This is a Validated Antibody Database (VAD) review about human thioredoxin, based on 13 published articles (read how Labome selects the articles), using thioredoxin antibody in all methods. It is aimed to help Labome visitors find the most suited thioredoxin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
thioredoxin synonym: TRDX; TRX; TRX1

Abcam
domestic rabbit polyclonal
  • immunohistochemistry; rat; loading ...; fig 3c
Abcam thioredoxin antibody (Abcam, ab86255) was used in immunohistochemistry on rat samples (fig 3c). Cells (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
  • western blot; rat; 1:1000; loading ...; fig 4a
Abcam thioredoxin antibody (Abcam, ab26320) was used in western blot on human samples at 1:1000 (fig 5a) and in western blot on rat samples at 1:1000 (fig 4a). Biosci Rep (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig s1c
Abcam thioredoxin antibody (Abcam, ab86255) was used in western blot on human samples at 1:2000 (fig s1c). Atherosclerosis (2019) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig s9
  • western blot; human; 1:1000; loading ...; fig s9
Abcam thioredoxin antibody (Abcam, ab86255) was used in western blot on rat samples at 1:1000 (fig s9) and in western blot on human samples at 1:1000 (fig s9). Nat Commun (2016) ncbi
domestic rabbit monoclonal (EPR6110)
  • immunohistochemistry - paraffin section; human; 1:5000; fig 1
  • western blot; human; 1:5000; fig 2
Abcam thioredoxin antibody (abcam, ab133524) was used in immunohistochemistry - paraffin section on human samples at 1:5000 (fig 1) and in western blot on human samples at 1:5000 (fig 2). Lab Invest (2016) ncbi
MABTECH
mouse monoclonal (MT13X3)
  • ELISA; human; fig 9
MABTECH thioredoxin antibody (Mabtech, 3580-6) was used in ELISA on human samples (fig 9). PLoS ONE (2016) ncbi
mouse monoclonal (MT17R6)
  • ELISA; human; fig 9
  • western blot; human; fig 9
MABTECH thioredoxin antibody (Mabtech, 3580-3) was used in ELISA on human samples (fig 9) and in western blot on human samples (fig 9). PLoS ONE (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (3A1)
  • western blot; human; 1:200; loading ...; fig 1a
In order to demonstrate the pathophysiological relevance of thioredoxin-1 in celiac disease, Santa Cruz Biotechnology thioredoxin antibody (Santa Cruz, 58440) was used in western blot on human samples at 1:200 (fig 1a). J Biol Chem (2017) ncbi
mouse monoclonal (3A1)
  • immunohistochemistry - paraffin section; human
  • western blot; human
In order to investigate the role of thioredoxin-1/peroxiredoxin-1 in atherosclerosis, Santa Cruz Biotechnology thioredoxin antibody (Santa Cruz Biotechnology, sc-58440) was used in immunohistochemistry - paraffin section on human samples and in western blot on human samples . Free Radic Biol Med (2015) ncbi
Invitrogen
domestic rabbit monoclonal (H.753.8)
  • western blot; human; 1:2000; loading ...; fig 2d
In order to demonstrate the pathophysiological relevance of thioredoxin-1 in celiac disease, Invitrogen thioredoxin antibody (Thermo, H.753.8) was used in western blot on human samples at 1:2000 (fig 2d). J Biol Chem (2017) ncbi
Abnova
mouse monoclonal (2A7)
  • immunocytochemistry; human; 1:250; fig 2
Abnova thioredoxin antibody (Abnova, H00007295-M01) was used in immunocytochemistry on human samples at 1:250 (fig 2). Lab Invest (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C63C6)
  • western blot; human; 1:1000; loading ...; fig 3h
Cell Signaling Technology thioredoxin antibody (Cell Signaling, 2429) was used in western blot on human samples at 1:1000 (fig 3h). elife (2019) ncbi
domestic rabbit monoclonal (C63C6)
  • western blot; human; loading ...; fig s4j
Cell Signaling Technology thioredoxin antibody (Cell Signaling Technology, 2429) was used in western blot on human samples (fig s4j). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 5a
  • western blot; mouse; fig 5b
Cell Signaling Technology thioredoxin antibody (Cell Signalling, 2285S) was used in western blot on human samples (fig 5a) and in western blot on mouse samples (fig 5b). Oncogene (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
In order to characterize the P2X7R-secretome in M1 and M2 macrophages., Cell Signaling Technology thioredoxin antibody (Cell Signalling, 2298) was used in western blot on mouse samples (fig 2a). Sci Rep (2016) ncbi
domestic rabbit monoclonal (C63C6)
  • western blot; human; fig s5
In order to investigate role of PRDXs in lymphoma, Cell Signaling Technology thioredoxin antibody (Cell Signalling, 2429) was used in western blot on human samples (fig s5). Oncotarget (2016) ncbi
Articles Reviewed
  1. Blois S, Prince P, Borowski S, Galleano M, Barrientos G. Placental Glycoredox Dysregulation Associated with Disease Progression in an Animal Model of Superimposed Preeclampsia. Cells. 2021;10: pubmed publisher
  2. Fei J, Sun Y, Duan Y, Xia J, Yu S, Ouyang P, et al. Low concentration of rutin treatment might alleviate the cardiotoxicity effect of pirarubicin on cardiomyocytes via activation of PI3K/AKT/mTOR signaling pathway. Biosci Rep. 2019;: pubmed publisher
  3. Kang Y, Torrente L, Falzone A, Elkins C, Liu M, Asara J, et al. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. elife. 2019;8: pubmed publisher
  4. Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed publisher
  5. Zhu Y, Zhang Y, Huang X, Xie Y, Qu Y, Long H, et al. Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes. Atherosclerosis. 2019;284:110-120 pubmed publisher
  6. Plugis N, Palanski B, Weng C, Albertelli M, Khosla C. Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: IMPLICATIONS FOR CELIAC DISEASE. J Biol Chem. 2017;292:2000-2008 pubmed publisher
  7. Dunnill C, Ibraheem K, Mohamed A, Southgate J, Georgopoulos N. A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis. Oncogene. 2017;36:2515-2528 pubmed publisher
  8. de Torre Minguela C, Barberà Cremades M, Gómez A, Martín Sánchez F, Pelegrín P. Macrophage activation and polarization modify P2X7 receptor secretome influencing the inflammatory process. Sci Rep. 2016;6:22586 pubmed publisher
  9. Reiser K, Mathys L, Curbo S, Pannecouque C, Noppen S, Liekens S, et al. The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition. PLoS ONE. 2016;11:e0147773 pubmed publisher
  10. Binolfi A, Limatola A, Verzini S, Kosten J, Theillet F, Rose H, et al. Intracellular repair of oxidation-damaged α-synuclein fails to target C-terminal modification sites. Nat Commun. 2016;7:10251 pubmed publisher
  11. Ahrens T, Timme S, Ostendorp J, Bogatyreva L, Hoeppner J, Hopt U, et al. Response of esophageal cancer cells to epigenetic inhibitors is mediated via altered thioredoxin activity. Lab Invest. 2016;96:307-16 pubmed publisher
  12. Trzeciecka A, Klossowski S, Bajor M, Zagozdzon R, Gaj P, Muchowicz A, et al. Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma. Oncotarget. 2016;7:1717-31 pubmed publisher
  13. Madrigal Matute J, Fernandez García C, Blanco Colio L, Burillo E, Fortuño A, Martinez Pinna R, et al. Thioredoxin-1/peroxiredoxin-1 as sensors of oxidative stress mediated by NADPH oxidase activity in atherosclerosis. Free Radic Biol Med. 2015;86:352-61 pubmed publisher