This is a Validated Antibody Database (VAD) review about mouse C5ar1, based on 11 published articles (read how Labome selects the articles), using C5ar1 antibody in all methods. It is aimed to help Labome visitors find the most suited C5ar1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
C5ar1 synonym: C5aR; C5r1; Cd88; D7Msu1

BioLegend
rat monoclonal (20/70)
  • flow cytometry; mouse; loading ...; fig s2e
BioLegend C5ar1 antibody (Biolegend, 135809) was used in flow cytometry on mouse samples (fig s2e). Science (2019) ncbi
rat monoclonal (20/70)
  • flow cytometry; mouse; loading ...; fig 1a
BioLegend C5ar1 antibody (BioLegend, 20/70) was used in flow cytometry on mouse samples (fig 1a). J Clin Invest (2018) ncbi
rat monoclonal (20/70)
  • immunohistochemistry - frozen section; mouse; fig 5
BioLegend C5ar1 antibody (BioLegend, 135804) was used in immunohistochemistry - frozen section on mouse samples (fig 5). Gastroenterology (2015) ncbi
rat monoclonal (20/70)
  • flow cytometry; mouse; fig 2
BioLegend C5ar1 antibody (BioLegend, 20/70) was used in flow cytometry on mouse samples (fig 2). J Immunol (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (R63)
  • immunocytochemistry; human; fig 6d
Santa Cruz Biotechnology C5ar1 antibody (Santa Cruz, SC-53797) was used in immunocytochemistry on human samples (fig 6d). Toxins (Basel) (2017) ncbi
mouse monoclonal (S5/1)
  • western blot; human; loading ...; fig 1c
In order to investigate the contribution of NLRP3 inflammasome activity to the T helper cell 1 response, Santa Cruz Biotechnology C5ar1 antibody (Santa Cruz Biotechnology, sc-53795) was used in western blot on human samples (fig 1c). Science (2016) ncbi
LifeSpan Biosciences
rat monoclonal (20/70)
  • flow cytometry; mouse; fig 5
LifeSpan Biosciences C5ar1 antibody (LifeSpan Biosciences, 20/70) was used in flow cytometry on mouse samples (fig 5). J Immunol (2015) ncbi
Bio-Rad
rat monoclonal (20/70)
  • flow cytometry; mouse; fig 7
Bio-Rad C5ar1 antibody (AbD Serotec (Bio-Rad), 20/70) was used in flow cytometry on mouse samples (fig 7). J Immunol (2015) ncbi
BD Biosciences
rat monoclonal (20/70)
  • flow cytometry; mouse; loading ...; fig 6a
BD Biosciences C5ar1 antibody (BD, 20/70) was used in flow cytometry on mouse samples (fig 6a). Front Immunol (2019) ncbi
rat monoclonal (I52-1486)
  • blocking or activating experiments; mouse; loading ...; fig s4h
In order to find that coagulation factor XII modulates immune responses, BD Biosciences C5ar1 antibody (BD Biosciences, I52-1486) was used in blocking or activating experiments on mouse samples (fig s4h). Nat Commun (2016) ncbi
rat monoclonal (I52-278)
  • ELISA; mouse; 1:1000; fig 3
In order to determine how induced arthritis can be effectively treated by CTRP6, BD Biosciences C5ar1 antibody (BD Pharmingen, BD558028) was used in ELISA on mouse samples at 1:1000 (fig 3). Nat Commun (2015) ncbi
rat monoclonal (I52-1486)
  • ELISA; mouse; 1:1000; fig 3
In order to determine how induced arthritis can be effectively treated by CTRP6, BD Biosciences C5ar1 antibody (BD Pharmingen, BD558027) was used in ELISA on mouse samples at 1:1000 (fig 3). Nat Commun (2015) ncbi
Articles Reviewed
  1. Bell O, Copland D, Ward A, Nicholson L, Lange C, Chu C, et al. Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol. 2019;10:3033 pubmed publisher
  2. Chakarov S, Lim H, Tan L, Lim S, See P, Lum J, et al. Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches. Science. 2019;363: pubmed publisher
  3. Giles D, Duncker P, Wilkinson N, Washnock Schmid J, Segal B. CNS-resident classical DCs play a critical role in CNS autoimmune disease. J Clin Invest. 2018;128:5322-5334 pubmed publisher
  4. Gillman A, Breshears L, Kistler C, Finnegan P, Torres V, Schlievert P, et al. Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa. Toxins (Basel). 2017;9: pubmed publisher
  5. Arbore G, West E, Spolski R, Robertson A, Klos A, Rheinheimer C, et al. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells. Science. 2016;352:aad1210 pubmed publisher
  6. Göbel K, Pankratz S, Asaridou C, Herrmann A, Bittner S, Merker M, et al. Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. Nat Commun. 2016;7:11626 pubmed publisher
  7. Murayama M, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, et al. CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis. Nat Commun. 2015;6:8483 pubmed publisher
  8. Sendler M, Beyer G, Mahajan U, Kauschke V, Maertin S, Schurmann C, et al. Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis. Gastroenterology. 2015;149:765-76.e10 pubmed publisher
  9. Mehta G, Scheinman R, Holers V, Banda N. A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA. J Immunol. 2015;194:5446-54 pubmed publisher
  10. Sharma S, Chintala N, Vadrevu S, Patel J, Karbowniczek M, Markiewski M. Pulmonary alveolar macrophages contribute to the premetastatic niche by suppressing antitumor T cell responses in the lungs. J Immunol. 2015;194:5529-38 pubmed publisher
  11. Karsten C, Laumonnier Y, Eurich B, Ender F, Bröker K, Roy S, et al. Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse. J Immunol. 2015;194:1841-55 pubmed publisher