This is a Validated Antibody Database (VAD) review about mouse Ccr4, based on 23 published articles (read how Labome selects the articles), using Ccr4 antibody in all methods. It is aimed to help Labome visitors find the most suited Ccr4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ccr4 synonym: C-C CKR-4; CHEMR1; Cmkbr4; LESTR; Sdf1r

BioLegend
hamsters monoclonal (2G12)
  • flow cytometry; mouse; fig 3e
BioLegend Ccr4 antibody (BioLegend, 131211) was used in flow cytometry on mouse samples (fig 3e). Clin Transl Med (2022) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; 1:100; loading ...; fig s1d
BioLegend Ccr4 antibody (Biolegend, 2G12) was used in flow cytometry on mouse samples at 1:100 (fig s1d). J Neuroinflammation (2022) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; loading ...
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in flow cytometry on mouse samples . Front Immunol (2021) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; loading ...; fig s2g
BioLegend Ccr4 antibody (Biolegend, 2G12) was used in flow cytometry on mouse samples (fig s2g). J Clin Invest (2021) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; 1:100; loading ...; fig s6d, e
BioLegend Ccr4 antibody (Biolegend, 131203) was used in flow cytometry on mouse samples at 1:100 (fig s6d, e). Nat Commun (2020) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; 1:200; loading ...; fig ex10a
BioLegend Ccr4 antibody (BioLegend, 131214) was used in flow cytometry on mouse samples at 1:200 (fig ex10a). Nature (2019) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; loading ...; fig 7b
BioLegend Ccr4 antibody (Biolegend, 131204) was used in flow cytometry on mouse samples (fig 7b). Nat Commun (2018) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; loading ...; fig 4b
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in flow cytometry on mouse samples (fig 4b). Front Immunol (2018) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; human; loading ...; fig 1a
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in flow cytometry on human samples (fig 1a). Bone Marrow Transplant (2018) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; 1:200; loading ...; fig s5a
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in flow cytometry on mouse samples at 1:200 (fig s5a). J Clin Invest (2018) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; fig s1f
BioLegend Ccr4 antibody (Biolegend, 131211) was used in flow cytometry on mouse samples (fig s1f). Immunity (2017) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; fig 3d
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in flow cytometry on mouse samples (fig 3d). Proc Natl Acad Sci U S A (2017) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; fig 5d
In order to investigate the role of general control non-derepressible 2 in resolving autoimmune neuroinflammation, BioLegend Ccr4 antibody (Biolegend, 2G12) was used in flow cytometry on mouse samples (fig 5d). J Neuroimmunol (2016) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse; loading ...; fig 4a
In order to ask if T-bet regulates other T regulatory cell functions after entering the inflammatory site, BioLegend Ccr4 antibody (Biolegend, 2G12) was used in flow cytometry on mouse samples (fig 4a). J Immunol (2016) ncbi
hamsters monoclonal (2G12)
BioLegend Ccr4 antibody (Biolegend, 131211) was used . Nat Commun (2015) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse
In order to report that AMPK regulates protein phosphatase activity to control the of survival and function of CD8+ T cells, thus regulating immune surveillance of tumors, BioLegend Ccr4 antibody (Biolegend, 2G12) was used in flow cytometry on mouse samples . Oncotarget (2015) ncbi
hamsters monoclonal (2G12)
  • western blot; mouse; 1:100; fig 5,6
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in western blot on mouse samples at 1:100 (fig 5,6). Nat Commun (2015) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in flow cytometry on mouse samples . J Immunol (2015) ncbi
hamsters monoclonal (2G12)
BioLegend Ccr4 antibody (BioLegend, 2G12) was used . J Immunol (2014) ncbi
hamsters monoclonal (2G12)
  • flow cytometry; mouse
BioLegend Ccr4 antibody (BioLegend, 2G12) was used in flow cytometry on mouse samples . Nat Immunol (2014) ncbi
hamsters monoclonal (2G12)
BioLegend Ccr4 antibody (BioLegend, 2G12) was used . J Leukoc Biol (2014) ncbi
hamsters monoclonal (2G12)
BioLegend Ccr4 antibody (BioLegend, 2G12) was used . J Immunol (2014) ncbi
Abcam
domestic goat polyclonal
  • immunohistochemistry - paraffin section; human; 1:300; loading ...; fig s1a
  • flow cytometry; human; loading ...; fig s2
In order to assess the use of anti-CCR4 antibody in a mouse model of renal cell carcinoma, Abcam Ccr4 antibody (Abcam, ab1669) was used in immunohistochemistry - paraffin section on human samples at 1:300 (fig s1a) and in flow cytometry on human samples (fig s2). J Clin Invest (2017) ncbi
Articles Reviewed
  1. Baik J, Park H, Kataru R, Savetsky I, Ly C, Shin J, et al. TGF-β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation. Clin Transl Med. 2022;12:e758 pubmed publisher
  2. Benkhoucha M, Tran N, Breville G, Senoner I, Bradfield P, Papayannopoulou T, et al. CD4+c-Met+Itgα4+ T cell subset promotes murine neuroinflammation. J Neuroinflammation. 2022;19:103 pubmed publisher
  3. Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
  4. Harro C, Perez Sanz J, Costich T, Payne K, Anadon C, Chaurio R, et al. Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. J Clin Invest. 2021;131: pubmed publisher
  5. Aslan K, Turco V, Blobner J, Sonner J, Liuzzi A, Núñez N, et al. Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas. Nat Commun. 2020;11:931 pubmed publisher
  6. Oh J, Iijima N, Song E, Lu P, Klein J, Jiang R, et al. Migrant memory B cells secrete luminal antibody in the vagina. Nature. 2019;: pubmed publisher
  7. Tordesillas L, Lozano Ojalvo D, Dunkin D, Mondoulet L, Agudo J, Merad M, et al. PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs. Nat Commun. 2018;9:5238 pubmed publisher
  8. Ushio A, Arakaki R, Otsuka K, Yamada A, Tsunematsu T, Kudo Y, et al. CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome. Front Immunol. 2018;9:2594 pubmed publisher
  9. Inoue Y, Endo S, Matsuno N, Kikukawa Y, Shichijo T, Koga K, et al. Safety of mogamulizumab for relapsed ATL after allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2018;: pubmed publisher
  10. Hailemichael Y, Woods A, Fu T, He Q, Nielsen M, Hasan F, et al. Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy. J Clin Invest. 2018;128:1338-1354 pubmed publisher
  11. Kishore M, Cheung K, Fu H, Bonacina F, Wang G, Coe D, et al. Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis. Immunity. 2017;47:875-889.e10 pubmed publisher
  12. Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, et al. Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development. Proc Natl Acad Sci U S A. 2017;114:10443-10448 pubmed publisher
  13. Berlato C, Khan M, Schioppa T, Thompson R, Maniati E, Montfort A, et al. A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. J Clin Invest. 2017;127:801-813 pubmed publisher
  14. Keil M, Sonner J, Lanz T, Oezen I, Bunse T, Bittner S, et al. General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation. J Neuroimmunol. 2016;297:117-26 pubmed publisher
  15. Xiong Y, Ahmad S, Iwami D, Brinkman C, Bromberg J. T-bet Regulates Natural Regulatory T Cell Afferent Lymphatic Migration and Suppressive Function. J Immunol. 2016;196:2526-40 pubmed publisher
  16. Zanvit P, Konkel J, Jiao X, Kasagi S, Zhang D, Wu R, et al. Antibiotics in neonatal life increase murine susceptibility to experimental psoriasis. Nat Commun. 2015;6:8424 pubmed publisher
  17. Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
  18. Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, et al. Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353 pubmed publisher
  19. Yuan X, Dee M, Altman N, Malek T. IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa. J Immunol. 2015;194:1334-46 pubmed publisher
  20. Cowan J, McCarthy N, Parnell S, White A, Bacon A, Serge A, et al. Differential requirement for CCR4 and CCR7 during the development of innate and adaptive ??T cells in the adult thymus. J Immunol. 2014;193:1204-12 pubmed publisher
  21. Vegran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, et al. The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nat Immunol. 2014;15:758-66 pubmed publisher
  22. Xia S, Wei J, Wang J, Sun H, Zheng W, Li Y, et al. A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells. J Leukoc Biol. 2014;95:733-742 pubmed
  23. Brenndörfer E, Brass A, Karthe J, Ahlen G, Bode J, Sallberg M. Cleavage of the T cell protein tyrosine phosphatase by the hepatitis C virus nonstructural 3/4A protease induces a Th1 to Th2 shift reversible by ribavirin therapy. J Immunol. 2014;192:1671-80 pubmed publisher