This is a Validated Antibody Database (VAD) review about mouse Bmi1, based on 23 published articles (read how Labome selects the articles), using Bmi1 antibody in all methods. It is aimed to help Labome visitors find the most suited Bmi1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Bmi1 synonym: AW546694; Bmi-1; Pcgf4; polycomb complex protein BMI-1; B lymphoma Mo-MLV insertion region 1; polycomb group RING finger protein 4; polycomb group ring finger 4

Abcam
mouse monoclonal (F6)
  • western blot; human; loading ...; fig 3B
Abcam Bmi1 antibody (Abcam, ab14389) was used in western blot on human samples (fig 3B). Oncotarget (2016) ncbi
mouse monoclonal (F6)
  • chromatin immunoprecipitation; human; fig 4
Abcam Bmi1 antibody (Abcam, 14389) was used in chromatin immunoprecipitation on human samples (fig 4). Stem Cell Reports (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1a
Abcam Bmi1 antibody (Abcam, ab38295) was used in western blot on human samples (fig 1a). Leukemia (2016) ncbi
mouse monoclonal (F6)
  • western blot; human; loading ...; fig 1c
In order to study PCGF2, arsenic trioxide-induced PML-RARA protein degradation and UBE2I inhibition in NB4 cells, Abcam Bmi1 antibody (abcam, ab14389) was used in western blot on human samples (fig 1c). Biochim Biophys Acta (2016) ncbi
mouse monoclonal (F6)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
In order to determine the activation of PRC2, H3K27me3, and BMI1 in T and natural killer cell lymphomas, Abcam Bmi1 antibody (Abcam, 1.T.21) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Tumour Biol (2016) ncbi
rabbit polyclonal
  • western blot; human
Abcam Bmi1 antibody (Abcam, ab38295) was used in western blot on human samples . Int J Oncol (2015) ncbi
mouse monoclonal (F6)
  • western blot; human; 1:1000
Abcam Bmi1 antibody (Abcam, ab14389) was used in western blot on human samples at 1:1000. Carcinogenesis (2015) ncbi
rabbit polyclonal
  • western blot; mouse
Abcam Bmi1 antibody (Abcam, 38295) was used in western blot on mouse samples . J Reprod Dev (2015) ncbi
mouse monoclonal (F6)
  • chromatin immunoprecipitation; human; fig 3f
Abcam Bmi1 antibody (Abcam, ab14389) was used in chromatin immunoprecipitation on human samples (fig 3f). Nature (2014) ncbi
mouse monoclonal (F6)
  • ChIP-Seq; human
  • chromatin immunoprecipitation; human
Abcam Bmi1 antibody (Abcam, ab14389) was used in ChIP-Seq on human samples and in chromatin immunoprecipitation on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (F6)
  • immunohistochemistry - paraffin section; human
Abcam Bmi1 antibody (Abcam, ab14389) was used in immunohistochemistry - paraffin section on human samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100
Abcam Bmi1 antibody (Abcam, ab38295) was used in immunohistochemistry - paraffin section on human samples at 1:100. J Gastroenterol Hepatol (2014) ncbi
mouse monoclonal (F6)
  • chromatin immunoprecipitation; human
Abcam Bmi1 antibody (Abcam, ab14389) was used in chromatin immunoprecipitation on human samples . J Cell Mol Med (2014) ncbi
mouse monoclonal (F6)
  • immunohistochemistry - paraffin section; human; 1:100
Abcam Bmi1 antibody (Abcam, ab14389) was used in immunohistochemistry - paraffin section on human samples at 1:100. Cancer Med (2014) ncbi
mouse monoclonal (F6)
  • western blot; human; 1:1000
Abcam Bmi1 antibody (Abcam, ab14389) was used in western blot on human samples at 1:1000. PLoS ONE (2013) ncbi
rabbit polyclonal
  • western blot; human
In order to study the role of TWIST1 in the mechanism by which KLF17 induces epithelial-to-mesenchymal transition in endometrioid endometrial cancer, Abcam Bmi1 antibody (Abcam, ab38295) was used in western blot on human samples . Carcinogenesis (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:500
Abcam Bmi1 antibody (Abcam, ab38295) was used in immunohistochemistry - paraffin section on human samples at 1:500. J Neurol Sci (2013) ncbi
mouse monoclonal (F6)
  • immunocytochemistry; human
Abcam Bmi1 antibody (Abcam, ab14389) was used in immunocytochemistry on human samples . EMBO J (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100
  • immunohistochemistry - frozen section; human; 1:100
Abcam Bmi1 antibody (Abcam, ab38295) was used in immunohistochemistry - frozen section on mouse samples at 1:100 and in immunohistochemistry - frozen section on human samples at 1:100. Stem Cells (2013) ncbi
Cell Signaling Technology
rabbit monoclonal (D42B3)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology Bmi1 antibody (Cell Signaling Technology, 5856) was used in western blot on human samples (fig 3a). Cancer Res (2017) ncbi
rabbit monoclonal (D42B3)
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology Bmi1 antibody (Cell Signaling Technology, 5856) was used in western blot on human samples (fig 1d). J Biol Chem (2017) ncbi
rabbit monoclonal (D42B3)
  • western blot; mouse; fig 5
  • western blot; human; fig 6
Cell Signaling Technology Bmi1 antibody (Cell Signaling Tech, 5856) was used in western blot on mouse samples (fig 5) and in western blot on human samples (fig 6). Mol Cancer (2015) ncbi
rabbit monoclonal (D42B3)
  • immunohistochemistry - frozen section; mouse; fig 3
  • chromatin immunoprecipitation; mouse; fig 2
  • western blot; mouse; fig 2
Cell Signaling Technology Bmi1 antibody (Cell Signaling Technology, 5856) was used in immunohistochemistry - frozen section on mouse samples (fig 3), in chromatin immunoprecipitation on mouse samples (fig 2) and in western blot on mouse samples (fig 2). Aging Cell (2015) ncbi
Articles Reviewed
  1. Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
  2. Wheaton K, Sarkari F, Stanly Johns B, Davarinejad H, Egorova O, Kaustov L, et al. UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119. J Biol Chem. 2017;292:2893-2902 pubmed publisher
  3. Shan Z, Tian R, Zhang M, Gui Z, Wu J, Ding M, et al. miR128-1 inhibits the growth of glioblastoma multiforme and glioma stem-like cells via targeting BMI1 and E2F3. Oncotarget. 2016;7:78813-78826 pubmed publisher
  4. Kushwaha R, Jagadish N, Kustagi M, Mendiratta G, Seandel M, Soni R, et al. Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification. Stem Cell Reports. 2016;6:772-783 pubmed publisher
  5. Mariani S, Minieri V, De Dominici M, Iacobucci I, Peterson L, Calabretta B. CDKN2A-independent role of BMI1 in promoting growth and survival of Ph+ acute lymphoblastic leukemia. Leukemia. 2016;30:1682-90 pubmed publisher
  6. Jo S, Lee Y, Kim S, Lee H, Chung H. PCGF2 negatively regulates arsenic trioxide-induced PML-RARA protein degradation via UBE2I inhibition in NB4 cells. Biochim Biophys Acta. 2016;1863:1499-509 pubmed publisher
  7. Kim S, Yang W, Min Y, Ko Y, Yoon S. The role of the polycomb repressive complex pathway in T and NK cell lymphoma: biological and prognostic implications. Tumour Biol. 2016;37:2037-47 pubmed publisher
  8. Lee S, Litan A, Li Z, Graves B, Lindsey S, Barwe S, et al. Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity. Mol Cancer. 2015;14:159 pubmed publisher
  9. Galoian K, Qureshi A, D Ippolito G, Schiller P, Molinari M, Johnstone A, et al. Epigenetic regulation of embryonic stem cell marker miR302C in human chondrosarcoma as determinant of antiproliferative activity of proline-rich polypeptide 1. Int J Oncol. 2015;47:465-72 pubmed publisher
  10. Adhikary G, Grun D, Balasubramanian S, Kerr C, Huang J, Eckert R. Survival of skin cancer stem cells requires the Ezh2 polycomb group protein. Carcinogenesis. 2015;36:800-10 pubmed publisher
  11. Yamakoshi K, Katano S, Iida M, Kimura H, Okuma A, Ikemoto Uezumi M, et al. Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function. Aging Cell. 2015;14:616-24 pubmed publisher
  12. Chang B, Choi Y, Kim J. Collagen complexes increase the efficiency of iPS cells generated using fibroblasts from adult mice. J Reprod Dev. 2015;61:145-53 pubmed publisher
  13. Bhatnagar S, Gazin C, Chamberlain L, Ou J, Zhu X, Tushir J, et al. TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein. Nature. 2014;516:116-20 pubmed publisher
  14. Englert N, Luo G, Goldstein J, Surapureddi S. Epigenetic modification of histone 3 lysine 27: mediator subunit MED25 is required for the dissociation of polycomb repressive complex 2 from the promoter of cytochrome P450 2C9. J Biol Chem. 2015;290:2264-78 pubmed publisher
  15. Benard A, Goossens Beumer I, van Hoesel A, Horati H, Putter H, Zeestraten E, et al. Prognostic value of polycomb proteins EZH2, BMI1 and SUZ12 and histone modification H3K27me3 in colorectal cancer. PLoS ONE. 2014;9:e108265 pubmed publisher
  16. Ishikawa D, Shimada M, Utsunomiya T, Morine Y, Imura S, Ikemoto T, et al. Effect of Twist and Bmi1 on intraductal papillary mucinous neoplasm of the pancreas. J Gastroenterol Hepatol. 2014;29:2032-7 pubmed publisher
  17. Shen H, Chen Z, Ding X, Qi X, Cen J, Wang Y, et al. BMI1 reprogrammes histone acetylation and enhances c-fos pathway via directly binding to Zmym3 in malignant myeloid progression. J Cell Mol Med. 2014;18:1004-17 pubmed publisher
  18. Dalley A, Pitty L, Major A, Abdulmajeed A, Farah C. Expression of ABCG2 and Bmi-1 in oral potentially malignant lesions and oral squamous cell carcinoma. Cancer Med. 2014;3:273-83 pubmed publisher
  19. Adhikary G, Grun D, Kerr C, Balasubramanian S, Rorke E, Vemuri M, et al. Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation. PLoS ONE. 2013;8:e84324 pubmed publisher
  20. Dong P, Kaneuchi M, Xiong Y, Cao L, Cai M, Liu X, et al. Identification of KLF17 as a novel epithelial to mesenchymal transition inducer via direct activation of TWIST1 in endometrioid endometrial cancer. Carcinogenesis. 2014;35:760-8 pubmed publisher
  21. Wu Z, Wang Q, Wang L, Li G, Liu H, Fan F, et al. Combined aberrant expression of Bmi1 and EZH2 is predictive of poor prognosis in glioma patients. J Neurol Sci. 2013;335:191-6 pubmed publisher
  22. Martin N, Popov N, Aguilo F, O Loghlen A, Raguz S, Snijders A, et al. Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation. EMBO J. 2013;32:982-95 pubmed publisher
  23. Szabo A, Fong S, Yue L, Zhang K, Strachan L, Scalapino K, et al. The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability. Stem Cells. 2013;31:786-99 pubmed publisher