This is a Validated Antibody Database (VAD) review about mouse Casp12, based on 10 published articles (read how Labome selects the articles), using Casp12 antibody in all methods. It is aimed to help Labome visitors find the most suited Casp12 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Casp12 synonym: caspase-12; CASP-12

Knockout validation
Sigma-Aldrich
rat monoclonal (14F7)
  • western blot knockout validation; mouse; loading ...; fig s1a
In order to study the roles caspase-11 and caspase-12 in obesity and insulin resistance, Sigma-Aldrich Casp12 antibody (Sigma, C7611) was used in western blot knockout validation on mouse samples (fig s1a). J Immunol (2016) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4g
In order to elucidate the mechanism by which the I4895T mutation in the type 1 ryanodine receptor/Ca(2+) release channel results in disease, Cell Signaling Technology Casp12 antibody (Cell Signaling, 2202) was used in western blot on mouse samples at 1:1000 (fig 4g). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Casp12 antibody (Cell Signaling, 2202S) was used in western blot on human samples (fig 4a). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
Cell Signaling Technology Casp12 antibody (CST, v2202) was used in western blot on human samples at 1:1000 (fig 1). Cell Death Dis (2016) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology Casp12 antibody (CST, 2202) was used in western blot on mouse samples (fig 4a). J Gerontol A Biol Sci Med Sci (2017) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology Casp12 antibody (cell signaling, #2202) was used in western blot on mouse samples . Biochem Pharmacol (2015) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
In order to study an increase in tau phosphorylation via P38 mitogen-activated protein kinase dye to glucose deprivation, Cell Signaling Technology Casp12 antibody (Cell signaling, 2202) was used in western blot on mouse samples (fig 4). Aging Cell (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5
In order to analyze the process of neuronal cell death after traumatic brain injury due to impaired autophagy flux, Cell Signaling Technology Casp12 antibody (Cell Signaling, 2202) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5). Autophagy (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 2
In order to study ZAP-defective human cancers and a characterization of alphavirus M1 as a selective oncolytic virus, Cell Signaling Technology Casp12 antibody (Cell Signaling Technology, 2202) was used in western blot on human samples (fig 2). Proc Natl Acad Sci U S A (2014) ncbi
Sigma-Aldrich
rat monoclonal (14F7)
  • western blot knockout validation; mouse; loading ...; fig s1a
In order to study the roles caspase-11 and caspase-12 in obesity and insulin resistance, Sigma-Aldrich Casp12 antibody (Sigma, C7611) was used in western blot knockout validation on mouse samples (fig s1a). J Immunol (2016) ncbi
rat monoclonal (14F7)
  • western blot; mouse
In order to investigate the role of gp210/Nup210 in muscle cell differentiation, Sigma-Aldrich Casp12 antibody (Sigma-Aldrich, C7611) was used in western blot on mouse samples . J Cell Biol (2015) ncbi
Articles Reviewed
  1. Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  2. Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
  3. Anta B, Pérez Rodríguez A, Castro J, García Domínguez C, Ibiza S, Martínez N, et al. PGA1-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes. Cell Death Dis. 2016;7:e2311 pubmed publisher
  4. Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed publisher
  5. Skeldon A, Morizot A, Douglas T, Santoro N, Kursawe R, Kozlitina J, et al. Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance. J Immunol. 2016;196:437-47 pubmed publisher
  6. Wolter S, Kloth C, Golombek M, Dittmar F, Försterling L, Seifert R. cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines. Biochem Pharmacol. 2015;98:119-31 pubmed publisher
  7. Lauretti E, Praticò D. Glucose deprivation increases tau phosphorylation via P38 mitogen-activated protein kinase. Aging Cell. 2015;14:1067-74 pubmed publisher
  8. Gomez Cavazos J, Hetzer M. The nucleoporin gp210/Nup210 controls muscle differentiation by regulating nuclear envelope/ER homeostasis. J Cell Biol. 2015;208:671-81 pubmed publisher
  9. Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden A, Lipinski M. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy. 2014;10:2208-22 pubmed publisher
  10. Lin Y, Zhang H, Liang J, Li K, Zhu W, Fu L, et al. Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers. Proc Natl Acad Sci U S A. 2014;111:E4504-12 pubmed publisher