This is a Validated Antibody Database (VAD) review about mouse Brca1, based on 11 published articles (read how Labome selects the articles), using Brca1 antibody in all methods. It is aimed to help Labome visitors find the most suited Brca1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; human; fig s2
Abcam Brca1 antibody (Abcam, ab191042) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi
Invitrogen
mouse monoclonal (6B4)
  • immunocytochemistry knockout validation; mouse; 1:400; fig 6
  • western blot knockout validation; mouse; 1:1000; fig 5
  • immunocytochemistry; human; 1:400; fig 6
  • western blot; human; 1:1000; fig 5
In order to analyze telomere markers and alternative lengthening in BRCA1 defective cells, Invitrogen Brca1 antibody (Thermo Fisher, MA1-23164) was used in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 6), in western blot knockout validation on mouse samples at 1:1000 (fig 5), in immunocytochemistry on human samples at 1:400 (fig 6) and in western blot on human samples at 1:1000 (fig 5). Genes Chromosomes Cancer (2016) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 3b
Abcam Brca1 antibody (Abcam, ab191042) was used in western blot on rat samples (fig 3b). Redox Biol (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 1j, 1k
Abcam Brca1 antibody (Abcam, ab238983) was used in western blot on human samples at 1:1000 (fig 1j, 1k). Front Pharmacol (2021) ncbi
mouse monoclonal (MS110)
  • immunocytochemistry; human; loading ...; fig 1a
  • western blot; human; loading ...; fig 3a
Abcam Brca1 antibody (Abcam, MS110) was used in immunocytochemistry on human samples (fig 1a) and in western blot on human samples (fig 3a). Nucleic Acids Res (2019) ncbi
mouse monoclonal (MS110)
  • immunohistochemistry; human; loading ...; fig 8d
Abcam Brca1 antibody (Abcam, ab16780) was used in immunohistochemistry on human samples (fig 8d). Cell Death Differ (2019) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; human; fig s2
Abcam Brca1 antibody (Abcam, ab191042) was used in western blot knockout validation on human samples (fig s2). J Exp Clin Cancer Res (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:50; loading ...; fig 4a
Abcam Brca1 antibody (Abcam, ab191042) was used in immunohistochemistry on rat samples at 1:50 (fig 4a). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; mouse; fig 7
Abcam Brca1 antibody (Abcam, ab191042) was used in immunocytochemistry on mouse samples (fig 7). BMC Mol Biol (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 3b
Invitrogen Brca1 antibody (Invitrogen, PA5-97358) was used in western blot on rat samples (fig 3b). Redox Biol (2022) ncbi
mouse monoclonal (17F8)
  • ChIP-Seq; mouse; loading ...; fig 4a
Invitrogen Brca1 antibody (Thermo Fisher Scientific, 17F8) was used in ChIP-Seq on mouse samples (fig 4a). elife (2018) ncbi
mouse monoclonal (6B4)
  • immunocytochemistry knockout validation; mouse; 1:400; fig 6
  • western blot knockout validation; mouse; 1:1000; fig 5
  • immunocytochemistry; human; 1:400; fig 6
  • western blot; human; 1:1000; fig 5
In order to analyze telomere markers and alternative lengthening in BRCA1 defective cells, Invitrogen Brca1 antibody (Thermo Fisher, MA1-23164) was used in immunocytochemistry knockout validation on mouse samples at 1:400 (fig 6), in western blot knockout validation on mouse samples at 1:1000 (fig 5), in immunocytochemistry on human samples at 1:400 (fig 6) and in western blot on human samples at 1:1000 (fig 5). Genes Chromosomes Cancer (2016) ncbi
Aviva Systems Biology
  • immunohistochemistry - paraffin section; mouse
Aviva Systems Biology Brca1 antibody (Aviva System Biology, ARP33338_P050) was used in immunohistochemistry - paraffin section on mouse samples . Clin Cancer Res (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (247.56)
  • western blot; mouse; loading ...; fig 5g
Santa Cruz Biotechnology Brca1 antibody (Santa Cruz Biotechnology, sc-135731) was used in western blot on mouse samples (fig 5g). Development (2019) ncbi
Articles Reviewed
  1. Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, et al. BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance. Redox Biol. 2022;54:102356 pubmed publisher
  2. Hong H, Jin Z, Qian T, Xu X, Zhu X, Fei Q, et al. Falcarindiol Enhances Cisplatin Chemosensitivity of Hepatocellular Carcinoma via Down-Regulating the STAT3-Modulated PTTG1 Pathway. Front Pharmacol. 2021;12:656697 pubmed publisher
  3. Batenburg N, Walker J, Coulombe Y, Sherker A, Masson J, Zhu X. CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection. Nucleic Acids Res. 2019;47:10678-10692 pubmed publisher
  4. Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, et al. Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019;146: pubmed publisher
  5. Majumder K, Wang J, Boftsi M, Fuller M, Rede J, Joshi T, et al. Parvovirus minute virus of mice interacts with sites of cellular DNA damage to establish and amplify its lytic infection. elife. 2018;7: pubmed publisher
  6. Kim S, Jin H, Seo H, Lee H, Lee Y. Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation. Cell Death Differ. 2019;26:812-825 pubmed publisher
  7. Kargaran P, Yasaei H, Anjomani Virmouni S, Mangiapane G, Slijepcevic P. Analysis of alternative lengthening of telomere markers in BRCA1 defective cells. Genes Chromosomes Cancer. 2016;55:864-76 pubmed publisher
  8. Hamam D, Abdouh M, Gao Z, Arena V, Arena M, Arena G. Transfer of malignant trait to BRCA1 deficient human fibroblasts following exposure to serum of cancer patients. J Exp Clin Cancer Res. 2016;35:80 pubmed publisher
  9. Manchon J, DABAGHIAN Y, Uzor N, Kesler S, Wefel J, Tsvetkov A. Levetiracetam mitigates doxorubicin-induced DNA and synaptic damage in neurons. Sci Rep. 2016;6:25705 pubmed publisher
  10. Cao N, Li J, Rao Y, Liu H, Wu J, Li B, et al. A potential role for protein palmitoylation and zDHHC16 in DNA damage response. BMC Mol Biol. 2016;17:12 pubmed publisher
  11. Moiola C, De Luca P, Zalazar F, Cotignola J, Rodríguez Seguí S, Gardner K, et al. Prostate tumor growth is impaired by CtBP1 depletion in high-fat diet-fed mice. Clin Cancer Res. 2014;20:4086-95 pubmed publisher