This is a Validated Antibody Database (VAD) review about mouse 3110043O21Rik, based on 4 published articles (read how Labome selects the articles), using 3110043O21Rik antibody in all methods. It is aimed to help Labome visitors find the most suited 3110043O21Rik antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
3110043O21Rik synonym: AI840585; C9orf72; guanine nucleotide exchange C9orf72 homolog; protein C9orf72 homolog

Proteintech Group
mouse monoclonal (3D2H6)
  • western blot; mouse; 1:3000; loading ...; fig 3a
In order to elucidate the mechanism by which intronic hexanucleotide expansions in C9ORF72 contribute to amyotrophic lateral sclerosis, Proteintech Group 3110043O21Rik antibody (Proteintech, 66140-1-Ig) was used in western blot on mouse samples at 1:3000 (fig 3a). Nat Neurosci (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2
Proteintech Group 3110043O21Rik antibody (Proteintech, 22637-1-AP) was used in western blot on mouse samples (fig 2). EMBO J (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:500; loading ...; fig 1c
  • western blot; mouse; 1:1000; loading ...; fig 1a
  • immunocytochemistry; human; 1:500; loading ...; fig 1c
  • western blot; human; 1:1000; loading ...; fig 1a
Proteintech Group 3110043O21Rik antibody (Proteintech, 22637-1-AP) was used in immunocytochemistry on mouse samples at 1:500 (fig 1c), in western blot on mouse samples at 1:1000 (fig 1a), in immunocytochemistry on human samples at 1:500 (fig 1c) and in western blot on human samples at 1:1000 (fig 1a). Mol Neurobiol (2017) ncbi
GeneTex
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:50
GeneTex 3110043O21Rik antibody (Genetex, GTX119776) was used in immunohistochemistry - paraffin section on human samples at 1:50. Acta Neuropathol (2011) ncbi
Articles Reviewed
  1. Sivadasan R, Hornburg D, Drepper C, Frank N, Jablonka S, Hansel A, et al. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Nat Neurosci. 2016;19:1610-1618 pubmed publisher
  2. Sellier C, Campanari M, Julie Corbier C, Gaucherot A, Kolb Cheynel I, Oulad Abdelghani M, et al. Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death. EMBO J. 2016;35:1276-97 pubmed publisher
  3. Maharjan N, Künzli C, Buthey K, Saxena S. C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress. Mol Neurobiol. 2017;54:3062-3077 pubmed publisher
  4. Al Sarraj S, King A, Troakes C, Smith B, Maekawa S, Bodi I, et al. p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD and MND/ALS. Acta Neuropathol. 2011;122:691-702 pubmed publisher