This is a Validated Antibody Database (VAD) review about mouse Dyrk1a, based on 10 published articles (read how Labome selects the articles), using Dyrk1a antibody in all methods. It is aimed to help Labome visitors find the most suited Dyrk1a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Dyrk1a synonym: 2310043O08Rik; D16Ertd272e; D16Ertd493e; Dyrk; Gm10783; Mnbh; Mp86; mmb

Abnova
mouse monoclonal (7D10)
  • western blot; Human immunodeficiency virus 1; loading ...; fig s1k
Abnova Dyrk1a antibody (Abnova, H00001859-M01) was used in western blot on Human immunodeficiency virus 1 samples (fig s1k). MBio (2018) ncbi
mouse monoclonal (7D10)
  • immunoprecipitation; human; fig 4
Abnova Dyrk1a antibody (Abnova, 7D10) was used in immunoprecipitation on human samples (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (7D10)
  • western blot; human; 1:200; fig 1
Abnova Dyrk1a antibody (Abnova, H00001859-M01) was used in western blot on human samples at 1:200 (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (7D10)
  • immunoprecipitation; mouse; 10 ug
  • western blot; mouse
In order to test if DYRK1A phosphorylation affects the density and activity of NMDARs, Abnova Dyrk1a antibody (Abnova Corporation, H00001859-M01) was used in immunoprecipitation on mouse samples at 10 ug and in western blot on mouse samples . Front Cell Neurosci (2014) ncbi
mouse monoclonal (7D10)
  • western blot; mouse; 1:250
Abnova Dyrk1a antibody (Abnova Corporation, H00001859-M01) was used in western blot on mouse samples at 1:250. Transl Psychiatry (2014) ncbi
MilliporeSigma
mouse monoclonal (7D10)
  • immunocytochemistry; human; loading ...; fig 3c, 3e
  • western blot; human; loading ...; fig 1a, 1e
  • western blot; mouse; loading ...; fig 4f
MilliporeSigma Dyrk1a antibody (Sigma-Aldrich, WH0001859M1) was used in immunocytochemistry on human samples (fig 3c, 3e), in western blot on human samples (fig 1a, 1e) and in western blot on mouse samples (fig 4f). J Biol Chem (2019) ncbi
mouse monoclonal (7D10)
  • western blot; human; loading ...; fig 1a
In order to find DYRK1A increases NFATc1/alphaA protein levels and subsequent transcriptional activity, MilliporeSigma Dyrk1a antibody (Sigma-Aldrich, WH001859M1) was used in western blot on human samples (fig 1a). PLoS ONE (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D30C10)
  • western blot; human; loading ...; fig 4 - s1d
Cell Signaling Technology Dyrk1a antibody (Cell Signalling Technologies, 8765) was used in western blot on human samples (fig 4 - s1d). elife (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:3000; fig 2
In order to study kinase DYRK1A selective inhibition by targeting its folding process, Cell Signaling Technology Dyrk1a antibody (Cell Signaling Technology, 2771S) was used in western blot on human samples at 1:3000 (fig 2). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; human; fig 2
  • western blot; human; 1:1000; fig 3
In order to report the contribution of DYRK1A and DYRK1B in cancer stem cells, Cell Signaling Technology Dyrk1a antibody (Cell Signaling Technology, 2771) was used in immunoprecipitation on human samples (fig 2) and in western blot on human samples at 1:1000 (fig 3). Nature (2016) ncbi
Articles Reviewed
  1. Tian S, Jia W, Lu M, Zhao J, Sun X. Dual-specificity tyrosine phosphorylation-regulated kinase 1A ameliorates insulin resistance in neurons by up-regulating IRS-1 expression. J Biol Chem. 2019;: pubmed publisher
  2. Kyei G, Meng S, Ramani R, Niu A, Lagisetti C, Webb T, et al. Splicing Factor 3B Subunit 1 Interacts with HIV Tat and Plays a Role in Viral Transcription and Reactivation from Latency. MBio. 2018;9: pubmed publisher
  3. Bellmaine S, Ovchinnikov D, Manallack D, Cuddy C, Elefanty A, Stanley E, et al. Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells. elife. 2017;6: pubmed publisher
  4. Liu H, Wang K, Chen S, Sun Q, Zhang Y, Chen L, et al. NFATc1 phosphorylation by DYRK1A increases its protein stability. PLoS ONE. 2017;12:e0172985 pubmed publisher
  5. Glenewinkel F, Cohen M, King C, Kaspar S, Bamberg Lemper S, Mymryk J, et al. The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2. Sci Rep. 2016;6:28241 pubmed publisher
  6. Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher
  7. Lee S, Frattini V, Bansal M, Castano A, Sherman D, Hutchinson K, et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016;529:172-7 pubmed publisher
  8. Booiman T, Loukachov V, van Dort K, van t Wout A, Kootstra N. DYRK1A Controls HIV-1 Replication at a Transcriptional Level in an NFAT Dependent Manner. PLoS ONE. 2015;10:e0144229 pubmed publisher
  9. Grau C, Arató K, Fernández Fernández J, Valderrama A, Sindreu C, Fillat C, et al. DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors. Front Cell Neurosci. 2014;8:331 pubmed publisher
  10. Janel N, Sarazin M, Corlier F, Corne H, de Souza L, Hamelin L, et al. Plasma DYRK1A as a novel risk factor for Alzheimer's disease. Transl Psychiatry. 2014;4:e425 pubmed publisher