This is a Validated Antibody Database (VAD) review about mouse Cyr61, based on 7 published articles (read how Labome selects the articles), using Cyr61 antibody in all methods. It is aimed to help Labome visitors find the most suited Cyr61 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cyr61 synonym: AI325051; CCN1; Igfbp10; protein CYR61; 3CH61; CCN family member 1; IBP-10; IGF-binding protein 10; IGFBP-10; cysteine-rich angiogenic inducer 61; insulin-like growth factor-binding protein 10; intermediate early

R&D Systems
rat monoclonal (466305)
  • immunocytochemistry; mouse; 0.5 mg/ml
R&D Systems Cyr61 antibody (R&D Systems, MAB4864) was used in immunocytochemistry on mouse samples at 0.5 mg/ml. Transpl Int (2015) ncbi
sheep polyclonal
  • immunohistochemistry - paraffin section; Domestic guinea pig; fig 5
  • western blot; Domestic guinea pig; fig 3
R&D Systems Cyr61 antibody (R&D Systems, AF 4055) was used in immunohistochemistry - paraffin section on Domestic guinea pig samples (fig 5) and in western blot on Domestic guinea pig samples (fig 3). Innate Immun (2015) ncbi
sheep polyclonal
  • immunohistochemistry - paraffin section; rat
  • western blot; rat
R&D Systems Cyr61 antibody (R&D Systems, AF4055) was used in immunohistochemistry - paraffin section on rat samples and in western blot on rat samples . J Mol Cell Cardiol (2015) ncbi
sheep polyclonal
  • immunoprecipitation; mouse
  • immunohistochemistry; mouse; 1:50
  • western blot; mouse; 1:1000
R&D Systems Cyr61 antibody (R&D Systems, AF4055) was used in immunoprecipitation on mouse samples , in immunohistochemistry on mouse samples at 1:50 and in western blot on mouse samples at 1:1000. Biochim Biophys Acta (2014) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; fig 1
In order to research regulation of cartilage development and chondrocyte maturation by CCN1, Abcam Cyr61 antibody (Abcam, ab24448) was used in immunohistochemistry on mouse samples at 1:500 (fig 1). J Bone Miner Res (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human
  • western blot; human
Abcam Cyr61 antibody (Abcam, ab24448) was used in immunocytochemistry on human samples and in western blot on human samples . J Am Soc Nephrol (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:500
Abcam Cyr61 antibody (Abcam, ab24448) was used in western blot on human samples at 1:500. PLoS ONE (2012) ncbi
Articles Reviewed
  1. Zhang Y, Sheu T, Hoak D, Shen J, Hilton M, Zuscik M, et al. CCN1 Regulates Chondrocyte Maturation and Cartilage Development. J Bone Miner Res. 2016;31:549-59 pubmed publisher
  2. Raissadati A, Nykänen A, Tuuminen R, Syrjälä S, Krebs R, Arnaudova R, et al. Systemic overexpression of matricellular protein CCN1 exacerbates obliterative bronchiolitis in mouse tracheal allografts. Transpl Int. 2015;28:1416-25 pubmed publisher
  3. Shegarfi H, Krohn C, Gundersen Y, Kjeldsen S, Hviid C, Ruud T, et al. Regulation of CCN1 (Cyr61) in a porcine model of intestinal ischemia/reperfusion. Innate Immun. 2015;21:453-62 pubmed publisher
  4. Duggirala A, Kimura T, Sala Newby G, Johnson J, Wu Y, Newby A, et al. cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1. J Mol Cell Cardiol. 2015;79:157-68 pubmed publisher
  5. Borkham Kamphorst E, Schaffrath C, Van De Leur E, Haas U, Tihaa L, Meurer S, et al. The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-? signaling. Biochim Biophys Acta. 2014;1843:902-14 pubmed publisher
  6. Byron A, Randles M, Humphries J, Mironov A, Hamidi H, Harris S, et al. Glomerular cell cross-talk influences composition and assembly of extracellular matrix. J Am Soc Nephrol. 2014;25:953-66 pubmed publisher
  7. Xie H, Zhao Y, Caramuta S, Larsson C, Lui W. miR-205 expression promotes cell proliferation and migration of human cervical cancer cells. PLoS ONE. 2012;7:e46990 pubmed publisher