This is a Validated Antibody Database (VAD) review about human perforin, based on 55 published articles (read how Labome selects the articles), using perforin antibody in all methods. It is aimed to help Labome visitors find the most suited perforin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
perforin synonym: HPLH2; PFP; perforin-1; cytolysin; lymphocyte pore-forming protein; perforin 1 (pore forming protein)

BioLegend
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; fig s1d
BioLegend perforin antibody (Biolegend, B-D48) was used in flow cytometry on human samples (fig s1d). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human; loading ...; fig 1j
BioLegend perforin antibody (BioLegend, dG9) was used in flow cytometry on human samples (fig 1j). PLoS Pathog (2018) ncbi
mouse monoclonal (dG9)
  • other; human; loading ...; fig 1b
BioLegend perforin antibody (BioLegend, dG9) was used in other on human samples (fig 1b). J Cell Biol (2018) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; fig 2a
BioLegend perforin antibody (BioLegend, B-D48) was used in flow cytometry on human samples (fig 2a). Sci Immunol (2018) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; fig 4f
BioLegend perforin antibody (BioLegend, B-D48) was used in flow cytometry on human samples (fig 4f). Nature (2017) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; fig 6b
In order to detail MAIT cell responses to various microorganisms and cytokines, BioLegend perforin antibody (BioLegend, B-D48) was used in flow cytometry on human samples (fig 6b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human; loading ...; fig 3a
In order to use CD49a expression to define subsets of tissue-resident memory T cells in the skin, BioLegend perforin antibody (Biolegend, dG9) was used in flow cytometry on human samples (fig 3a). Immunity (2017) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; tbl s9
In order to optimize and assess potential malaria vaccine regimens, BioLegend perforin antibody (BioLegend, 353303) was used in flow cytometry on human samples (tbl s9). Nature (2017) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...
In order to show T cell immunoglobulin and ITIM domain expression increases over time despite early initiation of antiretroviral treatment, BioLegend perforin antibody (Biolegend, B-D48) was used in flow cytometry on human samples . Sci Rep (2017) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human; fig 1e
In order to investigate the role of Eomes in the retention of liver natural killer cells, BioLegend perforin antibody (BioLegend, dG9) was used in flow cytometry on human samples (fig 1e). J Immunol (2016) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; fig 2f
In order to study the cytolytic effector capacity of HIV-specific CD8+ T cells, BioLegend perforin antibody (Biolegend, B-D48) was used in flow cytometry on human samples (fig 2f). PLoS Pathog (2016) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; fig 6a
BioLegend perforin antibody (Biolegend, B-D48) was used in flow cytometry on human samples (fig 6a). J Immunol (2016) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human; 5 ug/ml; fig 5
BioLegend perforin antibody (BioLegend, dG9) was used in flow cytometry on human samples at 5 ug/ml (fig 5). Nat Commun (2016) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human; loading ...; fig s1
In order to characterize innate lymphoid cell subpopulations isolated from patients with systemic sclerosis, BioLegend perforin antibody (biolegend, dG9) was used in flow cytometry on human samples (fig s1). J Immunol (2016) ncbi
mouse monoclonal (dG9)
  • immunocytochemistry; human; fig 8
In order to study how DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production, BioLegend perforin antibody (BioLegend, dG9) was used in immunocytochemistry on human samples (fig 8). J Exp Med (2015) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human
BioLegend perforin antibody (BioLegend, dG9) was used in flow cytometry on human samples . Clin Cancer Res (2016) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; fig 1
In order to assess arming of MAIT cell cytolytic antimicrobial activity and induction by IL-7 and faulty in HIV-1 infection, BioLegend perforin antibody (Biolegend, B-D48) was used in flow cytometry on human samples (fig 1). PLoS Pathog (2015) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human; 2.5 mg/ml; fig 3
BioLegend perforin antibody (BioLegend, dG9) was used in flow cytometry on human samples at 2.5 mg/ml (fig 3). J Surg Res (2015) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human; fig 4
BioLegend perforin antibody (Biolegend, dG9) was used in flow cytometry on human samples (fig 4). Eur J Immunol (2015) ncbi
mouse monoclonal (dG9)
  • immunocytochemistry; human
In order to examine human differentiated effector CD4(+) T cells that are defined by low levels of IL-2 and IL-7 receptors, BioLegend perforin antibody (BioLegend, DG9) was used in immunocytochemistry on human samples . Cancer Res (2014) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human
BioLegend perforin antibody (Biolegend, clone dG9) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi
mouse monoclonal (dG9)
  • flow cytometry; human
BioLegend perforin antibody (BioLegend, dG9) was used in flow cytometry on human samples . Clin Cancer Res (2012) ncbi
Invitrogen
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; loading ...; fig 3a
In order to evaluate the role of IL-32alpha in NK cell inhibition, Invitrogen perforin antibody (eBioscience, delta G9) was used in flow cytometry on human samples (fig 3a). J Immunol (2017) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; loading ...; fig 3d
In order to evaluate the effectiveness of adoptive natural killer cell therapy against the pulmonary metastasis of Ewing sarcoma, Invitrogen perforin antibody (eBiosciences, dG9) was used in flow cytometry on human samples (fig 3d). Oncoimmunology (2017) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; loading ...; fig 3e
In order to investigate origin of tumor-infiltrating T regulatory cells in breast cancer samples, Invitrogen perforin antibody (Thermo Fisher Scientific, 12-9994) was used in flow cytometry on human samples (fig 3e). Cell Res (2017) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; loading ...; fig 3b
In order to characterize fetal natural killer cells, Invitrogen perforin antibody (eBioscience, dG9) was used in flow cytometry on human samples (fig 3b). JCI Insight (2017) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; loading ...; fig 1e
In order to characterize gammadelta T cell subsets from healthy humans, Invitrogen perforin antibody (ebioscience, dG9) was used in flow cytometry on human samples (fig 1e). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; loading ...; fig 4a
In order to functionally characterize herpes simplex virus-specific CD8 positive T cells, Invitrogen perforin antibody (eBioscience, d69) was used in flow cytometry on human samples (fig 4a). J Virol (2017) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; fig 5
Invitrogen perforin antibody (eBioscience, gammaG9) was used in flow cytometry on human samples (fig 5). PLoS Pathog (2016) ncbi
mouse monoclonal (5B10)
  • immunohistochemistry - paraffin section; human; loading ...; tbl 3
In order to characterize cases of recurrent panniculitis in children with lipoatrophy, Invitrogen perforin antibody (Thermo Fisher Scientific, 5B10) was used in immunohistochemistry - paraffin section on human samples (tbl 3). J Eur Acad Dermatol Venereol (2017) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; fig 3
In order to study chronic hepatitis C virus infections and the functional dichotomy of V-delta2 gamma-delta T cells and their role in cytotoxicity and not IFN-gamma production, Invitrogen perforin antibody (eBioscience, dG9) was used in flow cytometry on human samples (fig 3). Sci Rep (2016) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; fig 3
Invitrogen perforin antibody (eBioscience, dG9) was used in flow cytometry on human samples (fig 3). J Immunol (2015) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; fig 4
Invitrogen perforin antibody (eBioscience, d69) was used in flow cytometry on human samples (fig 4). J Immunol (2015) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human; fig 4
Invitrogen perforin antibody (eBioscience, d69) was used in flow cytometry on human samples (fig 4). J Virol (2015) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human
In order to developed a strategy to expand umbilical cord blood T cells and test their effects after transplantation, Invitrogen perforin antibody (eBioscience, dG9) was used in flow cytometry on human samples . Leukemia (2015) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human
Invitrogen perforin antibody (eBioscience, dG9) was used in flow cytometry on human samples . Cell Immunol (2014) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; human
In order to determine the role for DOCK8 in peripheral CD8 T cell survival and function, Invitrogen perforin antibody (eBioscience, dG9) was used in flow cytometry on human samples . J Exp Med (2011) ncbi
mouse monoclonal (dG9 (delta G9))
  • flow cytometry; mouse; fig 6
In order to investigate the different immune responses when mice are infected with type I or type II strains of T. gondii, Invitrogen perforin antibody (eBioscience, dG9) was used in flow cytometry on mouse samples (fig 6). J Immunol (2010) ncbi
Abcam
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:25; loading ...; fig 6i
Abcam perforin antibody (Abcam, ab180773) was used in immunohistochemistry - paraffin section on mouse samples at 1:25 (fig 6i). PLoS ONE (2018) ncbi
mouse monoclonal (CE2.10)
  • other; human; 5 ug/ml; loading ...; fig 1b
Abcam perforin antibody (Abcam, CE2.10) was used in other on human samples at 5 ug/ml (fig 1b). J Cell Biol (2018) ncbi
mouse monoclonal (B-D48)
  • mass cytometry; human; loading ...; fig 4f
Abcam perforin antibody (Abcam, B-D48) was used in mass cytometry on human samples (fig 4f). Proc Natl Acad Sci U S A (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3a
Abcam perforin antibody (Abcam, ab180773) was used in western blot on mouse samples at 1:1000 (fig 3a). Exp Ther Med (2016) ncbi
mouse monoclonal (B-D48)
  • flow cytometry; human; loading ...; fig 1
In order to discuss the importance of assessing immune competence in cancer patients, Abcam perforin antibody (Abcam, B-D48) was used in flow cytometry on human samples (fig 1). Cancer Immunol Immunother (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-2)
  • western blot; human; 1:250; fig 5c
Santa Cruz Biotechnology perforin antibody (Santa Cruz, sc-373943) was used in western blot on human samples at 1:250 (fig 5c). J Extracell Vesicles (2017) ncbi
mouse monoclonal (deltaG9)
  • immunocytochemistry; human; fig 3d
In order to discuss the use of natural killer cells for clinical applications, Santa Cruz Biotechnology perforin antibody (Santa Cruz, deltaG9) was used in immunocytochemistry on human samples (fig 3d). Cytotherapy (2017) ncbi
mouse monoclonal (E-5)
  • immunohistochemistry; human
Santa Cruz Biotechnology perforin antibody (Santa Cruz, sc-374346) was used in immunohistochemistry on human samples . Clin Cancer Res (2013) ncbi
MABTECH
mouse monoclonal (Pf-344)
  • flow cytometry; human; fig 1d
  • flow cytometry; Rhesus monkey; fig 6e
In order to identify and characterize CXCR5hiCD44hiCD8 T cells in HIV-infected individuals, MABTECH perforin antibody (Mabtech, 3465-7) was used in flow cytometry on human samples (fig 1d) and in flow cytometry on Rhesus monkey samples (fig 6e). PLoS Pathog (2016) ncbi
mouse monoclonal (Pf-344)
  • flow cytometry; African green monkey; loading ...; fig 1h
In order to discuss the use of flow cytometry to examine common marmosets, MABTECH perforin antibody (Mabtech, Pf-344) was used in flow cytometry on African green monkey samples (fig 1h). J Med Primatol (2016) ncbi
BD Biosciences
mouse monoclonal (G9)
  • flow cytometry; human; fig s9f
In order to explore the role of exhausted CD8 positive CXCR5 positive T cells in mice chronically infected with lymphocytic choriomeningitis virus, BD Biosciences perforin antibody (BD, ??G9) was used in flow cytometry on human samples (fig s9f). Nature (2016) ncbi
mouse monoclonal (G9)
  • immunocytochemistry; human; 10 ug/ml; fig 1
BD Biosciences perforin antibody (BD Pharmingen, dletaG9) was used in immunocytochemistry on human samples at 10 ug/ml (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (G9)
  • immunocytochemistry; human; fig 2
BD Biosciences perforin antibody (BD Pharmingen, 556434) was used in immunocytochemistry on human samples (fig 2). Traffic (2015) ncbi
mouse monoclonal (G9)
  • flow cytometry; human; tbl s2
In order to examine the early impact of viral replicative capacity on HIV-1 immunopathogenesis, BD Biosciences perforin antibody (BD Biosciences, DG9) was used in flow cytometry on human samples (tbl s2). Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (G9)
  • flow cytometry; human; fig 4
In order to describe the phenotype and functional potential of metastatic differentiated thyroid cancer-associated PD-1 positive T cells, BD Biosciences perforin antibody (BD Biosciences, dG9) was used in flow cytometry on human samples (fig 4). Cancer Immunol Res (2015) ncbi
mouse monoclonal (G9)
  • flow cytometry; human; tbl s5
In order to investigate when Vgamma9Vdelta2 T cells develop, BD Biosciences perforin antibody (BD Bioscience, ??G9) was used in flow cytometry on human samples (tbl s5). Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal (G9)
  • flow cytometry; human
In order to examine the effect of lytic EBV antigen-specific CD8+ T cells on EBV infection in humanized mice, BD Biosciences perforin antibody (BD Pharmigen, deltaG9) was used in flow cytometry on human samples . PLoS Pathog (2014) ncbi
mouse monoclonal (G9)
  • immunocytochemistry; human
BD Biosciences perforin antibody (BD Biosciences, deltaG9) was used in immunocytochemistry on human samples . Proc Natl Acad Sci U S A (2014) ncbi
Leica Biosystems
mouse monoclonal (5B10)
  • immunohistochemistry - paraffin section; human; tbl 1
In order to present patient cases of nasal natural killer/T cell tumors in the central nervous system, Leica Biosystems perforin antibody (Novocastra, 5B10) was used in immunohistochemistry - paraffin section on human samples (tbl 1). Histopathology (2017) ncbi
Articles Reviewed
  1. Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed publisher
  2. Ye W, Chew M, Hou J, Lai F, Leopold S, Loo H, et al. Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway. PLoS Pathog. 2018;14:e1007298 pubmed publisher
  3. Kaur G, Helmer R, Smith L, Martinez Zaguilan R, Dufour J, Chilton B. Alternative splicing of helicase-like transcription factor (Hltf): Intron retention-dependent activation of immune tolerance at the feto-maternal interface. PLoS ONE. 2018;13:e0200211 pubmed publisher
  4. Srpan K, Ambrose A, Karampatzakis A, Saeed M, Cartwright A, Guldevall K, et al. Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells. J Cell Biol. 2018;217:3267-3283 pubmed publisher
  5. Galperin M, Farenc C, Mukhopadhyay M, Jayasinghe D, Decroos A, Benati D, et al. CD4+ T cell-mediated HLA class II cross-restriction in HIV controllers. Sci Immunol. 2018;3: pubmed publisher
  6. Herndler Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proc Natl Acad Sci U S A. 2017;114:E9626-E9634 pubmed publisher
  7. Burr M, Sparbier C, Chan Y, Williamson J, Woods K, Beavis P, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. Nature. 2017;549:101-105 pubmed publisher
  8. Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher
  9. Dias J, Leeansyah E, Sandberg J. Multiple layers of heterogeneity and subset diversity in human MAIT cell responses to distinct microorganisms and to innate cytokines. Proc Natl Acad Sci U S A. 2017;114:E5434-E5443 pubmed publisher
  10. Tong A, Hashem H, Eid S, Allen F, Kingsley D, Huang A. Adoptive natural killer cell therapy is effective in reducing pulmonary metastasis of Ewing sarcoma. Oncoimmunology. 2017;6:e1303586 pubmed publisher
  11. Miyata Takata T, Takata K, Kato S, Hu L, Noujima Harada M, Chuang S, et al. Clinicopathological analysis of primary central nervous system NK/T cell lymphoma: rare and localized aggressive tumour among extranasal NK/T cell tumours. Histopathology. 2017;71:287-295 pubmed publisher
  12. Jong A, Wu C, Li J, Sun J, Fabbri M, Wayne A, et al. Large-scale isolation and cytotoxicity of extracellular vesicles derived from activated human natural killer cells. J Extracell Vesicles. 2017;6:1294368 pubmed publisher
  13. Su S, Liao J, Liu J, Huang D, He C, Chen F, et al. Blocking the recruitment of naive CD4+ T cells reverses immunosuppression in breast cancer. Cell Res. 2017;27:461-482 pubmed publisher
  14. Collins A, Rothman N, Liu K, Reiner S. Eomesodermin and T-bet mark developmentally distinct human natural killer cells. JCI Insight. 2017;2:e90063 pubmed publisher
  15. Cheuk S, Schlums H, Gallais Sérézal I, Martini E, Chiang S, Marquardt N, et al. CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin. Immunity. 2017;46:287-300 pubmed publisher
  16. Mordmuller B, Surat G, Lagler H, Chakravarty S, Ishizuka A, Lalremruata A, et al. Sterile protection against human malaria by chemoattenuated PfSPZ vaccine. Nature. 2017;542:445-449 pubmed publisher
  17. Sun Y, Guo M, Feng Y, Zheng H, Lei P, Ma X, et al. Effect of ginseng polysaccharides on NK cell cytotoxicity in immunosuppressed mice. Exp Ther Med. 2016;12:3773-3777 pubmed publisher
  18. Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren H, Sonnerborg A, et al. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. Sci Rep. 2017;7:40354 pubmed publisher
  19. Ryan P, Sumaria N, Holland C, Bradford C, Izotova N, Grandjean C, et al. Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals. Proc Natl Acad Sci U S A. 2016;113:14378-14383 pubmed
  20. Oelsner S, Friede M, Zhang C, Wagner J, Badura S, Bader P, et al. Continuously expanding CAR NK-92 cells display selective cytotoxicity against B-cell leukemia and lymphoma. Cytotherapy. 2017;19:235-249 pubmed publisher
  21. Srivastava R, Khan A, Garg S, Syed S, Furness J, Vahed H, et al. Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocula. J Virol. 2017;91: pubmed publisher
  22. Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed
  23. Miles B, Miller S, Folkvord J, Levy D, Rakasz E, Skinner P, et al. Follicular Regulatory CD8 T Cells Impair the Germinal Center Response in SIV and Ex Vivo HIV Infection. PLoS Pathog. 2016;12:e1005924 pubmed publisher
  24. Pachnio A, Ciáurriz M, Begum J, Lal N, Zuo J, Beggs A, et al. Cytomegalovirus Infection Leads to Development of High Frequencies of Cytotoxic Virus-Specific CD4+ T Cells Targeted to Vascular Endothelium. PLoS Pathog. 2016;12:e1005832 pubmed publisher
  25. Torrelo A, Noguera Morel L, Hernandez Martin A, Clemente D, Barja J, Buzon L, et al. Recurrent lipoatrophic panniculitis of children. J Eur Acad Dermatol Venereol. 2017;31:536-543 pubmed publisher
  26. He R, Hou S, Liu C, Zhang A, Bai Q, Han M, et al. Follicular CXCR5- expressing CD8(+) T cells curtail chronic viral infection. Nature. 2016;537:412-428 pubmed publisher
  27. Demers K, Makedonas G, Buggert M, Eller M, Ratcliffe S, Goonetilleke N, et al. Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection. PLoS Pathog. 2016;12:e1005805 pubmed publisher
  28. Suliman S, Geldenhuys H, Johnson J, Hughes J, Smit E, Murphy M, et al. Bacillus Calmette-Guérin (BCG) Revaccination of Adults with Latent Mycobacterium tuberculosis Infection Induces Long-Lived BCG-Reactive NK Cell Responses. J Immunol. 2016;197:1100-1110 pubmed publisher
  29. Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed publisher
  30. Yin W, Tong S, Zhang Q, Shao J, Liu Q, Peng H, et al. Functional dichotomy of Vδ2 γδ T cells in chronic hepatitis C virus infections: role in cytotoxicity but not for IFN-γ production. Sci Rep. 2016;6:26296 pubmed publisher
  31. Khazen R, Müller S, Gaudenzio N, Espinosa E, Puissegur M, Valitutti S. Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse. Nat Commun. 2016;7:10823 pubmed publisher
  32. Roan F, Stoklasek T, Whalen E, Molitor J, Bluestone J, Buckner J, et al. CD4+ Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis. J Immunol. 2016;196:2051-2062 pubmed publisher
  33. Dieckmann N, Hackmann Y, Aricò M, Griffiths G. Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes. Traffic. 2015;16:1330-41 pubmed publisher
  34. Zhang Z, Wu N, Lu Y, Davidson D, Colonna M, Veillette A. DNAM-1 controls NK cell activation via an ITT-like motif. J Exp Med. 2015;212:2165-82 pubmed publisher
  35. Rosario M, Liu B, Kong L, Collins L, Schneider S, Chen X, et al. The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas. Clin Cancer Res. 2016;22:596-608 pubmed publisher
  36. Leeansyah E, Svärd J, Dias J, Buggert M, Nyström J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed publisher
  37. Claiborne D, Prince J, Scully E, Macharia G, Micci L, Lawson B, et al. Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Proc Natl Acad Sci U S A. 2015;112:E1480-9 pubmed publisher
  38. Severson J, Serracino H, Mateescu V, Raeburn C, McIntyre R, Sams S, et al. PD-1+Tim-3+ CD8+ T Lymphocytes Display Varied Degrees of Functional Exhaustion in Patients with Regionally Metastatic Differentiated Thyroid Cancer. Cancer Immunol Res. 2015;3:620-30 pubmed publisher
  39. Marquardt N, Béziat V, Nyström S, Hengst J, Ivarsson M, Kekäläinen E, et al. Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells. J Immunol. 2015;194:2467-71 pubmed publisher
  40. Srivastava R, Khan A, Spencer D, Vahed H, Lopes P, Thai N, et al. HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic. J Immunol. 2015;194:2232-48 pubmed publisher
  41. Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher
  42. Khan A, Srivastava R, Spencer D, Garg S, Fremgen D, Vahed H, et al. Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes. J Virol. 2015;89:3776-92 pubmed publisher
  43. Zhang P, Lu X, Tao K, Shi L, Li W, Wang G, et al. Siglec-10 is associated with survival and natural killer cell dysfunction in hepatocellular carcinoma. J Surg Res. 2015;194:107-13 pubmed publisher
  44. Ziblat A, Domaica C, Spallanzani R, Iraolagoitia X, Rossi L, Avila D, et al. IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness. Eur J Immunol. 2015;45:192-202 pubmed publisher
  45. Antsiferova O, Müller A, Rämer P, Chijioke O, Chatterjee B, Raykova A, et al. Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice. PLoS Pathog. 2014;10:e1004333 pubmed publisher
  46. Pegram H, Purdon T, van Leeuwen D, Curran K, Giralt S, Barker J, et al. IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia. Leukemia. 2015;29:415-22 pubmed publisher
  47. Jiang B, Wu X, Li X, Yang X, Zhou Y, Yan H, et al. Expansion of NK cells by engineered K562 cells co-expressing 4-1BBL and mMICA, combined with soluble IL-21. Cell Immunol. 2014;290:10-20 pubmed publisher
  48. Mace E, Orange J. Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A. Proc Natl Acad Sci U S A. 2014;111:6708-13 pubmed publisher
  49. Peguillet I, Milder M, Louis D, Vincent Salomon A, Dorval T, Piperno Neumann S, et al. High numbers of differentiated effector CD4 T cells are found in patients with cancer and correlate with clinical response after neoadjuvant therapy of breast cancer. Cancer Res. 2014;74:2204-16 pubmed publisher
  50. Poonia B, Pauza C. Levels of CD56+TIM-3- effector CD8 T cells distinguish HIV natural virus suppressors from patients receiving antiretroviral therapy. PLoS ONE. 2014;9:e88884 pubmed publisher
  51. Chang S, Kohrt H, Maecker H. Monitoring the immune competence of cancer patients to predict outcome. Cancer Immunol Immunother. 2014;63:713-9 pubmed publisher
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