This is a Validated Antibody Database (VAD) review about mouse Adar, based on 16 published articles (read how Labome selects the articles), using Adar antibody in all methods. It is aimed to help Labome visitors find the most suited Adar antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Adar synonym: AV242451; Adar1; Adar1p110; Adar1p150; DRADA; mZaADAR

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (15.8.6)
  • western blot knockout validation; mouse; fig s3
Santa Cruz Biotechnology Adar antibody (Santa Cruz, sc-73408) was used in western blot knockout validation on mouse samples (fig s3). Sci Rep (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (15.8.6)
  • western blot; mouse; 1:1000; loading ...; fig 1c
Santa Cruz Biotechnology Adar antibody (Santa Cruz, sc-73408) was used in western blot on mouse samples at 1:1000 (fig 1c). J Neuroinflammation (2021) ncbi
mouse monoclonal (15.8.6)
  • western blot; human; 1:1000; loading ...; fig 1c
Santa Cruz Biotechnology Adar antibody (Santa Cruz Biotechnology, sc-73408) was used in western blot on human samples at 1:1000 (fig 1c). elife (2020) ncbi
mouse monoclonal (15.8.6)
  • western blot; mouse; loading ...; fig 6c
Santa Cruz Biotechnology Adar antibody (Santa Cruz Biotechnology, 15.8.6) was used in western blot on mouse samples (fig 6c). Nature (2019) ncbi
mouse monoclonal (15.8.6)
  • western blot; human; fig s7b
Santa Cruz Biotechnology Adar antibody (SantaCruz, sc-73408) was used in western blot on human samples (fig s7b). Cell (2018) ncbi
mouse monoclonal (15.8.6)
  • western blot; human; loading ...; fig s5a
In order to investigate the role of ILF2 in RNA splicing and DNA damage response in multiple myeloma, Santa Cruz Biotechnology Adar antibody (Santa-Cruz, sc-73408) was used in western blot on human samples (fig s5a). Cancer Cell (2017) ncbi
mouse monoclonal (15.8.6)
  • western blot; mouse; loading ...; fig 4c
Santa Cruz Biotechnology Adar antibody (Santa Cruz Biotechnology, sc-73408) was used in western blot on mouse samples (fig 4c). Nature (2017) ncbi
mouse monoclonal (15.8.6)
  • immunocytochemistry; mouse; 1:500; loading ...; fig s2
In order to elucidate how nuclear editing of substrates contributes to neuronal function and brain development, Santa Cruz Biotechnology Adar antibody (Santa Cruz, 15.8.6) was used in immunocytochemistry on mouse samples at 1:500 (fig s2). J Cell Sci (2017) ncbi
mouse monoclonal (15.8.6)
  • western blot knockout validation; mouse; fig s3
Santa Cruz Biotechnology Adar antibody (Santa Cruz, sc-73408) was used in western blot knockout validation on mouse samples (fig s3). Sci Rep (2016) ncbi
mouse monoclonal (15.8.6)
  • immunocytochemistry; human; fig 8a
Santa Cruz Biotechnology Adar antibody (Santa Cruz, sc73408) was used in immunocytochemistry on human samples (fig 8a). J Biol Chem (2016) ncbi
mouse monoclonal (15.8.6)
  • western blot; mouse; fig 2
Santa Cruz Biotechnology Adar antibody (Santa Cruz, SC73408) was used in western blot on mouse samples (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (15.8.6)
  • immunoprecipitation; human; fig s1
  • western blot; human; 1:1000; fig s11
Santa Cruz Biotechnology Adar antibody (Santa Cruz, sc-73408) was used in immunoprecipitation on human samples (fig s1) and in western blot on human samples at 1:1000 (fig s11). Nat Commun (2015) ncbi
mouse monoclonal (15.8.6)
  • western blot; mouse
In order to study the relationship between adenosine deaminase acting on RNA 1 (ADAR1) and type I IFNs, Santa Cruz Biotechnology Adar antibody (Santa Cruz, sc-73408) was used in western blot on mouse samples . J Immunol (2014) ncbi
Abcam
mouse polyclonal
  • immunohistochemistry; human; 1:1000; loading ...; fig 1b
Abcam Adar antibody (Abcam, ab88574) was used in immunohistochemistry on human samples at 1:1000 (fig 1b). Nucleic Acids Res (2018) ncbi
mouse polyclonal
  • other; human; loading ...; fig 4c
Abcam Adar antibody (Abcam, ab88574) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse polyclonal
  • other; human; fig 5c
  • immunohistochemistry; human; 1:200; fig 1e
  • western blot; human; 1:1000; fig 2b
Abcam Adar antibody (Abcam, ab88574) was used in other on human samples (fig 5c), in immunohistochemistry on human samples at 1:200 (fig 1e) and in western blot on human samples at 1:1000 (fig 2b). Sci Signal (2017) ncbi
mouse polyclonal
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Abcam Adar antibody (Abcam, ab88574) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
Articles Reviewed
  1. Guo X, Wiley C, Steinman R, Sheng Y, Ji B, Wang J, et al. Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain. J Neuroinflammation. 2021;18:169 pubmed publisher
  2. Ilik I, Malszycki M, Lübke A, Schade C, Meierhofer D, Aktas T. SON and SRRM2 are essential for nuclear speckle formation. elife. 2020;9: pubmed publisher
  3. Ishizuka J, Manguso R, Cheruiyot C, Bi K, Panda A, Iracheta Vellve A, et al. Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. Nature. 2019;565:43-48 pubmed publisher
  4. Hong H, An O, Chan T, Ng V, Kwok H, Lin J, et al. Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer. Nucleic Acids Res. 2018;46:7953-7969 pubmed publisher
  5. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  6. Ahmad S, Mu X, Yang F, Greenwald E, Park J, Jacob E, et al. Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation. Cell. 2018;172:797-810.e13 pubmed publisher
  7. Amin E, Liu Y, Deng S, Tan K, Chudgar N, Mayo M, et al. The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK. Sci Signal. 2017;10: pubmed publisher
  8. Marchesini M, Ogoti Y, Fiorini E, Aktaş Samur A, Nezi L, D Anca M, et al. ILF2 Is a Regulator of RNA Splicing and DNA Damage Response in 1q21-Amplified Multiple Myeloma. Cancer Cell. 2017;32:88-100.e6 pubmed publisher
  9. Aktas T, Avşar Ilık İ, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, et al. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature. 2017;544:115-119 pubmed publisher
  10. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  11. Behm M, Wahlstedt H, Widmark A, Eriksson M, Ohman M. Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development. J Cell Sci. 2017;130:745-753 pubmed publisher
  12. Anantharaman A, Jadaliha M, Tripathi V, Nakagawa S, Hirose T, Jantsch M, et al. Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA. Sci Rep. 2016;6:34043 pubmed publisher
  13. Nawaz M, Vik E, Berges N, Fladeby C, Bjørås M, Dalhus B, et al. Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules. J Biol Chem. 2016;291:21786-21801 pubmed
  14. Wang H, Wang G, Zhang L, Zhang J, Zhang J, Wang Q, et al. ADAR1 Suppresses the Activation of Cytosolic RNA-Sensing Signaling Pathways to Protect the Liver from Ischemia/Reperfusion Injury. Sci Rep. 2016;6:20248 pubmed publisher
  15. Bahn J, Ahn J, Lin X, Zhang Q, Lee J, Civelek M, et al. Genomic analysis of ADAR1 binding and its involvement in multiple RNA processing pathways. Nat Commun. 2015;6:6355 pubmed publisher
  16. Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, et al. Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. J Immunol. 2014;193:3436-45 pubmed publisher