This is a Validated Antibody Database (VAD) review about human plakophilin 2, based on 6 published articles (read how Labome selects the articles), using plakophilin 2 antibody in all methods. It is aimed to help Labome visitors find the most suited plakophilin 2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
plakophilin 2 synonym: ARVD9

Santa Cruz Biotechnology
mouse monoclonal
  • western blot; human; 1:200; loading ...; fig 1b
Santa Cruz Biotechnology plakophilin 2 antibody (Santa Cruz, sc-393711) was used in western blot on human samples at 1:200 (fig 1b). Sci Rep (2021) ncbi
mouse monoclonal (28)
  • western blot; human; loading ...; fig 2b, 3b
Santa Cruz Biotechnology plakophilin 2 antibody (Santa Cruz, sc-136039) was used in western blot on human samples (fig 2b, 3b). Int J Cancer (2018) ncbi
Progen
mouse monoclonal (PP2/62; PP2/86; PP2/150)
  • immunocytochemistry; mouse; 1:10; loading ...; fig 1g
Progen plakophilin 2 antibody (Progen, 651101) was used in immunocytochemistry on mouse samples at 1:10 (fig 1g). J Cell Sci (2019) ncbi
mouse monoclonal (PP2/62; PP2/86; PP2/150)
  • immunocytochemistry; mouse; 1:300; fig 3a
In order to discuss the cellular origins of fibroadipocytes in arrhythmogenic cardiomyopathy, Progen plakophilin 2 antibody (Progen, 651101) was used in immunocytochemistry on mouse samples at 1:300 (fig 3a). Circ Res (2016) ncbi
mouse monoclonal (PP2/62; PP2/86; PP2/150)
  • immunocytochemistry; rat; loading ...; fig 1a
  • western blot; rat; loading ...; fig 8b
  • western blot; mouse; loading ...; fig 3c
Progen plakophilin 2 antibody (Progen, 651101) was used in immunocytochemistry on rat samples (fig 1a), in western blot on rat samples (fig 8b) and in western blot on mouse samples (fig 3c). J Cell Biol (2016) ncbi
Meridian Life Science
mouse monoclonal (Mixed)
  • immunohistochemistry - frozen section; domestic sheep
In order to study the role of desmosomes and adherens junctions in gap junction formation by cx43, Meridian Life Science plakophilin 2 antibody (Biodesign, K44262M) was used in immunohistochemistry - frozen section on domestic sheep samples . Heart Rhythm (2012) ncbi
Articles Reviewed
  1. Shelton W, Thomas S, Alexander H, Thomes C, Conway D, Dubash A. Desmoglein-2 harnesses a PDZ-GEF2/Rap1 signaling axis to control cell spreading and focal adhesions independent of cell-cell adhesion. Sci Rep. 2021;11:13295 pubmed publisher
  2. Li Y, Merkel C, Zeng X, Heier J, Cantrell P, Sun M, et al. The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics. J Cell Sci. 2019;132: pubmed publisher
  3. Niell N, Larriba M, Ferrer Mayorga G, Sanchez Perez I, Cantero R, Real F, et al. The human PKP2/plakophilin-2 gene is induced by Wnt/?-catenin in normal and colon cancer-associated fibroblasts. Int J Cancer. 2018;142:792-804 pubmed publisher
  4. Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
  5. Dubash A, Kam C, Aguado B, Patel D, Delmar M, Shea L, et al. Plakophilin-2 loss promotes TGF-β1/p38 MAPK-dependent fibrotic gene expression in cardiomyocytes. J Cell Biol. 2016;212:425-38 pubmed publisher
  6. Chkourko H, Guerrero Serna G, Lin X, Darwish N, Pohlmann J, Cook K, et al. Remodeling of mechanical junctions and of microtubule-associated proteins accompany cardiac connexin43 lateralization. Heart Rhythm. 2012;9:1133-1140.e6 pubmed publisher