This is a Validated Antibody Database (VAD) review about mouse Frs2, based on 12 published articles (read how Labome selects the articles), using Frs2 antibody in all methods. It is aimed to help Labome visitors find the most suited Frs2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Frs2 synonym: 4732458E18; C330018A15Rik; Frs2alpha; SNT1; fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR-signaling adaptor SNT; FRS2-alpha; SNT-1; suc1-associated neurotrophic factor target 1

R&D Systems
mouse monoclonal (462910)
  • western blot; human; loading ...; fig 3h
R&D Systems Frs2 antibody (R&D Systems, MAB4069) was used in western blot on human samples (fig 3h). Genes Cancer (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200
R&D Systems Frs2 antibody (R&D systems, AF5126) was used in immunocytochemistry on mouse samples at 1:200. Mol Cell Endocrinol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-5)
  • western blot; human
Santa Cruz Biotechnology Frs2 antibody (Santa Cruz Biotechnology, sc-17841) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000; fig s3f
Cell Signaling Technology Frs2 antibody (Cell Signaling, 3861) was used in western blot on human samples at 1:1000 (fig s3f). Nature (2018) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:30; loading ...; fig 1
Cell Signaling Technology Frs2 antibody (cell signalling, 3861) was used in immunocytochemistry on human samples at 1:30 (fig 1). Oncotarget (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 2a
Cell Signaling Technology Frs2 antibody (Cell Signaling, 3861) was used in western blot on human samples (fig 2a). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 9e
Cell Signaling Technology Frs2 antibody (Cell Signaling Tech, 3861) was used in western blot on mouse samples at 1:1000 (fig 9e). PLoS ONE (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
Cell Signaling Technology Frs2 antibody (Cell Signaling Technology, 3864) was used in western blot on mouse samples (fig 4). Mol Biol Cell (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Frs2 antibody (Cell Signaling, 3861S) was used in western blot on human samples (fig 4). Proc Natl Acad Sci U S A (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Frs2 antibody (Cell Signaling, 3864) was used in western blot on human samples (fig 4). Proc Natl Acad Sci U S A (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Frs2 antibody (Cell Signaling, 3864) was used in western blot on human samples . J Thyroid Res (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Frs2 antibody (Cell Signaling Technology, 3861) was used in western blot on human samples . Biochim Biophys Acta (2014) ncbi
rabbit polyclonal
  • western blot; human
In order to study mechanism of resistance to the FGFR inhibitor BGJ398 and the FGFR inhibitor ponatinib, Cell Signaling Technology Frs2 antibody (cell signaling, 3861S) was used in western blot on human samples . Oncogene (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:100
Cell Signaling Technology Frs2 antibody (Cell Signaling, 3861) was used in western blot on mouse samples at 1:100. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher
  2. Feng S, Shao L, Castro P, Coleman I, Nelson P, Smith P, et al. Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors. Oncotarget. 2017;8:6179-6192 pubmed publisher
  3. Piasecka D, Kitowska K, Czaplinska D, Mieczkowski K, Mieszkowska M, Turczyk L, et al. Fibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells. Oncotarget. 2016;7:86011-86025 pubmed publisher
  4. Elzi D, Song M, Blackman B, Weintraub S, Lopez Terrada D, Chen Y, et al. FGF19 functions as autocrine growth factor for hepatoblastoma. Genes Cancer. 2016;7:125-35 pubmed publisher
  5. Chen Q, Arai D, Kawakami K, Sawada T, Jing X, Miyajima M, et al. EphA4 Regulates the Balance between Self-Renewal and Differentiation of Radial Glial Cells and Intermediate Neuronal Precursors in Cooperation with FGF Signaling. PLoS ONE. 2015;10:e0126942 pubmed publisher
  6. Boswell B, Musil L. Synergistic interaction between the fibroblast growth factor and bone morphogenetic protein signaling pathways in lens cells. Mol Biol Cell. 2015;26:2561-72 pubmed publisher
  7. Chung D, Gao F, Jegga A, Das S. Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a. Mol Cell Endocrinol. 2015;400:48-60 pubmed publisher
  8. Tan L, Wang J, Tanizaki J, Huang Z, Aref A, Rusan M, et al. Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors. Proc Natl Acad Sci U S A. 2014;111:E4869-77 pubmed publisher
  9. Tohyama O, Matsui J, Kodama K, Hata Sugi N, Kimura T, Okamoto K, et al. Antitumor activity of lenvatinib (e7080): an angiogenesis inhibitor that targets multiple receptor tyrosine kinases in preclinical human thyroid cancer models. J Thyroid Res. 2014;2014:638747 pubmed publisher
  10. Czaplinska D, Turczyk L, Grudowska A, Mieszkowska M, Lipinska A, Skladanowski A, et al. Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration. Biochim Biophys Acta. 2014;1843:2461-70 pubmed publisher
  11. Wang J, Mikse O, Liao R, Li Y, Tan L, Jänne P, et al. Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells. Oncogene. 2015;34:2167-77 pubmed publisher
  12. Lee S, Griep A. Loss of Dlg-1 in the mouse lens impairs fibroblast growth factor receptor signaling. PLoS ONE. 2014;9:e97470 pubmed publisher