This is a Validated Antibody Database (VAD) review about mouse Dfna5l, based on 14 published articles (read how Labome selects the articles), using Dfna5l antibody in all methods. It is aimed to help Labome visitors find the most suited Dfna5l antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Dfna5l synonym: 1810036L03Rik; AW558049; DF5L; Dfna5l; Gsdmdc1; M2-4

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (H-11)
  • western blot knockout validation; mouse; loading ...; fig 1k
Santa Cruz Biotechnology Dfna5l antibody (Santa Cruz, H-11) was used in western blot knockout validation on mouse samples (fig 1k). Nat Commun (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-7)
  • western blot knockout validation; mouse; 1:1000; fig s8
In order to study a signal amplification mechanism for inflammasomes through ASC filament formation, Santa Cruz Biotechnology Dfna5l antibody (Santa Cruz, A-7) was used in western blot knockout validation on mouse samples at 1:1000 (fig s8). Nat Commun (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5b
  • western blot knockout validation; human; fig 5c
Novus Biologicals Dfna5l antibody (Novus Biologicals, NBP2-33422) was used in western blot on mouse samples (fig 5b) and in western blot knockout validation on human samples (fig 5c). Nat Chem Biol (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-7)
  • western blot; mouse; loading ...; fig 1d
Santa Cruz Biotechnology Dfna5l antibody (Santa, Sc-393656) was used in western blot on mouse samples (fig 1d). Sci Adv (2019) ncbi
mouse monoclonal (A-7)
  • western blot; mouse; loading ...; fig 8c
Santa Cruz Biotechnology Dfna5l antibody (Santa, sc-393656) was used in western blot on mouse samples (fig 8c). J Exp Med (2019) ncbi
mouse monoclonal (A-7)
  • immunocytochemistry; mouse; loading ...; fig 1d
Santa Cruz Biotechnology Dfna5l antibody (SantaCruz, sc-393656) was used in immunocytochemistry on mouse samples (fig 1d). EBioMedicine (2018) ncbi
mouse monoclonal (H-11)
  • western blot knockout validation; mouse; loading ...; fig 1k
Santa Cruz Biotechnology Dfna5l antibody (Santa Cruz, H-11) was used in western blot knockout validation on mouse samples (fig 1k). Nat Commun (2018) ncbi
mouse monoclonal (A-7)
  • western blot; human; fig 6c
Santa Cruz Biotechnology Dfna5l antibody (Santa, sc-393656) was used in western blot on human samples (fig 6c). J Clin Invest (2017) ncbi
mouse monoclonal (A-7)
  • western blot; human; loading ...; fig 2d
Santa Cruz Biotechnology Dfna5l antibody (Santa Cruz, sc-393656) was used in western blot on human samples (fig 2d). Nat Commun (2017) ncbi
mouse monoclonal (A-7)
  • immunoprecipitation; mouse; fig 3B
  • western blot; mouse; 0.4 ug/ml; fig 3B
Santa Cruz Biotechnology Dfna5l antibody (Santa Cruz, A-7) was used in immunoprecipitation on mouse samples (fig 3B) and in western blot on mouse samples at 0.4 ug/ml (fig 3B). J Immunol (2016) ncbi
mouse monoclonal (A-7)
  • western blot knockout validation; mouse; 1:1000; fig s8
In order to study a signal amplification mechanism for inflammasomes through ASC filament formation, Santa Cruz Biotechnology Dfna5l antibody (Santa Cruz, A-7) was used in western blot knockout validation on mouse samples at 1:1000 (fig s8). Nat Commun (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR19828)
  • western blot; mouse; 1:500; loading ...; fig 1j, 5e, 6d
Abcam Dfna5l antibody (Abcam, ab209845) was used in western blot on mouse samples at 1:500 (fig 1j, 5e, 6d). Nat Commun (2018) ncbi
domestic rabbit monoclonal (EPR19828)
  • western blot; mouse; 1:1000; loading ...; fig 1d
Abcam Dfna5l antibody (Abcam, ab209845) was used in western blot on mouse samples at 1:1000 (fig 1d). J Cell Biol (2018) ncbi
domestic rabbit monoclonal (EPR19828)
  • western blot; mouse; loading ...; fig 7f
Abcam Dfna5l antibody (Abcam, ab209845) was used in western blot on mouse samples (fig 7f). Front Immunol (2018) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3b
Novus Biologicals Dfna5l antibody (Novus Biologicals, NBP2-33422) was used in western blot on human samples (fig 3b). Nat Med (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5b
  • western blot knockout validation; human; fig 5c
Novus Biologicals Dfna5l antibody (Novus Biologicals, NBP2-33422) was used in western blot on mouse samples (fig 5b) and in western blot knockout validation on human samples (fig 5c). Nat Chem Biol (2017) ncbi
Cell Signaling Technology
domestic rabbit (L60)
  • western blot; human; 1:1000; loading ...; fig 2i
Cell Signaling Technology Dfna5l antibody (Cell Signaling, 93709) was used in western blot on human samples at 1:1000 (fig 2i). Nat Immunol (2020) ncbi
Articles Reviewed
  1. Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, et al. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41 pubmed publisher
  2. Chen R, Zeng L, Zhu S, Liu J, Zeh H, Kroemer G, et al. cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis. Sci Adv. 2019;5:eaav5562 pubmed publisher
  3. Faliti C, Gualtierotti R, Rottoli E, Gerosa M, Perruzza L, Romagnani A, et al. P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus. J Exp Med. 2019;216:317-336 pubmed publisher
  4. Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed publisher
  5. de la Roche M, Hamilton C, Mortensen R, Jeyaprakash A, Ghosh S, Anand P. Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. J Cell Biol. 2018;217:3560-3576 pubmed publisher
  6. Johnson D, Taabazuing C, Okondo M, Chui A, Rao S, Brown F, et al. DPP8/DPP9 inhibitor-induced pyroptosis for treatment of acute myeloid leukemia. Nat Med. 2018;24:1151-1156 pubmed publisher
  7. Qu W, Wang Y, Wu Y, Liu Y, Chen K, Liu X, et al. Triggering Receptors Expressed on Myeloid Cells 2 Promotes Corneal Resistance Against Pseudomonas aeruginosa by Inhibiting Caspase-1-Dependent Pyroptosis. Front Immunol. 2018;9:1121 pubmed publisher
  8. Chen Y, Qin X, An Q, Yi J, Feng F, Yin D, et al. Mesenchymal Stromal Cells Directly Promote Inflammation by Canonical NLRP3 and Non-canonical Caspase-11 Inflammasomes. EBioMedicine. 2018;32:31-42 pubmed publisher
  9. Chu L, Indramohan M, Ratsimandresy R, Gangopadhyay A, Morris E, Monack D, et al. The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages. Nat Commun. 2018;9:996 pubmed publisher
  10. Cheng K, Xiong S, Ye Z, Hong Z, Di A, Tsang K, et al. Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury. J Clin Invest. 2017;127:4124-4135 pubmed publisher
  11. Rogers C, Fernandes Alnemri T, Mayes L, Alnemri D, Cingolani G, Alnemri E. Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. Nat Commun. 2017;8:14128 pubmed publisher
  12. Okondo M, Johnson D, Sridharan R, Go E, Chui A, Wang M, et al. DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis. Nat Chem Biol. 2017;13:46-53 pubmed publisher
  13. Russo H, Rathkey J, Boyd Tressler A, Katsnelson M, Abbott D, Dubyak G. Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides. J Immunol. 2016;197:1353-67 pubmed publisher
  14. Dick M, Sborgi L, Rühl S, Hiller S, Broz P. ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nat Commun. 2016;7:11929 pubmed publisher