This is a Validated Antibody Database (VAD) review about mouse Apc, based on 33 published articles (read how Labome selects the articles), using Apc antibody in all methods. It is aimed to help Labome visitors find the most suited Apc antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Apc synonym: AI047805; AU020952; AW124434; CC1; Min; mAPC

Abcam
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 8f
Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 8f). elife (2019) ncbi
domestic rabbit polyclonal
  • western blot; brown rat; 1:2000; loading ...; fig 2b
Abcam Apc antibody (Abcam, ab15270) was used in western blot on brown rat samples at 1:2000 (fig 2b). Biosci Rep (2019) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry; brown rat; 1:50; loading ...; fig s1c
Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry on brown rat samples at 1:50 (fig s1c). Cell Death Differ (2018) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry; brown rat; 1:100; loading ...; fig 5
Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry on brown rat samples at 1:100 (fig 5). J Histochem Cytochem (2018) ncbi
mouse monoclonal (CC-1)
  • immunocytochemistry; mouse; 1:200; loading ...; fig 3e
Abcam Apc antibody (Abcam, ab16794) was used in immunocytochemistry on mouse samples at 1:200 (fig 3e). Stem Cell Reports (2017) ncbi
mouse monoclonal (CC-1)
  • immunocytochemistry; human; 1:300; loading ...; fig 2a
  • western blot; human; 1:1000; loading ...; fig 2b
  • immunoprecipitation; brown rat; loading ...; fig 1b
  • western blot; brown rat; 1:1000; loading ...; fig 1b
  • immunohistochemistry; mouse; 1:300; loading ...; fig 3a
In order to demonstrate that the CC1 antibody binds Quaking 7 in myelinating oligodendrocytes, Abcam Apc antibody (AbCam, 16794) was used in immunocytochemistry on human samples at 1:300 (fig 2a), in western blot on human samples at 1:1000 (fig 2b), in immunoprecipitation on brown rat samples (fig 1b), in western blot on brown rat samples at 1:1000 (fig 1b) and in immunohistochemistry on mouse samples at 1:300 (fig 3a). J Neurochem (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - free floating section; brown rat; 1:100; fig 5
Abcam Apc antibody (Abcam, Ab16794) was used in immunohistochemistry - free floating section on brown rat samples at 1:100 (fig 5). Brain (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 3a
In order to investigate the link between chronic stress and NG2 positive cell maturation and myelination, Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 3a). Exp Neurol (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:200; fig 1
Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 1). Stem Cell Reports (2016) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - paraffin section; brown rat; 1:1000
Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - paraffin section on brown rat samples at 1:1000. Cell Death Dis (2015) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 2
In order to analyze the process of neuronal cell death after traumatic brain injury due to impaired autophagy flux, Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 2). Autophagy (2014) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - paraffin section; mouse
Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - paraffin section on mouse samples . J Neurosci (2014) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; mouse; 1:20
In order to use a SIP1-EGFP reporter mouse to study brain development, Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on mouse samples at 1:20. Genesis (2014) ncbi
mouse monoclonal (CC-1)
  • immunohistochemistry - frozen section; brown rat; 1:400
Abcam Apc antibody (Abcam, ab16794) was used in immunohistochemistry - frozen section on brown rat samples at 1:400. J Comp Neurol (2008) ncbi
Invitrogen
mouse monoclonal (eBio25-D1.16 (25-D1.16))
  • flow cytometry; mouse; loading ...; fig 4a
Invitrogen Apc antibody (eBioscience, 17-5743) was used in flow cytometry on mouse samples (fig 4a). Cell (2019) ncbi
mouse monoclonal (eBio25-D1.16 (25-D1.16))
  • flow cytometry; mouse; 1:200; fig 4
Invitrogen Apc antibody (eBiosciences, 17-5743) was used in flow cytometry on mouse samples at 1:200 (fig 4). PLoS ONE (2016) ncbi
mouse monoclonal (eBio25-D1.16 (25-D1.16))
  • flow cytometry; human
  • immunocytochemistry; human; fig 3
Invitrogen Apc antibody (eBioscience, 17-5743-82) was used in flow cytometry on human samples and in immunocytochemistry on human samples (fig 3). J Immunol (2014) ncbi
mouse monoclonal (eBio25-D1.16 (25-D1.16))
  • flow cytometry; mouse; fig 1
In order to optimize the CD8 T cell-inducing capacity of modified vaccinia Ankara, Invitrogen Apc antibody (eBioscience, 25-D1.16) was used in flow cytometry on mouse samples (fig 1). Front Immunol (2013) ncbi
mouse monoclonal (T3.70)
  • flow cytometry; mouse; fig 8
In order to investigate how bystander CD8 cells are impacted during viral infection, Invitrogen Apc antibody (eBioscience, T3.70) was used in flow cytometry on mouse samples (fig 8). J Immunol (2010) ncbi
Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; fig 1d
In order to investigate the role of growth hormone in colon cancer, Santa Cruz Biotechnology Apc antibody (Santa Cruz, sc-393704) was used in western blot on human samples (fig 1d). Proc Natl Acad Sci U S A (2016) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • immunoprecipitation; human; 1:100; loading ...; fig 4h, 5a, 5b
Cell Signaling Technology Apc antibody (Cell Signaling, 2504S) was used in immunoprecipitation on human samples at 1:100 (fig 4h, 5a, 5b). Mol Cell (2018) ncbi
EMD Millipore
mouse monoclonal
  • western blot; human; 1:500; loading ...; fig 4h, 5a, 5b
EMD Millipore Apc antibody (MilliporeSigma, OP44) was used in western blot on human samples at 1:500 (fig 4h, 5a, 5b). Mol Cell (2018) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 2e
EMD Millipore Apc antibody (Calbiochem, OP80-100) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 2e). elife (2017) ncbi
mouse monoclonal
  • western blot; human; 1:1000; fig 3
EMD Millipore Apc antibody (Calbiochem, op44) was used in western blot on human samples at 1:1000 (fig 3). J Clin Endocrinol Metab (2016) ncbi
mouse monoclonal
  • western blot; mouse; 1:100; fig 5
  • western blot; human; 1:100; fig 1
In order to report a role for adenomatous polyposis coli in the transport of mitochondria, EMD Millipore Apc antibody (Merck, OP44) was used in western blot on mouse samples at 1:100 (fig 5) and in western blot on human samples at 1:100 (fig 1). Mol Biol Cell (2016) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; mouse; 1:50; fig 8
In order to elucidate the mechanisms by which increased LMNB1 levels cause autosomal dominant leukodystrophy, EMD Millipore Apc antibody (Calbiochem, OP-80) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 8). J Neurosci (2015) ncbi
mouse monoclonal
  • immunohistochemistry; mouse; 1:50
EMD Millipore Apc antibody (CalBiochem, OP80-100UG) was used in immunohistochemistry on mouse samples at 1:50. J Neurosci (2015) ncbi
mouse monoclonal
  • immunohistochemistry - free floating section; mouse; 1:400
In order to assess using recombinant adeno-associated virus rhesus-10 as a gene therapy vector in the central nervous system, EMD Millipore Apc antibody (EMD Bioscience, OP80-100UG) was used in immunohistochemistry - free floating section on mouse samples at 1:400. Mol Neurobiol (2016) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; brown rat; 1:400
In order to characterize the incidence, distribution, and cellular composition of the ectopic colonies arising from transplanted fetal neuronal stem cells in the nervous system, EMD Millipore Apc antibody (EMD Millipore, OP-80) was used in immunohistochemistry - frozen section on brown rat samples at 1:400. J Neurosci (2014) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; mouse; 1:50
EMD Millipore Apc antibody (EMD Biosciences, OP80-100UG) was used in immunohistochemistry - frozen section on mouse samples at 1:50. J Neurosci (2014) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; brown rat; 1:400
In order to evaluate the long distance growth and connectivity of neural stem cells after neural stem cell transplantation, EMD Millipore Apc antibody (Oncogene, OP80-100UG) was used in immunohistochemistry - frozen section on brown rat samples at 1:400. Exp Neurol (2014) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; brown rat; 1:200
EMD Millipore Apc antibody (Millipore, OP80-100UG) was used in immunohistochemistry - frozen section on brown rat samples at 1:200. J Comp Neurol (2014) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; mouse; 1:200
EMD Millipore Apc antibody (EMD, OP80-100UG) was used in immunohistochemistry - frozen section on mouse samples at 1:200. Hum Mol Genet (2014) ncbi
mouse monoclonal
  • immunohistochemistry - free floating section; mouse; 1:40
  • immunocytochemistry; mouse; 1:200
EMD Millipore Apc antibody (Millipore, OP-80) was used in immunohistochemistry - free floating section on mouse samples at 1:40 and in immunocytochemistry on mouse samples at 1:200. J Neurosci (2013) ncbi
Articles Reviewed
  1. Stedehouder J, Brizee D, Slotman J, Pascual Garcia M, Leyrer M, Bouwen B, et al. Local axonal morphology guides the topography of interneuron myelination in mouse and human neocortex. elife. 2019;8: pubmed publisher
  2. Miao Y, Yang H, Levorse J, Yuan S, Polak L, Sribour M, et al. Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells. Cell. 2019;177:1172-1186.e14 pubmed publisher
  3. Lai X, Deng Z, Zhu X, Chen Z. Apc gene suppresses intracranial aneurysm formation and rupture through inhibiting the NF-κB signaling pathway mediated inflammatory response. Biosci Rep. 2019;39: pubmed publisher
  4. Ji L, Lu B, Wang Z, Yang Z, Reece Hoyes J, Russ C, et al. Identification of ICAT as an APC Inhibitor, Revealing Wnt-Dependent Inhibition of APC-Axin Interaction. Mol Cell. 2018;72:37-47.e4 pubmed publisher
  5. Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, et al. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke. Cell Death Differ. 2018;25:1503-1516 pubmed publisher
  6. Wang Y, Lin Y, Wu Y, Yao Z, Tang J, Shen L, et al. Expression and Cellular Localization of IFITM1 in Normal and Injured Rat Spinal Cords. J Histochem Cytochem. 2018;66:175-187 pubmed publisher
  7. Itakura G, Kawabata S, Ando M, Nishiyama Y, Sugai K, Ozaki M, et al. Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives. Stem Cell Reports. 2017;8:673-684 pubmed publisher
  8. Lischinsky J, Sokolowski K, Li P, Esumi S, Kamal Y, Goodrich M, et al. Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues. elife. 2017;6: pubmed publisher
  9. Fotouhi O, Kjellin H, Larsson C, Hashemi J, Barriuso J, Juhlin C, et al. Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors. J Clin Endocrinol Metab. 2016;101:3616-3627 pubmed
  10. Bin J, Harris S, Kennedy T. The oligodendrocyte-specific antibody 'CC1' binds Quaking 7. J Neurochem. 2016;139:181-186 pubmed publisher
  11. Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher
  12. Martin S, Brown S, Wick D, Nielsen J, Kroeger D, Twumasi Boateng K, et al. Low Mutation Burden in Ovarian Cancer May Limit the Utility of Neoantigen-Targeted Vaccines. PLoS ONE. 2016;11:e0155189 pubmed publisher
  13. Delbary Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, et al. A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. Brain. 2016;139:1762-82 pubmed publisher
  14. Yang Y, Zhang Y, Luo F, Li B. Chronic stress regulates NG2⁺ cell maturation and myelination in the prefrontal cortex through induction of death receptor 6. Exp Neurol. 2016;277:202-214 pubmed publisher
  15. Kawabata S, Takano M, Numasawa Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, et al. Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury. Stem Cell Reports. 2016;6:1-8 pubmed publisher
  16. Mills K, Brocardo M, Henderson B. APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane. Mol Biol Cell. 2016;27:466-82 pubmed publisher
  17. Rolyan H, Tyurina Y, Hernandez M, Amoscato A, Sparvero L, Nmezi B, et al. Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. J Neurosci. 2015;35:12002-17 pubmed publisher
  18. Kraushar M, Viljetić B, Wijeratne H, Thompson K, Jiao X, Pike J, et al. Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes. J Neurosci. 2015;35:10911-26 pubmed publisher
  19. Guo Y, Wang D, Qiao T, Yang C, Su Q, Gao G, et al. A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord. Mol Neurobiol. 2016;53:3235-3248 pubmed publisher
  20. Liu S, Sarkar C, Dinizo M, Faden A, Koh E, Lipinski M, et al. Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death. Cell Death Dis. 2015;6:e1582 pubmed publisher
  21. Sarkar C, Zhao Z, Aungst S, Sabirzhanov B, Faden A, Lipinski M. Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury. Autophagy. 2014;10:2208-22 pubmed publisher
  22. Steward O, Sharp K, Yee K, Hatch M, Bonner J. Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury. J Neurosci. 2014;34:14013-21 pubmed publisher
  23. Lin Y, Pang X, Huang G, Jamison S, Fang J, Harding H, et al. Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice. J Neurosci. 2014;34:12182-91 pubmed publisher
  24. Bull S, Bin J, Beaumont E, Boutet A, Krimpenfort P, Sadikot A, et al. Progressive disorganization of paranodal junctions and compact myelin due to loss of DCC expression by oligodendrocytes. J Neurosci. 2014;34:9768-78 pubmed publisher
  25. Sharp K, Yee K, Steward O. A re-assessment of long distance growth and connectivity of neural stem cells after severe spinal cord injury. Exp Neurol. 2014;257:186-204 pubmed publisher
  26. Sevc J, Matiašová A, Kútna V, Daxnerova Z. Evidence that the central canal lining of the spinal cord contributes to oligodendrogenesis during postnatal development and adulthood in intact rats. J Comp Neurol. 2014;522:3194-207 pubmed publisher
  27. Ramakrishnan R, Tyurin V, Tuyrin V, Veglia F, Condamine T, Amoscato A, et al. Oxidized lipids block antigen cross-presentation by dendritic cells in cancer. J Immunol. 2014;192:2920-31 pubmed publisher
  28. Nishizaki Y, Takagi T, Matsui F, Higashi Y. SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Genesis. 2014;52:56-67 pubmed publisher
  29. Wang H, Yang B, Qiu L, Yang C, Kramer J, Su Q, et al. Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis. Hum Mol Genet. 2014;23:668-81 pubmed publisher
  30. Lauterbach H, Pätzold J, Kassub R, Bathke B, Brinkmann K, Chaplin P, et al. Genetic Adjuvantation of Recombinant MVA with CD40L Potentiates CD8 T Cell Mediated Immunity. Front Immunol. 2013;4:251 pubmed publisher
  31. Chen C, Sloane J, Li H, Aytan N, Giannaris E, Zeldich E, et al. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013;33:1927-39 pubmed publisher
  32. Marshall H, Prince A, Berg L, Welsh R. IFN-alpha beta and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol. 2010;185:1419-28 pubmed publisher
  33. Tripathi R, McTigue D. Chronically increased ciliary neurotrophic factor and fibroblast growth factor-2 expression after spinal contusion in rats. J Comp Neurol. 2008;510:129-44 pubmed publisher