This is a Validated Antibody Database (VAD) review about human thrombomodulin, based on 48 published articles (read how Labome selects the articles), using thrombomodulin antibody in all methods. It is aimed to help Labome visitors find the most suited thrombomodulin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
thrombomodulin synonym: AHUS6; BDCA3; CD141; THPH12; THRM; TM

BioLegend
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig 1b
BioLegend thrombomodulin antibody (BioLegend, M80) was used in flow cytometry on human samples (fig 1b). Rheumatology (Oxford) (2020) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; 3:50; loading ...; fig 1c
BioLegend thrombomodulin antibody (Biolegend, M80) was used in flow cytometry on human samples at 3:50 (fig 1c). Science (2020) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig 3c
BioLegend thrombomodulin antibody (Biolegend, 344110) was used in flow cytometry on human samples (fig 3c). Cell Rep (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig s6c
BioLegend thrombomodulin antibody (Biolegend, M80) was used in flow cytometry on human samples (fig s6c). Science (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig s2e
BioLegend thrombomodulin antibody (Biolegend, 344102) was used in flow cytometry on human samples (fig s2e). Cell (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig s1a
BioLegend thrombomodulin antibody (BioLegend, 344113) was used in flow cytometry on human samples (fig s1a). Cell (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig 6h
BioLegend thrombomodulin antibody (Biolegend, 344112) was used in flow cytometry on human samples (fig 6h). Oncoimmunology (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig s1b
BioLegend thrombomodulin antibody (BioLegend, M80) was used in flow cytometry on human samples (fig s1b). J Clin Invest (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig 4g
BioLegend thrombomodulin antibody (BioLegend, M80) was used in flow cytometry on human samples (fig 4g). Nat Med (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig 6b
BioLegend thrombomodulin antibody (BioLegend, 344110) was used in flow cytometry on human samples (fig 6b). Immunity (2019) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig 1c
BioLegend thrombomodulin antibody (BioLegend, 344104) was used in flow cytometry on human samples (fig 1c). J Exp Med (2018) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig s2d
BioLegend thrombomodulin antibody (BioLegend, 344104) was used in flow cytometry on human samples (fig s2d). Nat Immunol (2018) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig st12
In order to identify new types of human blood dendritic cells, monocytes, and progenitors through single-cell RNA-seq, BioLegend thrombomodulin antibody (Biolegend, M80) was used in flow cytometry on human samples (fig st12). Science (2017) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; loading ...; fig s3f
In order to report that autosomal recessive, partial Go-Ichi-Ni-San 1 deficiency impairs DNA replication and underlies intra-uterine and postnatal growth retardation, chronic neutropenia, and natural killer cell deficiency, BioLegend thrombomodulin antibody (BioLegend, M80) was used in flow cytometry on human samples (fig s3f). J Clin Invest (2017) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; fig s3
In order to determine the differential regulation of the inflammatory phenotype of brain microvascular endothelial cells by pro-inflammatory TNFalpha and IL-1beta, BioLegend thrombomodulin antibody (Biolegend, 344106) was used in flow cytometry on human samples (fig s3). J Neuroinflammation (2015) ncbi
mouse monoclonal (M80)
  • flow cytometry; human; fig 5
In order to study human cord blood and bone marrow for restricted dendritic cell and monocyte progenitors, BioLegend thrombomodulin antibody (BioLegend, M80) was used in flow cytometry on human samples (fig 5). J Exp Med (2015) ncbi
mouse monoclonal (M80)
  • flow cytometry; human
BioLegend thrombomodulin antibody (Biolegend, M80) was used in flow cytometry on human samples . Hepatology (2015) ncbi
mouse monoclonal (M80)
  • flow cytometry; human
BioLegend thrombomodulin antibody (BioLegend, M80) was used in flow cytometry on human samples . J Immunol (2014) ncbi
Miltenyi Biotec
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig 4b
Miltenyi Biotec thrombomodulin antibody (Miltenyi, AD5-14H12) was used in flow cytometry on human samples (fig 4b). J Virol (2019) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig 1c
In order to evaluate the role of IL-32alpha in NK cell inhibition, Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotec, AD14H12) was used in flow cytometry on human samples (fig 1c). J Immunol (2017) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig s4c
In order to map the lineage of human dendritic cells, Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotec, AD5-14H12) was used in flow cytometry on human samples (fig s4c). Science (2017) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig st12
In order to identify new types of human blood dendritic cells, monocytes, and progenitors through single-cell RNA-seq, Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotec, AD5-14H12) was used in flow cytometry on human samples (fig st12). Science (2017) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig 3b
In order to compare methods of isolating skin mononuclear phagocytes, Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotech, AD4-14H12) was used in flow cytometry on human samples (fig 3b). J Leukoc Biol (2017) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig 3b
In order to use CRISPR/Cas9 editing to generate reagents to study the role of IRF8 in human hematopoiesis, Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotech, AD5-14H12) was used in flow cytometry on human samples (fig 3b). Stem Cells (2017) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig 1b
In order to determine which cells express CD83, Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotec, AD5-14H12) was used in flow cytometry on human samples (fig 1b). J Immunol (2016) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...
In order to assess the role of C1q in downregulating allergic inflammation, Miltenyi Biotec thrombomodulin antibody (Miltenyi, AD5-14H12) was used in flow cytometry on human samples . Mucosal Immunol (2017) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...
Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotec, AD5-14H12) was used in flow cytometry on human samples . J Allergy Clin Immunol (2016) ncbi
mouse monoclonal (AD5-14H12)
  • flow cytometry; human; loading ...; fig 3b
Miltenyi Biotec thrombomodulin antibody (Miltenyi Biotec, AD5-14H12) was used in flow cytometry on human samples (fig 3b). J Immunol (2016) ncbi
Abcam
domestic rabbit monoclonal (EPR4051)
  • immunohistochemistry; rat; 1:200; loading ...; fig 7a
Abcam thrombomodulin antibody (Abcam, ab109189) was used in immunohistochemistry on rat samples at 1:200 (fig 7a). Front Cardiovasc Med (2022) ncbi
mouse monoclonal (PBS-01)
  • immunohistochemistry - frozen section; pigs ; 1:2000; fig 1
  • flow cytometry; pigs ; fig 1
In order to analyze how chimeric 2C10R4 anti-CD40 antibody therapy is essential for long-term survival of pig-to-primate cardiac xenograft (GTKO.hCD46.hTBM), Abcam thrombomodulin antibody (Abcam, PBS-0) was used in immunohistochemistry - frozen section on pigs samples at 1:2000 (fig 1) and in flow cytometry on pigs samples (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (PBS-01)
  • western blot; human; 1 ug/ml; fig 1a
Abcam thrombomodulin antibody (Abcam, ab6980) was used in western blot on human samples at 1 ug/ml (fig 1a). Microvasc Res (2015) ncbi
domestic rabbit monoclonal (EPR4051)
  • immunocytochemistry; human; tbl 1
In order to study the effect of innate lymphoid cells on B cells, Abcam thrombomodulin antibody (Epitomics, 2927-1) was used in immunocytochemistry on human samples (tbl 1). Nat Immunol (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-3)
  • western blot; human; loading ...; fig 7a, 7b
Santa Cruz Biotechnology thrombomodulin antibody (Santa Cruz, sc-13164) was used in western blot on human samples (fig 7a, 7b). PLoS Pathog (2022) ncbi
mouse monoclonal (D-3)
  • blocking or activating experiments; human; loading ...; fig 1c
  • immunocytochemistry; human; loading ...; fig 6c
  • western blot; human; loading ...; fig 6b
Santa Cruz Biotechnology thrombomodulin antibody (Santa Cruz Biotechnology, sc-13164) was used in blocking or activating experiments on human samples (fig 1c), in immunocytochemistry on human samples (fig 6c) and in western blot on human samples (fig 6b). Oncotarget (2016) ncbi
mouse monoclonal (D-3)
  • immunohistochemistry; rat; 1:100
Santa Cruz Biotechnology thrombomodulin antibody (Santa Cruz Biotechnology, sc-13164) was used in immunohistochemistry on rat samples at 1:100. Cell Tissue Res (2014) ncbi
Invitrogen
mouse monoclonal (141C01 (1009))
  • immunohistochemistry; human; loading ...; fig 7i
Invitrogen thrombomodulin antibody (Thermo Fisher, 141C01) was used in immunohistochemistry on human samples (fig 7i). J Clin Invest (2019) ncbi
mouse monoclonal (141C01 (1009))
  • immunohistochemistry; human; 1:25; fig 2
In order to study low grade urothelial carcinoma mimicking transitional metaplasia and basal cell hyperplasia in needle prostate biopsy, Invitrogen thrombomodulin antibody (Thermo Scientific, 141C01) was used in immunohistochemistry on human samples at 1:25 (fig 2). Int Braz J Urol (2016) ncbi
Novus Biologicals
mouse monoclonal (6C8.2F9)
  • western blot; human; fig 4b
Novus Biologicals thrombomodulin antibody (NOVUS, NBP2-42213) was used in western blot on human samples (fig 4b). Biomed Pharmacother (2019) ncbi
Dako
mouse monoclonal (1009)
  • immunohistochemistry - paraffin section; human; loading ...; fig s1a
Dako thrombomodulin antibody (DAKO, M0617) was used in immunohistochemistry - paraffin section on human samples (fig s1a). PLoS Pathog (2022) ncbi
mouse monoclonal (1009)
  • immunohistochemistry - paraffin section; human; 1:100; fig 9
Dako thrombomodulin antibody (DAKO, M0617) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 9). PLoS ONE (2016) ncbi
BD Biosciences
mouse monoclonal (1A4)
  • flow cytometry; human; 1:300; loading ...; fig 6a
BD Biosciences thrombomodulin antibody (BD Biosciences, 1A4) was used in flow cytometry on human samples at 1:300 (fig 6a). Nat Commun (2021) ncbi
mouse monoclonal (1A4)
  • flow cytometry; human; loading ...; fig 7b
BD Biosciences thrombomodulin antibody (BD, 1A4) was used in flow cytometry on human samples (fig 7b). J Exp Med (2020) ncbi
rat monoclonal (LS17-9)
  • flow cytometry; mouse; loading ...; fig s7d
BD Biosciences thrombomodulin antibody (BD Bioscience, 566338) was used in flow cytometry on mouse samples (fig s7d). Bone Res (2019) ncbi
mouse monoclonal (1A4)
  • flow cytometry; rhesus macaque; loading ...; fig 2d
BD Biosciences thrombomodulin antibody (BD Biosciences, 1A4) was used in flow cytometry on rhesus macaque samples (fig 2d). J Virol (2019) ncbi
mouse monoclonal (1A4)
  • flow cytometry; human; loading ...; fig s1
BD Biosciences thrombomodulin antibody (BD Bioscience, 1A4) was used in flow cytometry on human samples (fig s1). J Biol Chem (2018) ncbi
mouse monoclonal (1A4)
  • other; human; fig s1
In order to investigate the mechanisms of toxicity by the negative allosteric modulators of metabotropic glutamate receptor 5, BD Biosciences thrombomodulin antibody (BD/Pharm, 559780) was used in other on human samples (fig s1). Cell Chem Biol (2017) ncbi
mouse monoclonal (1A4)
  • mass cytometry; human; loading ...; fig 1j
In order to map the lineage of human dendritic cells, BD Biosciences thrombomodulin antibody (BD Biosciences, 1A4) was used in mass cytometry on human samples (fig 1j). Science (2017) ncbi
mouse monoclonal (1A4)
  • flow cytometry; human; loading ...; fig 3b
In order to compare methods of isolating skin mononuclear phagocytes, BD Biosciences thrombomodulin antibody (Becton Dickinson, 1A4) was used in flow cytometry on human samples (fig 3b). J Leukoc Biol (2017) ncbi
mouse monoclonal (1A4)
  • flow cytometry; human; loading ...
In order to identify RLTPR in patients and determine the effects of these mutations on CD4 positive T cells, BD Biosciences thrombomodulin antibody (BD, 1A4) was used in flow cytometry on human samples . J Exp Med (2016) ncbi
mouse monoclonal (1A4)
  • flow cytometry; human; loading ...; fig s1e
In order to compare expression and function of the CD300 family of receptors between neonatal and adult immune cells, BD Biosciences thrombomodulin antibody (BD Biosciences, 1A4) was used in flow cytometry on human samples (fig s1e). Sci Rep (2016) ncbi
mouse monoclonal (1A4)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, BD Biosciences thrombomodulin antibody (BD, 559781) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
mouse monoclonal (1A4)
  • flow cytometry; human
BD Biosciences thrombomodulin antibody (Becton Dickinson, 1A4) was used in flow cytometry on human samples . J Leukoc Biol (2015) ncbi
Articles Reviewed
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  2. Hsieh L, Dos Santos S, Hall B, Ogbechi J, Loglo A, Salguero F, et al. Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions. PLoS Pathog. 2022;18:e1010280 pubmed publisher
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  12. Jordan S, Tung N, Casanova Acebes M, Chang C, Cantoni C, Zhang D, et al. Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool. Cell. 2019;178:1102-1114.e17 pubmed publisher
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  27. Cottineau J, Kottemann M, Lach F, Kang Y, Vély F, Deenick E, et al. Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency. J Clin Invest. 2017;127:1991-2006 pubmed publisher
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  29. Sontag S, Förster M, Qin J, Wanek P, Mitzka S, Schüler H, et al. Modelling IRF8 Deficient Human Hematopoiesis and Dendritic Cell Development with Engineered iPS Cells. Stem Cells. 2017;35:898-908 pubmed publisher
  30. Ju X, Silveira P, Hsu W, Elgundi Z, Alingcastre R, Verma N, et al. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population. J Immunol. 2016;197:4613-4625 pubmed
  31. Mascarell L, Airouche S, Berjont N, Gary C, Gueguen C, Fourcade G, et al. The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammation. Mucosal Immunol. 2017;10:695-704 pubmed publisher
  32. Wang Y, Ma C, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, et al. Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016;213:2413-2435 pubmed
  33. Hsu Y, Shi G, Wang K, Ma C, Cheng T, Wu H. Thrombomodulin promotes focal adhesion kinase activation and contributes to angiogenesis by binding to fibronectin. Oncotarget. 2016;7:68122-68139 pubmed publisher
  34. Zenarruzabeitia O, Vitallé J, Garcia Obregon S, Astigarraga I, Eguizabal C, Santos S, et al. The expression and function of human CD300 receptors on blood circulating mononuclear cells are distinct in neonates and adults. Sci Rep. 2016;6:32693 pubmed publisher
  35. Cerny D, Thi Le D, The T, Zuest R, Kg S, Velumani S, et al. Complete human CD1a deficiency on Langerhans cells due to a rare point mutation in the coding sequence. J Allergy Clin Immunol. 2016;138:1709-1712.e11 pubmed publisher
  36. Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al. Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016;197:885-98 pubmed publisher
  37. Arista Nasr J, Martinez Benitez B, Bornstein Quevedo L, Aguilar Ayala E, Aleman Sanchez C, Ortiz Bautista R. Low grade urothelial carcinoma mimicking basal cell hyperplasia and transitional metaplasia in needle prostate biopsy. Int Braz J Urol. 2016;42:247-52 pubmed publisher
  38. Mohiuddin M, Singh A, Corcoran P, Thomas Iii M, Clark T, Lewis B, et al. Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft. Nat Commun. 2016;7:11138 pubmed publisher
  39. Leone D, Kozakowski N, Kornauth C, Waidacher T, Neudert B, Loeffler A, et al. The Phenotypic Characterization of the Human Renal Mononuclear Phagocytes Reveal a Co-Ordinated Response to Injury. PLoS ONE. 2016;11:e0151674 pubmed publisher
  40. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  41. O Carroll S, Kho D, Wiltshire R, Nelson V, Rotimi O, Johnson R, et al. Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells. J Neuroinflammation. 2015;12:131 pubmed publisher
  42. Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed publisher
  43. Bigley V, McGovern N, Milne P, Dickinson R, Pagan S, Cookson S, et al. Langerin-expressing dendritic cells in human tissues are related to CD1c+ dendritic cells and distinct from Langerhans cells and CD141high XCR1+ dendritic cells. J Leukoc Biol. 2015;97:627-34 pubmed publisher
  44. Velazquez V, Uebelhoer L, Thapa M, Ibegbu C, Courtney C, Bosinger S, et al. Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development. Hepatology. 2015;61:843-56 pubmed publisher
  45. Maney N, Reynolds G, Krippner Heidenreich A, Hilkens C. Dendritic cell maturation and survival are differentially regulated by TNFR1 and TNFR2. J Immunol. 2014;193:4914-4923 pubmed publisher
  46. Rochfort K, Cummins P. Thrombomodulin regulation in human brain microvascular endothelial cells in vitro: role of cytokines and shear stress. Microvasc Res. 2015;97:1-5 pubmed publisher
  47. Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol. 2014;15:354-364 pubmed publisher
  48. Uehara K, Uehara A. Integrin ?v?5 in endothelial cells of rat splenic sinus: an immunohistochemical and ultrastructural study. Cell Tissue Res. 2014;356:183-93 pubmed publisher