This is a Validated Antibody Database (VAD) review about mouse Aifm1, based on 30 published articles (read how Labome selects the articles), using Aifm1 antibody in all methods. It is aimed to help Labome visitors find the most suited Aifm1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Aifm1 synonym: AIF; AIFsh2; Hq; Pdcd8

Santa Cruz Biotechnology
mouse monoclonal (E-1)
  • western blot; human; 1:1000; loading ...; fig 4b
Santa Cruz Biotechnology Aifm1 antibody (Santa, sc-13116) was used in western blot on human samples at 1:1000 (fig 4b). EMBO Mol Med (2019) ncbi
mouse monoclonal (E-1)
  • western blot; human; fig 1b
In order to show the role of Pex3 and Pex14 in generating human peroxisomes, Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz, sc-13116) was used in western blot on human samples (fig 1b). Nature (2017) ncbi
mouse monoclonal (E-1)
  • western blot; human; 1:700; loading ...; fig 4a
Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz, sc-13116) was used in western blot on human samples at 1:700 (fig 4a). Oncotarget (2016) ncbi
mouse monoclonal (E-1)
  • western blot; human; fig 2
In order to analyze control of AIF-dependent growth support in pancreatic cancer cells by basal metabolic state, Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz Biotechnology, sc-13116) was used in western blot on human samples (fig 2). BMC Cancer (2016) ncbi
mouse monoclonal (E-1)
  • western blot; human; fig s8
In order to study the support of redox homeostasis during anchorage-independent growth by reductive carboxylation, Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz, sc-13116) was used in western blot on human samples (fig s8). Nature (2016) ncbi
mouse monoclonal (E-1)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Aifm1 antibody (SCBT, E-1) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (E-1)
  • western blot; mouse; fig 6
  • western blot; brown rat; fig 2
Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz, sc-13116) was used in western blot on mouse samples (fig 6) and in western blot on brown rat samples (fig 2). Cell Death Differ (2016) ncbi
mouse monoclonal (E-1)
  • western blot; human; 1:1000; fig 5
Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz Biotechnology, sc-13116) was used in western blot on human samples at 1:1000 (fig 5). Oncotarget (2015) ncbi
mouse monoclonal (E-1)
  • immunocytochemistry; human; tbl 1
  • western blot; human; 1:1000; tbl 1
Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz, sc-13116) was used in immunocytochemistry on human samples (tbl 1) and in western blot on human samples at 1:1000 (tbl 1). Methods Mol Biol (2015) ncbi
mouse monoclonal (E-1)
  • western blot; human; fig 4
Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz, Sc-13116) was used in western blot on human samples (fig 4). Hum Exp Toxicol (2015) ncbi
mouse monoclonal (E-1)
  • western blot; brown rat
  • western blot; human
  • western blot; mouse
Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz Biotechnology, sc-13116) was used in western blot on brown rat samples , in western blot on human samples and in western blot on mouse samples . J Neurosci (2014) ncbi
mouse monoclonal (B-9)
  • immunohistochemistry - paraffin section; human; 1:200
  • western blot; human
Santa Cruz Biotechnology Aifm1 antibody (Santa Cruz Biotech, sc-55519) was used in immunohistochemistry - paraffin section on human samples at 1:200 and in western blot on human samples . PLoS ONE (2014) ncbi
Invitrogen
mouse monoclonal (4E7E11)
  • proximity ligation assay; mouse; fig 3
  • immunoprecipitation; mouse; fig 1a
  • immunocytochemistry; mouse; fig 2a
  • western blot; mouse; fig 1c
In order to discover mitochondrial connexin 43 protein-protein interactions in mouse heart, Invitrogen Aifm1 antibody (Pierce-Thermo Scientific, MA5-15880) was used in proximity ligation assay on mouse samples (fig 3), in immunoprecipitation on mouse samples (fig 1a), in immunocytochemistry on mouse samples (fig 2a) and in western blot on mouse samples (fig 1c). J Cell Mol Med (2016) ncbi
mouse monoclonal (4E7E11)
  • western blot; human; 1:4000
In order to discuss the known phenotypes related to AIFM1 mutations and further study a single patient, Invitrogen Aifm1 antibody (Pierce, MA5-15880) was used in western blot on human samples at 1:4000. Mitochondrion (2015) ncbi
R&D Systems
domestic sheep polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 1a
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1e
  • immunohistochemistry - paraffin section; rhesus macaque; 1:500; loading ...; fig 1c
In order to compared expression of apoptosis-inducing-factor in nigral dopamine neurons of mice, monkeys, and humans, R&D Systems Aifm1 antibody (R&D Systems, AF 5824) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 1a), in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1e) and in immunohistochemistry - paraffin section on rhesus macaque samples at 1:500 (fig 1c). Mov Disord (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3
R&D Systems Aifm1 antibody (R&D systems, AF1457) was used in western blot on human samples (fig 3). Onco Targets Ther (2016) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:350; loading ...; fig 7a
Abcam Aifm1 antibody (Abcam, ab1998) was used in immunohistochemistry - frozen section on mouse samples at 1:350 (fig 7a). J Comp Neurol (2019) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2
In order to discover that protein oxidative and glycoxidative damage significantly increases during human brain aging, MilliporeSigma Aifm1 antibody (Sigma, A7549) was used in western blot on human samples at 1:1000 (fig 2). Free Radic Biol Med (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D39D2)
  • immunocytochemistry; human; loading ...; fig s1
Cell Signaling Technology Aifm1 antibody (Cell Signaling Technology, 5318) was used in immunocytochemistry on human samples (fig s1). Autophagy (2019) ncbi
domestic rabbit monoclonal (D39D2)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4b
Cell Signaling Technology Aifm1 antibody (Cell Signaling, 5318) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4b). Nucleic Acids Res (2019) ncbi
domestic rabbit monoclonal (D39D2)
  • western blot; mouse; 1:1000; loading ...; fig 7e
Cell Signaling Technology Aifm1 antibody (Cell Signaling, 5318) was used in western blot on mouse samples at 1:1000 (fig 7e). Diabetologia (2019) ncbi
domestic rabbit monoclonal (D39D2)
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology Aifm1 antibody (Cell Signaling, 5318) was used in western blot on human samples (fig 1d). Mol Cell Biochem (2019) ncbi
domestic rabbit monoclonal (D39D2)
  • immunohistochemistry; human; 1:1500; loading ...; fig s2b
Cell Signaling Technology Aifm1 antibody (CST, 5318S) was used in immunohistochemistry on human samples at 1:1500 (fig s2b). Sci Adv (2018) ncbi
domestic rabbit polyclonal
  • western blot; brown rat; 1:500; fig 5
Cell Signaling Technology Aifm1 antibody (Cell Signaling, 4642) was used in western blot on brown rat samples at 1:500 (fig 5). Exp Ther Med (2016) ncbi
domestic rabbit monoclonal (D39D2)
  • western blot; mouse; 1:1000; fig 5
In order to learn about protection against acetaminophen hepatotoxicity by mitochondria-targeted antioxidant Mito-Tempo, Cell Signaling Technology Aifm1 antibody (Cell Signaling Technology, 5318) was used in western blot on mouse samples at 1:1000 (fig 5). Arch Toxicol (2017) ncbi
domestic rabbit monoclonal (D39D2)
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology Aifm1 antibody (Cell Signaling Technology, 5318) was used in western blot on mouse samples at 1:1000 (fig 3). PLoS ONE (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; fig 2e
Cell Signaling Technology Aifm1 antibody (Cell Signaling, 4642) was used in immunohistochemistry on mouse samples at 1:100 (fig 2e). Science (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 3
In order to study increased dissociation of hexokinase II from mitochondrial outer membrane by overexpression or ErbB2 rendering breast cancer cells susceptible to 3-BrPA, Cell Signaling Technology Aifm1 antibody (Cell signaling, 4642) was used in western blot on human samples at 1:1000 (fig 3). Oncol Lett (2016) ncbi
domestic rabbit monoclonal (D39D2)
  • immunocytochemistry; human; 1:400
  • western blot; human; 1:1000
Cell Signaling Technology Aifm1 antibody (Cell Signaling, D39D2) was used in immunocytochemistry on human samples at 1:400 and in western blot on human samples at 1:1000. Mol Oncol (2015) ncbi
EMD Millipore
domestic rabbit monoclonal
  • western blot; mouse
EMD Millipore Aifm1 antibody (Millipore, 04-430) was used in western blot on mouse samples . Growth Factors (2015) ncbi
Articles Reviewed
  1. Power M, Rogerson L, Schubert T, Berens P, Euler T, Paquet Durand F. Systematic spatiotemporal mapping reveals divergent cell death pathways in three mouse models of hereditary retinal degeneration. J Comp Neurol. 2019;: pubmed publisher
  2. Ding X, Jiang X, Tian R, Zhao P, Li L, Wang X, et al. RAB2 regulates the formation of autophagosome and autolysosome in mammalian cells. Autophagy. 2019;:1-13 pubmed publisher
  3. Ding D, Liu J, Dong K, Melnick A, Latham K, Chen C. Mitochondrial membrane-based initial separation of MIWI and MILI functions during pachytene piRNA biogenesis. Nucleic Acids Res. 2019;47:2594-2608 pubmed publisher
  4. Signes A, Cerutti R, Dickson A, Benincá C, Hinchy E, Ghezzi D, et al. APOPT1/COA8 assists COX assembly and is oppositely regulated by UPS and ROS. EMBO Mol Med. 2019;11: pubmed publisher
  5. Yoshitake S, Murakami T, Suzuma K, Yoshitake T, Uji A, Morooka S, et al. Anti-fumarase antibody promotes the dropout of photoreceptor inner and outer segments in diabetic macular oedema. Diabetologia. 2019;62:504-516 pubmed publisher
  6. Killackey S, Rahman M, Soares F, Zhang A, Abdel Nour M, Philpott D, et al. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Mol Cell Biochem. 2019;453:187-196 pubmed publisher
  7. NGUYEN J, Ray C, Fox A, Mendonça D, Kim J, Krebsbach P. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018;4:eaao5838 pubmed publisher
  8. Sugiura A, Mattie S, Prudent J, McBride H. Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes. Nature. 2017;542:251-254 pubmed publisher
  9. Cabre R, Naudi A, Dominguez Gonzalez M, Ayala V, Jove M, Mota Martorell N, et al. Sixty years old is the breakpoint of human frontal cortex aging. Free Radic Biol Med. 2017;103:14-22 pubmed publisher
  10. Lu H, Yang X, Tian X, Tang S, Li L, Zhao S, et al. The in vitro and vivo anti-tumor effects and molecular mechanisms of suberoylanilide hydroxamic acid (SAHA) and MG132 on the aggressive phenotypes of gastric cancer cells. Oncotarget. 2016;7:56508-56525 pubmed publisher
  11. Peneder T, Bauer J, Pifl C. Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice. Mov Disord. 2016;31:1729-1733 pubmed publisher
  12. Lin K, Cheng S, Tsai S, Tsai J, Lin C, Cheung C. Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Onco Targets Ther. 2016;9:2601-13 pubmed publisher
  13. Scott A, Wilkinson A, Wilkinson J. Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells. BMC Cancer. 2016;16:286 pubmed publisher
  14. Jeong J, Noh M, Choi J, Lee H, Kim S. Neuroprotective and antioxidant activities of bamboo salt soy sauce against H2O2-induced oxidative stress in rat cortical neurons. Exp Ther Med. 2016;11:1201-1210 pubmed
  15. Jiang L, Shestov A, Swain P, Yang C, Parker S, Wang Q, et al. Reductive carboxylation supports redox homeostasis during anchorage-independent growth. Nature. 2016;532:255-8 pubmed publisher
  16. Du K, Farhood A, Jaeschke H. Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. Arch Toxicol. 2017;91:761-773 pubmed publisher
  17. Nagase M, Kurihara H, Aiba A, Young M, Sakai T. Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice. PLoS ONE. 2016;11:e0150886 pubmed publisher
  18. Lei L, Spradling A. Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells. Science. 2016;352:95-9 pubmed publisher
  19. Denuc A, Núñez E, Calvo E, Loureiro M, Miro Casas E, Guarás A, et al. New protein-protein interactions of mitochondrial connexin 43 in mouse heart. J Cell Mol Med. 2016;20:794-803 pubmed publisher
  20. Gao S, Chen X, Jin H, Ren S, Liu Z, Fang X, et al. Overexpression of ErbB2 renders breast cancer cells susceptible to 3-BrPA through the increased dissociation of hexokinase II from mitochondrial outer membrane. Oncol Lett. 2016;11:1567-1573 pubmed
  21. Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed publisher
  22. Sabirzhanov B, Stoica B, Zhao Z, Loane D, Wu J, Dorsey S, et al. miR-711 upregulation induces neuronal cell death after traumatic brain injury. Cell Death Differ. 2016;23:654-68 pubmed publisher
  23. Loureiro R, Magalhães Novais S, Mesquita K, Baldeiras I, Sousa I, Tavares L, et al. Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells. Oncotarget. 2015;6:17081-96 pubmed
  24. Kettwig M, Schubach M, Zimmermann F, Klinge L, Mayr J, Biskup S, et al. From ventriculomegaly to severe muscular atrophy: expansion of the clinical spectrum related to mutations in AIFM1. Mitochondrion. 2015;21:12-8 pubmed publisher
  25. Liu L, Chowdhury S, Uppal S, Fang X, Liu J, Srikant C. mReg2 inhibits nuclear entry of apoptosis-inducing factor in mouse insulinoma cells. Growth Factors. 2015;33:1-7 pubmed publisher
  26. Vega Naredo I, Cunha Oliveira T, Serafim T, Sardao V, Oliveira P. Analysis of pro-apoptotic protein trafficking to and from mitochondria. Methods Mol Biol. 2015;1241:163-80 pubmed publisher
  27. Iwaniuk A, Jabłońska E, Jabłoński J, Ratajczak Wrona W, Garley M. Expression of selected proteins of the extrinsic and intrinsic pathways of apoptosis in human leukocytes exposed to N-nitrosodimethylamine. Hum Exp Toxicol. 2015;34:591-600 pubmed publisher
  28. Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, et al. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma. Mol Oncol. 2015;9:78-92 pubmed publisher
  29. Sabirzhanov B, Zhao Z, Stoica B, Loane D, Wu J, Borroto C, et al. Downregulation of miR-23a and miR-27a following experimental traumatic brain injury induces neuronal cell death through activation of proapoptotic Bcl-2 proteins. J Neurosci. 2014;34:10055-71 pubmed publisher
  30. Xu S, Wu H, Nie H, Yue L, Jiang H, Xiao S, et al. AIF downregulation and its interaction with STK3 in renal cell carcinoma. PLoS ONE. 2014;9:e100824 pubmed publisher