This is a Validated Antibody Database (VAD) review about mouse Aicda, based on 23 published articles (read how Labome selects the articles), using Aicda antibody in all methods. It is aimed to help Labome visitors find the most suited Aicda antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Aicda synonym: Aid; Arp2; single-stranded DNA cytosine deaminase; activation induced deaminase; cytidine aminohydrolase

Invitrogen
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1d
Invitrogen Aicda antibody (Invitrogen, ZA001) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1d). Histopathology (2017) ncbi
rat monoclonal (mAID-2)
  • western blot; mouse; loading ...; fig 1a
In order to report that phosphatidylinositol 3-kinase delta blockade promotes genomic instability in B cells, Invitrogen Aicda antibody (eBioScience, 14-5959-82) was used in western blot on mouse samples (fig 1a). Nature (2017) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human; 1:100; tbl 2
In order to compare leukemic non-nodal mantle cell lymphoma with classical mantle cell lymphoma and aggressive mantle cell lymphoma, Invitrogen Aicda antibody (Invitrogen, ZA001) was used in immunohistochemistry - paraffin section on human samples at 1:100 (tbl 2). Virchows Arch (2016) ncbi
rat monoclonal (mAID-2)
  • western blot; human; fig 2b
In order to demonstrate induction of functional AID by EBNA3C, Invitrogen Aicda antibody (eBioscience, mAID-2) was used in western blot on human samples (fig 2b). J Exp Med (2016) ncbi
rat monoclonal (mAID-2)
  • flow cytometry; mouse; loading ...; fig 1c
In order to identify a B cell-intrinsic mechanism by which IFN signaling promotes lupus pathogenesis, Invitrogen Aicda antibody (eBiosciences, mAID-2) was used in flow cytometry on mouse samples (fig 1c). J Exp Med (2016) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
In order to assess the use of activation-induced cytidine deaminase staining for the detection of Philadelphia chromosome-positive acute lymphoblastic leukemia, Invitrogen Aicda antibody (Invitrogen, ZA001) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Hum Pathol (2016) ncbi
mouse monoclonal (ZA001)
  • western blot; chicken; fig 1
In order to investigate the requirement for Bcl6 for somatic hypermutation and gene conversion in chicken DT40 cells, Invitrogen Aicda antibody (Invitrogen, 39-2500) was used in western blot on chicken samples (fig 1). PLoS ONE (2016) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry; human; fig 4
In order to examine AID expression, the presence of SHM mutations, CSR, and aberrant SHM in BCL6 in patients with follicular lymphoma, Invitrogen Aicda antibody (Invitrogen, ZA001) was used in immunohistochemistry on human samples (fig 4). Leuk Lymphoma (2016) ncbi
mouse monoclonal (ZA001)
  • western blot; mouse; fig 10A
In order to report a B cell-intrinsic role for Rab7, Invitrogen Aicda antibody (Cell Signaling, 39-2500) was used in western blot on mouse samples (fig 10A). J Immunol (2015) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry; human; fig 3
In order to assess the frequency and nature of BCL2 mutations in patients with follicular lymphoma, Invitrogen Aicda antibody (Life Technologies, 39-2500) was used in immunohistochemistry on human samples (fig 3). Blood (2015) ncbi
mouse monoclonal (ZA001)
  • chromatin immunoprecipitation; human
Invitrogen Aicda antibody (Invitrogen, ZA001) was used in chromatin immunoprecipitation on human samples . Leuk Lymphoma (2015) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human
Invitrogen Aicda antibody (Life Technologies, ZA001) was used in immunohistochemistry - paraffin section on human samples . Am J Transplant (2014) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human; 1:100
Invitrogen Aicda antibody (Invitrogen, 39-250) was used in immunohistochemistry - paraffin section on human samples at 1:100. Anticancer Res (2014) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human
Invitrogen Aicda antibody (Invitrogen, clone ZA001) was used in immunohistochemistry - paraffin section on human samples . PLoS ONE (2014) ncbi
rat monoclonal (mAID-2)
  • western blot; mouse; fig S2
In order to elucidate the noncanonical function of UNG, Invitrogen Aicda antibody (eBioscience, K4698) was used in western blot on mouse samples (fig S2). Proc Natl Acad Sci U S A (2014) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry; human; 1:100
Invitrogen Aicda antibody (Invitrogen, 39-250) was used in immunohistochemistry on human samples at 1:100. Anticancer Res (2014) ncbi
mouse monoclonal (ZA001)
  • immunocytochemistry; human; 1:200
  • western blot; human; 1:1000
In order to study the localization of AID and it's associated proteins, Invitrogen Aicda antibody (Invitrogen, 39-2500) was used in immunocytochemistry on human samples at 1:200 and in western blot on human samples at 1:1000. Exp Cell Res (2014) ncbi
mouse monoclonal (ZA001)
  • chromatin immunoprecipitation; human
  • immunocytochemistry; human
  • western blot; human
In order to study the role of 14-3-3 adaptor scaffold function in immunoglobulin class switch DNA recombination in B-cells, Invitrogen Aicda antibody (Invitrogen, 39-2500) was used in chromatin immunoprecipitation on human samples , in immunocytochemistry on human samples and in western blot on human samples . PLoS ONE (2013) ncbi
rat monoclonal (mAID-2)
  • immunohistochemistry - frozen section; mouse
In order to determine the mechanisms by which RGS13 promotes the generation of pathogenic autoantibodies in germinal centers, Invitrogen Aicda antibody (eBioscience, mAID-2) was used in immunohistochemistry - frozen section on mouse samples . Arthritis Rheum (2013) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human; fig 2
In order to study AID-related changes in chronic rhinosinusitis with nasal polyps, Invitrogen Aicda antibody (Invitrogen, ZA001) was used in immunohistochemistry - paraffin section on human samples (fig 2). PLoS ONE (2011) ncbi
mouse monoclonal (ZA001)
  • western blot; human; fig 1
In order to examine the expression and effect of AID on human lung cancer, Invitrogen Aicda antibody (Zymed, ZA001) was used in western blot on human samples (fig 1). Ann Surg Oncol (2011) ncbi
mouse monoclonal (ZA001)
  • immunohistochemistry - paraffin section; human; 1:40; fig 1
In order to investigate the correlation between miR-223 expression and gastric MALT lymphoma, Invitrogen Aicda antibody (Zymed Laboratories, clone ZA001) was used in immunohistochemistry - paraffin section on human samples at 1:40 (fig 1). Mod Pathol (2010) ncbi
mouse monoclonal (ZA001)
  • western blot; mouse
In order to investigate AID activity at Sgamma1, Invitrogen Aicda antibody (Zymed, 39-2500) was used in western blot on mouse samples . J Immunol (2010) ncbi
Articles Reviewed
  1. Verdanet E, Dereure O, René C, Tempier A, Benammar Hafidi A, Gallo M, et al. Diagnostic value of STMN1, LMO2, HGAL, AID expression and 1p36 chromosomal abnormalities in primary cutaneous B cell lymphomas. Histopathology. 2017;71:648-660 pubmed publisher
  2. Compagno M, Wang Q, Pighi C, Cheong T, Meng F, Poggio T, et al. Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells. Nature. 2017;542:489-493 pubmed publisher
  3. Gallo M, Cacheux V, Vincent L, Bret C, Tempier A, Guittard C, et al. Leukemic non-nodal mantle cell lymphomas have a distinct phenotype and are associated with deletion of PARP1 and 13q14. Virchows Arch. 2016;469:697-706 pubmed
  4. Kalchschmidt J, Bashford Rogers R, Paschos K, Gillman A, Styles C, Kellam P, et al. Epstein-Barr virus nuclear protein EBNA3C directly induces expression of AID and somatic mutations in B cells. J Exp Med. 2016;213:921-8 pubmed publisher
  5. Jackson S, Jacobs H, Arkatkar T, Dam E, Scharping N, Kolhatkar N, et al. B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. J Exp Med. 2016;213:733-50 pubmed publisher
  6. Shi Y, Zhao X, Durkin L, Rogers H, Hsi E. Aberrant activation-induced cytidine deaminase expression in Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia. Hum Pathol. 2016;52:173-8 pubmed publisher
  7. Williams A, Maman Y, Alinikula J, Schatz D. Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells. PLoS ONE. 2016;11:e0149146 pubmed publisher
  8. Scherer F, Navarrete M, Bertinetti Lapatki C, Boehm J, Schmitt Graeff A, Veelken H. Isotype-switched follicular lymphoma displays dissociation between activation-induced cytidine deaminase expression and somatic hypermutation. Leuk Lymphoma. 2016;57:151-60 pubmed publisher
  9. Pone E, Lam T, Lou Z, Wang R, Chen Y, Liu D, et al. B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses. J Immunol. 2015;194:3065-78 pubmed publisher
  10. Correia C, Schneider P, Dai H, Dogan A, Maurer M, Church A, et al. BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma. Blood. 2015;125:658-67 pubmed publisher
  11. Wright R, Slemmons K, Vaughan A. Estradiol induces gene proximity and MLL-MLLT3 fusion in an activation-induced cytidine deaminase-mediated pathway. Leuk Lymphoma. 2015;56:1460-5 pubmed publisher
  12. Meier D, Docena G, Ramisch D, Toscanini U, Berardi G, Gondolesi G, et al. Immunological status of isolated lymphoid follicles after intestinal transplantation. Am J Transplant. 2014;14:2148-58 pubmed publisher
  13. Batsaikhan B, Yoshikawa K, Kurita N, Iwata T, Takasu C, Kashihara H, et al. Expression of Stathmin1 in gastric adenocarcinoma. Anticancer Res. 2014;34:4217-21 pubmed
  14. Meshcheryakova A, Tamandl D, Bajna E, Stift J, Mittlboeck M, Svoboda M, et al. B cells and ectopic follicular structures: novel players in anti-tumor programming with prognostic power for patients with metastatic colorectal cancer. PLoS ONE. 2014;9:e99008 pubmed publisher
  15. Yousif A, Stanlie A, Mondal S, Honjo T, Begum N. Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase. Proc Natl Acad Sci U S A. 2014;111:E1016-24 pubmed publisher
  16. Batsaikhan B, Kurita N, Iwata T, Sato H, Yoshikawa K, Takasu C, et al. The role of activation-induced cytidine deaminase expression in gastric adenocarcinoma. Anticancer Res. 2014;34:995-1000 pubmed
  17. Hu Y, Ericsson I, Doseth B, Liabakk N, Krokan H, Kavli B. Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors. Exp Cell Res. 2014;322:178-92 pubmed publisher
  18. Lam T, Thomas L, White C, Li G, Pone E, Xu Z, et al. Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination. PLoS ONE. 2013;8:e80414 pubmed publisher
  19. Wang J, New J, Xie S, Yang P, Wu Q, Li J, et al. Extension of the germinal center stage of B cell development promotes autoantibodies in BXD2 mice. Arthritis Rheum. 2013;65:2703-12 pubmed publisher
  20. Mechtcheriakova D, Sobanov Y, Holtappels G, Bajna E, Svoboda M, Jaritz M, et al. Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component. PLoS ONE. 2011;6:e25611 pubmed publisher
  21. Shinmura K, Igarashi H, Goto M, Tao H, Yamada H, Matsuura S, et al. Aberrant expression and mutation-inducing activity of AID in human lung cancer. Ann Surg Oncol. 2011;18:2084-92 pubmed publisher
  22. Liu T, Chen S, Kuo S, Cheng A, Lin C. E2A-positive gastric MALT lymphoma has weaker plasmacytoid infiltrates and stronger expression of the memory B-cell-associated miR-223: possible correlation with stage and treatment response. Mod Pathol. 2010;23:1507-17 pubmed publisher
  23. Misaghi S, Garris C, Sun Y, Nguyen A, Zhang J, Sebrell A, et al. Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells. J Immunol. 2010;185:166-73 pubmed publisher