This is a Validated Antibody Database (VAD) review about mouse Eif2ak2, based on 13 published articles (read how Labome selects the articles), using Eif2ak2 antibody in all methods. It is aimed to help Labome visitors find the most suited Eif2ak2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Eif2ak2 synonym: 2310047A08Rik; 4732414G15Rik; AI467567; AI747578; Pkr; Prkr; Tik

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (B-10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, SC-6282) was used in western blot knockout validation on mouse samples (fig 2b). PLoS Biol (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-10)
  • western blot knockout validation; mouse; fig 5c
Santa Cruz Biotechnology Eif2ak2 antibody (Santa, sc-6282) was used in western blot knockout validation on mouse samples (fig 5c). Blood (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-10)
  • western blot knockout validation; mouse; loading ...; fig 2b
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, SC-6282) was used in western blot knockout validation on mouse samples (fig 2b). PLoS Biol (2021) ncbi
mouse monoclonal (B-10)
  • western blot; mouse; loading ...; fig 1b
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on mouse samples (fig 1b). elife (2020) ncbi
mouse monoclonal (B-10)
  • western blot; mouse; loading ...; fig 5h
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on mouse samples (fig 5h). J Clin Invest (2020) ncbi
mouse monoclonal (B-10)
  • western blot; rat; loading ...; fig 7a
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz Biotechnology, sc-6282) was used in western blot on rat samples (fig 7a). Biomed Pharmacother (2019) ncbi
mouse monoclonal (B-10)
  • western blot; mouse; 1:200; loading ...; fig 2a
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on mouse samples at 1:200 (fig 2a). MBio (2019) ncbi
mouse monoclonal (B-10)
  • western blot; mouse; loading ...; fig 6d, s13c
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on mouse samples (fig 6d, s13c). J Clin Invest (2019) ncbi
mouse monoclonal (B-10)
  • western blot; human; fig 5
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on human samples (fig 5). PLoS ONE (2016) ncbi
mouse monoclonal (B-10)
  • western blot; human; fig 4
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on human samples (fig 4). PLoS Pathog (2016) ncbi
mouse monoclonal (B-10)
  • western blot; mouse; 1:1000; fig 5
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
mouse monoclonal (B-10)
  • western blot; human; fig 4
  • western blot; mouse; fig 4
Santa Cruz Biotechnology Eif2ak2 antibody (Santa Cruz, sc-6282) was used in western blot on human samples (fig 4) and in western blot on mouse samples (fig 4). Mol Cell Biol (2015) ncbi
mouse monoclonal (B-10)
  • western blot knockout validation; mouse; fig 5c
Santa Cruz Biotechnology Eif2ak2 antibody (Santa, sc-6282) was used in western blot knockout validation on mouse samples (fig 5c). Blood (2013) ncbi
Abcam
domestic rabbit monoclonal (EPR19374)
  • western blot; mouse; loading ...; fig 7e
Abcam Eif2ak2 antibody (Abcam, EPR19374) was used in western blot on mouse samples (fig 7e). Nature (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; rat; fig 3
In order to determine regulation of global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha by the small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives, Invitrogen Eif2ak2 antibody (Life Technologies, 44-668G) was used in western blot on rat samples (fig 3). Cell Stress Chaperones (2016) ncbi
Articles Reviewed
  1. Lu Y, Kavianpour S, Zhang T, Zhang X, Nguyen D, Thombre R, et al. MARK2 phosphorylates eIF2α in response to proteotoxic stress. PLoS Biol. 2021;19:e3001096 pubmed publisher
  2. Farabaugh K, Krokowski D, Guan B, Gao Z, Gao X, Wu J, et al. PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation. elife. 2020;9: pubmed publisher
  3. Theivanthiran B, Evans K, Devito N, Plebanek M, Sturdivant M, Wachsmuth L, et al. A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy. J Clin Invest. 2020;130:2570-2586 pubmed publisher
  4. Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed publisher
  5. Goodman D, Pretto C, Krepostman T, Carnahan K, Spindler K. Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR). MBio. 2019;10: pubmed publisher
  6. Ishizuka J, Manguso R, Cheruiyot C, Bi K, Panda A, Iracheta Vellve A, et al. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. Nature. 2019;565:43-48 pubmed publisher
  7. Hato T, Maier B, Syed F, Myslinski J, Zollman A, Plotkin Z, et al. Bacterial sepsis triggers an antiviral response that causes translation shutdown. J Clin Invest. 2019;129:296-309 pubmed publisher
  8. Ren S, Wang J, Chen T, Li H, Wan Y, Peng N, et al. Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms. PLoS ONE. 2016;11:e0152721 pubmed publisher
  9. Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
  10. Oh S, Onomoto K, Wakimoto M, Onoguchi K, Ishidate F, Fujiwara T, et al. Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules. PLoS Pathog. 2016;12:e1005444 pubmed publisher
  11. Lancaster G, Kammoun H, Kraakman M, Kowalski G, Bruce C, Febbraio M. PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. Nat Commun. 2016;7:10626 pubmed publisher
  12. So J, Cho S, Min S, Kimball S, Lee A. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis. Mol Cell Biol. 2015;35:2761-70 pubmed publisher
  13. Liu X, Bennett R, Cheng X, Byrne M, Reinhard M, May W. PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells. Blood. 2013;121:3364-74 pubmed publisher