This is a Validated Antibody Database (VAD) review about mouse Fancd2, based on 25 published articles (read how Labome selects the articles), using Fancd2 antibody in all methods. It is aimed to help Labome visitors find the most suited Fancd2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Fancd2 synonym: 2410150O07Rik; AU015151; BB137857; FA-D2; FA4; FACD; FAD; FANCD

Novus Biologicals
domestic rabbit polyclonal (OTI2B3)
  • immunocytochemistry; mouse; 1:800; loading ...; fig 4i
Novus Biologicals Fancd2 antibody (Novus, NB100-182) was used in immunocytochemistry on mouse samples at 1:800 (fig 4i). elife (2020) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:1000; loading ...; fig 4e
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples at 1:1000 (fig 4e). EMBO Mol Med (2019) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:1000; loading ...; fig 7c
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples at 1:1000 (fig 7c). Nat Commun (2018) ncbi
mouse monoclonal (FI-17)
  • immunocytochemistry; human; 1:1000; loading ...; fig 4c
Novus Biologicals Fancd2 antibody (Novus Biologicals, nb100-316) was used in immunocytochemistry on human samples at 1:1000 (fig 4c). Nucleic Acids Res (2018) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:2000; loading ...; fig 4d
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples at 1:2000 (fig 4d). Cell Rep (2018) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry; human; fig 4d
Novus Biologicals Fancd2 antibody (Novus, NB100-182) was used in immunohistochemistry on human samples (fig 4d). Mol Cell (2018) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig 4f
In order to explore the role of Fancd2 in normal development and tumorigenesis, Novus Biologicals Fancd2 antibody (novusbio, NB100-182) was used in western blot on mouse samples (fig 4f). Sci Rep (2017) ncbi
domestic rabbit polyclonal (OTI2B3)
  • chromatin immunoprecipitation; human; loading ...; fig 6a
  • immunohistochemistry; human; fig 2a
In order to determine that HPV activates the Fanconi anemia pathway, leading to the accumulation of a key regulatory protein, FANCD2, in large nuclear foci, Novus Biologicals Fancd2 antibody (Novus, NB100-182) was used in chromatin immunoprecipitation on human samples (fig 6a) and in immunohistochemistry on human samples (fig 2a). MBio (2017) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunocytochemistry; human; loading ...; fig 2A
  • western blot; human; loading ...; fig 2C
In order to investigate the role of the PTEN phosphatase in DNA interstrand crosslink repair, Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used in immunocytochemistry on human samples (fig 2A) and in western blot on human samples (fig 2C). Sci Rep (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry; human; loading ...; fig 5d
Novus Biologicals Fancd2 antibody (Novus, NB100-182) was used in immunohistochemistry on human samples (fig 5d). Sci Rep (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry - paraffin section; mouse; 1:100; tbl 1
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (tbl 1). PLoS ONE (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; fig 1
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used in western blot on human samples (fig 1). Nat Struct Mol Biol (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunocytochemistry; human; loading ...; fig 4c
Novus Biologicals Fancd2 antibody (Novus, NB100-182) was used in immunocytochemistry on human samples (fig 4c). Cell Rep (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used . Cancer Res (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
In order to show that FANCD2 is needed for genome stability maintenance in response to high-linear energy transfer radiation, Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used . Cell Cycle (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used . DNA Repair (Amst) (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Fancd2 antibody (Novus Biologicals, NB100-182) was used . DNA Repair (Amst) (2015) ncbi
Abcam
domestic rabbit monoclonal (EPR2302)
  • ChIP-Seq; mouse; loading ...; fig s3a
  • western blot; mouse; 1:2000; loading ...; fig s1a
  • western blot; human; 1:2000; loading ...; fig s1a
Abcam Fancd2 antibody (Abcam, ab221932) was used in ChIP-Seq on mouse samples (fig s3a), in western blot on mouse samples at 1:2000 (fig s1a) and in western blot on human samples at 1:2000 (fig s1a). Science (2019) ncbi
domestic rabbit monoclonal (EPR2302)
  • western blot; human; fig 7e
Abcam Fancd2 antibody (Abcam, ab108928) was used in western blot on human samples (fig 7e). Cell (2018) ncbi
domestic rabbit monoclonal (EPR2302)
  • western blot; human; loading ...; fig 1a
In order to determine that HPV activates the Fanconi anemia pathway, leading to the accumulation of a key regulatory protein, FANCD2, in large nuclear foci, Abcam Fancd2 antibody (Abcam, ab108928) was used in western blot on human samples (fig 1a). MBio (2017) ncbi
domestic rabbit monoclonal (EPR2302)
  • immunocytochemistry; mouse; 1:50; loading ...; fig 6e
Abcam Fancd2 antibody (Abcam, ab108928) was used in immunocytochemistry on mouse samples at 1:50 (fig 6e). Nat Commun (2017) ncbi
domestic rabbit monoclonal (EPR2302)
  • western blot; mouse; 1:500; loading ...; fig 1d
Abcam Fancd2 antibody (Abcam, ab108928) was used in western blot on mouse samples at 1:500 (fig 1d). Nat Commun (2016) ncbi
domestic rabbit monoclonal (EPR2302)
  • western blot; mouse; 1:200; fig s6
In order to study resolution of DNA interstrand cross-links by cooperation of BRCA2 and MERIT40, Abcam Fancd2 antibody (Abcam, ab108928) was used in western blot on mouse samples at 1:200 (fig s6). Genes Dev (2015) ncbi
domestic rabbit monoclonal (EPR2302)
  • western blot; human; fig 4
In order to report the effects of new temozolomide analogues on glioblastoma multiforme, Abcam Fancd2 antibody (Epitomics, 2986-1) was used in western blot on human samples (fig 4). Mol Cancer Ther (2015) ncbi
domestic rabbit monoclonal (EPR2302)
  • western blot; human; 1:1000
Abcam Fancd2 antibody (Abcam, EPR2302) was used in western blot on human samples at 1:1000. DNA Repair (Amst) (2014) ncbi
domestic rabbit monoclonal (EPR2302)
  • immunocytochemistry; mouse
  • western blot; mouse
Abcam Fancd2 antibody (Abcam, ab108928) was used in immunocytochemistry on mouse samples and in western blot on mouse samples . Nucleic Acids Res (2013) ncbi
Articles Reviewed
  1. Atkins A, Xu M, Li M, Rogers N, Pryzhkova M, Jordan P. SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. elife. 2020;9: pubmed publisher
  2. Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;11:e9982 pubmed publisher
  3. Wienert B, Wyman S, Richardson C, Yeh C, Akçakaya P, Porritt M, et al. Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq. Science. 2019;364:286-289 pubmed publisher
  4. Balcerek J, Jiang J, Li Y, Jiang Q, Holdreith N, Singh B, et al. Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia. Nat Commun. 2018;9:3915 pubmed publisher
  5. Slyskova J, Sabatella M, Ribeiro Silva C, Stok C, Theil A, Vermeulen W, et al. Base and nucleotide excision repair facilitate resolution of platinum drugs-induced transcription blockage. Nucleic Acids Res. 2018;46:9537-9549 pubmed publisher
  6. Tay L, Krishnan V, Sankar H, Chong Y, Chuang L, Tan T, et al. RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. Cell Rep. 2018;24:1747-1755 pubmed publisher
  7. Hoshii T, Cifani P, Feng Z, Huang C, Koche R, Chen C, et al. A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response. Cell. 2018;172:1007-1021.e17 pubmed publisher
  8. Kim J, Sturgill D, Sebastian R, Khurana S, Tran A, Edwards G, et al. Replication Stress Shapes a Protective Chromatin Environment across Fragile Genomic Regions. Mol Cell. 2018;69:36-47.e7 pubmed publisher
  9. Zhang T, Du W, Wilson A, Namekawa S, Andreassen P, Meetei A, et al. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Sci Rep. 2017;7:45626 pubmed publisher
  10. Spriggs C, Laimins L. FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication. MBio. 2017;8: pubmed publisher
  11. Kang Y, Balter B, Csizmadia E, Haas B, Sharma H, Bronson R, et al. Contribution of classical end-joining to PTEN inactivation in p53-mediated glioblastoma formation and drug-resistant survival. Nat Commun. 2017;8:14013 pubmed publisher
  12. Vuono E, Mukherjee A, Vierra D, Adroved M, Hodson C, Deans A, et al. The PTEN phosphatase functions cooperatively with the Fanconi anemia proteins in DNA crosslink repair. Sci Rep. 2016;6:36439 pubmed publisher
  13. Bezine E, Malaisé Y, Loeuillet A, Chevalier M, Boutet Robinet E, Salles B, et al. Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms. Sci Rep. 2016;6:36022 pubmed publisher
  14. Fu C, Begum K, Jordan P, He Y, Overbeek P. Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice. PLoS ONE. 2016;11:e0159800 pubmed publisher
  15. Michl J, Zimmer J, Buffa F, McDermott U, Tarsounas M. FANCD2 limits replication stress and genome instability in cells lacking BRCA2. Nat Struct Mol Biol. 2016;23:755-757 pubmed publisher
  16. Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed publisher
  17. Jaber S, Toufektchan E, Lejour V, Bardot B, Toledo F. p53 downregulates the Fanconi anaemia DNA repair pathway. Nat Commun. 2016;7:11091 pubmed publisher
  18. Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, et al. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes Dev. 2015;29:1955-68 pubmed publisher
  19. Stoepker C, Ameziane N, van der Lelij P, Kooi I, Oostra A, Rooimans M, et al. Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer. Cancer Res. 2015;75:3543-53 pubmed publisher
  20. Zhu J, Su F, Mukherjee S, Mori E, Hu B, Asaithamby A. FANCD2 influences replication fork processes and genome stability in response to clustered DSBs. Cell Cycle. 2015;14:1809-22 pubmed publisher
  21. Stoepker C, Faramarz A, Rooimans M, van Mil S, Balk J, Velleuer E, et al. DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity. DNA Repair (Amst). 2015;26:54-64 pubmed publisher
  22. Bursomanno S, Beli P, Khan A, Minocherhomji S, Wagner S, Bekker Jensen S, et al. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. DNA Repair (Amst). 2015;25:84-96 pubmed publisher
  23. Ramirez Y, Mladek A, Phillips R, Gynther M, Rautio J, Ross A, et al. Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth. Mol Cancer Ther. 2015;14:111-9 pubmed publisher
  24. Schmidt L, Wiedner M, Velimezi G, Prochazkova J, Owusu M, Bauer S, et al. ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress. DNA Repair (Amst). 2014;24:122-130 pubmed publisher
  25. Luebben S, Kawabata T, Akre M, Lee W, Johnson C, O Sullivan M, et al. Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Res. 2013;41:10283-97 pubmed publisher