This is a Validated Antibody Database (VAD) review about mouse Ephb4, based on 11 published articles (read how Labome selects the articles), using Ephb4 antibody in all methods. It is aimed to help Labome visitors find the most suited Ephb4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ephb4 synonym: AI042935; Htk; MDK2; Myk1; Tyro11; b2b2412Clo; ephrin type-B receptor 4; developmental kinase 2; hepatoma transmembrane kinase; mDK-2; tyrosine kinase MYK-1

R&D Systems
goat polyclonal
  • western blot; mouse; loading ...; fig 1a
R&D Systems Ephb4 antibody (R&D, AF446) was used in western blot on mouse samples (fig 1a). Sci Rep (2017) ncbi
goat polyclonal
  • immunohistochemistry; mouse; fig s4
In order to identify EPHB4 as a critical regulator of early lymphatic vascular development and show that mutation of this gene are associated with lymphatic-related (nonimmune) hydrops fetalis, R&D Systems Ephb4 antibody (R&D, AF446) was used in immunohistochemistry on mouse samples (fig s4). J Clin Invest (2016) ncbi
goat polyclonal
  • western blot; rat; 1:1000; fig 4
R&D Systems Ephb4 antibody (R&D, AF446) was used in western blot on rat samples at 1:1000 (fig 4). Physiol Rep (2016) ncbi
goat polyclonal
  • immunohistochemistry - frozen section; mouse; fig 2
In order to compare valve phenotypes of Cx37, Cx43, and Cx47 knockout mice by NFATc1 and connexin expression in normal developing venous valves, segregated Foxc2, and connexin-specific differences, R&D Systems Ephb4 antibody (R&D Systems, AF446) was used in immunohistochemistry - frozen section on mouse samples (fig 2). Dev Biol (2016) ncbi
goat polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; tbl 4
R&D Systems Ephb4 antibody (R&D System, AF446) was used in immunohistochemistry - paraffin section on human samples (tbl 4). Chin J Cancer (2016) ncbi
goat polyclonal
  • western blot; human
In order to study the role of ADAM17 in cellular senescence and senescence secretome, R&D Systems Ephb4 antibody (R&D Systems, AF446) was used in western blot on human samples . Breast Cancer Res (2015) ncbi
goat polyclonal
  • immunohistochemistry; mouse; fig s5
In order to demonstrate that the Cdk5-Foxc2 interaction regulates lymphatic vessel development, R&D Systems Ephb4 antibody (R&D Systems, AF446) was used in immunohistochemistry on mouse samples (fig s5). Nat Commun (2015) ncbi
goat polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100
R&D Systems Ephb4 antibody (R&D Systems, AF446) was used in immunohistochemistry - frozen section on mouse samples at 1:100. Development (2013) ncbi
goat polyclonal
  • immunohistochemistry - frozen section; mouse
In order to investigate the role of Cx37 during vasculogenesis in mice, R&D Systems Ephb4 antibody (R&D Systems, AF446) was used in immunohistochemistry - frozen section on mouse samples . Dev Biol (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (5G2F8)
  • western blot; mouse; fig 3d
Santa Cruz Biotechnology Ephb4 antibody (santa cruz, sc-130081) was used in western blot on mouse samples (fig 3d). Int J Mol Med (2016) ncbi
Abcam
rat monoclonal (RM0056-6A14)
  • proximity ligation assay; mouse; fig 3
Abcam Ephb4 antibody (abcam, ab73259) was used in proximity ligation assay on mouse samples (fig 3). Sci Rep (2016) ncbi
Articles Reviewed
  1. Protack C, Foster T, Hashimoto T, Yamamoto K, Lee M, Kraehling J, et al. Eph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency. Sci Rep. 2017;7:15386 pubmed publisher
  2. Martin Almedina S, Martínez Corral I, Holdhus R, Vicente A, Fotiou E, Lin S, et al. EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis. J Clin Invest. 2016;126:3080-8 pubmed publisher
  3. Bai H, Wang M, Foster T, Hu H, He H, Hashimoto T, et al. Pericardial patch venoplasty heals via attraction of venous progenitor cells. Physiol Rep. 2016;4: pubmed publisher
  4. Chen I, Caprioli A, Ohnuki H, Kwak H, Porcher C, Tosato G. EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta. Sci Rep. 2016;6:27195 pubmed publisher
  5. Munger S, Geng X, Srinivasan R, Witte M, Paul D, Simon A. Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016;412:173-90 pubmed publisher
  6. Adighibe O, Leek R, Fernandez Mercado M, Hu J, Snell C, Gatter K, et al. Why some tumours trigger neovascularisation and others don't: the story thus far. Chin J Cancer. 2016;35:18 pubmed publisher
  7. Wu M, Ai W, Chen L, Zhao S, Liu E. Bradykinin receptors and EphB2/EphrinB2 pathway in response to high glucose-induced osteoblast dysfunction and hyperglycemia-induced bone deterioration in mice. Int J Mol Med. 2016;37:565-74 pubmed publisher
  8. Morancho B, Martínez Barriocanal Ã, Villanueva J, Arribas J. Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence. Breast Cancer Res. 2015;17:106 pubmed publisher
  9. Liebl J, Zhang S, Moser M, Agalarov Y, Demir C, Hager B, et al. Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 pubmed publisher
  10. Davis R, Curtis C, Griffin C. BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development. Development. 2013;140:1272-81 pubmed publisher
  11. Munger S, Kanady J, Simon A. Absence of venous valves in mice lacking Connexin37. Dev Biol. 2013;373:338-48 pubmed publisher