This is a Validated Antibody Database (VAD) review about human pyruvate carboxylase, based on 7 published articles (read how Labome selects the articles), using pyruvate carboxylase antibody in all methods. It is aimed to help Labome visitors find the most suited pyruvate carboxylase antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
pyruvate carboxylase synonym: PCB

Santa Cruz Biotechnology
mouse monoclonal (H-2)
  • western blot; rat; fig s1t
Santa Cruz Biotechnology pyruvate carboxylase antibody (SantaCruz, sc-271493) was used in western blot on rat samples (fig s1t). Cell (2018) ncbi
mouse monoclonal (H-2)
  • western blot; mouse; loading ...; fig 5
Santa Cruz Biotechnology pyruvate carboxylase antibody (SantaCruz, sc-271493) was used in western blot on mouse samples (fig 5). J Physiol Sci (2018) ncbi
mouse monoclonal (H-2)
  • western blot; human; loading ...; fig 4a
Santa Cruz Biotechnology pyruvate carboxylase antibody (Santa Cruz, sc-271493) was used in western blot on human samples (fig 4a). Oncotarget (2016) ncbi
mouse monoclonal (H-2)
  • western blot; rat; fig e3
Santa Cruz Biotechnology pyruvate carboxylase antibody (Santa Cruz Biotechnology, sc-271493) was used in western blot on rat samples (fig e3). Nature (2014) ncbi
Abcam
domestic rabbit monoclonal (EPR7366)
  • western blot; human; loading ...; fig 5a
Abcam pyruvate carboxylase antibody (Abcam, ab126707) was used in western blot on human samples (fig 5a). Oncotarget (2017) ncbi
domestic rabbit monoclonal (EPR7366)
  • western blot; human; 1:10,000; fig 4
Abcam pyruvate carboxylase antibody (Abcam, ab126707) was used in western blot on human samples at 1:10,000 (fig 4). Nat Cell Biol (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s6c
Novus Biologicals pyruvate carboxylase antibody (Novus, NBP1-4953655) was used in western blot on mouse samples (fig s6c). Science (2019) ncbi
Articles Reviewed
  1. Leone R, Zhao L, Englert J, Sun I, Oh M, Sun I, et al. Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion. Science. 2019;366:1013-1021 pubmed publisher
  2. Perry R, Wang Y, Cline G, Rabin Court A, Song J, Dufour S, et al. Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation. Cell. 2018;172:234-248.e17 pubmed publisher
  3. Muñoz V, Gaspar R, Crisol B, Formigari G, Sant Ana M, Botezelli J, et al. Physical exercise reduces pyruvate carboxylase (PCB) and contributes to hyperglycemia reduction in obese mice. J Physiol Sci. 2018;68:493-501 pubmed publisher
  4. Kitazawa S, Ebara S, Ando A, Baba Y, Satomi Y, Soga T, et al. Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors. Oncotarget. 2017;8:28922-28938 pubmed publisher
  5. Yin C, He D, Chen S, Tan X, Sang N. Exogenous pyruvate facilitates cancer cell adaptation to hypoxia by serving as an oxygen surrogate. Oncotarget. 2016;7:47494-47510 pubmed publisher
  6. Cardaci S, Zheng L, Mackay G, van den Broek N, MacKenzie E, Nixon C, et al. Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis. Nat Cell Biol. 2015;17:1317-26 pubmed publisher
  7. Madiraju A, Erion D, Rahimi Y, Zhang X, Braddock D, Albright R, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 2014;510:542-6 pubmed publisher