This is a Validated Antibody Database (VAD) review about mouse Cdkn2a, based on 50 published articles (read how Labome selects the articles), using Cdkn2a antibody in all methods. It is aimed to help Labome visitors find the most suited Cdkn2a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Cdkn2a synonym: ARF-INK4a; Arf; INK4a-ARF; Ink4a/Arf; MTS1; Pctr1; p16; p16(INK4a); p16INK4a; p19; p19ARF

Knockout validation
Novus Biologicals
rat monoclonal (5-C3-1)
  • western blot knockout validation; mouse; 1:250; loading ...; fig s3
Novus Biologicals Cdkn2a antibody (Novus, NB200-174) was used in western blot knockout validation on mouse samples at 1:250 (fig s3). J Clin Invest (2021) ncbi
Abcam
mouse monoclonal (2D9A12)
  • immunohistochemistry; mouse; 1:100; loading ...; fig ev1d
Abcam Cdkn2a antibody (Abcam, ab54210) was used in immunohistochemistry on mouse samples at 1:100 (fig ev1d). EMBO Mol Med (2022) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry; human; loading ...; fig 3a
Abcam Cdkn2a antibody (Abcam, ab54210) was used in immunohistochemistry on human samples (fig 3a). Cell Death Dis (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4b
Abcam Cdkn2a antibody (Abcam, ab189034) was used in immunohistochemistry - frozen section on mouse samples (fig 4b). Cells (2022) ncbi
domestic rabbit monoclonal (EPR20418)
  • immunohistochemistry - frozen section; mouse; loading ...; fig s1b
Abcam Cdkn2a antibody (Abcam, ab211542) was used in immunohistochemistry - frozen section on mouse samples (fig s1b). Hepatol Commun (2022) ncbi
domestic rabbit monoclonal (EPR20418)
  • western blot; mouse; 1:2000; fig 8c
Abcam Cdkn2a antibody (Abcam, ab211542) was used in western blot on mouse samples at 1:2000 (fig 8c). Cells (2022) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3, 6, 8a
Abcam Cdkn2a antibody (Abcam, ab54210) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 3, 6, 8a). Cells (2022) ncbi
domestic rabbit monoclonal (EPR20418)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 1f
Abcam Cdkn2a antibody (Abcam, ab211542) was used in immunohistochemistry on mouse samples at 1:50 (fig 1f). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4c
Abcam Cdkn2a antibody (Abcam, ab189034) was used in western blot on mouse samples (fig 4c). Aging Cell (2021) ncbi
domestic rabbit monoclonal (EPR20418)
  • immunohistochemistry; mouse; fig 2b
  • western blot; mouse; loading ...; fig 2h
Abcam Cdkn2a antibody (Abcam, ab211542) was used in immunohistochemistry on mouse samples (fig 2b) and in western blot on mouse samples (fig 2h). Signal Transduct Target Ther (2021) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1a
Abcam Cdkn2a antibody (Abcam, ab54210) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1a). Aging (Albany NY) (2021) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry; human; 1:1000
Abcam Cdkn2a antibody (Abcam, 2D9A12) was used in immunohistochemistry on human samples at 1:1000. Ann Med (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 7
Abcam Cdkn2a antibody (Abcam, ab-189034) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 7). Int J Mol Sci (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4a
Abcam Cdkn2a antibody (Abcam, ab189034) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 4a). Cell Death Dis (2020) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry; human; 1:500; loading ...; fig 1a
Abcam Cdkn2a antibody (Abcam, ab54210) was used in immunohistochemistry on human samples at 1:500 (fig 1a). elife (2020) ncbi
mouse monoclonal (2D9A12)
  • western blot; human; loading ...; fig 5d
Abcam Cdkn2a antibody (Santa Cruz, ab54210) was used in western blot on human samples (fig 5d). elife (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s6b
Abcam Cdkn2a antibody (Abcam, ab-80) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s6b). EMBO J (2019) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1c
  • immunohistochemistry - free floating section; mouse; 1:100; loading ...; fig 4d
Abcam Cdkn2a antibody (Abcam, ab54210) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1c) and in immunohistochemistry - free floating section on mouse samples at 1:100 (fig 4d). Nat Neurosci (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 2e
Abcam Cdkn2a antibody (Abcam, ab80) was used in western blot on mouse samples (fig 2e). Cell (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4c
Abcam Cdkn2a antibody (Abcam, ab189034) was used in immunohistochemistry on mouse samples at 1:500 (fig 4c). Cell Death Dis (2018) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; loading ...; fig 1e
Abcam Cdkn2a antibody (Abcam, Ab80) was used in immunocytochemistry on mouse samples (fig 1e). Cell Stem Cell (2017) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 3i
In order to elucidate novel functions of the senescence-associated secretory in promoting a proregenerative response through the induction of cell plasticity and stemness, Abcam Cdkn2a antibody (Abcam, 2D9A12) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 3i). Genes Dev (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s3a
In order to elucidate novel functions of the senescence-associated secretory in promoting a proregenerative response through the induction of cell plasticity and stemness, Abcam Cdkn2a antibody (Abcam, ab80) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig s3a). Genes Dev (2017) ncbi
mouse monoclonal (2D9A12)
  • western blot; human; loading ...; fig 8a
Abcam Cdkn2a antibody (Abcam, ab54210) was used in western blot on human samples (fig 8a). J Cell Physiol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s6
In order to discover a role for H3K27 methylation in governing chondrocyte proliferation and hypertrophy in the growth plate, Abcam Cdkn2a antibody (abcam, ab189034) was used in western blot on mouse samples at 1:1000 (fig s6). Nat Commun (2016) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry - paraffin section; mouse; 1:1000; fig s5
In order to discover a role for H3K27 methylation in governing chondrocyte proliferation and hypertrophy in the growth plate, Abcam Cdkn2a antibody (abcam, ab54210) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig s5). Nat Commun (2016) ncbi
mouse monoclonal (2D9A12)
  • western blot; human; loading ...; fig 1b
Abcam Cdkn2a antibody (Abcam, ab54210) was used in western blot on human samples (fig 1b). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4e
In order to find a role for RelA in regulating oncogene-induced senescence, Abcam Cdkn2a antibody (Abcam, ab80) was used in immunohistochemistry - paraffin section on mouse samples (fig 4e). J Clin Invest (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; fig 5
In order to elucidate inhibition of BCL-W and BCL-XL by directed elimination of senescent cells, Abcam Cdkn2a antibody (abcam, ab3642) was used in immunohistochemistry - paraffin section on human samples (fig 5). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; fig 3a
Abcam Cdkn2a antibody (Abcam, Ab80) was used in western blot on mouse samples at 1:2000 (fig 3a). Oncotarget (2016) ncbi
mouse monoclonal (2D9A12)
  • western blot; mouse; fig 4
Abcam Cdkn2a antibody (Abcam, ab54210) was used in western blot on mouse samples (fig 4). Autophagy (2015) ncbi
rat monoclonal (5-C3)
  • western blot; human
Abcam Cdkn2a antibody (Abcam, ab26696) was used in western blot on human samples . Oncogene (2016) ncbi
rat monoclonal (5-C3)
  • western blot; mouse; loading ...
In order to study the role of Jnk2 in mitophagy., Abcam Cdkn2a antibody (abcam, ab26696) was used in western blot on mouse samples . Nat Immunol (2015) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry - paraffin section; human
In order to study the clinical and pathological findings of two unusual cases of Bowen's disease, Abcam Cdkn2a antibody (Abcam, 2D9A12) was used in immunohistochemistry - paraffin section on human samples . J Dermatol (2015) ncbi
mouse monoclonal (2D9A12)
  • western blot; human; fig 7
Abcam Cdkn2a antibody (Abcam, ab54210) was used in western blot on human samples (fig 7). Oncogene (2015) ncbi
mouse monoclonal (2D9A12)
  • immunohistochemistry - paraffin section; human; 1:200; fig 3
  • western blot; human; 1:1000; fig 1
Abcam Cdkn2a antibody (Abcam, ab54210) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 3) and in western blot on human samples at 1:1000 (fig 1). Arthritis Res Ther (2014) ncbi
mouse monoclonal (2D9A12)
  • western blot; human
Abcam Cdkn2a antibody (Abcam, ab54210) was used in western blot on human samples . Age (Dordr) (2013) ncbi
Invitrogen
mouse monoclonal (1E12E10)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s2
Invitrogen Cdkn2a antibody (Thermo Scientific, MA5-17142) was used in immunohistochemistry - paraffin section on mouse samples (fig s2). Cells (2022) ncbi
mouse monoclonal (1E12E10)
  • immunohistochemistry; mouse; loading ...; fig 5b
Invitrogen Cdkn2a antibody (Invitrogen, MA5-17142) was used in immunohistochemistry on mouse samples (fig 5b). Exp Mol Med (2021) ncbi
mouse monoclonal (1E12E10)
  • immunohistochemistry - paraffin section; human; 1:10,000; loading ...; fig s7b
  • immunohistochemistry - paraffin section; mouse; 1:10,000; loading ...; fig s6c
Invitrogen Cdkn2a antibody (Invitrogen, MA5-17142) was used in immunohistochemistry - paraffin section on human samples at 1:10,000 (fig s7b) and in immunohistochemistry - paraffin section on mouse samples at 1:10,000 (fig s6c). Cardiovasc Res (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 3e
In order to show that ROS-induced DNA damage reduces metabolic activity, inhibits proliferation, and induces cell cycle arrest followed by activation of p16-, p21-, and p27- mediated DNA damage response pathways, premature senescence, and apoptosis induction, Invitrogen Cdkn2a antibody (Thermo Scientific, PA5-16639) was used in western blot on human samples (fig 3e). Exp Cell Res (2017) ncbi
rat monoclonal (12-A1-1)
  • immunohistochemistry; mouse; fig 1
  • western blot; mouse; fig 1
In order to analyze the induction of tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo due to loss of keratin 17, Invitrogen Cdkn2a antibody (Thermo Scientific, MA1-16664) was used in immunohistochemistry on mouse samples (fig 1) and in western blot on mouse samples (fig 1). Oncogene (2016) ncbi
domestic rabbit polyclonal
In order to use transgenic mice to show that CDK5 activity is crucial for cell cycle progression and medullary thyroid carcinoma proliferation, Invitrogen Cdkn2a antibody (Pierce, PA5-20379) was used . Oncotarget (2015) ncbi
domestic rabbit polyclonal
In order to elucidate how GREM1 contributes to hereditary mixed polyposis syndrome, Invitrogen Cdkn2a antibody (Thermoscientific, PA1-30670) was used . Nat Med (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-7)
  • western blot; mouse; loading ...; fig 6c
Santa Cruz Biotechnology Cdkn2a antibody (Santa Cruz, sc-377412) was used in western blot on mouse samples (fig 6c). Proc Natl Acad Sci U S A (2021) ncbi
mouse monoclonal (C-7)
  • western blot; rat; loading ...; fig 5a
Santa Cruz Biotechnology Cdkn2a antibody (Santa Cruz Biotechnology, sc-377412) was used in western blot on rat samples (fig 5a). Mol Med Rep (2020) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; loading ...; fig 2j
Santa Cruz Biotechnology Cdkn2a antibody (Santa, sc-377412) was used in western blot on mouse samples (fig 2j). Aging Cell (2019) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; fig s2
Santa Cruz Biotechnology Cdkn2a antibody (Santa Cruz, sc-377412) was used in western blot on mouse samples (fig s2). Sci Rep (2016) ncbi
mouse monoclonal (C-7)
  • western blot; human; 1:500; fig 2
Santa Cruz Biotechnology Cdkn2a antibody (Santa Cruz, sc-377412) was used in western blot on human samples at 1:500 (fig 2). Nat Commun (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal (KBB36)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1g
Novus Biologicals Cdkn2a antibody (Novus, NB200-106) was used in immunohistochemistry on mouse samples at 1:100 (fig 1g). Nat Commun (2021) ncbi
domestic rabbit polyclonal (26C593.2)
  • immunocytochemistry; human; loading ...; fig 3a
  • western blot; human; loading ...; fig 3d
Novus Biologicals Cdkn2a antibody (Novus, NB200-111) was used in immunocytochemistry on human samples (fig 3a) and in western blot on human samples (fig 3d). EMBO J (2021) ncbi
rat monoclonal (5-C3-1)
  • western blot knockout validation; mouse; 1:250; loading ...; fig s3
Novus Biologicals Cdkn2a antibody (Novus, NB200-174) was used in western blot knockout validation on mouse samples at 1:250 (fig s3). J Clin Invest (2021) ncbi
domestic rabbit polyclonal (KBB36)
  • immunohistochemistry; mouse; loading ...; fig s4c
In order to find a role for chicken ovalbumin upstream promoter-transcription factor II in a murine model of duchenne muscular dystrophy, Novus Biologicals Cdkn2a antibody (Novus Biologicals, NB200-106) was used in immunohistochemistry on mouse samples (fig s4c). J Clin Invest (2016) ncbi
Abnova
rat monoclonal (12-A1-1)
  • western blot; mouse; 1:500; loading ...; fig 7b
Abnova Cdkn2a antibody (Abnova, MAB2416) was used in western blot on mouse samples at 1:500 (fig 7b). Aging (Albany NY) (2020) ncbi
Rockland Immunochemicals
rat monoclonal (5.C3.1)
  • western blot; mouse; fig 4
Rockland Immunochemicals Cdkn2a antibody (Rockland Antibodies and Assays, 5.C3.1) was used in western blot on mouse samples (fig 4). Cell Rep (2015) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 2h
MilliporeSigma Cdkn2a antibody (Sigma, SAB4500072) was used in western blot on mouse samples at 1:2000 (fig 2h). Exp Hematol (2016) ncbi
Articles Reviewed
  1. Paldor M, Levkovitch Siany O, Eidelshtein D, Adar R, Enk C, Marmary Y, et al. Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis. EMBO Mol Med. 2022;14:e15653 pubmed publisher
  2. Chen J, Chen K, Wang L, Luo J, Zheng Q, He Y. Decoy receptor 2 mediates the apoptosis-resistant phenotype of senescent renal tubular cells and accelerates renal fibrosis in diabetic nephropathy. Cell Death Dis. 2022;13:522 pubmed publisher
  3. Mancinelli R, Ceci L, Kennedy L, Francis H, Meadows V, Chen L, et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. Cells. 2022;11: pubmed publisher
  4. O Brien A, Zhou T, White T, Medford A, Chen L, Kyritsi K, et al. FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2-/- Mouse Model of Primary Sclerosing Cholangitis. Hepatol Commun. 2022;6:1574-1588 pubmed publisher
  5. Safwan Zaiter H, Wagner N, Michiels J, Wagner K. Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022;11: pubmed publisher
  6. Novais E, Tran V, Johnston S, Darris K, Roupas A, Sessions G, et al. Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice. Nat Commun. 2021;12:5213 pubmed publisher
  7. Lee H, Donati A, Feliers D, Sun Y, Ding Y, Madesh M, et al. Chloride channel accessory 1 integrates chloride channel activity and mTORC1 in aging-related kidney injury. Aging Cell. 2021;20:e13407 pubmed publisher
  8. Gan L, Liu D, Liu J, Chen E, Chen C, Liu L, et al. CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice. Signal Transduct Target Ther. 2021;6:223 pubmed publisher
  9. Repenning A, Happel D, Bouchard C, Meixner M, Verel Yilmaz Y, Raifer H, et al. PRMT1 promotes the tumor suppressor function of p14ARF and is indicative for pancreatic cancer prognosis. EMBO J. 2021;40:e106777 pubmed publisher
  10. Huang P, Bai L, Liu L, Fu J, Wu K, Liu H, et al. Redd1 knockdown prevents doxorubicin-induced cardiac senescence. Aging (Albany NY). 2021;13:13788-13806 pubmed publisher
  11. Lee S, Park K, Lee G, Kim S, Song W, Kwon S, et al. Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss. Exp Mol Med. 2021;53:591-604 pubmed publisher
  12. Azzimonti B, Raimondo L, Squarzanti D, Rosso T, Zanetta P, Aluffi Valletti P, et al. Macrophages expressing TREM-1 are involved in the progression of HPV16-related oropharyngeal squamous cell carcinoma. Ann Med. 2021;53:541-550 pubmed publisher
  13. Blasiak J, Koskela A, Pawlowska E, Liukkonen M, Ruuth J, Toropainen E, et al. Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice. Int J Mol Sci. 2021;22: pubmed publisher
  14. Chibaya L, Karim B, Zhang H, Jones S. Mdm2 phosphorylation by Akt regulates the p53 response to oxidative stress to promote cell proliferation and tumorigenesis. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  15. Liang X, Yan Z, Ma W, Qian Y, Zou X, Cui Y, et al. Peroxiredoxin 4 protects against ovarian ageing by ameliorating D-galactose-induced oxidative damage in mice. Cell Death Dis. 2020;11:1053 pubmed publisher
  16. Deland K, Starr B, Mercer J, Byemerwa J, Crabtree D, Williams N, et al. Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models. J Clin Invest. 2021;131: pubmed publisher
  17. Cherif H, Bisson D, Mannarino M, Rabau O, Ouellet J, Haglund L. Senotherapeutic drugs for human intervertebral disc degeneration and low back pain. elife. 2020;9: pubmed publisher
  18. Hu D, Dong R, Zhang Y, Yang Y, Chen Z, Tang Y, et al. Age‑related changes in mineralocorticoid receptors in rat hearts. Mol Med Rep. 2020;22:1859-1867 pubmed publisher
  19. Cooper H, Cicalese S, Preston K, Kawai T, Okuno K, Choi E, et al. Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm. Cardiovasc Res. 2021;117:971-982 pubmed publisher
  20. Alessio N, Squillaro T, Di Bernardo G, Galano G, De Rosa R, Melone M, et al. Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence. elife. 2020;9: pubmed publisher
  21. Zhang C, Xie Y, Chen H, Lv L, Yao J, Zhang M, et al. FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Aging (Albany NY). 2020;12:1272-1284 pubmed publisher
  22. Gal H, Lysenko M, Stroganov S, Vadai E, Youssef S, Tzadikevitch Geffen K, et al. Molecular pathways of senescence regulate placental structure and function. EMBO J. 2019;38:e100849 pubmed publisher
  23. Zhang P, Kishimoto Y, Grammatikakis I, Gottimukkala K, Cutler R, Zhang S, et al. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model. Nat Neurosci. 2019;22:719-728 pubmed publisher
  24. Chen L, Yang R, Qiao W, Zhang W, Chen J, Mao L, et al. 1,25-Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2-antioxidant signaling and inactivation of p16/p53-senescence signaling. Aging Cell. 2019;18:e12951 pubmed publisher
  25. Xiao G, Chan L, Klemm L, Braas D, Chen Z, Geng H, et al. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018;173:470-484.e18 pubmed publisher
  26. Chen K, Dai H, Yuan J, Chen J, Lin L, Zhang W, et al. Optineurin-mediated mitophagy protects renal tubular epithelial cells against accelerated senescence in diabetic nephropathy. Cell Death Dis. 2018;9:105 pubmed publisher
  27. Ruetz T, Pfisterer U, Di Stefano B, Ashmore J, Beniazza M, Tian T, et al. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 2017;21:791-805.e9 pubmed publisher
  28. Ritschka B, Storer M, Mas A, Heinzmann F, Ortells M, Morton J, et al. The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration. Genes Dev. 2017;31:172-183 pubmed publisher
  29. Squillaro T, Antonucci I, Alessio N, Esposito A, Cipollaro M, Melone M, et al. Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes. J Cell Physiol. 2017;232:3454-3467 pubmed publisher
  30. Mytych J, Wos I, Solek P, Koziorowski M. Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes. Exp Cell Res. 2017;350:358-367 pubmed publisher
  31. Lui J, Garrison P, Nguyen Q, Ad M, Keembiyehetty C, Chen W, et al. EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy. Nat Commun. 2016;7:13685 pubmed publisher
  32. Saia M, Termanini A, Rizzi N, Mazza M, Barbieri E, Valli D, et al. AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells. Sci Rep. 2016;6:34957 pubmed publisher
  33. Xie X, Tsai S, Tsai M. COUP-TFII regulates satellite cell function and muscular dystrophy. J Clin Invest. 2016;126:3929-3941 pubmed publisher
  34. Mirkheshti N, Park S, Jiang S, Cropper J, Werner S, Song C, et al. Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer. Oncotarget. 2016;7:62240-62254 pubmed publisher
  35. Lesina M, Wörmann S, Morton J, Diakopoulos K, Korneeva O, Wimmer M, et al. RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis. J Clin Invest. 2016;126:2919-32 pubmed publisher
  36. Hobbs R, Batazzi A, Han M, Coulombe P. Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo. Oncogene. 2016;35:5653-5662 pubmed publisher
  37. Yosef R, Pilpel N, Tokarsky Amiel R, Biran A, Ovadya Y, Cohen S, et al. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL. Nat Commun. 2016;7:11190 pubmed publisher
  38. Lee H, Dai F, Zhuang L, Xiao Z, Kim J, Zhang Y, et al. BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21. Oncotarget. 2016;7:19134-46 pubmed publisher
  39. Largeot A, Perez Campo F, Marinopoulou E, Lie A Ling M, Kouskoff V, Lacaud G. Expression of the MOZ-TIF2 oncoprotein in mice represses senescence. Exp Hematol. 2016;44:231-7.e4 pubmed publisher
  40. Grootaert M, da Costa Martins P, Bitsch N, Pintelon I, De Meyer G, Martinet W, et al. Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy. 2015;11:2014-2032 pubmed publisher
  41. Lee C, Yang Y, Chen C, Liu J. Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell death. Oncogene. 2016;35:1988-95 pubmed publisher
  42. Sedic M, Skibinski A, Brown N, Gallardo M, Mulligan P, Martinez P, et al. Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence. Nat Commun. 2015;6:7505 pubmed publisher
  43. Pozo K, Hillmann A, Augustyn A, Plattner F, Hai T, Singh T, et al. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget. 2015;6:12080-93 pubmed
  44. Zhang Q, Kuang H, Chen C, Yan J, Do Umehara H, Liu X, et al. The kinase Jnk2 promotes stress-induced mitophagy by targeting the small mitochondrial form of the tumor suppressor ARF for degradation. Nat Immunol. 2015;16:458-66 pubmed publisher
  45. Aubrey B, Kelly G, Kueh A, Brennan M, O Connor L, Milla L, et al. An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo. Cell Rep. 2015;10:1422-32 pubmed publisher
  46. Davis H, Irshad S, Bansal M, Rafferty H, Boitsova T, Bardella C, et al. Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. Nat Med. 2015;21:62-70 pubmed publisher
  47. Hsu C, Chen Y, Yang W, Hsu K, Chao S, Lee J. Bowen's disease with features resembling myrmecia wart. J Dermatol. 2015;42:90-3 pubmed publisher
  48. Wang W, Catto J, Meuth M. Differential response of normal and malignant urothelial cells to CHK1 and ATM inhibitors. Oncogene. 2015;34:2887-96 pubmed publisher
  49. Philipot D, Guérit D, Platano D, Chuchana P, Olivotto E, Espinoza F, et al. p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis. Arthritis Res Ther. 2014;16:R58 pubmed publisher
  50. Zhang B, Cui S, Bai X, Zhuo L, Sun X, Hong Q, et al. SIRT3 overexpression antagonizes high glucose accelerated cellular senescence in human diploid fibroblasts via the SIRT3-FOXO1 signaling pathway. Age (Dordr). 2013;35:2237-53 pubmed publisher