This is a Validated Antibody Database (VAD) review about human thymidine phosphorylase, based on 10 published articles (read how Labome selects the articles), using thymidine phosphorylase antibody in all methods. It is aimed to help Labome visitors find the most suited thymidine phosphorylase antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
thymidine phosphorylase synonym: ECGF; ECGF1; MEDPS1; MNGIE; MTDPS1; PDECGF; TP; hPD-ECGF

Invitrogen
mouse monoclonal (P-GF.44C)
  • immunohistochemistry - paraffin section; human; 1:500
In order to identify biomarkers relevant to treatment outcomes in gastric cancer patients receiving adjuvant S-1 chemotherapy, Invitrogen thymidine phosphorylase antibody (Thermo, P-GF. 44C) was used in immunohistochemistry - paraffin section on human samples at 1:500. PLoS ONE (2015) ncbi
mouse monoclonal (P-GF.44C)
  • immunohistochemistry - paraffin section; human; 1:100
Invitrogen thymidine phosphorylase antibody (Invitrogen, PGF-44C) was used in immunohistochemistry - paraffin section on human samples at 1:100. Anticancer Res (2014) ncbi
mouse monoclonal (P-GF.44C)
  • immunohistochemistry; human; 1:60
Invitrogen thymidine phosphorylase antibody (Thermo Fisher, PGF.44C) was used in immunohistochemistry on human samples at 1:60. Anticancer Res (2014) ncbi
mouse monoclonal (P-GF.44C)
  • ELISA; human; 0.5 ug/ml; loading ...; fig 1d
In order to discuss technical factors that influence the analysis of angiogenesis factors in the blood of tumor patients, Invitrogen thymidine phosphorylase antibody (Lab Vision, PGF.44C) was used in ELISA on human samples at 0.5 ug/ml (fig 1d). Dis Markers (2011) ncbi
mouse monoclonal (P-GF.44C)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2d
In order to assess the use of thymidylate synthase and thymidine phosphorylase as biomarkers to predict clinical outcomes of capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer, Invitrogen thymidine phosphorylase antibody (NeoMarkers, PGF.44C) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2d). Cancer Chemother Pharmacol (2011) ncbi
mouse monoclonal (P-GF.44C)
  • immunohistochemistry - paraffin section; rat; loading ...; fig 2B (c)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2A (c)
In order to evaluate the anti-tumor effect and mechanisms of cimetidine using a N-butyl-N-(4-hydroxybutyl) nitrosamine-induced model of bladder cancer, Invitrogen thymidine phosphorylase antibody (Lab Vision Corp, PGF.44C) was used in immunohistochemistry - paraffin section on rat samples (fig 2B (c)) and in immunohistochemistry - paraffin section on mouse samples (fig 2A (c)). Oncol Rep (2009) ncbi
Santa Cruz Biotechnology
mouse monoclonal (0.N.568)
  • western blot; human; fig 3
Santa Cruz Biotechnology thymidine phosphorylase antibody (Santa Cruz, sc-71867) was used in western blot on human samples (fig 3). Oncotarget (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D69B12)
  • western blot; human; 1:1000; loading ...; fig 4c
Cell Signaling Technology thymidine phosphorylase antibody (Cell Signaling, 4307) was used in western blot on human samples at 1:1000 (fig 4c). Cell Rep (2022) ncbi
domestic rabbit monoclonal (D69B12)
  • western blot; human; 1:1000; loading ...; fig 1a, s1b, s1d
  • western blot; mouse; 1:1000; loading ...; fig 1c
Cell Signaling Technology thymidine phosphorylase antibody (Cell Signaling, 4307) was used in western blot on human samples at 1:1000 (fig 1a, s1b, s1d) and in western blot on mouse samples at 1:1000 (fig 1c). Adv Sci (Weinh) (2021) ncbi
domestic rabbit monoclonal (D69B12)
  • western blot; mouse; loading ...; fig 3e
In order to explore the role of Hic-5 in breast tumor progression, Cell Signaling Technology thymidine phosphorylase antibody (Cell Signaling, 4307) was used in western blot on mouse samples (fig 3e). Oncogene (2017) ncbi
Articles Reviewed
  1. Abt E, Le T, Dann A, Capri J, Poddar S, Lok V, et al. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell Rep. 2022;38:110236 pubmed publisher
  2. Guo J, Cheng J, Zheng N, Zhang X, Dai X, Zhang L, et al. Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner. Adv Sci (Weinh). 2021;8:e2004303 pubmed publisher
  3. Goreczny G, Ouderkirk Pecone J, Olson E, Krendel M, Turner C. Hic-5 remodeling of the stromal matrix promotes breast tumor progression. Oncogene. 2017;36:2693-2703 pubmed publisher
  4. Terranova Barberio M, Roca M, Zotti A, Leone A, Bruzzese F, Vitagliano C, et al. Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression. Oncotarget. 2016;7:7715-31 pubmed publisher
  5. Kim J, Shin E, Kim J, Lee H, Lee D, Kim S, et al. Impact of intratumoral expression levels of fluoropyrimidine-metabolizing enzymes on treatment outcomes of adjuvant S-1 therapy in gastric cancer. PLoS ONE. 2015;10:e0120324 pubmed publisher
  6. Koumarianou A, Tzeveleki I, Mekras D, Eleftheraki A, Bobos M, Wirtz R, et al. Prognostic markers in early-stage colorectal cancer: significance of TYMS mRNA expression. Anticancer Res. 2014;34:4949-62 pubmed
  7. Cha Y, Han S, Seol H, Oh D, Im S, Bang Y, et al. Immunohistochemical features associated with sensitivity to lapatinib-plus-capecitabine and resistance to trastuzumab in HER2-positive breast cancer. Anticancer Res. 2014;34:4275-80 pubmed
  8. Starlinger P, Alidzanovic L, Schauer D, Brugger P, Sommerfeldt S, Kuehrer I, et al. Platelet-stored angiogenesis factors: clinical monitoring is prone to artifacts. Dis Markers. 2011;31:55-65 pubmed publisher
  9. Lee S, Choi Y, Park Y, Kim S, Cho E, Ahn J, et al. Thymidylate synthase and thymidine phosphorylase as predictive markers of capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer. Cancer Chemother Pharmacol. 2011;68:743-51 pubmed publisher
  10. Chihara Y, Fujimoto K, Miyake M, Hiasa Y, Hirao Y. Anti-tumor effect of cimetidine via inhibiting angiogenesis factors in N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse and rat bladder carcinogenesis. Oncol Rep. 2009;22:23-8 pubmed