This is a Validated Antibody Database (VAD) review about mouse Abcb1a, based on 31 published articles (read how Labome selects the articles), using Abcb1a antibody in all methods. It is aimed to help Labome visitors find the most suited Abcb1a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcb1a synonym: Abcb4; Evi32; Mdr1a; Mdr3; P-gp; Pgp; Pgy-3; Pgy3; mdr-3

Knockout validation
Invitrogen
mouse monoclonal (C219)
  • immunohistochemistry knockout validation; mouse; loading ...
  • western blot knockout validation; mouse; loading ...
Invitrogen Abcb1a antibody (Thermo Scientific, MA1-26528) was used in immunohistochemistry knockout validation on mouse samples and in western blot knockout validation on mouse samples . Neurotrauma Rep (2020) ncbi
Abcam
domestic rabbit monoclonal (EPR10364-57)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3c
  • western blot knockout validation; mouse; loading ...; fig 3b
Abcam Abcb1a antibody (AbCam, ab170904) was used in immunohistochemistry knockout validation on mouse samples (fig 3c) and in western blot knockout validation on mouse samples (fig 3b). Neurotrauma Rep (2020) ncbi
Invitrogen
mouse monoclonal (C219)
  • immunohistochemistry knockout validation; mouse; loading ...
  • western blot knockout validation; mouse; loading ...
Invitrogen Abcb1a antibody (Thermo Scientific, MA1-26528) was used in immunohistochemistry knockout validation on mouse samples and in western blot knockout validation on mouse samples . Neurotrauma Rep (2020) ncbi
mouse monoclonal (C219)
  • western blot; mouse; 1 ug/ml; fig 1c
Invitrogen Abcb1a antibody (ThermoFisher, MA1?C26528) was used in western blot on mouse samples at 1 ug/ml (fig 1c). Neurobiol Dis (2020) ncbi
mouse monoclonal (C219)
  • immunohistochemistry - paraffin section; human; 1:20; loading ...; fig s4
Invitrogen Abcb1a antibody (Thermo Fisher Scientific, MA1-26528) was used in immunohistochemistry - paraffin section on human samples at 1:20 (fig s4). Epilepsia (2018) ncbi
mouse monoclonal (C219)
  • immunohistochemistry; fruit fly ; fig s2d
Invitrogen Abcb1a antibody (ThermoFisher, MA1-26528) was used in immunohistochemistry on fruit fly samples (fig s2d). Cell (2018) ncbi
mouse monoclonal (C219)
  • immunohistochemistry - frozen section; rat; fig 2c
  • western blot; rat; 1:75; fig 2b
In order to develop a method to increase the intestinal transport of octreotide, Invitrogen Abcb1a antibody (Thermo Fisher, MA1-26528) was used in immunohistochemistry - frozen section on rat samples (fig 2c) and in western blot on rat samples at 1:75 (fig 2b). Exp Ther Med (2016) ncbi
mouse monoclonal (C219)
  • western blot; mouse; fig 1A
In order to generate a shortened mutant allele of P-glycoprotein to determine its structure, Invitrogen Abcb1a antibody (Invitrogen, C219) was used in western blot on mouse samples (fig 1A). J Biol Chem (2017) ncbi
mouse monoclonal (C219)
  • western blot; mouse; 1 ug/ml; loading ...; fig 2a
In order to assess the effect of caloric restriction on neurovascular functions, Invitrogen Abcb1a antibody (ThermoFisher, MA1-26528) was used in western blot on mouse samples at 1 ug/ml (fig 2a). Aging (Albany NY) (2016) ncbi
mouse monoclonal (C219)
  • western blot; pigs ; 1:1000
Invitrogen Abcb1a antibody (Zymed Laboratories, C219) was used in western blot on pigs samples at 1:1000. Biopharm Drug Dispos (2015) ncbi
mouse monoclonal (C219)
  • western blot; human; 1:20
In order to study cord blood as a source of circulating endothelial progenitor cells that can be directed towards specialized endothelial phenotypes, Invitrogen Abcb1a antibody (Thermoscientific, MA1-26528) was used in western blot on human samples at 1:20. PLoS ONE (2014) ncbi
mouse monoclonal (C219)
  • western blot; human
In order to investigate the relationship between PP5/PPP2R3C and P-gp, Invitrogen Abcb1a antibody (Invitrogen, C219) was used in western blot on human samples . Cancer Lett (2014) ncbi
Enzo Life Sciences
mouse monoclonal (C219)
  • immunocytochemistry; human; 1:100; loading ...; fig 3a
  • western blot; human; 1:300; loading ...; fig 2b
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, ALX-801-002-C100) was used in immunocytochemistry on human samples at 1:100 (fig 3a) and in western blot on human samples at 1:300 (fig 2b). Oncol Lett (2018) ncbi
mouse monoclonal (C219)
  • western blot; human; fig 7a
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, C219) was used in western blot on human samples (fig 7a). Toxicology (2016) ncbi
mouse monoclonal (C219)
  • immunocytochemistry; mouse; 1:50; fig 3c
Enzo Life Sciences Abcb1a antibody (Alexis, ALX801-002-C100) was used in immunocytochemistry on mouse samples at 1:50 (fig 3c). PLoS ONE (2016) ncbi
mouse monoclonal (C219)
  • western blot; human; loading ...; fig 5b
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, C219) was used in western blot on human samples (fig 5b). Mol Pharmacol (2016) ncbi
mouse monoclonal (C219)
  • western blot; domestic sheep; 1:100; loading ...; fig 1
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, C219) was used in western blot on domestic sheep samples at 1:100 (fig 1). J Steroid Biochem Mol Biol (2016) ncbi
mouse monoclonal (C219)
  • western blot; human; loading ...; fig 3A
Enzo Life Sciences Abcb1a antibody (ENZO, ALX-801-002-C100) was used in western blot on human samples (fig 3A). Iran J Basic Med Sci (2015) ncbi
mouse monoclonal (C219)
  • immunocytochemistry; human; 1:100
  • western blot; human
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, C219) was used in immunocytochemistry on human samples at 1:100 and in western blot on human samples . Pharm Res (2015) ncbi
mouse monoclonal (C219)
  • western blot; human; 1:250
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, ALX-801-002-C100) was used in western blot on human samples at 1:250. Anticancer Res (2014) ncbi
mouse monoclonal (C219)
  • western blot; mouse
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, C219) was used in western blot on mouse samples . Pharm Res (2013) ncbi
mouse monoclonal (C219)
  • western blot; human; 1:200
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, C-219) was used in western blot on human samples at 1:200. Antimicrob Agents Chemother (2013) ncbi
mouse monoclonal (C219)
  • immunohistochemistry - paraffin section; mouse; 1:25
Enzo Life Sciences Abcb1a antibody (Enzo Life Sciences, C219) was used in immunohistochemistry - paraffin section on mouse samples at 1:25. Int J Alzheimers Dis (2011) ncbi
Abcam
domestic rabbit monoclonal (EPR10364-57)
  • immunohistochemistry knockout validation; mouse; loading ...; fig 3c
  • western blot knockout validation; mouse; loading ...; fig 3b
Abcam Abcb1a antibody (AbCam, ab170904) was used in immunohistochemistry knockout validation on mouse samples (fig 3c) and in western blot knockout validation on mouse samples (fig 3b). Neurotrauma Rep (2020) ncbi
domestic rabbit monoclonal (EPR10364-57)
  • immunocytochemistry; mouse; 1:200; loading ...; fig 8b
  • western blot; mouse; 1:2000; loading ...; fig 8c
  • immunocytochemistry; human; 1:200; fig 8a
  • western blot; human; 1:2000; fig 8b
Abcam Abcb1a antibody (Abcam, ab170904) was used in immunocytochemistry on mouse samples at 1:200 (fig 8b), in western blot on mouse samples at 1:2000 (fig 8c), in immunocytochemistry on human samples at 1:200 (fig 8a) and in western blot on human samples at 1:2000 (fig 8b). PLoS ONE (2017) ncbi
domestic rabbit monoclonal (EPR10364-57)
  • western blot; human; 1:1000; fig s6
Abcam Abcb1a antibody (Abcam, EPR10364-57) was used in western blot on human samples at 1:1000 (fig s6). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR10364-57)
  • immunocytochemistry; human; fig 1
  • immunocytochemistry; mouse; fig s2
Abcam Abcb1a antibody (Abcam, EPR10364-57) was used in immunocytochemistry on human samples (fig 1) and in immunocytochemistry on mouse samples (fig s2). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (EPR10364-57)
  • immunohistochemistry; mouse; 1:50; fig 5
Abcam Abcb1a antibody (Abcam, ab170904) was used in immunohistochemistry on mouse samples at 1:50 (fig 5). Sci Rep (2016) ncbi
domestic rabbit monoclonal (EPR10364-57)
  • western blot; mouse; 1:500; loading ...; fig 1a,4
Abcam Abcb1a antibody (Abcam, ab170904) was used in western blot on mouse samples at 1:500 (fig 1a,4). Placenta (2015) ncbi
GeneTex
mouse monoclonal (C219)
  • immunocytochemistry; mouse; fig s2
  • western blot; mouse; 1:2000; fig s5
  • immunocytochemistry; human; fig 1
  • western blot; human; 1:2000; fig 1
GeneTex Abcb1a antibody (GeneTex, GTX23364) was used in immunocytochemistry on mouse samples (fig s2), in western blot on mouse samples at 1:2000 (fig s5), in immunocytochemistry on human samples (fig 1) and in western blot on human samples at 1:2000 (fig 1). J Clin Invest (2016) ncbi
mouse monoclonal (C219)
  • western blot; human; fig 4
GeneTex Abcb1a antibody (GeneTex, GTX23364) was used in western blot on human samples (fig 4). Theranostics (2016) ncbi
mouse monoclonal (C219)
  • western blot; human; loading ...; fig 1a
GeneTex Abcb1a antibody (Gene Tex, C219) was used in western blot on human samples (fig 1a). J Cell Mol Med (2015) ncbi
Novus Biologicals
domestic rabbit monoclonal (SN06-42)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 6d
Novus Biologicals Abcb1a antibody (Novus Biologicals, NBP2-67667) was used in immunohistochemistry - frozen section on mouse samples (fig 6d). J Clin Invest (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (3H2833)
  • western blot; human; 1:1000; loading ...; fig 4a
Santa Cruz Biotechnology Abcb1a antibody (Santa Cruz, sc-71557) was used in western blot on human samples at 1:1000 (fig 4a). Apoptosis (2017) ncbi
OriGene
mouse monoclonal (OTI2F7)
  • western blot; human
OriGene Abcb1a antibody (OriGene, TA801056) was used in western blot on human samples . Mol Cancer Ther (2015) ncbi
Articles Reviewed
  1. Vita S, Redell J, Maynard M, Zhao J, Grill R, Dash P, et al. P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury. Neurotrauma Rep. 2020;1:207-217 pubmed publisher
  2. Lin A, Parikh I, Yanckello L, White R, Hartz A, Taylor C, et al. APOE genotype-dependent pharmacogenetic responses to rapamycin for preventing Alzheimer's disease. Neurobiol Dis. 2020;139:104834 pubmed publisher
  3. Mercadante C, Prajapati M, Conboy H, Dash M, Herrera C, Pettiglio M, et al. Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity. J Clin Invest. 2019;129:5442-5461 pubmed publisher
  4. Weidner L, Kannan P, Mitsios N, Kang S, Hall M, Theodore W, et al. The expression of inflammatory markers and their potential influence on efflux transporters in drug-resistant mesial temporal lobe epilepsy tissue. Epilepsia. 2018;59:1507-1517 pubmed publisher
  5. Mieszala K, Rudewicz M, Gomulkiewicz A, Ratajczak Wielgomas K, Grzegrzolka J, Dziegiel P, et al. Expression of genes and proteins of multidrug resistance in gastric cancer cells treated with resveratrol. Oncol Lett. 2018;15:5825-5832 pubmed publisher
  6. Zhang S, Yue Z, Arnold D, Artiushin G, Sehgal A. A Circadian Clock in the Blood-Brain Barrier Regulates Xenobiotic Efflux. Cell. 2018;173:130-139.e10 pubmed publisher
  7. Lian W, Zhang L, Yang L, Chen W. AP-2α reverses vincristine-induced multidrug resistance of SGC7901 gastric cancer cells by inhibiting the Notch pathway. Apoptosis. 2017;22:933-941 pubmed publisher
  8. Sekhar G, Georgian A, Sanderson L, Vizcay Barrena G, Brown R, Muresan P, et al. Organic cation transporter 1 (OCT1) is involved in pentamidine transport at the human and mouse blood-brain barrier (BBB). PLoS ONE. 2017;12:e0173474 pubmed publisher
  9. Sun X, Duan Z, Liu Z, Tang S, Li Y, He S, et al. Inhibition of P-glycoprotein, multidrug resistance-associated protein 2 and cytochrome P450 3A4 improves the oral absorption of octreotide in rats with portal hypertension. Exp Ther Med. 2016;12:3716-3722 pubmed publisher
  10. Esser L, Zhou F, Pluchino K, Shiloach J, Ma J, Tang W, et al. Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity. J Biol Chem. 2017;292:446-461 pubmed publisher
  11. Parikh I, Guo J, Chuang K, Zhong Y, Rempe R, Hoffman J, et al. Caloric restriction preserves memory and reduces anxiety of aging mice with early enhancement of neurovascular functions. Aging (Albany NY). 2016;8:2814-2826 pubmed publisher
  12. Sayyed K, Vee M, Abdel Razzak Z, Jouan E, Stieger B, Denizot C, et al. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology. 2016;363-364:58-71 pubmed publisher
  13. Cederbye C, Palshof J, Hansen T, Duun Henriksen A, Linnemann D, Stenvang J, et al. Antibody validation and scoring guidelines for ABCG2 immunohistochemical staining in formalin-fixed paraffin-embedded colon cancer tissue. Sci Rep. 2016;6:26997 pubmed publisher
  14. Kanda M, Nagai T, Takahashi T, Liu M, Kondou N, Naito A, et al. Leukemia Inhibitory Factor Enhances Endogenous Cardiomyocyte Regeneration after Myocardial Infarction. PLoS ONE. 2016;11:e0156562 pubmed publisher
  15. Mahdi Z, Synal Hermanns U, Yoker A, Locher K, Stieger B. Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis. Mol Pharmacol. 2016;90:23-34 pubmed publisher
  16. Kim D, Bynoe M. A2A adenosine receptor modulates drug efflux transporter P-glycoprotein at the blood-brain barrier. J Clin Invest. 2016;126:1717-33 pubmed publisher
  17. Aikawa H, Hayashi M, Ryu S, Yamashita M, Ohtsuka N, Nishidate M, et al. Visualizing spatial distribution of alectinib in murine brain using quantitative mass spectrometry imaging. Sci Rep. 2016;6:23749 pubmed publisher
  18. Deng L, Li Q, Lin G, Huang D, Zeng X, Wang X, et al. P-glycoprotein Mediates Postoperative Peritoneal Adhesion Formation by Enhancing Phosphorylation of the Chloride Channel-3. Theranostics. 2016;6:204-18 pubmed publisher
  19. Wilkens M, Maté L, Schnepel N, Klinger S, Muscher Banse A, Ballent M, et al. Influence of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 on expression of P-glycoprotein and cytochrome P450 3A in sheep. J Steroid Biochem Mol Biol. 2016;164:271-276 pubmed publisher
  20. Wang C, Li H, Luo C, Li Y, Zhang Y, Yun D, et al. The effect of maternal obesity on the expression and functionality of placental P-glycoprotein: Implications in the individualized transplacental digoxin treatment for fetal heart failure. Placenta. 2015;36:1138-47 pubmed publisher
  21. Nourbakhsh M, Jaafari M, Lage H, Abnous K, Mosaffa F, Badiee A, et al. Nanolipoparticles-mediated MDR1 siRNA delivery reduces doxorubicin resistance in breast cancer cells and silences MDR1 expression in xenograft model of human breast cancer. Iran J Basic Med Sci. 2015;18:385-92 pubmed
  22. Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G. Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier. Pharm Res. 2015;32:2973-82 pubmed publisher
  23. Fantappiè O, Sassoli C, Tani A, Nosi D, Marchetti S, Formigli L, et al. Mitochondria of a human multidrug-resistant hepatocellular carcinoma cell line constitutively express inducible nitric oxide synthase in the inner membrane. J Cell Mol Med. 2015;19:1410-7 pubmed publisher
  24. Loganzo F, Tan X, Sung M, Jin G, Myers J, Melamud E, et al. Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments. Mol Cancer Ther. 2015;14:952-63 pubmed publisher
  25. Hasibu I, Patoine D, Pilote S, Drolet B, Simard C. The guinea-pig expresses functional CYP2C and P-glycoprotein: further validation of its usefulness in drug biotransformation/transport studies. Biopharm Drug Dispos. 2015;36:183-203 pubmed publisher
  26. Doherty B, Lawlor D, Gillet J, Gottesman M, O Leary J, Stordal B. Collateral sensitivity to cisplatin in KB-8-5-11 drug-resistant cancer cells. Anticancer Res. 2014;34:503-7 pubmed
  27. Boyer Di Ponio J, El Ayoubi F, Glacial F, Ganeshamoorthy K, Driancourt C, Godet M, et al. Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes. PLoS ONE. 2014;9:e84179 pubmed publisher
  28. Katayama K, Yamaguchi M, Noguchi K, Sugimoto Y. Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function. Cancer Lett. 2014;345:124-31 pubmed publisher
  29. Aleksunes L, Xu J, Lin E, Wen X, Goedken M, Slitt A. Pregnancy represses induction of efflux transporters in livers of type I diabetic mice. Pharm Res. 2013;30:2209-20 pubmed publisher
  30. Vinot C, Gavard L, Treluyer J, Manceau S, Courbon E, Scherrmann J, et al. Placental transfer of maraviroc in an ex vivo human cotyledon perfusion model and influence of ABC transporter expression. Antimicrob Agents Chemother. 2013;57:1415-20 pubmed publisher
  31. Brenn A, Grube M, Peters M, Fischer A, Jedlitschky G, Kroemer H, et al. Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice. Int J Alzheimers Dis. 2011;2011:690121 pubmed publisher