This is a Validated Antibody Database (VAD) review about mouse Fen1, based on 10 published articles (read how Labome selects the articles), using Fen1 antibody in all methods. It is aimed to help Labome visitors find the most suited Fen1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Fen1 synonym: AW538437; FEN-1; flap endonuclease 1; fen1

GeneTex
mouse monoclonal (4E7)
  • immunohistochemistry - paraffin section; human; loading ...; fig 1b
  • western blot; human; loading ...; fig 2a
In order to show that flap endonuclease 1 is critical for the rapid proliferation of lung cancer cells, GeneTex Fen1 antibody (Gentex, 70185) was used in immunohistochemistry - paraffin section on human samples (fig 1b) and in western blot on human samples (fig 2a). Mol Oncol (2017) ncbi
mouse monoclonal (4E7)
  • immunoprecipitation; human; loading ...; fig 5a
  • western blot; human; loading ...; fig 5a
GeneTex Fen1 antibody (GeneTex, GTX70185) was used in immunoprecipitation on human samples (fig 5a) and in western blot on human samples (fig 5a). EMBO J (2015) ncbi
mouse monoclonal (4E7)
  • western blot; human
GeneTex Fen1 antibody (Genetex, GTX70185) was used in western blot on human samples . Mol Cell Biol (2008) ncbi
mouse monoclonal (4E7)
  • western blot; human
GeneTex Fen1 antibody (Genetex, GTX70185) was used in western blot on human samples . Mol Cell Biol (2008) ncbi
mouse monoclonal (4E7)
  • western blot; human
GeneTex Fen1 antibody (Genetex Company, GTX70185) was used in western blot on human samples . J Mol Biol (2008) ncbi
Abcam
rabbit monoclonal (EPR4460(2))
  • western blot; human; 1:5000; loading ...; fig 5n
Abcam Fen1 antibody (Abcam, AB109132) was used in western blot on human samples at 1:5000 (fig 5n). Aging (Albany NY) (2018) ncbi
Bethyl
rabbit polyclonal
  • western blot; human; fig 2
Bethyl Fen1 antibody (Bethyl, A300-255A) was used in western blot on human samples (fig 2). J Biol Chem (2015) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig 1
  • western blot; human; fig 1
Bethyl Fen1 antibody (Bethyl Lab, A300-255A) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Biochem J (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; loading ...; fig 7b
Cell Signaling Technology Fen1 antibody (Cell Signaling, 2746) was used in western blot on human samples (fig 7b). Oncol Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6c
In order to study quinacrine-induced apoptosis, Cell Signaling Technology Fen1 antibody (Cell Signaling, 2746) was used in western blot on human samples (fig 6c). Biochem Pharmacol (2016) ncbi
Articles Reviewed
  1. Ma S, Yang D, Liu Y, Wang Y, Lin T, Li Y, et al. LncRNA BANCR promotes tumorigenesis and enhances adriamycin resistance in colorectal cancer. Aging (Albany NY). 2018;10:2062-2078 pubmed publisher
  2. He L, Luo L, Zhu H, Yang H, Zhang Y, Wu H, et al. FEN1 promotes tumor progression and confers cisplatin resistance in non-small-cell lung cancer. Mol Oncol. 2017;11:640-654 pubmed publisher
  3. Sumiyoshi H, Matsushita A, Nakamura Y, Matsuda Y, Ishiwata T, Naito Z, et al. Suppression of STAT5b in pancreatic cancer cells leads to attenuated gemcitabine chemoresistance, adhesion and invasion. Oncol Rep. 2016;35:3216-26 pubmed publisher
  4. Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  5. Teasley D, Parajuli S, Nguyen M, Moore H, Alspach E, Lock Y, et al. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand. J Biol Chem. 2015;290:15133-45 pubmed publisher
  6. Liu S, Lu G, Ali S, Liu W, Zheng L, Dai H, et al. Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex. EMBO J. 2015;34:1829-43 pubmed publisher
  7. Sami F, Lu X, Parvathaneni S, Roy R, Gary R, Sharma S. RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin. Biochem J. 2015;468:227-44 pubmed publisher
  8. Liu P, Qian L, Sung J, de Souza Pinto N, Zheng L, Bogenhagen D, et al. Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria. Mol Cell Biol. 2008;28:4975-87 pubmed publisher
  9. Guo Z, Qian L, Liu R, Dai H, Zhou M, Zheng L, et al. Nucleolar localization and dynamic roles of flap endonuclease 1 in ribosomal DNA replication and damage repair. Mol Cell Biol. 2008;28:4310-9 pubmed publisher
  10. Guo Z, Chavez V, Singh P, Finger L, Hang H, Hegde M, et al. Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways. J Mol Biol. 2008;377:679-90 pubmed publisher