This is a Validated Antibody Database (VAD) review about mouse Arc, based on 22 published articles (read how Labome selects the articles), using Arc antibody in all methods. It is aimed to help Labome visitors find the most suited Arc antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Arc synonym: Arc3.1; C86064; arg3.1; mArc

Santa Cruz Biotechnology
mouse monoclonal (C-7)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 7a
Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc-17839) was used in immunohistochemistry on mouse samples at 1:100 (fig 7a). Eneuro (2021) ncbi
mouse monoclonal (C-7)
  • western blot; rat; loading ...; fig 6a
Santa Cruz Biotechnology Arc antibody (Santa Cruz Biotechnology, sc-17839) was used in western blot on rat samples (fig 6a). Front Behav Neurosci (2020) ncbi
mouse monoclonal (C-7)
  • immunohistochemistry - free floating section; mouse; 1:200; loading ...; fig 1i
Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc-17839) was used in immunohistochemistry - free floating section on mouse samples at 1:200 (fig 1i). Nat Commun (2019) ncbi
mouse monoclonal (A-7)
  • western blot; mouse; loading ...; fig 2d
Santa Cruz Biotechnology Arc antibody (Santa Cruz Biotechnology, sc-166461) was used in western blot on mouse samples (fig 2d). Transl Psychiatry (2019) ncbi
mouse monoclonal (C-7)
Santa Cruz Biotechnology Arc antibody (SantaCruz, sc-17839) was used . Cell (2018) ncbi
mouse monoclonal (40)
  • western blot; mouse; loading ...; fig 4e
In order to study the roll of a mammalian circular RNA locus in miRNA homeostasis and brain function, Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc-136278) was used in western blot on mouse samples (fig 4e). Science (2017) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; loading ...; fig 13
In order to show that PTI-125 therapeutically alters filamin A and reverses proteopathy, Santa Cruz Biotechnology Arc antibody (SantaCruz, SC-17839) was used in western blot on mouse samples (fig 13). Neurobiol Aging (2017) ncbi
mouse monoclonal (C-7)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 3i
In order to discover that repeated exposure of striatal GABAergic spiny projecting neurons to D-amphetamine decreases global striatal mRNA translation, Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc17839) was used in immunohistochemistry on mouse samples at 1:500 (fig 3i). Front Mol Neurosci (2016) ncbi
mouse monoclonal (C-7)
  • immunohistochemistry; mouse; loading ...; fig 5f
In order to evaluate host immune-mediated cell rejection in a retinal transplantation model, Santa Cruz Biotechnology Arc antibody (Santa Cruz, SC-17839) was used in immunohistochemistry on mouse samples (fig 5f). Cell Stem Cell (2017) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; loading ...; fig 6b
In order to explore the role of hippocampal T cell infiltration in tau-driven pathophysiology and cognitive impairments, Santa Cruz Biotechnology Arc antibody (SantaCruz, sc17839) was used in western blot on mouse samples (fig 6b). Brain (2017) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; 1:1000; fig 1
Santa Cruz Biotechnology Arc antibody (santa Cruz, sc-17839) was used in western blot on mouse samples at 1:1000 (fig 1). Sci Rep (2016) ncbi
mouse monoclonal (H-6)
  • immunocytochemistry; mouse; 1:100; fig 2
In order to study Brd4 function in the brain, Santa Cruz Biotechnology Arc antibody (Santa Cruz, 365736) was used in immunocytochemistry on mouse samples at 1:100 (fig 2). Nat Neurosci (2015) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; 1:200
In order to establish a method to directly control specific protein production in response to chemicals, Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc-17839) was used in western blot on mouse samples at 1:200. Nat Chem Biol (2015) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; fig 2b
Santa Cruz Biotechnology Arc antibody (Santa Cruz Biotechnology, SC-17839) was used in western blot on mouse samples (fig 2b). J Neurochem (2015) ncbi
mouse monoclonal (C-7)
  • immunohistochemistry - free floating section; mouse; 1:200
Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc-17839) was used in immunohistochemistry - free floating section on mouse samples at 1:200. Mol Psychiatry (2016) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; 1:1000; loading ...; fig 2b
Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc 17839) was used in western blot on mouse samples at 1:1000 (fig 2b). Int J Neuropsychopharmacol (2014) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; 1:1000
Santa Cruz Biotechnology Arc antibody (Santa Cruz Biotechnology, sc-17839) was used in western blot on mouse samples at 1:1000. J Neurosci (2015) ncbi
mouse monoclonal (C-7)
  • western blot; rat; 1:250
Santa Cruz Biotechnology Arc antibody (Santa Cruz, C7) was used in western blot on rat samples at 1:250. Neurobiol Learn Mem (2014) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; 1:1000
Santa Cruz Biotechnology Arc antibody (Santa Cruz, sc-17839) was used in western blot on mouse samples at 1:1000. Neurobiol Learn Mem (2014) ncbi
mouse monoclonal (C-7)
  • western blot; mouse; 1:500
Santa Cruz Biotechnology Arc antibody (Santa Cruz Biotechnology, sc-17839) was used in western blot on mouse samples at 1:500. Nat Med (2013) ncbi
mouse monoclonal (C-7)
  • western blot; rat; 1:200; fig 1
  • western blot; mouse; 1:200; fig 5
Santa Cruz Biotechnology Arc antibody (Santa Cruz Biotechnology, sc-17839) was used in western blot on rat samples at 1:200 (fig 1) and in western blot on mouse samples at 1:200 (fig 5). Sci Rep (2013) ncbi
mouse monoclonal (C-7)
  • immunohistochemistry - free floating section; rat; 1:100
Santa Cruz Biotechnology Arc antibody (Santa Cruz Biotechnology, sc-17839) was used in immunohistochemistry - free floating section on rat samples at 1:100. J Neurochem (2014) ncbi
Articles Reviewed
  1. Åmellem I, Yovianto G, Chong H, Nair R, Cnops V, Thanawalla A, et al. Role of NMDA Receptors in Adult Neurogenesis and Normal Development of the Dentate Gyrus. Eneuro. 2021;8: pubmed publisher
  2. Sanna F, Bratzu J, Serra M, Leo D, Quartu M, Boi M, et al. Altered Sexual Behavior in Dopamine Transporter (DAT) Knockout Male Rats: A Behavioral, Neurochemical and Intracerebral Microdialysis Study. Front Behav Neurosci. 2020;14:58 pubmed publisher
  3. Rao Ruiz P, Couey J, Marcelo I, Bouwkamp C, Slump D, Matos M, et al. Engram-specific transcriptome profiling of contextual memory consolidation. Nat Commun. 2019;10:2232 pubmed publisher
  4. Huang C, Muszynski K, Bolshakov V, Balu D. Deletion of Dtnbp1 in mice impairs threat memory consolidation and is associated with enhanced inhibitory drive in the amygdala. Transl Psychiatry. 2019;9:132 pubmed publisher
  5. Pastuzyn E, Day C, Kearns R, Kyrke Smith M, Taibi A, McCormick J, et al. The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer. Cell. 2018;172:275-288.e18 pubmed publisher
  6. Piwecka M, Glažar P, Hernández Miranda L, Memczak S, Wolf S, Rybak Wolf A, et al. Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function. Science. 2017;357: pubmed publisher
  7. Wang H, Lee K, Pei Z, Khan A, Bakshi K, Burns L. PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis. Neurobiol Aging. 2017;55:99-114 pubmed publisher
  8. Biever A, Boubaker Vitre J, Cutando L, Gracia Rubio I, Costa Mattioli M, Puighermanal E, et al. Repeated Exposure to D-Amphetamine Decreases Global Protein Synthesis and Regulates the Translation of a Subset of mRNAs in the Striatum. Front Mol Neurosci. 2016;9:165 pubmed publisher
  9. Zhu J, Cifuentes H, Reynolds J, Lamba D. Immunosuppression via Loss of IL2rγ Enhances Long-Term Functional Integration of hESC-Derived Photoreceptors in the Mouse Retina. Cell Stem Cell. 2017;20:374-384.e5 pubmed publisher
  10. Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher
  11. Nakayama D, Hashikawa Yamasaki Y, Ikegaya Y, Matsuki N, Nomura H. Late Arc/Arg3.1 expression in the basolateral amygdala is essential for persistence of newly-acquired and reactivated contextual fear memories. Sci Rep. 2016;6:21007 pubmed publisher
  12. Korb E, Herre M, Zucker Scharff I, Darnell R, Allis C. BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice. Nat Neurosci. 2015;18:1464-73 pubmed publisher
  13. Chung H, Jacobs C, Huo Y, Yang J, Krumm S, Plemper R, et al. Tunable and reversible drug control of protein production via a self-excising degron. Nat Chem Biol. 2015;11:713-20 pubmed publisher
  14. Singh P, Konar A, Kumar A, Srivas S, Thakur M. Hippocampal chromatin-modifying enzymes are pivotal for scopolamine-induced synaptic plasticity gene expression changes and memory impairment. J Neurochem. 2015;134:642-51 pubmed publisher
  15. Gouty Colomer L, Hosseini B, Marcelo I, Schreiber J, Slump D, Yamaguchi S, et al. Arc expression identifies the lateral amygdala fear memory trace. Mol Psychiatry. 2016;21:364-75 pubmed publisher
  16. Subbanna S, Nagre N, Umapathy N, Pace B, Basavarajappa B. Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing neurobehavioral abnormalities in adult mice. Int J Neuropsychopharmacol. 2014;18: pubmed publisher
  17. Nakayama D, Iwata H, Teshirogi C, Ikegaya Y, Matsuki N, Nomura H. Long-delayed expression of the immediate early gene Arc/Arg3.1 refines neuronal circuits to perpetuate fear memory. J Neurosci. 2015;35:819-30 pubmed publisher
  18. Fletcher B, Hill G, Long J, Gallagher M, Shapiro M, Rapp P. A fine balance: Regulation of hippocampal Arc/Arg3.1 transcription, translation and degradation in a rat model of normal cognitive aging. Neurobiol Learn Mem. 2014;115:58-67 pubmed publisher
  19. Wang Z, Park S, Zhao H, Peng S, Zuo Z. A critical role of glutamate transporter type 3 in the learning and memory of mice. Neurobiol Learn Mem. 2014;114:70-80 pubmed publisher
  20. Udagawa T, Farny N, Jakovcevski M, Kaphzan H, Alarcon J, Anilkumar S, et al. Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology. Nat Med. 2013;19:1473-7 pubmed publisher
  21. Whittington R, Bretteville A, Virag L, Emala C, Maurin T, Marcouiller F, et al. Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation. Sci Rep. 2013;3:1388 pubmed publisher
  22. Liu Q, Rubio F, Bossert J, Marchant N, Fanous S, Hou X, et al. Detection of molecular alterations in methamphetamine-activated Fos-expressing neurons from a single rat dorsal striatum using fluorescence-activated cell sorting (FACS). J Neurochem. 2014;128:173-85 pubmed publisher