This is a Validated Antibody Database (VAD) review about mouse Cftr, based on 11 published articles (read how Labome selects the articles), using Cftr antibody in all methods. It is aimed to help Labome visitors find the most suited Cftr antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cftr synonym: AW495489; Abcc7; cystic fibrosis transmembrane conductance regulator; ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; ATP-binding cassette, subfamily c, member 7; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator homolog; cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7

Knockout validation
Abcam
mouse monoclonal (CF3)
  • western blot knockout validation; mouse; 1:1000; fig 2
Abcam Cftr antibody (Abcam, ab2784) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2). Cell Death Differ (2016) ncbi
Abcam
mouse monoclonal (CF3)
  • immunohistochemistry; human; loading ...; fig 1b
Abcam Cftr antibody (Abcam, 2784) was used in immunohistochemistry on human samples (fig 1b). Sci Rep (2018) ncbi
mouse monoclonal (CF3)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5b
  • immunocytochemistry; human; fig 2i
Abcam Cftr antibody (Abcam, CF3) was used in immunohistochemistry - paraffin section on mouse samples (fig 5b) and in immunocytochemistry on human samples (fig 2i). Nat Med (2017) ncbi
mouse monoclonal (CF3)
  • western blot; human; 1:500; fig 1b
  • western blot; mouse; 1:500; fig 3b
Abcam Cftr antibody (Abcam, ab2784) was used in western blot on human samples at 1:500 (fig 1b) and in western blot on mouse samples at 1:500 (fig 3b). Exp Physiol (2016) ncbi
mouse monoclonal (CF3)
  • western blot knockout validation; mouse; 1:1000; fig 2
Abcam Cftr antibody (Abcam, ab2784) was used in western blot knockout validation on mouse samples at 1:1000 (fig 2). Cell Death Differ (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; tbl 1
  • immunohistochemistry - paraffin section; human; 1:200; tbl 1
Abcam Cftr antibody (Abcam, ab59394) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (tbl 1) and in immunohistochemistry - paraffin section on human samples at 1:200 (tbl 1). Sci Rep (2016) ncbi
mouse monoclonal (CF3)
  • western blot; human; fig s2
Abcam Cftr antibody (Abcam, ab2784) was used in western blot on human samples (fig s2). PLoS ONE (2016) ncbi
mouse monoclonal (CF3)
  • flow cytometry; human; 1:20; fig 1b
Abcam Cftr antibody (Abcam, CF3) was used in flow cytometry on human samples at 1:20 (fig 1b). Curr Cancer Drug Targets (2016) ncbi
mouse monoclonal (CF3)
  • immunohistochemistry; human; fig 3
Abcam Cftr antibody (Abcam, ab2784) was used in immunohistochemistry on human samples (fig 3). Exp Cell Res (2015) ncbi
mouse monoclonal (CF3)
  • immunohistochemistry; pig; 1:50
Abcam Cftr antibody (Abcam, ab2784) was used in immunohistochemistry on pig samples at 1:50. Br J Pharmacol (2014) ncbi
Alomone Labs
rabbit polyclonal
  • western blot; human; 1:200; fig 1
In order to analyze thermal inhalation injury and pulmonary inflammation and the role of CFTR-regulated MAPK/NF-kappa B signaling, Alomone Labs Cftr antibody (Alomone labs, ACL-006) was used in western blot on human samples at 1:200 (fig 1). Sci Rep (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000
  • immunohistochemistry - paraffin section; mouse; 1:1000
  • western blot; mouse; 1:1200
Alomone Labs Cftr antibody (Alomone Labs, ACL-006) was used in immunohistochemistry - paraffin section on human samples at 1:1000, in immunohistochemistry - paraffin section on mouse samples at 1:1000 and in western blot on mouse samples at 1:1200. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Zhang S, Shrestha C, Kopp B. Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function. Sci Rep. 2018;8:17066 pubmed publisher
  2. Romani L, Oikonomou V, Moretti S, Iannitti R, D Adamo M, Villella V, et al. Thymosin ?1 represents a potential potent single-molecule-based therapy for cystic fibrosis. Nat Med. 2017;23:590-600 pubmed publisher
  3. Jin H, Wen G, Deng S, Wan S, Xu J, Liu X, et al. Oestrogen upregulates the expression levels and functional activities of duodenal mucosal CFTR and SLC26A6. Exp Physiol. 2016;101:1371-1382 pubmed publisher
  4. Tosco A, De Gregorio F, Esposito S, De Stefano D, Sana I, Ferrari E, et al. A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR. Cell Death Differ. 2016;23:1380-93 pubmed publisher
  5. Brennan S, Wilkinson W, Tseng H, Finney B, Monk B, Dibble H, et al. The extracellular calcium-sensing receptor regulates human fetal lung development via CFTR. Sci Rep. 2016;6:21975 pubmed publisher
  6. Khoory J, Estanislau J, Elkhal A, Lazaar A, Melhorn M, Brodsky A, et al. Ligation of Glycophorin A Generates Reactive Oxygen Species Leading to Decreased Red Blood Cell Function. PLoS ONE. 2016;11:e0141206 pubmed publisher
  7. Fanelli M, Hattinger C, Vella S, Tavanti E, Michelacci F, Gudeman B, et al. Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma. Curr Cancer Drug Targets. 2016;16:261-74 pubmed
  8. Dong Z, Chen J, Ruan Y, Zhou T, Chen Y, Chen Y, et al. CFTR-regulated MAPK/NF-κB signaling in pulmonary inflammation in thermal inhalation injury. Sci Rep. 2015;5:15946 pubmed publisher
  9. Li H, Chen L, Zeng S, Li X, Zhang X, Lin C, et al. Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice. Exp Cell Res. 2015;332:67-77 pubmed publisher
  10. Zhou M, Fu J, Huang W, Shen L, Xiao L, Song Y, et al. Increased cystic fibrosis transmembrane conductance regulators expression and decreased epithelial sodium channel alpha subunits expression in early abortion: findings from a mouse model and clinical cases of abortion. PLoS ONE. 2014;9:e99521 pubmed publisher
  11. McLatchie L, Young J, Fry C. Regulation of ACh release from guinea pig bladder urothelial cells: potential role in bladder filling sensations. Br J Pharmacol. 2014;171:3394-403 pubmed publisher