lü Z, Liu H, Song N, Liang Y, Zhu J, Chen J, et al. METTL14 aggravates podocyte injury and glomerulopathy progression through N6-methyladenosine-dependent downregulating of Sirt1. Cell Death Dis. 2021;12:881 pubmed publisher
  2. Cui Y, Yang S, Wei J, Shea C, Zhong W, Wang F, et al. Autophagy of the m6A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis. Nat Commun. 2021;12:2183 pubmed publisher
  3. Mauer J, Sindelar M, Despic V, Guez T, Hawley B, Vasseur J, et al. FTO controls reversible m6Am RNA methylation during snRNA biogenesis. Nat Chem Biol. 2019;15:340-347 pubmed publisher
  4. Yu J, Chen M, Huang H, Zhu J, Song H, Zhu J, et al. Dynamic m6A modification regulates local translation of mRNA in axons. Nucleic Acids Res. 2018;46:1412-1423 pubmed publisher
  5. Wang C, Shie S, Tsai M, Yang C, Hung K, Wang C, et al. FTO modulates fibrogenic responses in obstructive nephropathy. Sci Rep. 2016;6:18874 pubmed publisher
  6. Zhou J, Wan J, Gao X, Zhang X, Jaffrey S, Qian S. Dynamic m(6)A mRNA methylation directs translational control of heat shock response. Nature. 2015;526:591-4 pubmed publisher
  7. Ronkainen J, Huusko T, Soininen R, Mondini E, Cinti F, Mäkelä K, et al. Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue. Sci Rep. 2015;5:9233 pubmed publisher