This is a Validated Antibody Database (VAD) review about mouse Cgas, based on 9 published articles (read how Labome selects the articles), using Cgas antibody in all methods. It is aimed to help Labome visitors find the most suited Cgas antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cgas synonym: E330016A19Rik; Mb21d1

Knockout validation
Cell Signaling Technology
monoclonal (D3O8O)
  • western blot knockout validation; mouse; loading ...; fig 3d
  • immunocytochemistry; mouse; loading ...; fig 3a
Cell Signaling Technology Cgas antibody (Cell Signaling Technology, 31659S) was used in western blot knockout validation on mouse samples (fig 3d) and in immunocytochemistry on mouse samples (fig 3a). Cancer Res (2021) ncbi
Abcam
domestic rabbit monoclonal (EPR23611-101)
  • western blot; mouse; fig 5e
Abcam Cgas antibody (Abcam, ab252416) was used in western blot on mouse samples (fig 5e). iScience (2022) ncbi
Cell Signaling Technology
monoclonal (D3O8O)
  • western blot; mouse; loading ...; fig 1b, 4g
Cell Signaling Technology Cgas antibody (CST, 31659S) was used in western blot on mouse samples (fig 1b, 4g). iScience (2022) ncbi
monoclonal (D3O8O)
  • western blot; mouse; 1:1000; loading ...; fig 1e
Cell Signaling Technology Cgas antibody (CST, 31659) was used in western blot on mouse samples at 1:1000 (fig 1e). J Neuroinflammation (2022) ncbi
monoclonal (D3O8O)
  • western blot knockout validation; mouse; loading ...; fig 3d
  • immunocytochemistry; mouse; loading ...; fig 3a
Cell Signaling Technology Cgas antibody (Cell Signaling Technology, 31659S) was used in western blot knockout validation on mouse samples (fig 3d) and in immunocytochemistry on mouse samples (fig 3a). Cancer Res (2021) ncbi
monoclonal (D3O8O)
  • western blot; mouse; 1:500; loading ...; fig 4b, s12a
Cell Signaling Technology Cgas antibody (Cell Signaling, 31659) was used in western blot on mouse samples at 1:500 (fig 4b, s12a). Nat Commun (2020) ncbi
monoclonal (D3O8O)
  • western blot; mouse; 1:1000; fig 4d
Cell Signaling Technology Cgas antibody (CST, 31659) was used in western blot on mouse samples at 1:1000 (fig 4d). MBio (2020) ncbi
monoclonal (D3O8O)
  • immunocytochemistry; mouse; loading ...; fig 3e
  • western blot; mouse; loading ...; fig s1f
Cell Signaling Technology Cgas antibody (Cell Signaling Technology, 31659S) was used in immunocytochemistry on mouse samples (fig 3e) and in western blot on mouse samples (fig s1f). Cell (2019) ncbi
monoclonal (D3O8O)
  • western blot; mouse; loading ...; fig 1d
Cell Signaling Technology Cgas antibody (Cell Signaling Technology, 31659) was used in western blot on mouse samples (fig 1d). Cell Rep (2019) ncbi
monoclonal (D3O8O)
  • immunoprecipitation; human; loading ...; fig 6c
  • western blot; mouse; loading ...; fig 6c
Cell Signaling Technology Cgas antibody (Cell Signaling Technology, 31659) was used in immunoprecipitation on human samples (fig 6c) and in western blot on mouse samples (fig 6c). Cell (2019) ncbi
Articles Reviewed
  1. Zang N, Cui C, Guo X, Song J, Hu H, Yang M, et al. cGAS-STING activation contributes to podocyte injury in diabetic kidney disease. iScience. 2022;25:105145 pubmed publisher
  2. Zhao X, Hu S, Zeng L, Liu X, Song Y, Zhang Y, et al. Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING-mediated T cell activation. iScience. 2022;25:104690 pubmed publisher
  3. Ding R, Li H, Liu Y, Ou W, Zhang X, Chai H, et al. Activating cGAS-STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis. J Neuroinflammation. 2022;19:137 pubmed publisher
  4. Wang Y, Luo M, Chen Y, Wang Y, Zhang B, Ren Z, et al. ZMYND8 Expression in Breast Cancer Cells Blocks T-Lymphocyte Surveillance to Promote Tumor Growth. Cancer Res. 2021;81:174-186 pubmed publisher
  5. von Roemeling C, Wang Y, Qie Y, Yuan H, Zhao H, Liu X, et al. Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity. Nat Commun. 2020;11:1508 pubmed publisher
  6. Ma H, Qian W, Bambousková M, Collins P, Porter S, Byrum A, et al. Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response. MBio. 2020;11: pubmed publisher
  7. Barnett K, Coronas Serna J, Zhou W, Ernandes M, Cao A, Kranzusch P, et al. Phosphoinositide Interactions Position cGAS at the Plasma Membrane to Ensure Efficient Distinction between Self- and Viral DNA. Cell. 2019;: pubmed publisher
  8. Gentili M, Lahaye X, Nadalin F, Nader G, Puig Lombardi E, Hervé S, et al. The N-Terminal Domain of cGAS Determines Preferential Association with Centromeric DNA and Innate Immune Activation in the Nucleus. Cell Rep. 2019;26:2377-2393.e13 pubmed publisher
  9. Dai J, Huang Y, He X, Zhao M, Wang X, Liu Z, et al. Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity. Cell. 2019;: pubmed publisher