This is a Validated Antibody Database (VAD) review about human leptin receptor, based on 15 published articles (read how Labome selects the articles), using leptin receptor antibody in all methods. It is aimed to help Labome visitors find the most suited leptin receptor antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
leptin receptor synonym: CD295; LEP-R; LEPRD; OB-R; OBR; leptin receptor; OB receptor; huB219

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (B-3)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 1
Santa Cruz Biotechnology leptin receptor antibody (Santa Cruz Biotechnology, sc8391) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1). Mol Metab (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-3)
  • western blot; mouse; 1:1000; loading ...; fig 10
Santa Cruz Biotechnology leptin receptor antibody (SantaCruz, sc-8391) was used in western blot on mouse samples at 1:1000 (fig 10). Am J Physiol Regul Integr Comp Physiol (2017) ncbi
mouse monoclonal (B-3)
  • western blot; human; fig 2
Santa Cruz Biotechnology leptin receptor antibody (Santa Cruz Biotechnology, sc-8391) was used in western blot on human samples (fig 2). Arthritis Res Ther (2016) ncbi
mouse monoclonal (B-3)
  • immunoprecipitation; mouse; fig 7
  • western blot; mouse; 1:1000; fig 7
Santa Cruz Biotechnology leptin receptor antibody (Santa Cruz, sc-8391) was used in immunoprecipitation on mouse samples (fig 7) and in western blot on mouse samples at 1:1000 (fig 7). PLoS Genet (2016) ncbi
mouse monoclonal (B-3)
  • immunohistochemistry; human; 1:25; loading ...; fig 1b
  • western blot; human; 1:500; loading ...; fig 3
Santa Cruz Biotechnology leptin receptor antibody (Santa Cruz, sc-8391) was used in immunohistochemistry on human samples at 1:25 (fig 1b) and in western blot on human samples at 1:500 (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (B-3)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 1
Santa Cruz Biotechnology leptin receptor antibody (Santa Cruz Biotechnology, sc8391) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 1). Mol Metab (2014) ncbi
mouse monoclonal (B-3)
  • immunohistochemistry; human; fig 2
Santa Cruz Biotechnology leptin receptor antibody (santa cruz, sc-8391) was used in immunohistochemistry on human samples (fig 2). Reprod Sci (2015) ncbi
R&D Systems
mouse monoclonal (52263)
  • flow cytometry; human; fig st1
In order to find cell-surface markers specific to human neutrophils, R&D Systems leptin receptor antibody (R&D Systems, FAB867P) was used in flow cytometry on human samples (fig st1). Exp Cell Res (2016) ncbi
goat polyclonal
  • immunohistochemistry - frozen section; human; 1:40; fig 3
R&D Systems leptin receptor antibody (r&D systems, AF389) was used in immunohistochemistry - frozen section on human samples at 1:40 (fig 3). PLoS ONE (2015) ncbi
mouse monoclonal (52263)
  • flow cytometry; human; fig s4
R&D Systems leptin receptor antibody (R&D Systems, FAB867P) was used in flow cytometry on human samples (fig s4). Stem Cell Reports (2015) ncbi
mouse monoclonal (52263)
  • flow cytometry; human
R&D Systems leptin receptor antibody (R&D Systems, 52263) was used in flow cytometry on human samples . Physiol Rep (2014) ncbi
Abcam
rabbit polyclonal
  • western blot; human; 1:2000; fig 3
Abcam leptin receptor antibody (abcam, ab5593) was used in western blot on human samples at 1:2000 (fig 3). Cancer Chemother Pharmacol (2016) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig st3
In order to study the contribution of SFMBT2 to prostate cancer metastasis, Abcam leptin receptor antibody (Abcam, ab7212) was used in western blot on human samples (fig st3). Oncotarget (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 3
Abcam leptin receptor antibody (abcam, ab5593) was used in western blot on rat samples (fig 3). Int J Mol Sci (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 6c
Abcam leptin receptor antibody (Abcam, ab5593) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 6c). PLoS ONE (2015) ncbi
BD Biosciences
mouse monoclonal (52263)
  • flow cytometry; human; 1:20; loading ...; fig 2f
BD Biosciences leptin receptor antibody (BD Pharmingen, 564376) was used in flow cytometry on human samples at 1:20 (fig 2f). Nat Neurosci (2018) ncbi
Articles Reviewed
  1. Karow M, Camp J, Falk S, Gerber T, Pataskar A, Gac Santel M, et al. Direct pericyte-to-neuron reprogramming via unfolding of a neural stem cell-like program. Nat Neurosci. 2018;21:932-940 pubmed publisher
  2. Yi X, Gao H, Chen D, Tang D, Huang W, Li T, et al. Effects of obesity and exercise on testicular leptin signal transduction and testosterone biosynthesis in male mice. Am J Physiol Regul Integr Comp Physiol. 2017;312:R501-R510 pubmed publisher
  3. Malaise O, Relic B, Charlier E, Zeddou M, Neuville S, Deroyer C, et al. Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts. Arthritis Res Ther. 2016;18:219 pubmed
  4. Fiedor E, Gregoraszczuk E. The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines. Cancer Chemother Pharmacol. 2016;78:611-22 pubmed publisher
  5. Gwak J, Shin J, Lee K, Hong S, Oh S, Goh S, et al. SFMBT2 (Scm-like with four mbt domains 2) negatively regulates cell migration and invasion in prostate cancer cells. Oncotarget. 2016;7:48250-48264 pubmed publisher
  6. Huang Y, Chen C, Tang K, Sheen J, Tiao M, Tain Y, et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci. 2016;17:369 pubmed publisher
  7. Lakschevitz F, Hassanpour S, Rubin A, Fine N, Sun C, Glogauer M. Identification of neutrophil surface marker changes in health and inflammation using high-throughput screening flow cytometry. Exp Cell Res. 2016;342:200-9 pubmed publisher
  8. Guo D, Cui H, Zhang Q, Morgan D, Thedens D, Nishimura D, et al. The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane. PLoS Genet. 2016;12:e1005890 pubmed publisher
  9. Basu S, Combe K, Kwiatkowski F, Caldefie Chézet F, Penault Llorca F, Bignon Y, et al. Cellular Expression of Cyclooxygenase, Aromatase, Adipokines, Inflammation and Cell Proliferation Markers in Breast Cancer Specimen. PLoS ONE. 2015;10:e0138443 pubmed publisher
  10. Ramirez H, Liang L, Pastar I, Rosa A, Stojadinovic O, Zwick T, et al. Comparative Genomic, MicroRNA, and Tissue Analyses Reveal Subtle Differences between Non-Diabetic and Diabetic Foot Skin. PLoS ONE. 2015;10:e0137133 pubmed publisher
  11. Choi E, Byeon S, Kim S, Lee H, Kwon H, Ahn H, et al. Implication of Leptin-Signaling Proteins and Epstein-Barr Virus in Gastric Carcinomas. PLoS ONE. 2015;10:e0130839 pubmed publisher
  12. James S, Fox J, Afsari F, Lee J, Clough S, Knight C, et al. Multiparameter Analysis of Human Bone Marrow Stromal Cells Identifies Distinct Immunomodulatory and Differentiation-Competent Subtypes. Stem Cell Reports. 2015;4:1004-15 pubmed publisher
  13. Cannon J, Sharma G, Sloan G, Dimitropoulou C, Baker R, Mazzoli A, et al. Leptin regulates CD16 expression on human monocytes in a sex-specific manner. Physiol Rep. 2014;2: pubmed publisher
  14. de Lartigue G, Ronveaux C, Raybould H. Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity. Mol Metab. 2014;3:595-607 pubmed publisher
  15. Tsai P, Davis J, Bryant Greenwood G. Systemic and placental leptin and its receptors in pregnancies associated with obesity. Reprod Sci. 2015;22:189-97 pubmed publisher