This is a Validated Antibody Database (VAD) review about mouse Acan, based on 22 published articles (read how Labome selects the articles), using Acan antibody in all methods. It is aimed to help Labome visitors find the most suited Acan antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Acan synonym: Agc; Agc1; CSPCP; Cspg1; b2b183Clo; cmd

Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s2a
Abcam Acan antibody (Abcam, ab36861) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s2a). Commun Biol (2022) ncbi
mouse monoclonal (6-B-4)
  • western blot; human; 1:1000; loading ...; fig 2c
Abcam Acan antibody (Abcam, ab3778) was used in western blot on human samples at 1:1000 (fig 2c). Aging (Albany NY) (2021) ncbi
mouse monoclonal (6-B-4)
  • western blot; human; loading ...; fig 1e
Abcam Acan antibody (Abcam, ab3778) was used in western blot on human samples (fig 1e). Cell Death Dis (2021) ncbi
mouse monoclonal (6-B-4)
  • immunocytochemistry; mouse; loading ...; fig 3b
  • immunohistochemistry; rat; 1:400; loading ...; fig 2f
Abcam Acan antibody (Abcam, ab3778) was used in immunocytochemistry on mouse samples (fig 3b) and in immunohistochemistry on rat samples at 1:400 (fig 2f). Arthritis Res Ther (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3a
Abcam Acan antibody (Abcam, ab36861) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 3a). Clin Exp Dent Res (2021) ncbi
mouse monoclonal (6-B-4)
  • western blot; mouse; loading ...; fig 3a
Abcam Acan antibody (Abcam, ab3778) was used in western blot on mouse samples (fig 3a). Cell Death Dis (2021) ncbi
mouse monoclonal (6-B-4)
  • western blot; human; 1:1000; fig 7
Abcam Acan antibody (Abcam, ab3778) was used in western blot on human samples at 1:1000 (fig 7). Aging (Albany NY) (2020) ncbi
mouse monoclonal (6-B-4)
  • immunohistochemistry; human; 1:300; fig 6
Abcam Acan antibody (Abcam, ab3778) was used in immunohistochemistry on human samples at 1:300 (fig 6). BMC Biotechnol (2020) ncbi
mouse monoclonal (6-B-4)
  • western blot; mouse; 1:500; loading ...; fig 4b
Abcam Acan antibody (Abcam, ab3778) was used in western blot on mouse samples at 1:500 (fig 4b). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; loading ...; fig 1c
Abcam Acan antibody (Abcam, ab36861) was used in western blot on rat samples (fig 1c). Aging (Albany NY) (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4b
Abcam Acan antibody (Proteintech, ab36861) was used in immunohistochemistry - paraffin section on mouse samples (fig 4b). Int J Mol Sci (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2f, 3c
Abcam Acan antibody (Abcam, ab36861) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 2f, 3c). Nat Commun (2019) ncbi
mouse monoclonal (6-B-4)
  • western blot; human; 1:100; fig 5
Abcam Acan antibody (Abcam, ab3778) was used in western blot on human samples at 1:100 (fig 5). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:200; fig 7
  • western blot; rat; 1:500; fig 3
Abcam Acan antibody (Abcam, ab36861) was used in immunohistochemistry on rat samples at 1:200 (fig 7) and in western blot on rat samples at 1:500 (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (6-B-4)
  • immunocytochemistry; bovine; 1:50; loading ...; fig 2a
Abcam Acan antibody (Abcam, ab3778) was used in immunocytochemistry on bovine samples at 1:50 (fig 2a). Nat Commun (2016) ncbi
mouse monoclonal (6-B-4)
  • immunocytochemistry; human; 1:100; loading ...; fig 3c
Abcam Acan antibody (Abcam, ab3778) was used in immunocytochemistry on human samples at 1:100 (fig 3c). Int J Mol Med (2015) ncbi
mouse monoclonal (6-B-4)
  • immunohistochemistry; mouse
Abcam Acan antibody (Abcam, ab3778) was used in immunohistochemistry on mouse samples . PLoS ONE (2014) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 6a
Invitrogen Acan antibody (Thermo Scientific, PA1-1746) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 6a). Arthritis Rheumatol (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; 1 ug/ml; loading ...; fig s3b
Invitrogen Acan antibody (Thermo Fisher, PA1-1746) was used in western blot on human samples at 1 ug/ml (fig s3b). Arterioscler Thromb Vasc Biol (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 3
In order to determine the effects of hydroxytyrosol and procyanidin treatment on osteoarthritis using rabbits, Invitrogen Acan antibody (Thermo Fisher Scientific, PA1-1746) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 3). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:50; fig 2
In order to analyze development of experimental osteoarthritis and aggrecan degradation in murine articular cartilage by JNK-2, Invitrogen Acan antibody (Thermo Scientific, PA1-1746) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 2). Arthritis Rheumatol (2016) ncbi
MD Biosciences
monoclonal (BC-4)
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 4b
MD Biosciences Acan antibody (mdbiosciences, 1042002) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 4b). Cell Death Dis (2018) ncbi
Articles Reviewed
  1. Liu N, Lin Y, Li L, Lu J, Geng D, Zhang J, et al. gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes. Commun Biol. 2022;5:64 pubmed publisher
  2. Liu Y, Zhang Y. Hsa_circ_0134111 promotes osteoarthritis progression by regulating miR-224-5p/CCL1 interaction. Aging (Albany NY). 2021;13:20383-20394 pubmed publisher
  3. Coveney C, Zhu L, Miotla Zarebska J, Stott B, Parisi I, Batchelor V, et al. Role of Ciliary Protein Intraflagellar Transport Protein 88 in the Regulation of Cartilage Thickness and Osteoarthritis Development in Mice. Arthritis Rheumatol. 2022;74:49-59 pubmed publisher
  4. Hou M, Zhang Y, Zhou X, Liu T, Yang H, Chen X, et al. Kartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis. Cell Death Dis. 2021;12:483 pubmed publisher
  5. Wang W, Zhu Y, Sun Z, Jin C, Wang X. Positive feedback regulation between USP15 and ERK2 inhibits osteoarthritis progression through TGF-β/SMAD2 signaling. Arthritis Res Ther. 2021;23:84 pubmed publisher
  6. Khurel Ochir T, Izawa T, Iwasa A, Kano F, Yamamoto A, Tanaka E. The immunoregulatory role of p21 in the development of the temporomandibular joint-osteoarthritis. Clin Exp Dent Res. 2021;7:313-322 pubmed publisher
  7. Guo Q, Chen X, Chen J, Zheng G, Xie C, Wu H, et al. STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway. Cell Death Dis. 2021;12:13 pubmed publisher
  8. Wang L, Yang M, Zhang C, Huang F. The protective effects of dehydrocostus lactone against TNF-α-induced degeneration of extracellular matrix (ECM) in SW1353 cells. Aging (Albany NY). 2020;12:17137-17149 pubmed publisher
  9. Huang Y, Seitz D, Chevalier Y, Müller P, Jansson V, Klar R. Synergistic interaction of hTGF-β3 with hBMP-6 promotes articular cartilage formation in chitosan scaffolds with hADSCs: implications for regenerative medicine. BMC Biotechnol. 2020;20:48 pubmed publisher
  10. Xu Z, Ke T, Zhang Y, Fu C, He W. Agonism of GPR120 prevented IL-1β-induced reduction of extracellular matrix through SOX-9. Aging (Albany NY). 2020;12:12074-12085 pubmed publisher
  11. Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher
  12. Yang H, Zhang M, Liu Q, Zhang H, Zhang J, Lu L, et al. Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism. Int J Mol Sci. 2019;20: pubmed publisher
  13. Yin 殷晓科 X, Wanga S, Fellows A, Barallobre Barreiro J, Lu R, Davaapil H, et al. Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients. Arterioscler Thromb Vasc Biol. 2019;39:1859-1873 pubmed publisher
  14. Ji Q, Xu X, Kang L, Xu Y, Xiao J, Goodman S, et al. Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis. Nat Commun. 2019;10:313 pubmed publisher
  15. Gorth D, Shapiro I, Risbud M. Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death Dis. 2018;10:7 pubmed publisher
  16. Mével E, Merceron C, Vinatier C, Krisa S, Richard T, Masson M, et al. Olive and grape seed extract prevents post-traumatic osteoarthritis damages and exhibits in vitro anti IL-1? activities before and after oral consumption. Sci Rep. 2016;6:33527 pubmed publisher
  17. Wu X, Liu W, Duan Z, Gao Y, Li S, Wang K, et al. The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration. Sci Rep. 2016;6:30563 pubmed publisher
  18. Jiao K, Zeng G, Niu L, Yang H, Ren G, Xu X, et al. Activation of ?2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint. Sci Rep. 2016;6:30085 pubmed publisher
  19. Cote A, McLeod C, Farrell M, McClanahan P, Dunagin M, Raj A, et al. Single-cell differences in matrix gene expression do not predict matrix deposition. Nat Commun. 2016;7:10865 pubmed publisher
  20. Ismail H, Miotla Zarebska J, Troeberg L, Tang X, Stott B, Yamamoto K, et al. Brief Report: JNK-2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis. Arthritis Rheumatol. 2016;68:1165-71 pubmed publisher
  21. Ma X, Lin Y, Yang K, Yue B, Xiang H, Chen B. Effect of lentivirus-mediated survivin transfection on the morphology and apoptosis of nucleus pulposus cells derived from degenerative human disc in vitro. Int J Mol Med. 2015;36:186-94 pubmed publisher
  22. Winkler T, Mahoney E, Sinner D, Wylie C, Dahia C. Wnt signaling activates Shh signaling in early postnatal intervertebral discs, and re-activates Shh signaling in old discs in the mouse. PLoS ONE. 2014;9:e98444 pubmed publisher