This is a Validated Antibody Database (VAD) review about human loricrin, based on 10 published articles (read how Labome selects the articles), using loricrin antibody in all methods. It is aimed to help Labome visitors find the most suited loricrin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
loricrin synonym: LOR

BioLegend
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry - frozen section; mouse; 1:2000; loading ...; fig 4s1c
BioLegend loricrin antibody (Covance, PRB-145P) was used in immunohistochemistry - frozen section on mouse samples at 1:2000 (fig 4s1c). elife (2019) ncbi
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig s5e
BioLegend loricrin antibody (BioLegend, 905104) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig s5e). Nat Med (2018) ncbi
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3d
  • western blot; mouse; loading ...; fig 3e
In order to understand the role of AP1 transcription factor in ichthyoses and collodion membrane formation, BioLegend loricrin antibody (Covance, PRB-145P) was used in immunohistochemistry - paraffin section on mouse samples (fig 3d) and in western blot on mouse samples (fig 3e). J Invest Dermatol (2017) ncbi
domestic rabbit polyclonal (Poly19051)
  • other; mouse; 1:200; loading ...; fig 3a
  • western blot; mouse; 1:1000; loading ...; fig 3b
BioLegend loricrin antibody (Corvance, PRB-145P) was used in other on mouse samples at 1:200 (fig 3a) and in western blot on mouse samples at 1:1000 (fig 3b). Sci Rep (2017) ncbi
domestic rabbit polyclonal (Poly19051)
  • western blot; human; 1:1000; loading ...; fig 2c
In order to discuss mutations that contribute to atopic dermatitis, BioLegend loricrin antibody (Covance, PRB-145P) was used in western blot on human samples at 1:1000 (fig 2c). J Allergy Clin Immunol (2017) ncbi
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry; mouse; loading ...; fig 3b
In order to generate and characterize mice that lack CD44 in the skin, BioLegend loricrin antibody (Covance, PRB-145P) was used in immunohistochemistry on mouse samples (fig 3b). Cell Death Dis (2016) ncbi
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig S5B
In order to show that deletion of the gene encoding RAB guanine nucleotide exchange factor 1 in keratinocytes severely impairs epidermal barrier function in mice, BioLegend loricrin antibody (Covance, PRB-145P) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig S5B). J Clin Invest (2016) ncbi
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry; human; 1:2000; fig 1a
In order to demonstrate that epidermal equivalents of filaggrin null keratinocytes do not have impaired skin barrier function, BioLegend loricrin antibody (Covance, PRB145P) was used in immunohistochemistry on human samples at 1:2000 (fig 1a). J Allergy Clin Immunol (2017) ncbi
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry - paraffin section; mouse; 1:250; fig 4C
BioLegend loricrin antibody (Covance, PRB-145P) was used in immunohistochemistry - paraffin section on mouse samples at 1:250 (fig 4C). Stem Cell Res Ther (2016) ncbi
domestic rabbit polyclonal (Poly19051)
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1
BioLegend loricrin antibody (Covance, PRB-145P) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1). J Cell Biol (2016) ncbi
Articles Reviewed
  1. Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed publisher
  2. Zhang Z, Zi Z, Lee E, Zhao J, Contreras D, South A, et al. Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis. Nat Med. 2018;24:617-627 pubmed publisher
  3. Young C, Eckert R, Adhikary G, Crumrine D, Elias P, Blumenberg M, et al. Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like Phenotype. J Invest Dermatol. 2017;137:1868-1877 pubmed publisher
  4. Shin J, Choi D, Sohn K, Kim J, Im M, Lee Y, et al. Targeted deletion of Crif1 in mouse epidermis impairs skin homeostasis and hair morphogenesis. Sci Rep. 2017;7:44828 pubmed publisher
  5. Naeem A, Tommasi C, Cole C, Brown S, Zhu Y, Way B, et al. A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic d. J Allergy Clin Immunol. 2017;139:1228-1241 pubmed publisher
  6. Shatirishvili M, Burk A, Franz C, Pace G, Kastilan T, Breuhahn K, et al. Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress. Cell Death Dis. 2016;7:e2461 pubmed publisher
  7. Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
  8. Niehues H, Schalkwijk J, van Vlijmen Willems I, Rodijk Olthuis D, van Rossum M, Wladykowski E, et al. Epidermal equivalents of filaggrin null keratinocytes do not show impaired skin barrier function. J Allergy Clin Immunol. 2017;139:1979-1981.e13 pubmed publisher
  9. Iacovides D, Rizki G, Lapathitis G, Strati K. Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes. Stem Cell Res Ther. 2016;7:98 pubmed publisher
  10. Mardaryev A, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, et al. Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016;212:77-89 pubmed publisher