This is a Validated Antibody Database (VAD) review about mouse Cops5, based on 13 published articles (read how Labome selects the articles), using Cops5 antibody in all methods. It is aimed to help Labome visitors find the most suited Cops5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cops5 synonym: AI303502; CSN5; Jab1; Mov34; Sgn5

Santa Cruz Biotechnology
mouse monoclonal (B-7)
  • immunohistochemistry; mouse; 1:150; loading ...; fig 4c
Santa Cruz Biotechnology Cops5 antibody (Santa Cruz, sc-13157) was used in immunohistochemistry on mouse samples at 1:150 (fig 4c). Technol Cancer Res Treat (2022) ncbi
mouse monoclonal (B-7)
  • western blot; mouse; fig 6b
Santa Cruz Biotechnology Cops5 antibody (Santz Cruz, sc-13157) was used in western blot on mouse samples (fig 6b). Cell Rep (2021) ncbi
mouse monoclonal (B-7)
  • western blot; human; loading ...; fig s6y
Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology Inc, sc-13157) was used in western blot on human samples (fig s6y). Sci Adv (2018) ncbi
mouse monoclonal
  • western blot; human; fig 6
In order to study the cullin-RING ubiquitin ligase deneddylation cycle and COP9-signalosome activation by structural and kinetic analysis, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology, sc-393725) was used in western blot on human samples (fig 6). elife (2016) ncbi
mouse monoclonal
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Cops5 antibody (SCBT, B-7) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (B-7)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Cops5 antibody (SCBT, B-7) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (42)
  • western blot; human
In order to study the effect of neddylation on COP9-Signalosome deneddylase activity, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology, sc-135954) was used in western blot on human samples . Cell Div (2015) ncbi
mouse monoclonal (B-7)
  • western blot; human
In order to examine the relation between cullin 4B variants and intellectual disability, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz, sc-13157) was used in western blot on human samples . Hum Mutat (2015) ncbi
mouse monoclonal (B-7)
  • immunoprecipitation; human
  • western blot; human
In order to study the role in prostate cancer poliferation of a complex containing COP9 subunits 4 and 5 along with sGC-alpha1 and p53, Santa Cruz Biotechnology Cops5 antibody (Santa Cruz Biotechnology, sc-13157) was used in immunoprecipitation on human samples and in western blot on human samples . Mol Endocrinol (2014) ncbi
Invitrogen
mouse monoclonal (2A10)
  • immunocytochemistry; human; loading ...; fig 3b
Invitrogen Cops5 antibody (Thermo Scientific, MA1-23244) was used in immunocytochemistry on human samples (fig 3b). NPJ Breast Cancer (2021) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s7d
Abcam Cops5 antibody (Abcam, ab12323) was used in western blot on human samples (fig s7d). Mol Cancer (2021) ncbi
GeneTex
mouse monoclonal (8H8.5)
  • western blot; mouse
  • immunoprecipitation; human
  • western blot; human
In order to identify the mechanistic link between Cullin neddylation and Myc ubiquitination/degradation, GeneTex Cops5 antibody (GeneTex, GTX70207) was used in western blot on mouse samples , in immunoprecipitation on human samples and in western blot on human samples . Nat Commun (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D15G6)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Cops5 antibody (Cell Signaling, 9444) was used in western blot on human samples (fig 5a). NPJ Breast Cancer (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig ev2f
Cell Signaling Technology Cops5 antibody (Cell Signaling Technology, 6895) was used in western blot on human samples (fig ev2f). EMBO Mol Med (2021) ncbi
BD Biosciences
mouse monoclonal (42/JAB1)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...
In order to propose a tumor-suppressive activity for macrophage migration inhibitory factor in murine skin, BD Biosciences Cops5 antibody (Becton Dickinson, 42) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. FASEB J (2017) ncbi
Articles Reviewed
  1. Jiang Z, Hong J, Zhang J, Wang X, Ma Y, Xiong Z, et al. Treatment with b-AP15 to Inhibit UCHL5 and USP14 Deubiquitinating Activity and Enhance p27 and Cyclin E1 for Tumors with p53 Deficiency. Technol Cancer Res Treat. 2022;21:15330338221119745 pubmed publisher
  2. Liu Z, Wang T, She Y, Wu K, Gu S, Li L, et al. N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer. Mol Cancer. 2021;20:105 pubmed publisher
  3. Chen H, Padia R, Li T, Li Y, Li B, Jin L, et al. Signaling of MK2 sustains robust AP1 activity for triple negative breast cancer tumorigenesis through direct phosphorylation of JAB1. NPJ Breast Cancer. 2021;7:91 pubmed publisher
  4. Yang Y, Leonard M, Luo Z, Yeo S, Bick G, Hao M, et al. Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer. Cell Rep. 2021;34:108822 pubmed publisher
  5. Mondal T, Shivange G, Tihagam R, Lyerly E, Battista M, Talwar D, et al. Unexpected PD-L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies. EMBO Mol Med. 2021;13:e12716 pubmed publisher
  6. Liu Q, Wu Y, Qin Y, Hu J, Xie W, Qin F, et al. Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses. Sci Adv. 2018;4:eaar2824 pubmed publisher
  7. Brocks T, Fedorchenko O, Schliermann N, Stein A, Moll U, Seegobin S, et al. Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin. FASEB J. 2017;31:526-543 pubmed publisher
  8. Mosadeghi R, Reichermeier K, Winkler M, Schreiber A, Reitsma J, Zhang Y, et al. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. elife. 2016;5: pubmed publisher
  9. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  10. Bornstein G, Grossman C. COP9-Signalosome deneddylase activity is enhanced by simultaneous neddylation: insights into the regulation of an enzymatic protein complex. Cell Div. 2015;10:5 pubmed publisher
  11. Chen J, Shin J, Zhao R, Phan L, Wang H, Xue Y, et al. CSN6 drives carcinogenesis by positively regulating Myc stability. Nat Commun. 2014;5:5384 pubmed publisher
  12. Vulto van Silfhout A, Nakagawa T, Bahi Buisson N, Haas S, Hu H, Bienek M, et al. Variants in CUL4B are associated with cerebral malformations. Hum Mutat. 2015;36:106-17 pubmed publisher
  13. Bhansali M, Shemshedini L. COP9 subunits 4 and 5 target soluble guanylyl cyclase ?1 and p53 in prostate cancer cells. Mol Endocrinol. 2014;28:834-45 pubmed publisher