This is a Validated Antibody Database (VAD) review about mouse Appl1, based on 7 published articles (read how Labome selects the articles), using Appl1 antibody in all methods. It is aimed to help Labome visitors find the most suited Appl1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Appl1 synonym: 2900057D21Rik; 7330406P05Rik; AI585782; AW209077; BB022931; C88264; DIP13; DCC-interacting protein 13-alpha; DIP13 alpha; adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein APPL like; dip13-alpha

Cell Signaling Technology
rabbit monoclonal (D83H4)
  • western blot; human; 1:1000; loading ...; fig ex1m
Cell Signaling Technology Appl1 antibody (Cell Signaling, 3858S) was used in western blot on human samples at 1:1000 (fig ex1m). Nature (2018) ncbi
rabbit monoclonal (D83H4)
  • western blot; human; 1:1000; fig 4a
Cell Signaling Technology Appl1 antibody (Cell Signaling, 3858) was used in western blot on human samples at 1:1000 (fig 4a). PLoS ONE (2017) ncbi
rabbit monoclonal (D83H4)
  • immunohistochemistry; rat; fig 2a
Cell Signaling Technology Appl1 antibody (Cell Signalling Technology, 3858) was used in immunohistochemistry on rat samples (fig 2a). J Cell Sci (2016) ncbi
rabbit monoclonal (D83H4)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 2
Cell Signaling Technology Appl1 antibody (Cell Signaling Tech, 3858) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 2). EMBO J (2015) ncbi
rabbit monoclonal (D83H4)
  • western blot; mouse; 1:1000; fig s6
Cell Signaling Technology Appl1 antibody (Cell signaling, 3858) was used in western blot on mouse samples at 1:1000 (fig s6). Nat Commun (2015) ncbi
rabbit monoclonal (D83H4)
  • immunocytochemistry; human; 10 ug/ml; fig s7
In order to elucidate the role of COMMD1 in copper homeostasis, Cell Signaling Technology Appl1 antibody (Cell Signaling Technology, 3858S) was used in immunocytochemistry on human samples at 10 ug/ml (fig s7). Mol Biol Cell (2015) ncbi
rabbit monoclonal (D83H4)
  • western blot; rat
Cell Signaling Technology Appl1 antibody (Cell Signaling, 3858S) was used in western blot on rat samples . Am J Physiol Regul Integr Comp Physiol (2012) ncbi
Articles Reviewed
  1. Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed publisher
  2. Jung Y, Lee J, Sohn K, Lee Y, Seo Y, Kim C, et al. Adiponectin Signaling Regulates Lipid Production in Human Sebocytes. PLoS ONE. 2017;12:e0169824 pubmed publisher
  3. Fernandez Monreal M, Sánchez Castillo C, Esteban J. APPL1 gates long-term potentiation through its plekstrin homology domain. J Cell Sci. 2016;129:2793-803 pubmed publisher
  4. Reis C, Chen P, Srinivasan S, Aguet F, Mettlen M, Schmid S. Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J. 2015;34:2132-46 pubmed publisher
  5. Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher
  6. Phillips Krawczak C, Singla A, Starokadomskyy P, Deng Z, Osborne D, Li H, et al. COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. Mol Biol Cell. 2015;26:91-103 pubmed publisher
  7. Gulli R, Tishinsky J, Macdonald T, Robinson L, Wright D, Dyck D. Exercise restores insulin, but not adiponectin, response in skeletal muscle of high-fat fed rodents. Am J Physiol Regul Integr Comp Physiol. 2012;303:R1062-70 pubmed publisher