This is a Validated Antibody Database (VAD) review about mouse CB1, based on 13 published articles (read how Labome selects the articles), using CB1 antibody in all methods. It is aimed to help Labome visitors find the most suited CB1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CB1 synonym: CB-R; CB1; CB1A; CB1B; CB1R

Synaptic Systems
mouse monoclonal (289C1)
  • immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 6a
Synaptic Systems CB1 antibody (Synaptic systems, 258011) was used in immunohistochemistry - frozen section on mouse samples at 1:500 (fig 6a). Nat Commun (2022) ncbi
guinea-pigs polyclonal
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 2d
Synaptic Systems CB1 antibody (Synaptic Systems, 258-104) was used in immunohistochemistry on mouse samples at 1:2000 (fig 2d). Neural Dev (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 6b
Synaptic Systems CB1 antibody (Synaptic Systems, 258 003) was used in immunohistochemistry on mouse samples at 1:2000 (fig 6b). J Comp Neurol (2019) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 1a
Abcam CB1 antibody (Abcam, ab23703) was used in immunohistochemistry on human samples (fig 4a) and in western blot on human samples (fig 1a). Viruses (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:1000; loading ...; fig 5a, 5d
  • western blot; rat; 1:500; loading ...; fig 6a, 6c
Abcam CB1 antibody (Abcam, ab23703) was used in immunohistochemistry - paraffin section on rat samples at 1:1000 (fig 5a, 5d) and in western blot on rat samples at 1:500 (fig 6a, 6c). Int J Mol Sci (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; pigs ; 1:100; loading ...; fig 1b
Abcam CB1 antibody (Abcam, ab23703) was used in immunohistochemistry - frozen section on pigs samples at 1:100 (fig 1b). Animals (Basel) (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:300; fig 2
Abcam CB1 antibody (Abcam, ab23703) was used in immunocytochemistry on human samples at 1:300 (fig 2). CNS Neurosci Ther (2016) ncbi
domestic rabbit polyclonal
Abcam CB1 antibody (Abcam, ab23703) was used . Arthritis Res Ther (2015) ncbi
Frontier Institute
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1c
Frontier Institute CB1 antibody (Frontier Institute Co, CB1-GP-Af530) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1c). elife (2020) ncbi
  • other; mouse; 1:100; fig 2
  • immunohistochemistry; mouse; 1:500; fig 1
Frontier Institute CB1 antibody (Frontier Institute, CB1-GP-Af530) was used in other on mouse samples at 1:100 (fig 2) and in immunohistochemistry on mouse samples at 1:500 (fig 1). Nat Commun (2015) ncbi
  • immunohistochemistry; rat; 1:3000
In order to study the expression of CB1 cannabinoid receptor in the ependyma of the rat spinal cord, Frontier Institute CB1 antibody (Frontier Sciences Institute, CB1-GP-Af530-1) was used in immunohistochemistry on rat samples at 1:3000. J Comp Neurol (2013) ncbi
Cayman Chemical
polyclonal
  • western blot; mouse; fig 6
In order to analyze prevention of BECN2-mediated drug tolerance to cannabioids by autophagy activation by novel inducers, Cayman Chemical CB1 antibody (Cayman Chemical, 101500) was used in western blot on mouse samples (fig 6). Autophagy (2016) ncbi
polyclonal
  • western blot; mouse; 1:200; fig 5
In order to determine if the hippocampal gene/protein expression of relevant glutamate signaling components, cannabinoid type 1 receptor, and endocannabinoid metabolic enzymes were altered following acute and/or repeated cocaine administration, Cayman Chemical CB1 antibody (Cayman, 101500) was used in western blot on mouse samples at 1:200 (fig 5). Eur Neuropsychopharmacol (2016) ncbi
Articles Reviewed
  1. Liu Z, Yang N, Dong J, Tian W, Chang L, Ma J, et al. Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction. Nat Commun. 2022;13:3490 pubmed publisher
  2. Swinton M, Sundermann E, Pedersen L, Nguyen J, Grelotti D, Taffe M, et al. Alterations in Brain Cannabinoid Receptor Levels Are Associated with HIV-Associated Neurocognitive Disorders in the ART Era: Implications for Therapeutic Strategies Targeting the Endocannabinoid System. Viruses. 2021;13: pubmed publisher
  3. Miller D, Wright K. Neuronal Dystroglycan regulates postnatal development of CCK/cannabinoid receptor-1 interneurons. Neural Dev. 2021;16:4 pubmed publisher
  4. Baranowska Kuczko M, Kozłowska H, Kloza M, Harasim Symbor E, Biernacki M, Kasacka I, et al. Beneficial Changes in Rat Vascular Endocannabinoid System in Primary Hypertension and under Treatment with Chronic Inhibition of Fatty Acid Amide Hydrolase by URB597. Int J Mol Sci. 2021;22: pubmed publisher
  5. Toschi A, Galiazzo G, Piva A, Tagliavia C, Mazzuoli Weber G, Chiocchetti R, et al. Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum. Animals (Basel). 2021;11: pubmed publisher
  6. Pelkey K, Calvigioni D, Fang C, Vargish G, Ekins T, Auville K, et al. Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons. elife. 2020;9: pubmed publisher
  7. Carceller H, Guirado R, Nacher J. Dark exposure affects plasticity-related molecules and interneurons throughout the visual system during adulthood. J Comp Neurol. 2019;: pubmed publisher
  8. Kuramoto K, Wang N, Fan Y, Zhang W, Schoenen F, Frankowski K, et al. Autophagy activation by novel inducers prevents BECN2-mediated drug tolerance to cannabinoids. Autophagy. 2016;12:1460-71 pubmed publisher
  9. Tomas Roig J, Wirths O, Salinas Riester G, Havemann Reinecke U. The Cannabinoid CB1/CB2 Agonist WIN55212.2 Promotes Oligodendrocyte Differentiation In Vitro and Neuroprotection During the Cuprizone-Induced Central Nervous System Demyelination. CNS Neurosci Ther. 2016;22:387-95 pubmed publisher
  10. Blanco E, Galeano P, Palomino A, Pavón F, Rivera P, Serrano A, et al. Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. Eur Neuropsychopharmacol. 2016;26:477-92 pubmed publisher
  11. Lowin T, Apitz M, Anders S, Straub R. Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner. Arthritis Res Ther. 2015;17:321 pubmed publisher
  12. Lenkey N, Kirizs T, Holderith N, Máté Z, Szabó G, Vizi E, et al. Tonic endocannabinoid-mediated modulation of GABA release is independent of the CB1 content of axon terminals. Nat Commun. 2015;6:6557 pubmed publisher
  13. Garcia Ovejero D, Arevalo Martin A, Paniagua Torija B, Sierra Palomares Y, Molina Holgado E. A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord. J Comp Neurol. 2013;521:233-51 pubmed publisher