This is a Validated Antibody Database (VAD) review about mouse Ddb1, based on 18 published articles (read how Labome selects the articles), using Ddb1 antibody in all methods. It is aimed to help Labome visitors find the most suited Ddb1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ddb1 synonym: 127kDa; AA408517; p127-Ddb1

Santa Cruz Biotechnology
mouse monoclonal (E-11)
  • western blot; human; loading ...; fig 1d, 1e, s2
Santa Cruz Biotechnology Ddb1 antibody (Santa Cruz, sc-376860) was used in western blot on human samples (fig 1d, 1e, s2). Int J Biol Sci (2022) ncbi
mouse monoclonal (E-11)
  • western blot; human; 1:1000; loading ...; fig 5c
Santa Cruz Biotechnology Ddb1 antibody (SantaCruz, sc-376860) was used in western blot on human samples at 1:1000 (fig 5c). elife (2020) ncbi
mouse monoclonal (B-1)
  • western blot; mouse; loading ...; fig 3d
In order to use knockout mice to determine the role of cereblon in T cells, Santa Cruz Biotechnology Ddb1 antibody (Santa Cruz, B-1) was used in western blot on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (8)
  • western blot; human; 1:500; fig 4
Santa Cruz Biotechnology Ddb1 antibody (Santa Cruz, sc-136180) was used in western blot on human samples at 1:500 (fig 4). FASEB J (2016) ncbi
Invitrogen
mouse monoclonal (2B12D1)
  • western blot; human; loading ...; fig 3b
Invitrogen Ddb1 antibody (Invitrogen, 37-6200) was used in western blot on human samples (fig 3b). Sci Adv (2019) ncbi
mouse monoclonal (2B12D1)
  • western blot; human; loading ...; fig 5a
In order to show that the Abl-DDB1-DDA1 axis reduces CRL4 substrate ubiquitination, Invitrogen Ddb1 antibody (Invitrogen, 37-6200) was used in western blot on human samples (fig 5a). J Biol Chem (2017) ncbi
mouse monoclonal (2B12D1)
  • western blot; human; fig 4
In order to analyze the divergent interactions with UNG2 and HLTF DNA repair proteins by HIV-1 and HIV-2, Invitrogen Ddb1 antibody (Invitrogen, 37-6200) was used in western blot on human samples (fig 4). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (ZD001)
  • western blot; human; 1:1000; fig 3
In order to study UVA response and nucleotide excision repair deficiency in melanoma, Invitrogen Ddb1 antibody (Invitrogen, ZD001) was used in western blot on human samples at 1:1000 (fig 3). Exp Hematol Oncol (2015) ncbi
mouse monoclonal (2B12D1)
  • western blot; human; fig 2
In order to investigate how ubiquitination of BK channels contributes to epilepsy, Invitrogen Ddb1 antibody (Invitrogen, 37-6200) was used in western blot on human samples (fig 2). Nat Commun (2014) ncbi
mouse monoclonal (2B12D1)
  • western blot; human; fig 1a
In order to suggest that lentiviral Vpx usurps VprBP-associated Cullin 4 ubiquitin ligase to allow for efficient reverse transcription, Invitrogen Ddb1 antibody (Zymed/Invitrogen, 37-6200) was used in western blot on human samples (fig 1a). PLoS Pathog (2008) ncbi
Abcam
domestic rabbit monoclonal (EPR6089)
  • western blot; human; loading ...; fig 7s1a
Abcam Ddb1 antibody (Abcam, ab109027) was used in western blot on human samples (fig 7s1a). elife (2019) ncbi
domestic rabbit monoclonal (EPR6089)
  • immunoprecipitation; human; loading ...; fig 4a
Abcam Ddb1 antibody (AbCam, ab109027) was used in immunoprecipitation on human samples (fig 4a). elife (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:100; loading ...; fig s8c
Abcam Ddb1 antibody (Abcam, ab97522) was used in immunohistochemistry on human samples at 1:100 (fig s8c). Nat Commun (2018) ncbi
domestic rabbit monoclonal (EPR6089)
  • western blot; human; 1:10,000; loading ...; fig 3e
Abcam Ddb1 antibody (Abcam, ab109027) was used in western blot on human samples at 1:10,000 (fig 3e). Science (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D4C8)
  • western blot; human; 1:1000; loading ...; fig s8b
Cell Signaling Technology Ddb1 antibody (Cell Signaling, 6998) was used in western blot on human samples at 1:1000 (fig s8b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D4C8)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology Ddb1 antibody (CST, 6998) was used in western blot on human samples (fig 2c). Genes Dev (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 4e
Cell Signaling Technology Ddb1 antibody (Cell Signaling, S428) was used in western blot on human samples at 1:1000 (fig 4e). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology Ddb1 antibody (Cell Signaling Technology, 5428) was used in western blot on human samples at 1:1000 (fig 2). Nature (2016) ncbi
domestic rabbit monoclonal (D4C8)
  • western blot; human; fig 5c
Cell Signaling Technology Ddb1 antibody (Cell Signaling, 6998) was used in western blot on human samples (fig 5c). PLoS ONE (2015) ncbi
Articles Reviewed
  1. Liu F, Han Q, Zhang T, Chang F, Deng J, Huang X, et al. CRL4-DCAF8L1 Regulates BRCA1 and BARD1 Protein Stability. Int J Biol Sci. 2022;18:1434-1450 pubmed publisher
  2. Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, et al. AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions. elife. 2020;9: pubmed publisher
  3. Pech M, Fong L, Villalta J, Chan L, Kharbanda S, O Brien J, et al. Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance. elife. 2019;8: pubmed publisher
  4. Silva M, Ferguson F, Cai Q, Donovan K, Nandi G, Patnaik D, et al. Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. elife. 2019;8: pubmed publisher
  5. Hou L, Zhao J, Gao S, Ji T, Song T, Li Y, et al. Restriction of hepatitis B virus replication by c-Abl-induced proteasomal degradation of the viral polymerase. Sci Adv. 2019;5:eaau7130 pubmed publisher
  6. Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, et al. The protective role of DOT1L in UV-induced melanomagenesis. Nat Commun. 2018;9:259 pubmed publisher
  7. Morgan M, Rickels R, Collings C, He X, Cao K, Herz H, et al. A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation. Genes Dev. 2017;31:2003-2014 pubmed publisher
  8. Han T, Goralski M, Gaskill N, Capota E, Kim J, Ting T, et al. Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15. Science. 2017;356: pubmed publisher
  9. Gao S, Geng C, Song T, Lin X, Liu J, Cai Z, et al. Activation of c-Abl Kinase Potentiates the Anti-myeloma Drug Lenalidomide by Promoting DDA1 Protein Recruitment to the CRL4 Ubiquitin Ligase. J Biol Chem. 2017;292:3683-3691 pubmed publisher
  10. Prince E, Balakrishnan I, Shah M, Mulcahy Levy J, Griesinger A, Alimova I, et al. Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma. Oncotarget. 2016;7:53881-53894 pubmed publisher
  11. Kang J, Park S, Jeong S, Han M, Lee C, Lee K, et al. Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation. Proc Natl Acad Sci U S A. 2016;113:8771-6 pubmed publisher
  12. Hrecka K, Hao C, Shun M, Kaur S, Swanson S, Florens L, et al. HIV-1 and HIV-2 exhibit divergent interactions with HLTF and UNG2 DNA repair proteins. Proc Natl Acad Sci U S A. 2016;113:E3921-30 pubmed publisher
  13. Decorsière A, Mueller H, van Breugel P, Abdul F, Gerossier L, Beran R, et al. Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature. 2016;531:386-9 pubmed publisher
  14. Murray H, Maltby V, Smith D, Bowden N. Nucleotide excision repair deficiency in melanoma in response to UVA. Exp Hematol Oncol. 2015;5:6 pubmed publisher
  15. Lyu L, Whitcomb E, Jiang S, Chang M, Gu Y, Duncan M, et al. Unfolded-protein response-associated stabilization of p27(Cdkn1b) interferes with lens fiber cell denucleation, leading to cataract. FASEB J. 2016;30:1087-95 pubmed publisher
  16. Sjögren B, Swaney S, Neubig R. FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex. PLoS ONE. 2015;10:e0123581 pubmed publisher
  17. Liu J, Ye J, Zou X, Xu Z, Feng Y, Zou X, et al. CRL4A(CRBN) E3 ubiquitin ligase restricts BK channel activity and prevents epileptogenesis. Nat Commun. 2014;5:3924 pubmed publisher
  18. Srivastava S, Swanson S, Manel N, Florens L, Washburn M, Skowronski J. Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection. PLoS Pathog. 2008;4:e1000059 pubmed publisher