This is a Validated Antibody Database (VAD) review about mouse Cul2, based on 11 published articles (read how Labome selects the articles), using Cul2 antibody in all methods. It is aimed to help Labome visitors find the most suited Cul2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cul2 synonym: 1300003D18Rik; 4932411N15Rik; AI327301; mKIAA4106

Abcam
domestic rabbit monoclonal (EPR3104(2))
  • western blot; human; loading ...; fig s1d
Abcam Cul2 antibody (Abcam, 166917) was used in western blot on human samples (fig s1d). Cell Death Differ (2022) ncbi
domestic rabbit monoclonal (EPR3104(2))
  • western blot; human; loading ...; fig 5b
Abcam Cul2 antibody (Abcam, ab166917) was used in western blot on human samples (fig 5b). Nat Chem Biol (2017) ncbi
domestic rabbit monoclonal (EPR3104(2))
  • western blot; human; 1:500; fig 4
Abcam Cul2 antibody (Abcam, ab166917) was used in western blot on human samples at 1:500 (fig 4). J Cell Sci (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • western blot; human; 1:1000; loading ...; fig s4b
Santa Cruz Biotechnology Cul2 antibody (Santa Cruz, sc-166506) was used in western blot on human samples at 1:1000 (fig s4b). Nat Commun (2018) ncbi
mouse monoclonal (C-4)
  • western blot; human; 1 ug/ml; loading ...; fig 1E
Santa Cruz Biotechnology Cul2 antibody (Santa cruz, sc-166506) was used in western blot on human samples at 1 ug/ml (fig 1E). J Cell Biol (2016) ncbi
mouse monoclonal (C-4)
  • western blot; human; loading ...; fig 7a
Santa Cruz Biotechnology Cul2 antibody (Santa Cruz, sc-166506) was used in western blot on human samples (fig 7a). Viruses (2016) ncbi
mouse monoclonal (C-4)
  • western blot; human; fig 4a
Santa Cruz Biotechnology Cul2 antibody (Santa Cruz, sc-166506) was used in western blot on human samples (fig 4a). Mol Cell Biol (2016) ncbi
mouse monoclonal (C-4)
  • immunoprecipitation; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 4b
Santa Cruz Biotechnology Cul2 antibody (Santa Cruz, SC-166506) was used in immunoprecipitation on human samples (fig 4b) and in western blot on human samples (fig 4b). J Cell Sci (2014) ncbi
Invitrogen
domestic rabbit recombinant (50H17L12)
  • western blot; human; 1:5000; loading ...; fig 4b
Invitrogen Cul2 antibody (ThermoFisher, 700179) was used in western blot on human samples at 1:5000 (fig 4b). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2a
In order to show that expression of von Hippel-Lindau-anti-green fluorescence protein-affinity-directed protein missile results in near-complete degradation of endogenous GFP-VPS34 and PAWS1-GFP, Invitrogen Cul2 antibody (Invitrogen, 51-1800) was used in western blot on human samples at 1:1000 (fig 2a). Open Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 6s1
In order to study the cullin-RING ubiquitin ligase deneddylation cycle and COP9-signalosome activation by structural and kinetic analysis, Invitrogen Cul2 antibody (Thermo Scientific, 51-1800) was used in western blot on human samples (fig 6s1). elife (2016) ncbi
Articles Reviewed
  1. Fan Y, Hou T, Dan W, Zhu Y, Liu B, Wei Y, et al. ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression. Cell Death Differ. 2022;: pubmed publisher
  2. Smith B, Wang S, Jaime Figueroa S, Harbin A, Wang J, Hamman B, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019;10:131 pubmed publisher
  3. Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, et al. Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Nat Commun. 2018;9:4394 pubmed publisher
  4. Scott D, Hammill J, Min J, Rhee D, Connelly M, Sviderskiy V, et al. Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase. Nat Chem Biol. 2017;13:850-857 pubmed publisher
  5. Fulcher L, MacArtney T, Bozatzi P, Hornberger A, Rojas Fernandez A, Sapkota G. An affinity-directed protein missile system for targeted proteolysis. Open Biol. 2016;6: pubmed
  6. Uematsu K, Okumura F, Tonogai S, Joo Okumura A, Alemayehu D, Nishikimi A, et al. ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation. J Cell Biol. 2016;215:95-106 pubmed
  7. Devadas K, Biswas S, Haleyurgirisetty M, Ragupathy V, Wang X, Lee S, et al. Identification of Host Micro RNAs That Differentiate HIV-1 and HIV-2 Infection Using Genome Expression Profiling Techniques. Viruses. 2016;8: pubmed publisher
  8. Mosadeghi R, Reichermeier K, Winkler M, Schreiber A, Reitsma J, Zhang Y, et al. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. elife. 2016;5: pubmed publisher
  9. Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1α. J Cell Sci. 2016;129:817-30 pubmed publisher
  10. Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, et al. UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation. Mol Cell Biol. 2016;36:394-406 pubmed publisher
  11. Levay K, Slepak V. Regulation of Cop9 signalosome activity by the EF-hand Ca2+-binding protein tescalcin. J Cell Sci. 2014;127:2448-59 pubmed publisher