mouse Ezh2 antibody | antibody review based on formal publications

This is a Validated Antibody Database (VAD) review about mouse Ezh2, based on 130 published articles (read how Labome selects the articles), using Ezh2 antibody in all methods. It is aimed to help Labome visitors find the most suited Ezh2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.

Ezh2 synonym: Enx-1; Enx1h; KMT6; mKIAA4065

Knockout validation

Cell Signaling Technology domestic rabbit monoclonal (D2C9) 5246	western blot knockout validation; human; loading ...; fig 4e	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot knockout validation on human samples (fig 4e). Nat Commun (2020) ncbi
Cell Signaling Technology domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry knockout validation; mouse; loading ...; fig 2a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in immunohistochemistry knockout validation on mouse samples (fig 2a). J Bone Miner Res (2020) ncbi
Cell Signaling Technology domestic rabbit monoclonal (D2C9) 5246	western blot knockout validation; mouse; fig 1c	Cell Signaling Technology Ezh2 antibody (CST, 5246) was used in western blot knockout validation on mouse samples (fig 1c). J Exp Med (2016) ncbi
Cell Signaling Technology mouse monoclonal (AC22) 3147	western blot knockout validation; human; fig 1	Cell Signaling Technology Ezh2 antibody (Cell Signaling Tech, 3147) was used in western blot knockout validation on human samples (fig 1). Biol Proced Online (2015) ncbi

Active Motif

mouse monoclonal (AC22) 39875	chromatin immunoprecipitation; human; loading ...; fig s10b western blot; human; 1:10,000; fig 1b	Active Motif Ezh2 antibody (Active Motif, 39875) was used in chromatin immunoprecipitation on human samples (fig s10b) and in western blot on human samples at 1:10,000 (fig 1b). Nat Commun (2021) ncbi
mouse monoclonal (AC22) 39875	western blot; mouse; loading ...; fig 4e	Active Motif Ezh2 antibody (Active Motif, AC22) was used in western blot on mouse samples (fig 4e). Nat Commun (2018) ncbi
mouse monoclonal (AC22) 39875	RNA immunoprecipitation; human; fig 6 chromatin immunoprecipitation; human; fig 6	Active Motif Ezh2 antibody (Active Motif, 39875) was used in RNA immunoprecipitation on human samples (fig 6) and in chromatin immunoprecipitation on human samples (fig 6). Nat Immunol (2015) ncbi
mouse monoclonal (AC22) 39875	ChIP-Seq; human chromatin immunoprecipitation; human	Active Motif Ezh2 antibody (Active Motif, 39875) was used in ChIP-Seq on human samples and in chromatin immunoprecipitation on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (AC22) 39875	chromatin immunoprecipitation; mouse	Active Motif Ezh2 antibody (Active Motif, 39875) was used in chromatin immunoprecipitation on mouse samples . J Immunol (2013) ncbi
mouse monoclonal (AC22) 39875	chromatin immunoprecipitation; human	Active Motif Ezh2 antibody (Active Motif, 39875) was used in chromatin immunoprecipitation on human samples . PLoS ONE (2013) ncbi
mouse monoclonal (AC22) 39875	immunoprecipitation; human; 5 ul	Active Motif Ezh2 antibody (Active Motif, 39875) was used in immunoprecipitation on human samples at 5 ul. PLoS Pathog (2013) ncbi
mouse monoclonal (AC22) 39875	western blot; human	In order to study the mechanism by which SFMBT1 modulates epigenetic silencing and mitogenic gene expression, Active Motif Ezh2 antibody (Active Motif, 39875) was used in western blot on human samples . J Biol Chem (2013) ncbi
mouse monoclonal (AC22) 39875	chromatin immunoprecipitation; human western blot; human	Active Motif Ezh2 antibody (Active Motif, 39875) was used in chromatin immunoprecipitation on human samples and in western blot on human samples . J Virol (2012) ncbi

Invitrogen

mouse monoclonal (H.547.3) MA5-15101	immunocytochemistry; mouse; 1:200; fig 4b	Invitrogen Ezh2 antibody (Invitrogen, MA5?\15101) was used in immunocytochemistry on mouse samples at 1:200 (fig 4b). J Am Heart Assoc (2021) ncbi
domestic rabbit polyclonal PA5-105660	western blot; human; fig 5a	Invitrogen Ezh2 antibody (Invitrogen, PA5-105660) was used in western blot on human samples (fig 5a). Proc Natl Acad Sci U S A (2021) ncbi
mouse monoclonal (AC22) 14-9867-80 14-9867-82	chromatin immunoprecipitation; human; loading ...; fig 5e	Invitrogen Ezh2 antibody (Thermo, AC22) was used in chromatin immunoprecipitation on human samples (fig 5e). Nat Commun (2018) ncbi
mouse monoclonal (H.547.3) MA5-15101	immunocytochemistry; human; fig 4e	Invitrogen Ezh2 antibody (Thermo Fisher, MA5-15101) was used in immunocytochemistry on human samples (fig 4e). J Clin Invest (2017) ncbi
domestic rabbit polyclonal 36-6300	immunohistochemistry; human; 1:125; loading ...; fig 7d western blot; human; 1:250; loading ...; fig 4b	In order to propose that miR-101- mediated UHRF1 pathways are altered by sunitinib treatment, Invitrogen Ezh2 antibody (Life Technologies, 36-6300) was used in immunohistochemistry on human samples at 1:125 (fig 7d) and in western blot on human samples at 1:250 (fig 4b). Oncotarget (2016) ncbi
mouse monoclonal (H.547.3) MA5-15101	immunoprecipitation; human; fig 1e western blot; human; fig 1a	In order to test if lncRNA SRA interacts with TrxG or PRC2, Invitrogen Ezh2 antibody (Thermo Scientific, MA5-15101) was used in immunoprecipitation on human samples (fig 1e) and in western blot on human samples (fig 1a). PLoS Genet (2015) ncbi
domestic rabbit polyclonal 36-6300		In order to investigate the therapeutic potential of ribavirin as a cancer drug, Invitrogen Ezh2 antibody (Invitrogen, 36-6300) was used . Oncol Rep (2015) ncbi

Abcam

domestic rabbit polyclonal ab186006	western blot; human; 1:1000; loading ...; fig 5b	Abcam Ezh2 antibody (Abcam, ab186006) was used in western blot on human samples at 1:1000 (fig 5b). Int J Oncol (2021) ncbi
domestic rabbit polyclonal ab186006	western blot; mouse; 1:1000; loading ...; fig 7c	Abcam Ezh2 antibody (Abcam, ab186006) was used in western blot on mouse samples at 1:1000 (fig 7c). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal ab186006	western blot; human; loading ...; fig 1e	Abcam Ezh2 antibody (Abcam, ab186006) was used in western blot on human samples (fig 1e). Aging (Albany NY) (2021) ncbi
domestic rabbit polyclonal ab186006	immunohistochemistry; human; loading ...; fig 1c western blot; human; loading ...; fig 2g	Abcam Ezh2 antibody (Abcam, ab186006) was used in immunohistochemistry on human samples (fig 1c) and in western blot on human samples (fig 2g). Technol Cancer Res Treat (2021) ncbi
domestic rabbit monoclonal (EPR9307(2)) ab191080	western blot; human; loading ...; fig 3c, 3d	Abcam Ezh2 antibody (Abcam, ab191080) was used in western blot on human samples (fig 3c, 3d). Mol Cancer (2019) ncbi

Santa Cruz Biotechnology

mouse monoclonal (D-8) sc-137255	western blot; mouse; loading ...; fig s4a	Santa Cruz Biotechnology Ezh2 antibody (Santa, sc-137255) was used in western blot on mouse samples (fig s4a). Sci Rep (2018) ncbi
mouse monoclonal (C-1) sc-166609	western blot; human; 1:500; fig 6	Santa Cruz Biotechnology Ezh2 antibody (Santa Cruz, sc-166609) was used in western blot on human samples at 1:500 (fig 6). Oncotarget (2015) ncbi

Cell Signaling Technology

domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 2a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig 2a). iScience (2022) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 2b, 4e	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig 2b, 4e). Clin Transl Med (2022) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; mouse; 1:200; loading ...; fig 5k western blot; mouse; 1:2000; fig 5o	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246s) was used in immunohistochemistry on mouse samples at 1:200 (fig 5k) and in western blot on mouse samples at 1:2000 (fig 5o). elife (2022) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; 1:1000; loading ...; fig s10b	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246S) was used in western blot on mouse samples at 1:1000 (fig s10b). Nat Commun (2022) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; loading ...; fig s1a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on mouse samples (fig s1a). Adv Sci (Weinh) (2021) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; mouse; 1:200	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246S) was used in immunohistochemistry on mouse samples at 1:200. Nat Cancer (2021) ncbi
domestic rabbit monoclonal (D2C9) 5246		Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246S) was used . Sci Adv (2021) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 6d	Cell Signaling Technology Ezh2 antibody (cell signaling technology, 5246) was used in western blot on human samples (fig 6d). Front Oncol (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 1h, 4f	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246S) was used in western blot on human samples (fig 1h, 4f). Proc Natl Acad Sci U S A (2021) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; human; fig 6a western blot; human; loading ...; fig 5a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in immunohistochemistry on human samples (fig 6a) and in western blot on human samples (fig 5a). Theranostics (2021) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot knockout validation; human; loading ...; fig 4e	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot knockout validation on human samples (fig 4e). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; mouse; loading ...; fig 5f western blot; human; loading ...; fig 3d	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunohistochemistry on mouse samples (fig 5f) and in western blot on human samples (fig 3d). J Clin Invest (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; 1:1000; loading ...; fig s5c	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on mouse samples at 1:1000 (fig s5c). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	ChIP-Seq; human; 1:50; loading ...; fig 3a immunoprecipitation; human; 1:500; fig 1d, 1e western blot; human; 1:1000; loading ...; fig 1b	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in ChIP-Seq on human samples at 1:50 (fig 3a), in immunoprecipitation on human samples at 1:500 (fig 1d, 1e) and in western blot on human samples at 1:1000 (fig 1b). elife (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1a, 1b, 1c, 1d	Cell Signaling Technology Ezh2 antibody (CST, D2C9) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1a, 1b, 1c, 1d). Clin Epigenetics (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry knockout validation; mouse; loading ...; fig 2a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in immunohistochemistry knockout validation on mouse samples (fig 2a). J Bone Miner Res (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1f	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246S) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1f). Neurol Med Chir (Tokyo) (2020) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; human; 1:100; loading ...; fig 4h immunoprecipitation; human; 1:300; loading ...; fig 6e western blot; human; 1:1000; loading ...; fig 4c	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on human samples at 1:100 (fig 4h), in immunoprecipitation on human samples at 1:300 (fig 6e) and in western blot on human samples at 1:1000 (fig 4c). Oncol Rep (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunoprecipitation; human; loading ...; fig s1c western blot; human; 1:1000; loading ...; fig s1b	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunoprecipitation on human samples (fig s1c) and in western blot on human samples at 1:1000 (fig s1b). Sci Adv (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; human; loading ...; fig 4c immunocytochemistry; human; 1:200; loading ...; fig 3s3a, 3s3b, 3s3c western blot; human; 1:1000; loading ...; fig 3d	Cell Signaling Technology Ezh2 antibody (CST, 5246) was used in chromatin immunoprecipitation on human samples (fig 4c), in immunocytochemistry on human samples at 1:200 (fig 3s3a, 3s3b, 3s3c) and in western blot on human samples at 1:1000 (fig 3d). elife (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 4i	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig 4i). Biosci Rep (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	mass cytometry; human; loading ...; fig 3a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technologies, 5246) was used in mass cytometry on human samples (fig 3a). Cell (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; human; 1:100; loading ...; fig 2a western blot; human; 1:1000; loading ...; fig 1f	Cell Signaling Technology Ezh2 antibody (CST, 5246) was used in immunohistochemistry on human samples at 1:100 (fig 2a) and in western blot on human samples at 1:1000 (fig 1f). Nat Commun (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 5a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in western blot on human samples (fig 5a). Cancer Res (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunocytochemistry; human; loading ...; fig 5a western blot; human; loading ...; fig 5b	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in immunocytochemistry on human samples (fig 5a) and in western blot on human samples (fig 5b). Sci Adv (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; 1:1000; loading ...; fig s2	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in western blot on mouse samples at 1:1000 (fig s2). Science (2019) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig s1c	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig s1c). Mol Cell (2019) ncbi
mouse monoclonal (AC22) 3147	immunohistochemistry; mouse; loading ...; fig 1h western blot; mouse; loading ...; fig 1a	Cell Signaling Technology Ezh2 antibody (Cell Signalling, 3147) was used in immunohistochemistry on mouse samples (fig 1h) and in western blot on mouse samples (fig 1a). J Biol Chem (2018) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; mouse; loading ...; fig 1h western blot; mouse; loading ...; fig 1a	Cell Signaling Technology Ezh2 antibody (Cell Signalling, 5246) was used in immunohistochemistry on mouse samples (fig 1h) and in western blot on mouse samples (fig 1a). J Biol Chem (2018) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - frozen section; mouse; loading ...; fig 5b flow cytometry; mouse; loading ...; fig 5a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, D2C9) was used in immunohistochemistry - frozen section on mouse samples (fig 5b) and in flow cytometry on mouse samples (fig 5a). J Cell Biol (2018) ncbi
domestic rabbit monoclonal (D2C9) 5246	flow cytometry; mouse; loading ...; fig s3b	Cell Signaling Technology Ezh2 antibody (Cell Signalling Technologies, D2C9) was used in flow cytometry on mouse samples (fig s3b). Cell Discov (2018) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunocytochemistry; human; fig 3f western blot; human; 1:1000; loading ...; fig 3a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunocytochemistry on human samples (fig 3f) and in western blot on human samples at 1:1000 (fig 3a). Cell Death Dis (2018) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; loading ...; fig s15a	In order to investigate the function of lncRNA in the promotion of viral replication, Cell Signaling Technology Ezh2 antibody (CST, 5246) was used in western blot on mouse samples (fig s15a). Science (2017) ncbi
domestic rabbit polyclonal 4905	western blot; human; fig 1f	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 4905) was used in western blot on human samples (fig 1f). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:1000; loading ...; fig 4a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in western blot on human samples at 1:1000 (fig 4a). Sci Rep (2017) ncbi
mouse monoclonal (AC22) 3147	immunocytochemistry; human; loading ...; fig 2c western blot; human; loading ...; fig 2a	In order to investigate the oncogenic functions of CHD4, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in immunocytochemistry on human samples (fig 2c) and in western blot on human samples (fig 2a). Cancer Cell (2017) ncbi
domestic rabbit polyclonal 4905	RNA immunoprecipitation; human; loading ...; fig 5g chromatin immunoprecipitation; human; loading ...; fig 6e western blot; human; 1:1000; loading ...; fig 5c	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 4905S) was used in RNA immunoprecipitation on human samples (fig 5g), in chromatin immunoprecipitation on human samples (fig 6e) and in western blot on human samples at 1:1000 (fig 5c). Oncotarget (2017) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunoprecipitation; human; loading ...; fig 1b immunocytochemistry; human; 5 ug/ml; loading ...; fig 1c western blot; human; loading ...; fig 2b	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246s) was used in immunoprecipitation on human samples (fig 1b), in immunocytochemistry on human samples at 5 ug/ml (fig 1c) and in western blot on human samples (fig 2b). Biomed Pharmacother (2017) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 3d	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig 3d). Cell Rep (2017) ncbi
mouse monoclonal (AC22) 3147	western blot; human; 1:1000; loading ...; fig s10	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in western blot on human samples at 1:1000 (fig s10). Nat Chem Biol (2017) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; loading ...; fig 4e	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246S) was used in western blot on mouse samples (fig 4e). J Immunol (2017) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunoprecipitation; human; loading ...; fig 3a western blot; human; 1:1000; loading ...; fig 1e	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunoprecipitation on human samples (fig 3a) and in western blot on human samples at 1:1000 (fig 1e). Nat Med (2017) ncbi
mouse monoclonal (AC22) 3147	immunohistochemistry - paraffin section; human; loading ...; fig 1a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Nat Med (2017) ncbi
mouse monoclonal (AC22) 3147	western blot; human; loading ...; fig 4b	In order to study how the Notch-lncRNA axis mediates self-renewal of glioma cells, Cell Signaling Technology Ezh2 antibody (Cell signaling, 3147) was used in western blot on human samples (fig 4b). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunoprecipitation; mouse; fig s6 western blot; mouse; 1:1000; fig s3	Cell Signaling Technology Ezh2 antibody (Cell signaling, 5246) was used in immunoprecipitation on mouse samples (fig s6) and in western blot on mouse samples at 1:1000 (fig s3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - paraffin section; mouse; 1:50 western blot; mouse; 1:1000; loading ...; fig 1a immunohistochemistry - paraffin section; human; 1:50 western blot; human; 1:1000; loading ...; fig 3a	In order to elucidate how EZH2 ubiquitination contributes to castration-resistant prostate cancer, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunohistochemistry - paraffin section on mouse samples at 1:50, in western blot on mouse samples at 1:1000 (fig 1a), in immunohistochemistry - paraffin section on human samples at 1:50 and in western blot on human samples at 1:1000 (fig 3a). Oncogene (2017) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1c western blot; mouse; 1:500; fig 1d western blot; human; 1:500; loading ...; fig 2a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 1c), in western blot on mouse samples at 1:500 (fig 1d) and in western blot on human samples at 1:500 (fig 2a). Physiol Rep (2016) ncbi
mouse monoclonal (AC22) 3147	immunoprecipitation; human; fig 5 immunocytochemistry; human; fig 3 western blot; human; fig 5	In order to investigate the functions of EZH2 in human T cells, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in immunoprecipitation on human samples (fig 5), in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 5). Cell Death Dis (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; fig 6	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig 6). Genome Biol (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:1000; fig 2b,4b,7b	Cell Signaling Technology Ezh2 antibody (CST, 5246) was used in western blot on human samples at 1:1000 (fig 2b,4b,7b). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot knockout validation; mouse; fig 1c	Cell Signaling Technology Ezh2 antibody (CST, 5246) was used in western blot knockout validation on mouse samples (fig 1c). J Exp Med (2016) ncbi
mouse monoclonal (AC22) 3147	western blot; human; loading ...; fig s6	In order to elucidate how p21 is suppressed in embryonic stem cells, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in western blot on human samples (fig s6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:1000; fig 4	Cell Signaling Technology Ezh2 antibody (Cell Signalling, 5246) was used in western blot on human samples at 1:1000 (fig 4). Sci Rep (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 1e	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig 1e). Science (2016) ncbi
mouse monoclonal (AC22) 3147	western blot; mouse; fig 4	In order to assess the molecular reader and transcriptional co-regulator of H3k4me2/3 called PHF13, Cell Signaling Technology Ezh2 antibody (Cell Signalling, 3147) was used in western blot on mouse samples (fig 4). elife (2016) ncbi
mouse monoclonal (AC22) 3147	western blot; mouse; fig s12d	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in western blot on mouse samples (fig s12d). Science (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; fig 1	Cell Signaling Technology Ezh2 antibody (Cell signaling, 5246) was used in western blot on human samples (fig 1). J Biol Chem (2016) ncbi
mouse monoclonal (AC22) 3147	western blot; human; loading ...; fig 3c	In order to examine miR26A1 methylation and expression levels in chronic lymphocytic leukemia and mantle cell lymphoma samples, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in western blot on human samples (fig 3c). Epigenetics (2016) ncbi
domestic rabbit polyclonal 4905	western blot; human; loading ...; fig 7a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 4905) was used in western blot on human samples (fig 7a). Oncotarget (2016) ncbi
mouse monoclonal (AC22) 3147	western blot; human; loading ...; fig 1c	In order to study PCGF2, arsenic trioxide-induced PML-RARA protein degradation and UBE2I inhibition in NB4 cells, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in western blot on human samples (fig 1c). Biochim Biophys Acta (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; fig 8a	In order to study transcription factor Blimp-1 in coordinating plasma cell differentiation, Cell Signaling Technology Ezh2 antibody (Cell Signaling, D2C9) was used in western blot on mouse samples (fig 8a). Nat Immunol (2016) ncbi
mouse monoclonal (AC22) 3147	western blot; human; fig 4b	In order to learn about vulnerability in Ewing sarcoma by splicing of the EWS-FLI1 fusion transcript discovered thrugh functional genomic screening, Cell Signaling Technology Ezh2 antibody (Cell signaling, 3147) was used in western blot on human samples (fig 4b). Cell Rep (2016) ncbi
mouse monoclonal (AC22) 3147	western blot; human; fig 3	In order to study promotion of mTORC2-mediated AKT phosphorylation by Yin Yang 1, Cell Signaling Technology Ezh2 antibody (Cell Signaling, AC22) was used in western blot on human samples (fig 3). J Mol Cell Biol (2016) ncbi
domestic rabbit polyclonal 4905	western blot; human; fig 4	In order to study reversal of chemotherapy drug resistance in cervical cancer cells by interference with endogenous EZH2 and up-regulation of Dicer expression, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 4905) was used in western blot on human samples (fig 4). Tumour Biol (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - paraffin section; human; 1:2000; fig 7 western blot; human; 1:2000; loading ...; fig 3e	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunohistochemistry - paraffin section on human samples at 1:2000 (fig 7) and in western blot on human samples at 1:2000 (fig 3e). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (AC22) 3147	immunohistochemistry - paraffin section; mouse; 1:75; fig s1	In order to assess the Wnt-dependent regulation and midbrain-to-forebrain identity switch by loss of Ezh2, Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 3147) was used in immunohistochemistry - paraffin section on mouse samples at 1:75 (fig s1). BMC Biol (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; fig 1	Cell Signaling Technology Ezh2 antibody (Cell signaling, 5246) was used in western blot on human samples (fig 1). Mol Cancer Ther (2016) ncbi
mouse monoclonal (AC22) 3147	western blot knockout validation; human; fig 1	Cell Signaling Technology Ezh2 antibody (Cell Signaling Tech, 3147) was used in western blot knockout validation on human samples (fig 1). Biol Proced Online (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; rat; fig 2 western blot; rat; fig 1	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunohistochemistry on rat samples (fig 2) and in western blot on rat samples (fig 1). Nat Neurosci (2015) ncbi
mouse monoclonal (AC22) 3147	western blot; mouse; fig 7a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147S) was used in western blot on mouse samples (fig 7a). Nat Commun (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:1000; loading ...; fig 1a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples at 1:1000 (fig 1a). Angiogenesis (2016) ncbi
mouse monoclonal (AC22) 3147	chromatin immunoprecipitation; human; fig 4 western blot; human; fig 4	Cell Signaling Technology Ezh2 antibody (Cell Signaling, AC22) was used in chromatin immunoprecipitation on human samples (fig 4) and in western blot on human samples (fig 4). J Virol (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; mouse; fig 6a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in chromatin immunoprecipitation on mouse samples (fig 6a). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig st2	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig st2). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; mouse; fig 1a immunocytochemistry; human; 1:200	Cell Signaling Technology Ezh2 antibody (Cell Signaling, D2C9) was used in western blot on mouse samples (fig 1a) and in immunocytochemistry on human samples at 1:200. Lab Invest (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunocytochemistry; mouse; fig 4	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in immunocytochemistry on mouse samples (fig 4). J Pathol (2015) ncbi
mouse monoclonal (AC22) 3147	immunoprecipitation; mouse; fig 5 western blot; mouse; 1:1000; fig s11	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in immunoprecipitation on mouse samples (fig 5) and in western blot on mouse samples at 1:1000 (fig s11). Genome Res (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; loading ...; fig 7a	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples (fig 7a). PLoS ONE (2015) ncbi
mouse monoclonal (AC22) 3147	western blot; human; 1:3000; fig 7	Cell Signaling Technology Ezh2 antibody (cell Signaling Tech, 3147) was used in western blot on human samples at 1:3000 (fig 7). Mol Cancer (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; human; fig 3 immunoprecipitation; human; fig 3 western blot; human; fig s3	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on human samples (fig 3), in immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig s3). PLoS ONE (2015) ncbi
mouse monoclonal (AC22) 3147	western blot; human; loading ...; fig 1d	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147) was used in western blot on human samples (fig 1d). Oncotarget (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human	In order to study how EpCAM is upregulated in HBV-mediated hepatocellular carcinoma and hepatic cancer stem cells, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples . Oncogene (2016) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:1000; loading ...; fig 6g	Cell Signaling Technology Ezh2 antibody (Cell Signaling, D2C9) was used in western blot on human samples at 1:1000 (fig 6g). Mol Cancer (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunoprecipitation; human immunocytochemistry; human western blot; human	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in immunoprecipitation on human samples , in immunocytochemistry on human samples and in western blot on human samples . Nucleic Acids Res (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunocytochemistry; human; fig s3 western blot; human; fig 2	Cell Signaling Technology Ezh2 antibody (CST, 5246s) was used in immunocytochemistry on human samples (fig s3) and in western blot on human samples (fig 2). Cancer Res (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human	In order to investigate DNA methylation profiles in small cell lung cancer, patient-derived xenografts, and cell lines at single-nucleotide resolution, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in western blot on human samples . Oncogene (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry; rat; 1:1000; fig 3 western blot; rat; 1:1000; fig s4	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246S) was used in immunohistochemistry on rat samples at 1:1000 (fig 3) and in western blot on rat samples at 1:1000 (fig s4). Nat Neurosci (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:200; fig 1 immunohistochemistry; mouse; fig s4	Cell Signaling Technology Ezh2 antibody (Cell Signaling, D2C9) was used in western blot on human samples at 1:200 (fig 1) and in immunohistochemistry on mouse samples (fig s4). Nature (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; zebrafish ; 1:100	In order to identify and study epigenetic mechanisms that contribute to neural crest development, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on zebrafish samples at 1:100. Development (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; human; fig 3	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246S) was used in chromatin immunoprecipitation on human samples (fig 3). Sci Rep (2015) ncbi
mouse monoclonal (AC22) 3147	western blot; human; fig 4	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 3147S) was used in western blot on human samples (fig 4). Sci Rep (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; mouse; fig 3 immunoprecipitation; mouse; fig 3	In order to assess the interaction between Ezh2 and ERK1/2 with Fra-2/AP-1 and regulation of terminal epidermal differentiation, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on mouse samples (fig 3) and in immunoprecipitation on mouse samples (fig 3). Genes Dev (2015) ncbi
mouse monoclonal (AC22) 3147	western blot; mouse; 1:1000; fig 3	In order to assess the interaction between Ezh2 and ERK1/2 with Fra-2/AP-1 and regulation of terminal epidermal differentiation, Cell Signaling Technology Ezh2 antibody (Cell Signaling, AC22) was used in western blot on mouse samples at 1:1000 (fig 3). Genes Dev (2015) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:1000	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, #5246) was used in western blot on human samples at 1:1000. BMC Cancer (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; fig 4a	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used in western blot on human samples (fig 4a). Nature (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	western blot; human; 1:1000; fig s7b	Cell Signaling Technology Ezh2 antibody (Cell Signaling, D2C9) was used in western blot on human samples at 1:1000 (fig s7b). Nat Med (2014) ncbi
mouse monoclonal (AC22) 3147	other; rat; loading ...; fig 5a	Cell Signaling Technology Ezh2 antibody (CST, 3147) was used in other on rat samples (fig 5a). PLoS ONE (2014) ncbi
mouse monoclonal (AC22) 3147	chromatin immunoprecipitation; human; loading ...; fig s4d western blot; human; loading ...; fig s4d	Cell Signaling Technology Ezh2 antibody (Cell signaling, 3147) was used in chromatin immunoprecipitation on human samples (fig s4d) and in western blot on human samples (fig s4d). FASEB J (2015) ncbi
mouse monoclonal (AC22) 3147	western blot; human; fig 1	In order to report that NF-kappaB2 and RelB have multiple effects on the expression of key regulators of the cell cycle, reactive oxygen species generation, and protein stability, Cell Signaling Technology Ezh2 antibody (Cell signaling, 3147S) was used in western blot on human samples (fig 1). PLoS Genet (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - paraffin section; human; 1:300	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technologies, D2C9) was used in immunohistochemistry - paraffin section on human samples at 1:300. PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; mouse	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on mouse samples . Genes Dev (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; mouse	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on mouse samples . PLoS Genet (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	RNA immunoprecipitation; human; loading ...; fig 4a	Cell Signaling Technology Ezh2 antibody (Cell signaling, D2C9) was used in RNA immunoprecipitation on human samples (fig 4a). PLoS ONE (2014) ncbi
mouse monoclonal (AC22) 3147	immunoprecipitation; human	Cell Signaling Technology Ezh2 antibody (Cell Signaling, AC22) was used in immunoprecipitation on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (AC22) 3147	immunohistochemistry - paraffin section; mouse; 1:50	Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, AC22) was used in immunohistochemistry - paraffin section on mouse samples at 1:50. J Neurosci (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; human; 1:100 immunoprecipitation; human; 1:1000 western blot; human; 1:1000	In order to study the Involvement of EED in the organization of polycomb group complexes, Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on human samples at 1:100, in immunoprecipitation on human samples at 1:1000 and in western blot on human samples at 1:1000. Nat Commun (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246	immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1	Cell Signaling Technology Ezh2 antibody (cell signalling, D2C9) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Virchows Arch (2014) ncbi
domestic rabbit monoclonal (D2C9) 5246		Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, 5246) was used . Endocr Relat Cancer (2014) ncbi
mouse monoclonal (AC22) 3147	western blot; mouse	In order to study the role of polycomb repressive complex 2 in leukemia progression, Cell Signaling Technology Ezh2 antibody (Cell Signaling, AC-22) was used in western blot on mouse samples . Blood (2013) ncbi
mouse monoclonal (AC22) 3147	immunocytochemistry; human western blot; human immunohistochemistry; mouse	In order to study the role of chromatin regulator PRC2 in epigenetic plasticity in glioblastoma, Cell Signaling Technology Ezh2 antibody (Cell Signaling Technology, AC22) was used in immunocytochemistry on human samples , in western blot on human samples and in immunohistochemistry on mouse samples . Cancer Res (2013) ncbi
mouse monoclonal (AC22) 3147	immunocytochemistry; human	Cell Signaling Technology Ezh2 antibody (Cell Signaling, AC22) was used in immunocytochemistry on human samples . EMBO J (2013) ncbi
domestic rabbit monoclonal (D2C9) 5246	chromatin immunoprecipitation; human western blot; human	Cell Signaling Technology Ezh2 antibody (Cell Signaling, 5246) was used in chromatin immunoprecipitation on human samples and in western blot on human samples . J Biol Chem (2013) ncbi

BD Biosciences

mouse monoclonal (11/EZH2)

562478

flow cytometry; mouse; loading ...; fig 5e

BD Biosciences Ezh2 antibody (BD, 562478) was used in flow cytometry on mouse samples (fig 5e). Nat Immunol (2016) ncbi

Articles Reviewed

Gonzalez M, Naimo G, Anwar T, Paol xec A, Tekula S, Kim S, et al. EZH2 T367 phosphorylation activates p38 signaling through lysine methylation to promote breast cancer progression. iScience. 2022;25:104827 pubmed publisher
Xing H, Gao M, Wang Y, Zhang X, Shi J, Wang X, et al. Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma. Clin Transl Med. 2022;12:e835 pubmed publisher
Guo T, Han X, He J, Feng J, Jing J, Jane x10d kov xe1 E, et al. KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. elife. 2022;11: pubmed publisher
Wu Q, Shichino Y, Abe T, Suetsugu T, Omori A, Kiyonari H, et al. Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells. Nat Commun. 2022;13:470 pubmed publisher
Zhang Q, Agius S, Flanigan S, Uckelmann M, Levina V, Owen B, et al. PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis. Nat Commun. 2021;12:4592 pubmed publisher
Wei Y, Chen J, Xu X, Li F, Wu K, Jiang Y, et al. Restoration of H3k27me3 Modification Epigenetically Silences Cry1 Expression and Sensitizes Leptin Signaling to Reduce Obesity-Related Properties. Adv Sci (Weinh). 2021;8:2004319 pubmed publisher
Zou S, Gao Y, Zhang S. lncRNA HCP5 acts as a ceRNA to regulate EZH2 by sponging miR‑138‑5p in cutaneous squamous cell carcinoma. Int J Oncol. 2021;59: pubmed publisher
Dong F, Chen M, Jiang L, Shen Z, Ma L, Han C, et al. PRMT5 Is Involved in Spermatogonial Stem Cells Maintenance by Regulating Plzf Expression via Modulation of Lysine Histone Modifications. Front Cell Dev Biol. 2021;9:673258 pubmed publisher
Cheng Z, Naga Srikanth Garikipati V, Truongcao M, CIMINI M, Huang G, Wang C, et al. Serum-Derived Small Extracellular Vesicles From Diabetic Mice Impair Angiogenic Property of Microvascular Endothelial Cells: Role of EZH2. J Am Heart Assoc. 2021;10:e019755 pubmed publisher
Morel K, Sheahan A, Burkhart D, Baca S, Boufaied N, Liu Y, et al. EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer. Nat Cancer. 2021;2:444-456 pubmed publisher
Guo J, Zhu H, Li Q, Dong J, Xiong W, Yu K. SPRY4 suppresses proliferation and induces apoptosis of colorectal cancer cells by repressing oncogene EZH2. Aging (Albany NY). 2021;13:11665-11677 pubmed publisher
Park S, Fong K, Kim J, Wang F, Lu X, Lee Y, et al. Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer. Sci Adv. 2021;7: pubmed publisher
Su S, Li Q, Zhang M, Zhang P, Shen H, Zhang C. An E2F1/DDX11/EZH2 Positive Feedback Loop Promotes Cell Proliferation in Hepatocellular Carcinoma. Front Oncol. 2020;10:593293 pubmed publisher
Tang B, Sun R, Wang D, Sheng H, Wei T, Wang L, et al. ZMYND8 preferentially binds phosphorylated EZH2 to promote a PRC2-dependent to -independent function switch in hypoxia-inducible factor-activated cancer. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Sun X, Chen Y, Yao Q, Chen X, He M, Chen C, et al. MicroRNA-144 Suppresses Prostate Cancer Growth and Metastasis by Targeting EZH2. Technol Cancer Res Treat. 2021;20:1533033821989817 pubmed publisher
Wen Y, Hou Y, Yi X, Sun S, Guo J, He X, et al. EZH2 activates CHK1 signaling to promote ovarian cancer chemoresistance by maintaining the properties of cancer stem cells. Theranostics. 2021;11:1795-1813 pubmed publisher
Bao Y, Oguz G, Lee W, Lee P, Ghosh K, Li J, et al. EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy. Nat Commun. 2020;11:5878 pubmed publisher
Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher
Perkail S, Andricovich J, Kai Y, Tzatsos A. BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice. Nat Commun. 2020;11:3018 pubmed publisher
Jain P, Ballaré C, Blanco E, Vizan P, Di Croce L. PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells. elife. 2020;9: pubmed publisher
Hoffmann F, Niebel D, Aymans P, Ferring Schmitt S, Dietrich D, Landsberg J. H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade. Clin Epigenetics. 2020;12:24 pubmed publisher
Du X, Chen Y, Zhang Q, Lin J, Yu Y, Pan Z, et al. Ezh2 Ameliorates Osteoarthritis by Activating TNFSF13B. J Bone Miner Res. 2020;35:956-965 pubmed publisher
Enomoto T, Aoki M, Hamasaki M, Abe H, Nonaka M, Inoue T, et al. Midline Glioma in Adults: Clinicopathological, Genetic, and Epigenetic Analysis. Neurol Med Chir (Tokyo). 2020;60:136-146 pubmed publisher
Zhang L, Tian S, Pei M, Zhao M, Wang L, Jiang Y, et al. Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer. Oncol Rep. 2019;42:2655-2669 pubmed publisher
Piunti A, Smith E, Morgan M, Ugarenko M, Khaltyan N, Helmin K, et al. CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. Sci Adv. 2019;5:eaax2887 pubmed publisher
Wang C, Zhu C, Xu J, Wang M, Zhao W, Liu Q, et al. The lncRNA UCA1 promotes proliferation, migration, immune escape and inhibits apoptosis in gastric cancer by sponging anti-tumor miRNAs. Mol Cancer. 2019;18:115 pubmed publisher
Azkanaz M, Rodríguez López A, de Boer B, Huiting W, Angrand P, Vellenga E, et al. Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock. elife. 2019;8: pubmed publisher
Fan M, Zou Y, He P, Zhang S, Sun X, Li C. Long non-coding RNA SPRY4-IT1 promotes epithelial-mesenchymal transition of cervical cancer by regulating the miR-101-3p/ZEB1 axis. Biosci Rep. 2019;: pubmed publisher
Wagner J, Rapsomaniki M, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, et al. A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer. Cell. 2019;177:1330-1345.e18 pubmed publisher
Lima Fernandes E, Murison A, da Silva Medina T, Wang Y, Ma A, Leung C, et al. Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells. Nat Commun. 2019;10:1436 pubmed publisher
Wang Z, Feng X, Molinolo A, Martin D, Vitale Cross L, Nohata N, et al. 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer. Cancer Res. 2019;: pubmed publisher
Wei X, Guo J, Li Q, Jia Q, Jing Q, Li Y, et al. Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. Sci Adv. 2019;5:eaau7887 pubmed publisher
Chakraborty A, Laukka T, Myllykoski M, Ringel A, Booker M, Tolstorukov M, et al. Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate. Science. 2019;363:1217-1222 pubmed publisher
Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher
Meisenberg C, Pinder S, Hopkins S, Wooller S, Benstead Hume G, Pearl F, et al. Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability. Mol Cell. 2019;73:212-223.e7 pubmed publisher
Ferreira M, Verbinnen I, Fardilha M, Van Eynde A, Bollen M. The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2. J Biol Chem. 2018;293:18031-18039 pubmed publisher
Hervás Corpión I, Guiretti D, Alcaraz Iborra M, Olivares R, Campos Caro A, Barco A, et al. Early alteration of epigenetic-related transcription in Huntington's disease mouse models. Sci Rep. 2018;8:9925 pubmed publisher
Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
Rothberg J, Maganti H, Jrade H, Porter C, Palidwor G, Cafariello C, et al. Mtf2-PRC2 control of canonical Wnt signaling is required for definitive erythropoiesis. Cell Discov. 2018;4:21 pubmed publisher
Lino Cardenas C, Kessinger C, Cheng Y, MacDonald C, Macgillivray T, Ghoshhajra B, et al. An HDAC9-MALAT1-BRG1 complex mediates smooth muscle dysfunction in thoracic aortic aneurysm. Nat Commun. 2018;9:1009 pubmed publisher
Le Duff M, Gouju J, Jonchère B, Guillon J, Toutain B, Boissard A, et al. Regulation of senescence escape by the cdk4-EZH2-AP2M1 pathway in response to chemotherapy. Cell Death Dis. 2018;9:199 pubmed publisher
Wang P, Xu J, Wang Y, Cao X. An interferon-independent lncRNA promotes viral replication by modulating cellular metabolism. Science. 2017;358:1051-1055 pubmed publisher
Wang J, Cheng P, Pavlyukov M, Yu H, Zhang Z, Kim S, et al. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2. J Clin Invest. 2017;127:3075-3089 pubmed publisher
Patel N, Garikapati K, Pandita R, Singh D, Pandita T, Bhadra U, et al. miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017;7:4263 pubmed publisher
Xia L, Huang W, Bellani M, Seidman M, Wu K, Fan D, et al. CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes. Cancer Cell. 2017;31:653-668.e7 pubmed publisher
Huo Y, Li Q, Wang X, Jiao X, Zheng J, Li Z, et al. MALAT1 predicts poor survival in osteosarcoma patients and promotes cell metastasis through associating with EZH2. Oncotarget. 2017;8:46993-47006 pubmed publisher
Jin Y, Huo B, Fu X, Hao T, Zhang Y, Guo Y, et al. LSD1 collaborates with EZH2 to regulate expression of interferon-stimulated genes. Biomed Pharmacother. 2017;88:728-737 pubmed publisher
Gonzalez M, Martin E, Anwar T, Arellano Garcia C, Medhora N, Lama A, et al. Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth. Cell Rep. 2017;18:1215-1228 pubmed publisher
He Y, Selvaraju S, Curtin M, Jakob C, Zhu H, Comess K, et al. The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complex. Nat Chem Biol. 2017;13:389-395 pubmed publisher
Lyroni K, Patsalos A, Daskalaki M, Doxaki C, Soennichsen B, Helms M, et al. Epigenetic and Transcriptional Regulation of IRAK-M Expression in Macrophages. J Immunol. 2017;198:1297-1307 pubmed publisher
Göllner S, Oellerich T, Agrawal Singh S, Schenk T, Klein H, Rohde C, et al. Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nat Med. 2017;23:69-78 pubmed publisher
Katsushima K, Natsume A, Ohka F, Shinjo K, Hatanaka A, Ichimura N, et al. Targeting the Notch-regulated non-coding RNA TUG1 for glioma treatment. Nat Commun. 2016;7:13616 pubmed publisher
Cooper S, Grijzenhout A, Underwood E, Ancelin K, Zhang T, Nesterova T, et al. Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2. Nat Commun. 2016;7:13661 pubmed publisher
Lu W, Liu S, Li B, Xie Y, Izban M, Ballard B, et al. SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer. Oncogene. 2017;36:1364-1373 pubmed publisher
Gerriets V, Kishton R, Johnson M, Cohen S, Siska P, Nichols A, et al. Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression. Nat Immunol. 2016;17:1459-1466 pubmed publisher
Xiao X, Senavirathna L, Gou X, Huang C, Liang Y, Liu L. EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis. Physiol Rep. 2016;4: pubmed publisher
Goto Y, Kurozumi A, Nohata N, Kojima S, Matsushita R, Yoshino H, et al. The microRNA signature of patients with sunitinib failure: regulation of UHRF1 pathways by microRNA-101 in renal cell carcinoma. Oncotarget. 2016;7:59070-59086 pubmed publisher
Wang Y, Sun H, Wang J, Wang H, Meng L, Xu C, et al. DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity. Cell Death Dis. 2016;7:e2316 pubmed publisher
Nelson D, Jaber Hijazi F, Cole J, Robertson N, Pawlikowski J, Norris K, et al. Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability. Genome Biol. 2016;17:158 pubmed publisher
Grinshtein N, Rioseco C, Marcellus R, UEHLING D, Aman A, Lun X, et al. Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells. Oncotarget. 2016;7:59360-59376 pubmed publisher
Sashida G, Wang C, Tomioka T, Oshima M, Aoyama K, Kanai A, et al. The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition. J Exp Med. 2016;213:1459-77 pubmed publisher
Itahana Y, Zhang J, GÃ¶ke J, Vardy L, Han R, Iwamoto K, et al. Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. Sci Rep. 2016;6:28112 pubmed publisher
Li J, Zhang S, Hu Q, Zhang K, Jin J, Zheng X, et al. The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocarcinoma cells. Sci Rep. 2016;6:26971 pubmed publisher
Fang D, Gan H, Lee J, Han J, Wang Z, Riester S, et al. The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas. Science. 2016;352:1344-8 pubmed publisher
Chung H, Xu C, Fuchs A, Mund A, Lange M, Staege H, et al. PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. elife. 2016;5: pubmed publisher
Lu C, Jain S, Hoelper D, Bechet D, Molden R, Ran L, et al. Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science. 2016;352:844-9 pubmed publisher
Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, et al. HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis. J Biol Chem. 2016;291:12688-705 pubmed publisher
Kopparapu P, Bhoi S, Mansouri L, Arabanian L, Plevova K, Pospisilova S, et al. Epigenetic silencing of miR-26A1 in chronic lymphocytic leukemia and mantle cell lymphoma: Impact on EZH2 expression. Epigenetics. 2016;11:335-43 pubmed publisher
Li X, Dai X, Wan L, Inuzuka H, Sun L, North B. Smurf1 regulation of DAB2IP controls cell proliferation and migration. Oncotarget. 2016;7:26057-69 pubmed publisher
Jo S, Lee Y, Kim S, Lee H, Chung H. PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells. Biochim Biophys Acta. 2016;1863:1499-509 pubmed publisher
Minnich M, Tagoh H, BÃ¶nelt P, Axelsson E, Fischer M, Cebolla B, et al. Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation. Nat Immunol. 2016;17:331-43 pubmed publisher
Grohar P, Kim S, Rangel Rivera G, Sen N, Haddock S, Harlow M, et al. Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma. Cell Rep. 2016;14:598-610 pubmed publisher
Zhang Q, Wan M, Shi J, Horita D, Miller L, Kute T, et al. Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation. J Mol Cell Biol. 2016;8:232-43 pubmed publisher
Cai L, Wang Z, Liu D. Interference with endogenous EZH2 reverses the chemotherapy drug resistance in cervical cancer cells partly by up-regulating Dicer expression. Tumour Biol. 2016;37:6359-69 pubmed publisher
Sengupta D, Byrum S, Avaritt N, Davis L, Shields B, Mahmoud F, et al. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics. 2016;15:765-75 pubmed publisher
Zemke M, Draganova K, Klug A, SchÃ¶ler A, Zurkirchen L, Gay M, et al. Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation. BMC Biol. 2015;13:103 pubmed publisher
Hernando H, Gelato K, Lesche R, Beckmann G, Koehr S, Otto S, et al. EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes. Mol Cancer Ther. 2016;15:287-98 pubmed publisher
Grassian A, Scales T, Knutson S, Kuntz K, McCarthy N, Lowe C, et al. A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality. Biol Proced Online. 2015;17:15 pubmed publisher
Laumet G, Garriga J, Chen S, Zhang Y, Li D, Smith T, et al. G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition. Nat Neurosci. 2015;18:1746-55 pubmed publisher
Oravecz A, Apostolov A, Polak K, Jost B, Le Gras S, Chan S, et al. Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2. Nat Commun. 2015;6:8823 pubmed publisher
Wongtrakoongate P, Riddick G, Fucharoen S, Felsenfeld G. Association of the Long Non-coding RNA Steroid Receptor RNA Activator (SRA) with TrxG and PRC2 Complexes. PLoS Genet. 2015;11:e1005615 pubmed publisher
Maleszewska M, Vanchin B, Harmsen M, Krenning G. The decrease in histone methyltransferase EZH2 in response to fluid shear stress alters endothelial gene expression and promotes quiescence. Angiogenesis. 2016;19:9-24 pubmed publisher
Hu P, Chu J, Wu Y, Sun L, Lv X, Zhu Y, et al. NBAT1 suppresses breast cancer metastasis by regulating DKK1 via PRC2. Oncotarget. 2015;6:32410-25 pubmed publisher
Pacini L, Savini C, Ghittoni R, Saidj D, Lamartine J, Hasan U, et al. Downregulation of Toll-Like Receptor 9 Expression by Beta Human Papillomavirus 38 and Implications for Cell Cycle Control. J Virol. 2015;89:11396-405 pubmed publisher
Zha L, Li F, Wu R, Artinian L, Rehder V, Yu L, et al. The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation. J Biol Chem. 2015;290:25151-63 pubmed publisher
Tiffen J, Gunatilake D, Gallagher S, Gowrishankar K, Heinemann A, Cullinane C, et al. Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes. Oncotarget. 2015;6:27023-36 pubmed publisher
Khan M, Walters L, Li Q, Thomas D, Miller J, Zhang Q, et al. Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma. Lab Invest. 2015;95:1278-90 pubmed publisher
McCleland M, Soukup T, Liu S, Esensten J, De Sousa E Melo F, Yaylaoglu M, et al. Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis. J Pathol. 2015;237:508-19 pubmed publisher
Fei Q, Yang X, Jiang H, Wang Q, Yu Y, Yu Y, et al. SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells. Genome Res. 2015;25:1325-35 pubmed publisher
Kotomura N, Harada N, Ishihara S. The Proportion of Chromatin Graded between Closed and Open States Determines the Level of Transcripts Derived from Distinct Promoters in the CYP19 Gene. PLoS ONE. 2015;10:e0128282 pubmed publisher
Heubach J, Monsior J, Deenen R, Niegisch G, Szarvas T, Niedworok C, et al. The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells. Mol Cancer. 2015;14:108 pubmed publisher
Nishioka C, Ikezoe T, Yang J, Yokoyama A. Tetraspanin Family Member, CD82, Regulates Expression of EZH2 via Inactivation of p38 MAPK Signaling in Leukemia Cells. PLoS ONE. 2015;10:e0125017 pubmed publisher
Chen H, Gao S, Li J, Liu D, Sheng C, Yao C, et al. Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer. Oncotarget. 2015;6:13049-59 pubmed
Fan H, Zhang H, Pascuzzi P, Andrisani O. Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2. Oncogene. 2016;35:715-26 pubmed publisher
Zhang P, Yang X, Ma X, Ingram D, Lazar A, Torres K, et al. Antitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway. Mol Cancer. 2015;14:55 pubmed publisher
Wan J, Zhan J, Li S, Ma J, Xu W, Liu C, et al. PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression. Nucleic Acids Res. 2015;43:3591-604 pubmed publisher
Zhou Q, Derti A, Ruddy D, Rakiec D, Kao I, Lira M, et al. A chemical genetics approach for the functional assessment of novel cancer genes. Cancer Res. 2015;75:1949-58 pubmed publisher
Poirier J, Gardner E, Connis N, Moreira A, de Stanchina E, Hann C, et al. DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2. Oncogene. 2015;34:5869-78 pubmed publisher
de la Cruz Hernandez E, Medina Franco J, Trujillo J, Chavez Blanco A, Domínguez Gómez G, Perez Cardenas E, et al. Ribavirin as a tri-targeted antitumor repositioned drug. Oncol Rep. 2015;33:2384-92 pubmed publisher
Koo J, Mazei Robison M, LaPlant Q, Egervári G, Braunscheidel K, Adank D, et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci. 2015;18:415-22 pubmed publisher
Fillmore C, Xu C, Desai P, Berry J, Rowbotham S, Lin Y, et al. EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors. Nature. 2015;520:239-42 pubmed publisher
Ranzani V, Rossetti G, Panzeri I, Arrigoni A, Bonnal R, Curti S, et al. The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nat Immunol. 2015;16:318-325 pubmed publisher
Tien C, Jones A, Wang H, Gerigk M, Nozell S, Chang C. Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development. Development. 2015;142:722-31 pubmed publisher
Matsuda Y, Kobayashi Ishihara M, Fujikawa D, Ishida T, Watanabe T, Yamagishi M. Epigenetic heterogeneity in HIV-1 latency establishment. Sci Rep. 2015;5:7701 pubmed publisher
Wurm S, Zhang J, Guinea Viniegra J, GarcÃa F, MuÃ±oz J, Bakiri L, et al. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2. Genes Dev. 2015;29:144-56 pubmed publisher
Naganuma K, Hatta M, Ikebe T, Yamazaki J. Epigenetic alterations of the keratin 13 gene in oral squamous cell carcinoma. BMC Cancer. 2014;14:988 pubmed publisher
Bhatnagar S, Gazin C, Chamberlain L, Ou J, Zhu X, Tushir J, et al. TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein. Nature. 2014;516:116-20 pubmed publisher
Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, et al. Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma. Nat Med. 2014;20:1394-6 pubmed publisher
Englert N, Luo G, Goldstein J, Surapureddi S. Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9. J Biol Chem. 2015;290:2264-78 pubmed publisher
Atta H, El Rehany M, Hammam O, Abdel Ghany H, Ramzy M, Roderfeld M, et al. Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS ONE. 2014;9:e112384 pubmed publisher
Kim H, Park J, Won H, Lee J, Kong G. CBX7 inhibits breast tumorigenicity through DKK-1-mediated suppression of the Wnt/Î²-catenin pathway. FASEB J. 2015;29:300-13 pubmed publisher
Iannetti A, Ledoux A, Tudhope S, Sellier H, Zhao B, Mowla S, et al. Regulation of p53 and Rb links the alternative NF-ÎºB pathway to EZH2 expression and cell senescence. PLoS Genet. 2014;10:e1004642 pubmed publisher
Karoopongse E, Yeung C, Byon J, Ramakrishnan A, Holman Z, Jiang P, et al. The KDM2B- let-7b -EZH2 axis in myelodysplastic syndromes as a target for combined epigenetic therapy. PLoS ONE. 2014;9:e107817 pubmed publisher
Lu F, Liu Y, Jiang L, Yamaguchi S, Zhang Y. Role of Tet proteins in enhancer activity and telomere elongation. Genes Dev. 2014;28:2103-19 pubmed publisher
Shpargel K, Starmer J, Yee D, Pohlers M, Magnuson T. KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development. PLoS Genet. 2014;10:e1004507 pubmed publisher
Sun N, Ye C, Zhao Q, Zhang Q, Xu C, Wang S, et al. Long noncoding RNA-EBIC promotes tumor cell invasion by binding to EZH2 and repressing E-cadherin in cervical cancer. PLoS ONE. 2014;9:e100340 pubmed publisher
Negishi M, Wongpalee S, Sarkar S, Park J, Lee K, Shibata Y, et al. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. PLoS ONE. 2014;9:e95216 pubmed publisher
Piper M, Barry G, Harvey T, McLeay R, Smith A, Harris L, et al. NFIB-mediated repression of the epigenetic factor Ezh2 regulates cortical development. J Neurosci. 2014;34:2921-30 pubmed publisher
Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, et al. The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127 pubmed publisher
Hayashi A, Morikawa T, Kawai T, Kume H, Ishikawa S, Homma Y, et al. Clinicopathological and prognostic significance of EZH2 expression in upper urinary tract carcinoma. Virchows Arch. 2014;464:463-71 pubmed publisher
Svedlund J, Barazeghi E, Stalberg P, Hellman P, Akerstrom G, Björklund P, et al. The histone methyltransferase EZH2, an oncogene common to benign and malignant parathyroid tumors. Endocr Relat Cancer. 2014;21:231-9 pubmed publisher
Wang A, Pan D, Lee Y, Martinez G, Feng X, Dong C. Cutting edge: Smad2 and Smad4 regulate TGF-?-mediated Il9 gene expression via EZH2 displacement. J Immunol. 2013;191:4908-12 pubmed publisher
Lee S, Phipson B, Hyland C, Leong H, Allan R, Lun A, et al. Polycomb repressive complex 2 (PRC2) suppresses E?-myc lymphoma. Blood. 2013;122:2654-63 pubmed publisher
Bengani H, Mendiratta S, Maini J, Vasanthi D, Sultana H, Ghasemi M, et al. Identification and Validation of a Putative Polycomb Responsive Element in the Human Genome. PLoS ONE. 2013;8:e67217 pubmed publisher
Natsume A, Ito M, Katsushima K, Ohka F, Hatanaka A, Shinjo K, et al. Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma. Cancer Res. 2013;73:4559-70 pubmed publisher
Rossetto C, Tarrant Elorza M, Pari G. Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells. PLoS Pathog. 2013;9:e1003366 pubmed publisher
Martin N, Popov N, Aguilo F, O Loghlen A, Raguz S, Snijders A, et al. Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation. EMBO J. 2013;32:982-95 pubmed publisher
Corvetta D, Chayka O, Gherardi S, D Acunto C, Cantilena S, Valli E, et al. Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. J Biol Chem. 2013;288:8332-41 pubmed publisher
Lin S, Shen H, Li J, Tang S, Gu Y, Chen Z, et al. Proteomic and functional analyses reveal the role of chromatin reader SFMBT1 in regulating epigenetic silencing and the myogenic gene program. J Biol Chem. 2013;288:6238-47 pubmed publisher
Murata T, Kondo Y, Sugimoto A, Kawashima D, Saito S, Isomura H, et al. Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells. J Virol. 2012;86:4752-61 pubmed publisher

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