This is a Validated Antibody Database (VAD) review about mouse Aim2, based on 4 published articles (read how Labome selects the articles), using Aim2 antibody in all methods. It is aimed to help Labome visitors find the most suited Aim2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Aim2 synonym: Gm1313; Ifi210; interferon-inducible protein AIM2; ifi-210; interferon-inducible protein 210; interferon-inducible protein p210

Knockout validation
Abcam
rabbit polyclonal
  • western blot knockout validation; human; fig 2a
Abcam Aim2 antibody (Abcam, ab93015) was used in western blot knockout validation on human samples (fig 2a). MBio (2019) ncbi
Abcam
rabbit polyclonal
  • western blot knockout validation; human; fig 2a
Abcam Aim2 antibody (Abcam, ab93015) was used in western blot knockout validation on human samples (fig 2a). MBio (2019) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig 1a
Abcam Aim2 antibody (Abcam, ab93015) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Oncotarget (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human
  • western blot; human; 1:200
Abcam Aim2 antibody (Abcam, ab93015) was used in immunohistochemistry on human samples and in western blot on human samples at 1:200. Mediators Inflamm (2014) ncbi
Invitrogen
rabbit polyclonal
  • western blot; human; loading ...; fig 2d
In order to study inflammasome activation during primary Epstein-Barr virus infection, Invitrogen Aim2 antibody (eBioscience, 14-6008) was used in western blot on human samples (fig 2d). PLoS ONE (2017) ncbi
Articles Reviewed
  1. Botto S, Abraham J, Mizuno N, Pryke K, Gall B, Landais I, et al. Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome. MBio. 2019;10: pubmed publisher
  2. Torii Y, Kawada J, Murata T, Yoshiyama H, Kimura H, Ito Y. Epstein-Barr virus infection-induced inflammasome activation in human monocytes. PLoS ONE. 2017;12:e0175053 pubmed publisher
  3. Ma X, Guo P, Qiu Y, Mu K, Zhu L, Zhao W, et al. Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway. Oncotarget. 2016;7:36185-36197 pubmed publisher
  4. Zhen J, Zhang L, Pan J, Ma S, Yu X, Li X, et al. AIM2 mediates inflammation-associated renal damage in hepatitis B virus-associated glomerulonephritis by regulating caspase-1, IL-1?, and IL-18. Mediators Inflamm. 2014;2014:190860 pubmed publisher