This is a Validated Antibody Database (VAD) review about human raptor, based on 89 published articles (read how Labome selects the articles), using raptor antibody in all methods. It is aimed to help Labome visitors find the most suited raptor antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
raptor synonym: KOG1; Mip1

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (24C12)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1s1a
Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s1a). elife (2020) ncbi
Santa Cruz Biotechnology
mouse monoclonal (10E10)
  • western blot; human; loading ...; fig 2a
Santa Cruz Biotechnology raptor antibody (SantaCruz, sc81537) was used in western blot on human samples (fig 2a). Breast Cancer Res Treat (2018) ncbi
mouse monoclonal (10E10)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 4
Santa Cruz Biotechnology raptor antibody (Santa Cruz, sc81537) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 4). Oncogene (2016) ncbi
mouse monoclonal (10E10)
  • western blot; human; fig 5
Santa Cruz Biotechnology raptor antibody (Santa Cruz, sc-81537) was used in western blot on human samples (fig 5). Mol Cancer Res (2015) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5a
Invitrogen raptor antibody (ThermoFisher, 42-4000) was used in western blot on mouse samples at 1:1000 (fig 5a). Nature (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s3d
Invitrogen raptor antibody (Thermo Fisher, 42-4000) was used in western blot on human samples (fig s3d). Proc Natl Acad Sci U S A (2018) ncbi
domestic rabbit polyclonal
  • proximity ligation assay; human; loading ...; fig s7
  • western blot; human; loading ...; fig s4b
In order to examine the role of mammalian target of rapamycin in adipocytes, Invitrogen raptor antibody (ThermoFisher Scientific, PA5-20126) was used in proximity ligation assay on human samples (fig s7) and in western blot on human samples (fig s4b). Proc Natl Acad Sci U S A (2016) ncbi
Abcam
domestic rabbit monoclonal (EP539Y)
  • immunocytochemistry; human; 1:100
Abcam raptor antibody (Abcam, ab40768) was used in immunocytochemistry on human samples at 1:100. Pathol Oncol Res (2014) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig s2d
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig s2d). EMBO J (2022) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...
Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot on human samples at 1:1000. Aging (Albany NY) (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on human samples (fig 6c). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6c
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2083) was used in western blot on human samples (fig 6c). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 7g
Cell Signaling Technology raptor antibody (Cell signaling technology, 2280) was used in western blot on human samples (fig 7g). Nat Commun (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; fig 2b
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples at 1:1000 (fig 2b). Sci Rep (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; rat; loading ...; fig 3c
Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot on rat samples (fig 3c). Cell Rep (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 3c, 3e
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 3c, 3e). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:500; loading ...; fig s1d
  • western blot; human; 1:500; loading ...; fig s1d
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples at 1:500 (fig s1d) and in western blot on human samples at 1:500 (fig s1d). Mol Cancer (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; loading ...; fig 5c , 7i
  • western blot; human; 1:1000; loading ...; fig 7e, 7g
Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot on mouse samples at 1:1000 (fig 5c , 7i) and in western blot on human samples at 1:1000 (fig 7e, 7g). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2083) was used in western blot on human samples (fig 2b). Sci Adv (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on human samples (fig 2b). Sci Adv (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:200; loading ...; fig s8g
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples at 1:200 (fig s8g). Nat Commun (2021) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 2b
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 2b). BMC Cancer (2020) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on human samples (fig 2c). Cell (2020) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...; fig s3h
Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot on human samples at 1:1000 (fig s3h). J Exp Med (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig s3h
Cell Signaling Technology raptor antibody (CST, 2083) was used in western blot on human samples at 1:1000 (fig s3h). J Exp Med (2020) ncbi
domestic rabbit monoclonal (24C12)
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 1s1a
Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1s1a). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 7a
Cell Signaling Technology raptor antibody (CST, 2083) was used in western blot on rat samples at 1:1000 (fig 7a). Theranostics (2020) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:750; loading ...; fig 7g
Cell Signaling Technology raptor antibody (CST, 24C12) was used in western blot on mouse samples at 1:750 (fig 7g). Nat Commun (2020) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot on human samples (fig 6a). Cell Death Dis (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology raptor antibody (CST, 2083) was used in western blot on human samples (fig 6a). Cell Death Dis (2020) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 6a
Cell Signaling Technology raptor antibody (Cell Signaling Technologies, 2280) was used in western blot on mouse samples (fig 6a). Life Sci (2019) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on human samples at 1:1000 (fig 1s1b). elife (2019) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 1f
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 1f). Cell Rep (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1b
Cell Signaling Technology raptor antibody (Cell Signaling, 2083) was used in western blot on mouse samples (fig 1b). Cell Signal (2019) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 4c
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig 4c). Cell Signal (2019) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; loading ...; fig s3b
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples at 1:1000 (fig s3b). Nat Commun (2018) ncbi
domestic rabbit monoclonal (24C12)
  • immunoprecipitation; mouse; 1:100; loading ...; fig 9j
  • western blot; mouse; 1:1000; loading ...; fig 9j
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in immunoprecipitation on mouse samples at 1:100 (fig 9j) and in western blot on mouse samples at 1:1000 (fig 9j). Nature (2018) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...; fig 3b
Cell Signaling Technology raptor antibody (CST, 2280S) was used in western blot on human samples at 1:1000 (fig 3b). Sci Adv (2018) ncbi
domestic rabbit monoclonal (24C12)
  • other; human; loading ...; fig 4c
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 2f
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig 2f). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...; fig 3c
In order to research the effect of methyl-beta-cyclodextrin on autophagy flux in Niemann-Pick C1-deficient cells, Cell Signaling Technology raptor antibody (Cell Signaling, 2280s) was used in western blot on human samples at 1:1000 (fig 3c). Autophagy (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 1d
Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on human samples (fig 1d). Nature (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig s12d
In order to study the effects of interleukin-10 on macrophages and inflammation, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig s12d). Science (2017) ncbi
domestic rabbit monoclonal (24C12)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Cell Signaling Technology raptor antibody (CST, 2280) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 2c
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2083) was used in western blot on human samples (fig 2c). Nature (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; fig s7d
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig s7d). Nature (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on mouse samples (fig 7a). J Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 7a
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2083) was used in western blot on mouse samples (fig 7a). J Cell Biol (2017) ncbi
domestic rabbit monoclonal (24C12)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...; fig 3f
In order to elucidate that mTORC1 presents tumor suppressor features in conditions of nutrient restrictions, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples at 1:1000 (fig 3f). Nat Commun (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig 1f
In order to research the role of polo like kinase 1 in MTOR complex 1 and autophagy, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 1f). Autophagy (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; loading ...; fig 9e
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples at 1:1000 (fig 9e). J Neurosci (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 6b
In order to confirm that FBXL5 contributes to regulation of neural stem-progenitor cells proliferation during mammalian brain development, Cell Signaling Technology raptor antibody (CST, 2280) was used in western blot on mouse samples (fig 6b). Mol Cell Biol (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 9a
Cell Signaling Technology raptor antibody (Cell Signaling Technologies, 2280) was used in western blot on mouse samples (fig 9a). Mol Cell Biol (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...
In order to analyze the context specificity of signaling networks within a causal conceptual framework using reverse-phase protein array time-course assays and network analysis approaches, Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on human samples . Cell Syst (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 2e
  • western blot; rat; loading ...; fig 2f
Cell Signaling Technology raptor antibody (Cell Signalling, 2280) was used in western blot on mouse samples (fig 2e) and in western blot on rat samples (fig 2f). Hum Mol Genet (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 6a
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 6a). Cell (2016) ncbi
domestic rabbit monoclonal (24C12)
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 1a
In order to discuss mutations that contribute to atopic dermatitis, Cell Signaling Technology raptor antibody (Cell signaling, 24C12) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1a). J Allergy Clin Immunol (2017) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...; fig 4-s2a
In order to discover that mTOR is a calmodulin-dependent kinase, Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on human samples at 1:1000 (fig 4-s2a). elife (2016) ncbi
domestic rabbit polyclonal
  • flow cytometry; mouse; loading ...; fig 6a
In order to investigate the role of mTOR in plasma cell differentiation and antibody production in RAPTOR deficient cells., Cell Signaling Technology raptor antibody (Cell Signaling, 2083) was used in flow cytometry on mouse samples (fig 6a). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; loading ...; fig 3c
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on human samples at 1:1000 (fig 3c). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig s7
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology raptor antibody (Cell signaling, 2083) was used in western blot on human samples at 1:1000 (fig s7). Nat Commun (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; fig 3
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology raptor antibody (Cell signaling, 24C12) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 3b, 4a, 5b, 6a, 7a
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig 3b, 4a, 5b, 6a, 7a). Am J Physiol Endocrinol Metab (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3b, 4a, 5b, 6a, 7a
Cell Signaling Technology raptor antibody (Cell Signaling, 2083) was used in western blot on mouse samples (fig 3b, 4a, 5b, 6a, 7a). Am J Physiol Endocrinol Metab (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...
In order to show that pituitary tumor transforming gene 1 expression is upregulated in an mammalian/mechanistic target of rapamycin complex 1-dependent manner, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples . Oncogene (2017) ncbi
domestic rabbit monoclonal (24C12)
  • immunoprecipitation; human; 1:1000; fig s2
  • western blot; human; 1:1000; fig 3
Cell Signaling Technology raptor antibody (Cell Signaling Technologies, 2280) was used in immunoprecipitation on human samples at 1:1000 (fig s2) and in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; fig 7
In order to describe a signaling pathway from beta-adrenergic receptor and protein kinase A via mTORC1 that is required for adipose browning by catecholamines, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig 7). J Clin Invest (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; dogs; 1:1000; fig 3A
In order to assess induction of renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway due to ZO-2 silencing, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on dogs samples at 1:1000 (fig 3A). Mol Biol Cell (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology raptor antibody (Cell Signaling, 2083S) was used in western blot on human samples at 1:1000 (fig 2). Nat Cell Biol (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; 1:1000; fig 2
Cell Signaling Technology raptor antibody (Cell Signaling, 2280S) was used in western blot on human samples at 1:1000 (fig 2). Nat Cell Biol (2016) ncbi
domestic rabbit monoclonal (24C12)
  • immunoprecipitation; human; fig s5
  • western blot; human; fig s5
In order to study the requisite for the function of regulatory T cells known as phosphatase PP2A, Cell Signaling Technology raptor antibody (Cell Signaling, 24C12) was used in immunoprecipitation on human samples (fig s5) and in western blot on human samples (fig s5). Nat Immunol (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology raptor antibody (Cell Signaling Technologies, 2083) was used in western blot on mouse samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; fig 6
Cell Signaling Technology raptor antibody (Cell Signaling Technologies, 2280) was used in western blot on mouse samples at 1:1000 (fig 6). Nat Commun (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig s4e
Cell Signaling Technology raptor antibody (Cell Signaling Technologies, 2280) was used in western blot on human samples (fig s4e). Science (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; loading ...; fig 3d, 3f,
  • western blot; human; loading ...; fig 1c, s3d
In order to study the function of AMP-activated protein kinase in stress-induced mitochondrial fission, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig 3d, 3f,) and in western blot on human samples (fig 1c, s3d). Science (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1c, s3d
  • western blot; mouse; loading ...; fig 3d, 3f,
In order to study the function of AMP-activated protein kinase in stress-induced mitochondrial fission, Cell Signaling Technology raptor antibody (Cell Signaling, 2083) was used in western blot on human samples (fig 1c, s3d) and in western blot on mouse samples (fig 3d, 3f,). Science (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; loading ...; fig 5c
Cell Signaling Technology raptor antibody (Cell Signaling, cs-2280) was used in western blot on mouse samples at 1:1000 (fig 5c). EMBO Mol Med (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5c
Cell Signaling Technology raptor antibody (Cell Signaling, cs-2083) was used in western blot on mouse samples at 1:1000 (fig 5c). EMBO Mol Med (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; fig 1
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 4
Cell Signaling Technology raptor antibody (Cell signaling, 2083) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 4
Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; fig 1a
In order to determine how reuglations of m TORC1 signalling occurs by SUMOylation of AMPK alpha 1 through PIAS4, Cell Signaling Technology raptor antibody (Cell Signaling technology, 2280) was used in western blot on mouse samples at 1:1000 (fig 1a). Nat Commun (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 5
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 5). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 5
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
domestic rabbit monoclonal (24C12)
  • immunocytochemistry; mouse; fig s6
Cell Signaling Technology raptor antibody (Cell Signaling, 24C12) was used in immunocytochemistry on mouse samples (fig s6). elife (2015) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2083S) was used in western blot on human samples (fig 3). Mol Cancer Res (2016) ncbi
domestic rabbit monoclonal (24C12)
  • immunoprecipitation; human; fig 3
  • western blot; human; fig 3
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280S) was used in immunoprecipitation on human samples (fig 3) and in western blot on human samples (fig 3). Mol Cancer Res (2016) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 4
Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on human samples (fig 4). Cell Rep (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 3
Cell Signaling Technology raptor antibody (Cell Signaling, 2280S) was used in western blot on human samples (fig 3). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (24C12)
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; mouse; loading ...; fig 1d
Cell Signaling Technology raptor antibody (Cell Signaling, 24C12) was used in immunohistochemistry on human samples (fig 2c) and in western blot on mouse samples (fig 1d). EMBO Rep (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; rat; fig 10
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on rat samples (fig 10). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; fig 5
In order to demonstrate that mTORC1 activation downregulates the CDK8-CycC complex and elevates lipogenic protein expression, Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig 5). PLoS ONE (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; loading ...; fig s4b
Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on human samples (fig s4b). Cell Rep (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on mouse samples . Cell Signal (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse
  • western blot; human
In order to show that FKBP12 and FKBP51 levels determine the responsiveness of a cell line or tissue to rapamycin, Cell Signaling Technology raptor antibody (Cell Signaling, #2280) was used in western blot on mouse samples and in western blot on human samples . Aging Cell (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 9
  • western blot; mouse; fig 2
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 9) and in western blot on mouse samples (fig 2). Mol Cell Biol (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; 1:1000; fig s3c
Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on mouse samples at 1:1000 (fig s3c). Science (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 3
Cell Signaling Technology raptor antibody (Cell signaling, 2280) was used in western blot on human samples (fig 3). Nature (2015) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 1
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on human samples (fig 1). Oncotarget (2014) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human
In order to investigate the nucleolar targeting of isopeptidase SENP3, Cell Signaling Technology raptor antibody (Cell Signaling, 2280S) was used in western blot on human samples . Mol Cell Biol (2014) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; human; fig 2
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on human samples (fig 2). Biochem Biophys Res Commun (2014) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse; fig 3
Cell Signaling Technology raptor antibody (Cell Signaling, 2280) was used in western blot on mouse samples (fig 3). Autophagy (2014) ncbi
domestic rabbit monoclonal (24C12)
  • western blot; mouse
Cell Signaling Technology raptor antibody (Cell Signaling Technology, 2280) was used in western blot on mouse samples . Cell Signal (2014) ncbi
Articles Reviewed
  1. Sun J, Liu Y, Hao X, Lin W, Su W, Chiang E, et al. LAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function. EMBO J. 2022;41:e108119 pubmed publisher
  2. Liao M, Hu F, Qiu Z, Li J, Huang C, Xu Y, et al. Pim-2 kinase inhibits inflammation by suppressing the mTORC1 pathway in atherosclerosis. Aging (Albany NY). 2021;13:22412-22431 pubmed publisher
  3. Zhang S, Liang S, Wu D, Guo H, Ma K, Liu L. LncRNA coordinates Hippo and mTORC1 pathway activation in cancer. Cell Death Dis. 2021;12:822 pubmed publisher
  4. Yuan T, Annamalai K, Naik S, Lupse B, Geravandi S, Pal A, et al. The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis. Nat Commun. 2021;12:4928 pubmed publisher
  5. Vinsland E, Baskaran P, Mihaylov S, Hobbs C, Wood H, Bouybayoune I, et al. The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021;11:16299 pubmed publisher
  6. Lupse B, Annamalai K, Ibrahim H, Kaur S, Geravandi S, Sarma B, et al. Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes. Cell Rep. 2021;36:109490 pubmed publisher
  7. Chen X, Miao M, Zhou M, Chen J, Li D, Zhang L, et al. Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway. Cell Death Dis. 2021;12:761 pubmed publisher
  8. Yan C, Saleh N, Yang J, Nebhan C, Vilgelm A, Reddy E, et al. Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade. Mol Cancer. 2021;20:85 pubmed publisher
  9. Ma N, Wang Y, Xu S, Ni Q, Zheng Q, Zhu B, et al. PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling. Nat Commun. 2021;12:3059 pubmed publisher
  10. Hung C, Lombardo P, Malik N, Brun S, Hellberg K, Van Nostrand J, et al. AMPK/ULK1-mediated phosphorylation of Parkin ACT domain mediates an early step in mitophagy. Sci Adv. 2021;7: pubmed publisher
  11. Ramirez Martinez A, Zhang Y, Chen K, Kim J, Cenik B, McAnally J, et al. The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization. Nat Commun. 2021;12:690 pubmed publisher
  12. Saurabh K, Shah P, Doll M, Siskind L, Beverly L. UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target. BMC Cancer. 2020;20:824 pubmed publisher
  13. Koundouros N, Karali E, Tripp A, Valle A, Inglese P, Perry N, et al. Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids. Cell. 2020;181:1596-1611.e27 pubmed publisher
  14. Hermanova I, Z iga Garc a P, Caro Maldonado A, Fernandez Ruiz S, Salvador F, Mart n Mart n N, et al. Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer. J Exp Med. 2020;217: pubmed publisher
  15. McCabe M, Cullen E, Barrows C, Shore A, Tooke K, Laprade K, et al. Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission. elife. 2020;9: pubmed publisher
  16. Li R, Li D, Wu C, Ye L, Wu Y, Yuan Y, et al. Nerve growth factor activates autophagy in Schwann cells to enhance myelin debris clearance and to expedite nerve regeneration. Theranostics. 2020;10:1649-1677 pubmed publisher
  17. Viscarra J, Wang Y, Nguyen H, Choi Y, Sul H. Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis. Nat Commun. 2020;11:796 pubmed publisher
  18. Liu X, Ma F, Liu C, Zhu K, Li W, Xu Y, et al. UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop. Cell Death Dis. 2020;11:10 pubmed publisher
  19. Gao H, Freeling J, Wu P, Liang A, Wang X, Li Y. UCHL1 regulates muscle fibers and mTORC1 activity in skeletal muscle. Life Sci. 2019;233:116699 pubmed publisher
  20. Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher
  21. Losier T, Akuma M, McKee Muir O, LeBlond N, Suk Y, Alsaadi R, et al. AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles. Cell Rep. 2019;26:2150-2165.e5 pubmed publisher
  22. Ducommun S, Deak M, Zeigerer A, Göransson O, Seitz S, Collodet C, et al. Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates. Cell Signal. 2019;57:45-57 pubmed publisher
  23. Poulopoulos A, Murphy A, Ozkan A, Davis P, Hatch J, Kirchner R, et al. Subcellular transcriptomes and proteomes of developing axon projections in the cerebral cortex. Nature. 2019;565:356-360 pubmed publisher
  24. Wang F, Meng M, Mo B, Yang Y, Ji Y, Huang P, et al. Crosstalks between mTORC1 and mTORC2 variagate cytokine signaling to control NK maturation and effector function. Nat Commun. 2018;9:4874 pubmed publisher
  25. Shi G, OZOG S, Torbett B, Compton A. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proc Natl Acad Sci U S A. 2018;115:E10069-E10078 pubmed publisher
  26. Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed publisher
  27. NGUYEN J, Ray C, Fox A, Mendonça D, Kim J, Krebsbach P. Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration. Sci Adv. 2018;4:eaao5838 pubmed publisher
  28. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  29. Bostner J, Alayev A, Berman A, Fornander T, Nordenskjold B, Holz M, et al. Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer. Breast Cancer Res Treat. 2018;168:17-27 pubmed publisher
  30. Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed publisher
  31. Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher
  32. Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, et al. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling. Nature. 2017;545:365-369 pubmed publisher
  33. Ip W, Hoshi N, Shouval D, Snapper S, Medzhitov R. Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages. Science. 2017;356:513-519 pubmed publisher
  34. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  35. Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed publisher
  36. Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher
  37. Qiao A, Jin X, Pang J, Moskophidis D, Mivechi N. The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. J Cell Biol. 2017;216:723-741 pubmed publisher
  38. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  39. Villar V, Nguyen T, Delcroix V, Terés S, Bouchecareilh M, Salin B, et al. mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitation. Nat Commun. 2017;8:14124 pubmed publisher
  40. Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed publisher
  41. Hussain R, Macklin W. Integrin-Linked Kinase (ILK) Deletion Disrupts Oligodendrocyte Development by Altering Cell Cycle. J Neurosci. 2017;37:397-412 pubmed publisher
  42. Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama K. FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017;37: pubmed publisher
  43. Fitter S, Matthews M, Martin S, Xie J, Ooi S, Walkley C, et al. mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation. Mol Cell Biol. 2017;37: pubmed publisher
  44. Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed publisher
  45. Jin F, Jiang K, Ji S, Wang L, Ni Z, Huang F, et al. Deficient TSC1/TSC2-complex suppression of SOX9-osteopontin-AKT signalling cascade constrains tumour growth in tuberous sclerosis complex. Hum Mol Genet. 2017;26:407-419 pubmed publisher
  46. Wu L, Zhou B, Oshiro Rapley N, Li M, Paulo J, Webster C, et al. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016;167:1705-1718.e13 pubmed publisher
  47. Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
  48. Li R, Xu J, Fu C, Zhang J, Zheng Y, Jia H, et al. Regulation of mTORC1 by lysosomal calcium and calmodulin. elife. 2016;5: pubmed publisher
  49. Jones D, Gaudette B, Wilmore J, Chernova I, Bortnick A, Weiss B, et al. mTOR has distinct functions in generating versus sustaining humoral immunity. J Clin Invest. 2016;126:4250-4261 pubmed publisher
  50. Chen Y, Xu J, Skanderup A, Dong Y, Brannon A, Wang L, et al. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nat Commun. 2016;7:13131 pubmed publisher
  51. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  52. Bultot L, Jensen T, Lai Y, Madsen A, Collodet C, Kviklyte S, et al. Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle. Am J Physiol Endocrinol Metab. 2016;311:E706-E719 pubmed publisher
  53. Chen R, Duan J, Li L, Ma Q, Sun Q, Ma J, et al. mTOR promotes pituitary tumor development through activation of PTTG1. Oncogene. 2017;36:979-988 pubmed publisher
  54. Wu X, Schneider N, Platen A, Mitra I, Blazek M, Zengerle R, et al. In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip. Proc Natl Acad Sci U S A. 2016;113:E4143-50 pubmed publisher
  55. Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
  56. Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for ?-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  57. Domínguez Calderón A, Ávila Flores A, Ponce A, López Bayghen E, Calderón Salinas J, Luis Reyes J, et al. ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway. Mol Biol Cell. 2016;27:1581-95 pubmed publisher
  58. Liu X, Xiao Z, Han L, Zhang J, Lee S, Wang W, et al. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nat Cell Biol. 2016;18:431-42 pubmed publisher
  59. Apostolidis S, Rodríguez Rodríguez N, Suárez Fueyo A, Dioufa N, Ozcan E, Crispín J, et al. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016;17:556-64 pubmed publisher
  60. Johanns M, Lai Y, Hsu M, Jacobs R, Vertommen D, Van Sande J, et al. AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B. Nat Commun. 2016;7:10856 pubmed publisher
  61. Ben Sahra I, Hoxhaj G, Ricoult S, Asara J, Manning B. mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle. Science. 2016;351:728-733 pubmed publisher
  62. Toyama E, Herzig S, Courchet J, Lewis T, Losón O, Hellberg K, et al. Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress. Science. 2016;351:275-281 pubmed publisher
  63. Albert V, Svensson K, Shimobayashi M, Colombi M, Munoz S, Jimenez V, et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med. 2016;8:232-46 pubmed publisher
  64. Kim K, Qiang L, Hayden M, Sparling D, Purcell N, Pajvani U. mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2. Nat Commun. 2016;7:10255 pubmed publisher
  65. Zhao F, Huang W, Zhang Z, Mao L, Han Y, Yan J, et al. Triptolide induces protective autophagy through activation of the CaMKKβ-AMPK signaling pathway in prostate cancer cells. Oncotarget. 2016;7:5366-82 pubmed publisher
  66. Yan Y, Ollila S, Wong I, Vallenius T, Palvimo J, Vaahtomeri K, et al. SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling. Nat Commun. 2015;6:8979 pubmed publisher
  67. Yasuda K, Takahashi M, Mori N. Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression. PLoS ONE. 2015;10:e0142943 pubmed publisher
  68. Ye Z, Al Aidaroos A, Park J, Yuen H, Zhang S, Gupta A, et al. PRL-3 activates mTORC1 in Cancer Progression. Sci Rep. 2015;5:17046 pubmed publisher
  69. Alayev A, Salamon R, Berger S, Schwartz N, Cuesta R, Snyder R, et al. mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation. Oncogene. 2016;35:3535-43 pubmed publisher
  70. Ramiscal R, Parish I, Lee Young R, Babon J, Blagih J, Pratama A, et al. Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation. elife. 2015;4: pubmed publisher
  71. Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed publisher
  72. Ritho J, Arold S, Yeh E. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress. Cell Rep. 2015;12:734-42 pubmed publisher
  73. Jiang S, Zou Z, Nie P, Wen R, Xiao Y, Tang J. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells. PLoS ONE. 2015;10:e0132880 pubmed publisher
  74. Zidek L, Ackermann T, Hartleben G, Eichwald S, Kortman G, Kiehntopf M, et al. Deficiency in mTORC1-controlled C/EBPβ-mRNA translation improves metabolic health in mice. EMBO Rep. 2015;16:1022-36 pubmed publisher
  75. Nishida H, Ikegami A, Kaneko C, Kakuma H, Nishi H, Tanaka N, et al. Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats. PLoS ONE. 2015;10:e0128805 pubmed publisher
  76. Feng D, Youn D, Zhao X, Gao Y, Quinn W, Xiaoli A, et al. mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). PLoS ONE. 2015;10:e0126240 pubmed publisher
  77. Sujobert P, Poulain L, Paubelle E, Zylbersztejn F, Grenier A, Lambert M, et al. Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia. Cell Rep. 2015;11:1446-57 pubmed publisher
  78. Ducommun S, Deak M, Sumpton D, Ford R, Núñez Galindo A, Kussmann M, et al. Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate. Cell Signal. 2015;27:978-88 pubmed publisher
  79. Schreiber K, Ortiz D, Academia E, Anies A, Liao C, Kennedy B. Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins. Aging Cell. 2015;14:265-73 pubmed publisher
  80. Wang S, Amato K, Song W, Youngblood V, Lee K, Boothby M, et al. Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways. Mol Cell Biol. 2015;35:1299-313 pubmed publisher
  81. Jewell J, Kim Y, Russell R, Yu F, Park H, Plouffe S, et al. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science. 2015;347:194-8 pubmed publisher
  82. Rebsamen M, Pochini L, Stasyk T, de Araújo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed publisher
  83. Kocher B, White L, Piwnica Worms D. DAPK3 suppresses acini morphogenesis and is required for mouse development. Mol Cancer Res. 2015;13:358-67 pubmed publisher
  84. Kazyken D, Kaz Y, Kiyan V, Zhylkibayev A, Chen C, Agarwal N, et al. The nuclear import of ribosomal proteins is regulated by mTOR. Oncotarget. 2014;5:9577-93 pubmed
  85. Raman N, Nayak A, Muller S. mTOR signaling regulates nucleolar targeting of the SUMO-specific isopeptidase SENP3. Mol Cell Biol. 2014;34:4474-84 pubmed publisher
  86. Dufour M, Faes S, Dormond Meuwly A, Demartines N, Dormond O. PGE2-induced colon cancer growth is mediated by mTORC1. Biochem Biophys Res Commun. 2014;451:587-91 pubmed publisher
  87. Pócza T, Sebestyen A, Turányi E, Krenacs T, Márk A, Sticz T, et al. mTOR pathway as a potential target in a subset of human medulloblastoma. Pathol Oncol Res. 2014;20:893-900 pubmed publisher
  88. Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed publisher
  89. Frey J, Jacobs B, Goodman C, Hornberger T. A role for Raptor phosphorylation in the mechanical activation of mTOR signaling. Cell Signal. 2014;26:313-22 pubmed publisher