This is a Validated Antibody Database (VAD) review about mouse Ep300, based on 20 published articles (read how Labome selects the articles), using Ep300 antibody in all methods. It is aimed to help Labome visitors find the most suited Ep300 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ep300 synonym: A430090G16; A730011L11; KAT3B; p300; p300 HAT

Santa Cruz Biotechnology
mouse monoclonal (F-4)
  • immunohistochemistry - frozen section; rat; 1:200; loading ...; fig 6b
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-48343) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 6b). Histochem Cell Biol (2021) ncbi
mouse monoclonal (NM11)
  • immunohistochemistry; mouse; loading ...; fig 4d
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-32244) was used in immunohistochemistry on mouse samples (fig 4d). Cell Rep (2020) ncbi
mouse monoclonal (SPM307)
  • immunoprecipitation; mouse; loading ...; fig 5l
  • western blot; mouse; loading ...; fig 5l
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-56455) was used in immunoprecipitation on mouse samples (fig 5l) and in western blot on mouse samples (fig 5l). Sci Adv (2019) ncbi
mouse monoclonal (NM11)
  • western blot; human; 1:500; loading ...; fig s11a
Santa Cruz Biotechnology Ep300 antibody (Santa, sc-32244) was used in western blot on human samples at 1:500 (fig s11a). Nat Commun (2019) ncbi
mouse monoclonal (F-4)
  • immunoprecipitation; human; loading ...; fig 7b
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology Inc, sc-48343) was used in immunoprecipitation on human samples (fig 7b). Nucleic Acids Res (2018) ncbi
mouse monoclonal (NM11)
  • western blot; human; loading ...; fig 6d
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, SC-32244) was used in western blot on human samples (fig 6d). J Exp Med (2018) ncbi
mouse monoclonal (F-4)
  • chromatin immunoprecipitation; human; fig 2h
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-48343X) was used in chromatin immunoprecipitation on human samples (fig 2h). Cancer Res (2018) ncbi
mouse monoclonal (F-4)
  • proximity ligation assay; mouse; fig 3f
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-48343) was used in proximity ligation assay on mouse samples (fig 3f). Nat Commun (2015) ncbi
mouse monoclonal (F-4)
  • chromatin immunoprecipitation; rat; fig  6
  • western blot; rat; 1:1000; fig 8
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-48343) was used in chromatin immunoprecipitation on rat samples (fig  6) and in western blot on rat samples at 1:1000 (fig 8). J Neurosci (2015) ncbi
mouse monoclonal (NM11)
  • chromatin immunoprecipitation; African green monkey
  • western blot; African green monkey
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-32244) was used in chromatin immunoprecipitation on African green monkey samples and in western blot on African green monkey samples . J Biol Chem (2014) ncbi
mouse monoclonal (F-4)
  • western blot; human
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz Biotechnology, sc-48343) was used in western blot on human samples . PLoS ONE (2012) ncbi
mouse monoclonal (NM11)
  • immunohistochemistry - paraffin section; rat; 1:300
Santa Cruz Biotechnology Ep300 antibody (Santa Cruz, sc-32244) was used in immunohistochemistry - paraffin section on rat samples at 1:300. Cell Mol Neurobiol (2013) ncbi
Abcam
domestic rabbit monoclonal (EPR23495-268)
  • western blot; mouse; loading ...; fig 4d
Abcam Ep300 antibody (Abcam, ab275378) was used in western blot on mouse samples (fig 4d). Front Immunol (2022) ncbi
domestic rabbit monoclonal (EPR23495-268)
  • immunohistochemistry - paraffin section; human; loading ...; fig 6a
  • chromatin immunoprecipitation; human; loading ...; fig 4k
  • western blot; human; loading ...; fig 4h
Abcam Ep300 antibody (Abcam, ab275378) was used in immunohistochemistry - paraffin section on human samples (fig 6a), in chromatin immunoprecipitation on human samples (fig 4k) and in western blot on human samples (fig 4h). Clin Transl Med (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 6a
Invitrogen Ep300 antibody (ThermoFisher, PA5-64531) was used in western blot on human samples at 1:1000 (fig 6a). Nat Commun (2019) ncbi
mouse monoclonal (RW105)
  • chromatin immunoprecipitation; human; loading ...; fig 5e
In order to assess the effect of TNF-alpha inhibitors on monocyte chemoattractant protein-1, Invitrogen Ep300 antibody (Thermo Fisher, MA1-16622) was used in chromatin immunoprecipitation on human samples (fig 5e). Mol Immunol (2017) ncbi
mouse monoclonal (NM-11)
  • flow cytometry; mouse; fig 5
  • immunocytochemistry; mouse; fig 5
In order to study the role of local BMP-SMAD1 signaling as it increases LIF receptor-dependent STAT3 responsiveness and pluripotent stem cell conversion frequencey in primed-to-naive mouse, Invitrogen Ep300 antibody (Life Technologies, 33-7600) was used in flow cytometry on mouse samples (fig 5) and in immunocytochemistry on mouse samples (fig 5). Stem Cell Reports (2014) ncbi
mouse monoclonal (RW105)
  • western blot; human
In order to study mechanisms of microtubule hyperacetylation, Invitrogen Ep300 antibody (Pierce Biotechnology, MA1-16622) was used in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (NM-11)
  • western blot; African green monkey; fig s4
In order to elucidate how SUMO controls synergy, Invitrogen Ep300 antibody (Zymed, 33-7600) was used in western blot on African green monkey samples (fig s4). Nucleic Acids Res (2010) ncbi
mouse monoclonal (NM-11)
  • western blot; human
In order to identify Mi-2alpha as an interaction partner of human c-Myb, Invitrogen Ep300 antibody (Zymed, 33-7600) was used in western blot on human samples . J Biol Chem (2007) ncbi
Articles Reviewed
  1. Leng S, Zhang X, Wang S, Qin J, Liu Q, Liu A, et al. Ion channel Piezo1 activation promotes aerobic glycolysis in macrophages. Front Immunol. 2022;13:976482 pubmed publisher
  2. Zhang C, Lu X, Huang J, He H, Chen L, Liu Y, et al. Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma. Clin Transl Med. 2021;11:e328 pubmed publisher
  3. Du A, Li L, Jiao Z, Zhu G, Peng T, Li H. Protein expression pattern of calcium-responsive transactivator in early postnatal and adult testes. Histochem Cell Biol. 2021;155:491-502 pubmed publisher
  4. Wilson M, Reske J, Holladay J, Neupane S, Ngo J, Cuthrell N, et al. ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. Cell Rep. 2020;33:108366 pubmed publisher
  5. Miyazaki T, Zhao Z, Ichihara Y, Yoshino D, Imamura T, Sawada K, et al. Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity. Sci Adv. 2019;5:eaau7802 pubmed publisher
  6. Rubio K, Singh I, Dobersch S, Sarvari P, Günther S, Cordero J, et al. Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. Nat Commun. 2019;10:2229 pubmed publisher
  7. Lee J, Chang J, Dominguez A, Lee H, Nam S, Chang J, et al. YAP-independent mechanotransduction drives breast cancer progression. Nat Commun. 2019;10:1848 pubmed publisher
  8. Bao J, Rousseaux S, Shen J, Lin K, Lu Y, Bedford M. The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis. Nucleic Acids Res. 2018;46:4327-4343 pubmed publisher
  9. Xiao X, Fan Y, Li J, Zhang X, Lou X, Dou Y, et al. Guidance of super-enhancers in regulation of IL-9 induction and airway inflammation. J Exp Med. 2018;215:559-574 pubmed publisher
  10. Wu Y, Zhang Z, Cenciarini M, Proietti C, Amasino M, Hong T, et al. Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis. Cancer Res. 2018;78:671-684 pubmed publisher
  11. Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed publisher
  12. Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed publisher
  13. Formisano L, Guida N, Valsecchi V, Cantile M, Cuomo O, Vinciguerra A, et al. Sp3/REST/HDAC1/HDAC2 Complex Represses and Sp1/HIF-1/p300 Complex Activates ncx1 Gene Transcription, in Brain Ischemia and in Ischemic Brain Preconditioning, by Epigenetic Mechanism. J Neurosci. 2015;35:7332-48 pubmed publisher
  14. Onishi K, Tonge P, Nagy A, Zandstra P. Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency. Stem Cell Reports. 2014;3:156-68 pubmed publisher
  15. Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed publisher
  16. Wehmeyer L, Du Toit A, Lang D, Hapgood J. Lipid raft- and protein kinase C-mediated synergism between glucocorticoid- and gonadotropin-releasing hormone signaling results in decreased cell proliferation. J Biol Chem. 2014;289:10235-51 pubmed publisher
  17. Ogiwara H, Kohno T. CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes. PLoS ONE. 2012;7:e52810 pubmed publisher
  18. Zhu X, Huang C, Li Q, Guo Q, Wang Y, He X, et al. Temporal distribution of p300/CBP immunoreactivity in the adult rat spinal dorsal horn following chronic constriction injury (CCI). Cell Mol Neurobiol. 2013;33:197-204 pubmed publisher
  19. Molvaersmyr A, Saether T, Gilfillan S, Lorenzo P, Kvaløy H, Matre V, et al. A SUMO-regulated activation function controls synergy of c-Myb through a repressor-activator switch leading to differential p300 recruitment. Nucleic Acids Res. 2010;38:4970-84 pubmed publisher
  20. Saether T, Berge T, Ledsaak M, Matre V, Alm Kristiansen A, Dahle O, et al. The chromatin remodeling factor Mi-2alpha acts as a novel co-activator for human c-Myb. J Biol Chem. 2007;282:13994-4005 pubmed