This is a Validated Antibody Database (VAD) review about mouse Eif4e1b, based on 31 published articles (read how Labome selects the articles), using Eif4e1b antibody in all methods. It is aimed to help Labome visitors find the most suited Eif4e1b antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Eif4e1b synonym: Eif4eloo; Gm273; eukaryotic translation initiation factor 4E type 1B

Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s3d
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9741) was used in western blot on mouse samples at 1:1000 (fig s3d). Science (2019) ncbi
rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 1b
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in western blot on human samples at 1:2000 (fig 1b). Int J Biol Sci (2019) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in western blot on human samples (fig 6c). Oncogene (2019) ncbi
rabbit polyclonal
  • other; human; loading ...; fig 4c
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; fig s5a
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in western blot on human samples (fig s5a). Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; fig s5a
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in western blot on human samples (fig s5a). Cell (2018) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s5p
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in western blot on human samples (fig s5p). Nature (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1e
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in western blot on human samples (fig 1e). J Clin Invest (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 5b
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9741) was used in western blot on mouse samples (fig 5b). Cancer Res (2017) ncbi
rabbit polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology Eif4e1b antibody (CST, 9742) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig s1c
In order to analyze if the conserved DEAD-box protein DDX6 is commonly present in the nuclei of human-derived cells, Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in western blot on human samples (fig s1c). Sci Rep (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9742) was used in western blot on human samples . Cell Syst (2017) ncbi
rabbit polyclonal
  • western blot; rat; loading ...; fig 8a
In order to link eIF4B and eIF4E alterations to the induction of stress granules in regions of the brain vulnerable to death after ischemia-reperfusion injury, Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in western blot on rat samples (fig 8a). J Biol Chem (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig st1
In order to identify and characterize alterations in signal transduction that occur during the development Lapatinib resistance, Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1s1
Cell Signaling Technology Eif4e1b antibody (CST, 9742) was used in western blot on human samples (fig 1s1). elife (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 1
In order to analyze induction of the regression of NF1-mutant cancers by cotargeting MNK and MEK kinases, Cell Signaling Technology Eif4e1b antibody (Cell signaling, 9742) was used in western blot on human samples (fig 1). J Clin Invest (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741S) was used in western blot on human samples (fig 4). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; pig; 1:4000
In order to test if prolonged enteral leucine supplementation improves lean growth in neonatal pigs fed a restricted protein diet, Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9742) was used in western blot on pig samples at 1:4000. Am J Physiol Endocrinol Metab (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in western blot on human samples (fig 2). Nat Immunol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in western blot on human samples (fig 2). Nat Immunol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 2.e
Cell Signaling Technology Eif4e1b antibody (CellSignaling, 9741) was used in western blot on human samples at 1:500 (fig 2.e). Nat Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; 1:500; fig 2.e
Cell Signaling Technology Eif4e1b antibody (CellSignaling, 9742) was used in western blot on human samples at 1:500 (fig 2.e). Nat Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Eif4e1b antibody (CST, 9741) was used in western blot on human samples (fig 4). Oncotarget (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1c
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in immunohistochemistry on human samples (fig 2c) and in western blot on mouse samples (fig 1c). EMBO Rep (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1c
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in immunohistochemistry on human samples (fig 2c) and in western blot on mouse samples (fig 1c). EMBO Rep (2015) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Tech, 9742) was used in western blot on mouse samples at 1:1000 (fig 6). PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunoprecipitation; human; fig 4
  • immunocytochemistry; human; fig s5
  • western blot; human; 1:1000; fig 7
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in immunoprecipitation on human samples (fig 4), in immunocytochemistry on human samples (fig s5), in western blot on human samples at 1:1000 (fig 7) and in western blot on mouse samples at 1:1000 (fig 3). PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; Aplysia; fig 5
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9741) was used in immunocytochemistry on Aplysia samples (fig 5). elife (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; Aplysia; fig 5s1
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9742) was used in immunocytochemistry on Aplysia samples (fig 5s1). elife (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742) was used in western blot on human samples (fig 4). Cancer Lett (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 7
  • western blot; human; fig 4
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9741) was used in immunohistochemistry - paraffin section on human samples (fig 7) and in western blot on human samples (fig 4). Cancer Lett (2015) ncbi
rabbit polyclonal
  • western blot; pig; 1:500
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9741) was used in western blot on pig samples at 1:500. Amino Acids (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000
In order to investigate the involvement of matrix metalloproteinase 9 in the phenotype of fragile X syndrome, Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9741) was used in western blot on mouse samples at 1:1000. J Neurosci (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9742) was used in western blot on human samples . Mol Cell Biol (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology Eif4e1b antibody (Cell Signaling Technology, 9741) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • western blot; human
Cell Signaling Technology Eif4e1b antibody (Cell Signaling, 9742S) was used in western blot on human samples . Mol Cancer Ther (2013) ncbi
Articles Reviewed
  1. Zhu P, Khatiwada S, Cui Y, Reineke L, Dooling S, Kim J, et al. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science. 2019;366:843-849 pubmed publisher
  2. Wang H, Huang F, Zhang Z, Wang P, Luo Y, Li H, et al. Feedback Activation of SGK3 and AKT Contributes to Rapamycin Resistance by Reactivating mTORC1/4EBP1 Axis via TSC2 in Breast Cancer. Int J Biol Sci. 2019;15:929-941 pubmed publisher
  3. Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al. Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed publisher
  4. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  5. Chung H, Calis J, Wu X, Sun T, Yu Y, Sarbanes S, et al. Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown. Cell. 2018;172:811-824.e14 pubmed publisher
  6. Schafer S, Viswanathan S, Widjaja A, Lim W, Moreno Moral A, Delaughter D, et al. IL-11 is a crucial determinant of cardiovascular fibrosis. Nature. 2017;552:110-115 pubmed publisher
  7. Zhan Y, Guo J, Yang W, Goncalves C, Rzymski T, Dreas A, et al. MNK1/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma. J Clin Invest. 2017;127:4179-4192 pubmed publisher
  8. Hsu J, Hubbell Engler B, Adelmant G, Huang J, Joyce C, Vazquez F, et al. PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer. Cancer Res. 2017;77:4613-4625 pubmed publisher
  9. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  10. Huang J, Ku W, Chen Y, Chang Y, Chu C. Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6. Sci Rep. 2017;7:42853 pubmed publisher
  11. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  12. Ayuso M, Martínez Alonso E, Regidor I, Alcazar A. Stress Granule Induction after Brain Ischemia Is Independent of Eukaryotic Translation Initiation Factor (eIF) 2? Phosphorylation and Is Correlated with a Decrease in eIF4B and eIF4E Proteins. J Biol Chem. 2016;291:27252-27264 pubmed publisher
  13. Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  14. Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed publisher
  15. Mounir Z, Korn J, Westerling T, Lin F, Kirby C, Schirle M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor. elife. 2016;5: pubmed publisher
  16. Lock R, Ingraham R, Maertens O, Miller A, Weledji N, Legius E, et al. Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers. J Clin Invest. 2016;126:2181-90 pubmed publisher
  17. Lyabin D, Ovchinnikov L. Selective regulation of YB-1 mRNA translation by the mTOR signaling pathway is not mediated by 4E-binding protein. Sci Rep. 2016;6:22502 pubmed publisher
  18. Columbus D, Steinhoff Wagner J, Suryawan A, Nguyen H, Hernandez Garcia A, Fiorotto M, et al. Impact of prolonged leucine supplementation on protein synthesis and lean growth in neonatal pigs. Am J Physiol Endocrinol Metab. 2015;309:E601-10 pubmed publisher
  19. Su X, Yu Y, Zhong Y, Giannopoulou E, Hu X, Liu H, et al. Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation. Nat Immunol. 2015;16:838-849 pubmed publisher
  20. Laberge R, Sun Y, Orjalo A, Patil C, Freund A, Zhou L, et al. MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nat Cell Biol. 2015;17:1049-61 pubmed publisher
  21. Wang J, Ma L, Tang X, Zhang X, Qiao Y, Shi Y, et al. Doxorubicin induces apoptosis by targeting Madcam1 and AKT and inhibiting protein translation initiation in hepatocellular carcinoma cells. Oncotarget. 2015;6:24075-91 pubmed
  22. Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
  23. Sato M, Matsubara T, Adachi J, Hashimoto Y, Fukamizu K, Kishida M, et al. Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model. PLoS ONE. 2015;10:e0126483 pubmed publisher
  24. Martínez A, Sesé M, Losa J, Robichaud N, Sonenberg N, Aasen T, et al. Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. PLoS ONE. 2015;10:e0123352 pubmed publisher
  25. Kim S, Martin K. Neuron-wide RNA transport combines with netrin-mediated local translation to spatially regulate the synaptic proteome. elife. 2015;4: pubmed publisher
  26. Chen Y, Wei M, Wang C, Lee H, Pan S, Gao M, et al. Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer. Cancer Lett. 2015;357:582-90 pubmed publisher
  27. Zhang S, Ren M, Zeng X, He P, Ma X, Qiao S. Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways. Amino Acids. 2014;46:2633-42 pubmed publisher
  28. Sidhu H, Dansie L, Hickmott P, Ethell D, Ethell I. Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile X syndrome in a mouse model. J Neurosci. 2014;34:9867-79 pubmed publisher
  29. Cen B, Xiong Y, Song J, Mahajan S, DuPont R, McEachern K, et al. The Pim-1 protein kinase is an important regulator of MET receptor tyrosine kinase levels and signaling. Mol Cell Biol. 2014;34:2517-32 pubmed publisher
  30. Bian Z, Liao H, Zhang Y, Wu Q, Zhou H, Yang Z, et al. Never in mitosis gene A related kinase-6 attenuates pressure overload-induced activation of the protein kinase B pathway and cardiac hypertrophy. PLoS ONE. 2014;9:e96095 pubmed publisher
  31. Sreevalsan S, Safe S. The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells. Mol Cancer Ther. 2013;12:2483-93 pubmed publisher