This is a Validated Antibody Database (VAD) review about human lysosomal acid lipase, based on 3 published articles (read how Labome selects the articles), using lysosomal acid lipase antibody in all methods. It is aimed to help Labome visitors find the most suited lysosomal acid lipase antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
lysosomal acid lipase synonym: CESD; LAL

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (9G7F12)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig e7d
  • western blot knockout validation; human; 1:1000; loading ...; fig e4h, 5k, e8b
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 6a, 6b, e7d
Santa Cruz Biotechnology lysosomal acid lipase antibody (Santa Cruz, sc-58374) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig e7d), in western blot knockout validation on human samples at 1:1000 (fig e4h, 5k, e8b) and in immunohistochemistry - paraffin section on human samples at 1:200 (fig 6a, 6b, e7d). Nat Cancer (2022) ncbi
Santa Cruz Biotechnology
mouse monoclonal (9G7F12)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig e7d
  • western blot knockout validation; human; 1:1000; loading ...; fig e4h, 5k, e8b
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 6a, 6b, e7d
Santa Cruz Biotechnology lysosomal acid lipase antibody (Santa Cruz, sc-58374) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig e7d), in western blot knockout validation on human samples at 1:1000 (fig e4h, 5k, e8b) and in immunohistochemistry - paraffin section on human samples at 1:200 (fig 6a, 6b, e7d). Nat Cancer (2022) ncbi
mouse monoclonal (9G7F12)
  • western blot; mouse; loading ...; fig 4d
In order to investigate the mechanism for adoptively transferred effector T-cell survival and memory formation, Santa Cruz Biotechnology lysosomal acid lipase antibody (Santa Cruz, 9G7F12) was used in western blot on mouse samples (fig 4d). Cell Biosci (2016) ncbi
mouse monoclonal
  • western blot; mouse; loading ...; fig 4d
In order to investigate the mechanism for adoptively transferred effector T-cell survival and memory formation, Santa Cruz Biotechnology lysosomal acid lipase antibody (Santa Cruz, 9G7F12) was used in western blot on mouse samples (fig 4d). Cell Biosci (2016) ncbi
Invitrogen
mouse monoclonal (9G7F12,7G6D7)
  • western blot; human; loading ...; fig 2a
In order to evaluate stem cell-based disease model for Wolman disease, Invitrogen lysosomal acid lipase antibody (ThermoFisher, MA5-15278) was used in western blot on human samples (fig 2a). Orphanet J Rare Dis (2017) ncbi
Articles Reviewed
  1. Liu X, Viswanadhapalli S, Kumar S, Lee T, Moore A, Ma S, et al. Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress. Nat Cancer. 2022;: pubmed publisher
  2. Aguisanda F, Yeh C, Chen C, Li R, Beers J, Zou J, et al. Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics. Orphanet J Rare Dis. 2017;12:120 pubmed publisher
  3. Xu A, Bhanumathy K, Wu J, Ye Z, Freywald A, Leary S, et al. IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia. Cell Biosci. 2016;6:30 pubmed publisher