This is a Validated Antibody Database (VAD) review about mouse Ell2, based on 4 published articles (read how Labome selects the articles), using Ell2 antibody in all methods. It is aimed to help Labome visitors find the most suited Ell2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ell2 synonym: RNA polymerase II elongation factor ELL2; ELL-related RNA polymerase II, elongation factor; eleven-nineteen lysine-rich leukemia gene 2

Bethyl
rabbit polyclonal
  • western blot; human; loading ...; fig s2
In order to evaluate the physical and functional interaction of elongation factor, RNA polymerase II, 2 with retinoblastoma in prostate cancer, Bethyl Ell2 antibody (Bethyl, A302-505A) was used in western blot on human samples (fig s2). Neoplasia (2017) ncbi
rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 6a
In order to describe a crystal structure of the human ELL2 C-terminal domain bound to its 50-residue binding site on AFF4, Bethyl Ell2 antibody (Bethyl, A302-505A) was used in immunoprecipitation on human samples (fig 6a). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; human; fig 1
Bethyl Ell2 antibody (Bethyl Laboratories, A302-505A) was used in western blot on human samples (fig 1). Nucleic Acids Res (2015) ncbi
rabbit polyclonal
  • ChIP-Seq; human; fig 4
Bethyl Ell2 antibody (Bethyl, A302-505A) was used in ChIP-Seq on human samples (fig 4). Nat Genet (2015) ncbi
Articles Reviewed
  1. Qiu X, Pascal L, Song Q, Zang Y, Ai J, O Malley K, et al. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion. Neoplasia. 2017;19:207-215 pubmed publisher
  2. Qi S, Li Z, Schulze Gahmen U, Stjepanovic G, Zhou Q, Hurley J. Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription. Nat Commun. 2017;8:14076 pubmed publisher
  3. Lu H, Li Z, Zhang W, Schulze Gahmen U, Xue Y, Zhou Q. Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription. Nucleic Acids Res. 2015;43:5868-79 pubmed publisher
  4. Izumi K, Nakato R, Zhang Z, Edmondson A, Noon S, Dulik M, et al. Germline gain-of-function mutations in AFF4 cause a developmental syndrome functionally linking the super elongation complex and cohesin. Nat Genet. 2015;47:338-44 pubmed publisher