This is a Validated Antibody Database (VAD) review about human granzyme B, based on 303 published articles (read how Labome selects the articles), using granzyme B antibody in all methods. It is aimed to help Labome visitors find the most suited granzyme B antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
granzyme B synonym: C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT
Invitrogen
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Thermo Fisher, MA1-80734) was used in flow cytometry on mouse samples . Cancer Cell (2021) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on mouse samples at 1:100 (fig 5a). Nat Commun (2021) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (eBioscience, GB11) was used in flow cytometry on mouse samples at 1:200. Nat Commun (2021) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Thermo Fisher, MHGB04) was used in flow cytometry on mouse samples (fig 7j). Cell Rep Med (2021) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Thermo Fisher, MHGB05) was used in flow cytometry on mouse samples at 1:100 (fig s7b). Science (2021) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Thermo Scientific, MA1-80734) was used in immunocytochemistry on human samples at 10 ug/ml (fig 6v1). elife (2021) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Thermo Fisher Scientific, GB12) was used in flow cytometry on mouse samples at 1:100. elife (2020) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Invitrogen, GRB18) was used in flow cytometry on human samples at 1:2000. bioRxiv (2020) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Thermo, GRB17) was used in flow cytometry on human samples at 1:40 (fig 2s1). elife (2020) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (eBioscience, GB11) was used in flow cytometry on human samples (fig 4a). BMC Immunol (2020) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Thermofisher, GRB17) was used in flow cytometry on mouse samples (fig 2f). Immunity (2019) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Invitrogen, GRB18) was used in flow cytometry on mouse samples (fig s4f). Cell (2019) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (ThermoFisher Scientific, MA1-80734) was used in other on human samples at 1:25 (fig 2f). elife (2019) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on human samples (fig s1g). Cell (2019) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on mouse samples (fig 6f). PLoS Pathog (2018) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Thermo Fisher, GB11) was used in flow cytometry on human samples (fig 2f). Front Immunol (2018) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 4b). J Virol (2018) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (eBioscience, GB11) was used in flow cytometry on human samples (fig 3b). J Exp Med (2018) ncbi |
| mouse monoclonal (GB12) |
| In order to study the involvement of Notch signaling in NK cell lineage determination, Invitrogen granzyme B antibody (invitrogen, GB12) was used in flow cytometry on human samples (fig 1b). J Immunol (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to evaluate the role of IL-32alpha in NK cell inhibition, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on human samples (fig 3a). J Immunol (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to evaluate the effectiveness of adoptive natural killer cell therapy against the pulmonary metastasis of Ewing sarcoma, Invitrogen granzyme B antibody (eBiosciences, GB11) was used in flow cytometry on human samples (fig 3d). Oncoimmunology (2017) ncbi |
| mouse monoclonal (GB12) |
| In order to find that TLR3, 7 and 9 deficiencies on host cells result in complete tumor regression and induction of anti-tumor immunity, Invitrogen granzyme B antibody (Life Technologies, GB12) was used in flow cytometry on mouse samples (fig 5b). Nat Commun (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate origin of tumor-infiltrating T regulatory cells in breast cancer samples, Invitrogen granzyme B antibody (Thermo fischer scientific, 12-8899) was used in flow cytometry on human samples (fig 3f). Cell Res (2017) ncbi |
| mouse monoclonal (GB12) |
| In order to optimize the dosing regimen of neutralizing anti-HIV-1 antibodies, Invitrogen granzyme B antibody (invitrogen, GB12) was used in flow cytometry on African green monkey samples (fig s4). Nature (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to use CD49a expression to define subsets of tissue-resident memory T cells in the skin, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on human samples (fig 3a). Immunity (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to evaluate the use of a recombinant Newcastle disease virus expressing ICOS ligand to treat cancer, Invitrogen granzyme B antibody (Invitrogen, GRB05) was used in flow cytometry on mouse samples at 1:125 (fig 3h). Nat Commun (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate the mechanisms by which eomesodermin regulates memory fitness in T cells, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 6m). Proc Natl Acad Sci U S A (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the potential of IL-2 to enhance T regulatory cell therapy, Invitrogen granzyme B antibody (eBioscience, GB11) was used in flow cytometry on human samples (fig 3c). Clin Exp Immunol (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to show T cell immunoglobulin and ITIM domain expression increases over time despite early initiation of antiretroviral treatment, Invitrogen granzyme B antibody (LifeTechnologies/Invitrogen, GB11) was used in flow cytometry on human samples . Sci Rep (2017) ncbi |
| mouse monoclonal (GB12) |
| In order to discuss the assessment of species cross-reactive human agents in large animal graft-versus-host disease models, Invitrogen granzyme B antibody (Invitrogen, MHGB05) was used in flow cytometry on rhesus macaque samples (fig 6d). Transplantation (2016) ncbi |
| mouse monoclonal (GB12) |
| In order to examine the contribution of HIV-derived conserved elements in vaccination, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on rhesus macaque samples (fig 4d). J Immunol (2016) ncbi |
| mouse monoclonal (GB12) |
| In order to characterize CD8 positive T cell subsets in dengue patients from India and Thailand, Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on human samples (fig 4a). J Virol (2016) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the contribution of TGF-beta to the eomesodermin-driven CD4 T cell program during viral infection, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 5f). J Clin Invest (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to study the functions of WASp knock out natural killer cells, Invitrogen granzyme B antibody (Invitrogen, GRB17) was used in flow cytometry on human samples (fig 7). Sci Rep (2016) ncbi |
| domestic rabbit polyclonal |
| In order to investigate the functions of EZH2 in human T cells, Invitrogen granzyme B antibody (Thermo, PA5-17457) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 3). Cell Death Dis (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to assess the contribution of interferon-induced transmembrane protein 3 to West Nile virus infection, Invitrogen granzyme B antibody (Invitrogen, GRB04) was used in flow cytometry on mouse samples (fig 4i). J Virol (2016) ncbi |
| mouse monoclonal (GZB01) |
| In order to characterize anti-GABAB receptor limbic encephalitis and evidence of a pathogenic role for CD8(+) T cells, Invitrogen granzyme B antibody (Thermo, MS-1157-S1) was used in immunohistochemistry on human samples at 1:50 (fig 3). Neurol Neuroimmunol Neuroinflamm (2016) ncbi |
| mouse monoclonal (GB12) |
| In order to elucidate the marked reduction of Nkp44/Nkp46-double positive natural killer cells by celiac disease-related inflammation, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on human samples at 1:100 (fig 3). PLoS ONE (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize mediation of anti-viral cytotoxicity by type 1 interferon licenses naive CD8 T cells, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 1). Virology (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the contribution of Foxo1 to activated T cells, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples . Nature (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate restriction of west nile virus infection and pathogenesis in a region-specific and cell-type manner by the interferon-stimulated gene Ifi2712a, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples at 1:50 (fig 5). J Virol (2015) ncbi |
| rat monoclonal (16G6) |
| Invitrogen granzyme B antibody (eBioscience, 16G6) was used in western blot on human samples (fig 2c). J Biol Chem (2016) ncbi |
| mouse monoclonal (GZB01) |
| In order to compare multiple sclerosis to autoimmune encephalitis in humans, Invitrogen granzyme B antibody (Neomarkers, MS-1157-S) was used in immunohistochemistry - paraffin section on human samples at 1:1000. Acta Neuropathol Commun (2015) ncbi |
| rat monoclonal (16G6) |
| In order to study PI3Kdelta in CD8+ T cells during infection with Listeria monocytogenes, Invitrogen granzyme B antibody (eBioscience, 16G6) was used in flow cytometry on mouse samples . J Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to test if anti-retroviral natural killer cell functions are inhibited by T regulatory cells during an acute Friend retrovirus infection, Invitrogen granzyme B antibody (Life technologies, GB11) was used in flow cytometry on mouse samples (fig 2f). Retrovirology (2015) ncbi |
| mouse monoclonal (GB12) |
| In order to evaluate as a mucosal vaccine platform against influenza A virus, Invitrogen granzyme B antibody (Invitrogen, #MHGB05) was used in flow cytometry on human samples (fig 5). Front Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to determine if therapeutic antiviral T cells eliminate viral load in the brain of mice persistently infected from birth with lymphocytic choriomeningitis virus without causing blood-brain barrier breakdown or tissue damage, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 10a). J Exp Med (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to study engineered anti-melanoma vaccines that modulate cytokine priming and silence PD-L1 simultaneously by use of ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy, Invitrogen granzyme B antibody (Invitrogen, GRB05) was used in flow cytometry on mouse samples (fig 2). Oncoimmunology (2014) ncbi |
| mouse monoclonal (GZB01) |
| In order to describe the clinicopathological features of 15 patients with Epstein-Barr virus-positive nodal T/NK-cell lymphoma, Invitrogen granzyme B antibody (Thermo Scientific, GZB01) was used in immunohistochemistry - paraffin section on human samples . Hum Pathol (2015) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the differentiation and function of murine gamma-herpesvirus 68 (MHV-68)-specific CD4(+) T cells using gp150-specific TCR-transgenic mice, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples . J Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate the role of granzyme B in T regulatory cell resistance, Invitrogen granzyme B antibody (eBioscience, GB11) was used in flow cytometry on human samples (fig 1). J Immunol (2015) ncbi |
| mouse monoclonal (GB12) |
| Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples . Cancer Immunol Res (2015) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (eBioscience, GB11) was used in flow cytometry on dogs samples . Vet Res Commun (2015) ncbi |
| mouse monoclonal (GB12) |
| In order to study CD4 and CD8 responses to L. monocytogenes using GZMB-Tom knock-in mice, Invitrogen granzyme B antibody (Invitrogen, MHGB05) was used in flow cytometry on mouse samples . Immunology (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the role of GPR18 in intestinal intraepithelial lymphocytes, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples . J Exp Med (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate the effect of SGI-110 on cancer testis antigen gene-regulated expression, Invitrogen granzyme B antibody (Invitrogen, clone GB11) was used in flow cytometry on human samples (fig 5). Leuk Res (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to determine virus-induced immune suppression of CD8 T cell responses caused by out-of-sequence signal 3, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 7). PLoS Pathog (2014) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the role of T reg cells in exhaustion of lymphocytic choriomeningitis virus-specific CD8 T cells, Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on mouse samples . J Exp Med (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to show that MID1 regulates cytotoxic lymphocytes responses, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 2). Eur J Immunol (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to developed a strategy to expand umbilical cord blood T cells and test their effects after transplantation, Invitrogen granzyme B antibody (eBioscience, GB11) was used in flow cytometry on human samples . Leukemia (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate incomplete immunity against intracellular pathogens in neonates, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples . J Immunol (2014) ncbi |
| mouse monoclonal (GB12) |
| In order to study the role of human endogenous retrovirus (HERV) envelope proteins in the uptake of exosomes, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples . FASEB J (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize early inflammation at the feeding site of infected sand flies in mice protected from vector-transmitted Leishmania major by exposure to uninfected bites, Invitrogen granzyme B antibody (Invitrogen, GRB05) was used in flow cytometry on mouse samples . PLoS Negl Trop Dis (2014) ncbi |
| mouse monoclonal (GB12) |
| In order to demonstrate that CTLA-4 promotes Tc17 differentiation and robust Tc17 responses, Invitrogen granzyme B antibody (Caltag Laboratories, MHGB04) was used in flow cytometry on mouse samples . Eur J Immunol (2014) ncbi |
| mouse monoclonal (GB12) |
| In order to study the effect of FTY720 treatment on CD8 T-cells, Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on mouse samples . J Neuroimmunol (2014) ncbi |
| mouse monoclonal (GB12) |
| In order to quantify coexpression of different killer Ig-like molecules in patient natural killer cells with mutant TAP genes mediating deficient HLA class I expression, Invitrogen granzyme B antibody (Invitrogen, FGB12) was used in flow cytometry on human samples . J Immunol (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to assess T regulatory type 1 cell therapy in patients with high-risk/advanced stage hematologic malignancies, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on human samples . Front Immunol (2014) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Invitrogen, clone GB11) was used in flow cytometry on human samples . PLoS ONE (2014) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the effect of CpG and IL-21 treatment on B-cell chronic lymphocytic leukemia, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on human samples . Int Immunol (2014) ncbi |
| mouse monoclonal (GB12) |
| In order to compare vaccination with highly conserved gag elements verses full-length gag DNA, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on rhesus macaque samples . PLoS ONE (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize the Treg populations the Friend retrovirus mouse model, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples . Virol Sin (2014) ncbi |
| mouse monoclonal (GB11) |
| Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples . J Immunol (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to identify ADP-ribosylation factor-like 8b as a factor required for natural killer cell-mediated cytotoxicity, Invitrogen granzyme B antibody (Caltag, GB11) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Mol Biol Cell (2013) ncbi |
| mouse monoclonal (GB11) |
| In order to optimize the CD8 T cell-inducing capacity of modified vaccinia Ankara, Invitrogen granzyme B antibody (Life Technologies, GRB04) was used in flow cytometry on mouse samples . Front Immunol (2013) ncbi |
| mouse monoclonal (GB12) |
| In order to examine the functional effects of regulatory T cells during A2-strain respiratory syncytial virus infection, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 2). J Virol (2013) ncbi |
| mouse monoclonal (GB12) |
| In order to assess the role of aryl hydrocarbon receptor nuclear translocator in intestinal intraepithelial T cells development, Invitrogen granzyme B antibody (Life Technologies, MHGB05) was used in flow cytometry on mouse samples (fig 1). Nat Commun (2013) ncbi |
| mouse monoclonal (GB11) |
| In order to report that FoxO1 regulates effector-to-memory transition and functional maturation of memory CD4 and CD8 T cells, Invitrogen granzyme B antibody (Invitrogen, clone GB11) was used in flow cytometry on mouse samples (fig 2). J Immunol (2013) ncbi |
| mouse monoclonal (GB11) |
| In order to determine the generation, phenotype, and function of IL-10-producing CD8(+) T cells in mice infected with murine gamma-herpesvirus-68, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 5). J Immunol (2013) ncbi |
| mouse monoclonal (GZB01) |
| In order to investigate the mechanisms that lead to demyelination and neurodegeneration, Invitrogen granzyme B antibody (Neomarkers, MS-1157-S) was used in immunohistochemistry - paraffin section on human samples at 1:1000. Brain (2013) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate the suppressive activity of Tregs on effector CD4(+) T cells in retroviral infection, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 4). J Virol (2013) ncbi |
| mouse monoclonal (GB12) |
| In order to conclude that increased detection of granzyme B in cytotoxic T cells and natural killer cells is an immune signature for lymphocyte activation in hemophagocytic lymphohistiocytosis, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (fig 2). Front Immunol (2013) ncbi |
| mouse monoclonal (GB11) |
| In order to study the pulmonary immune response to Francisella tularensis, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 2). Microbes Infect (2013) ncbi |
| mouse monoclonal (GB11) |
| In order to examine how NK cells integrate signals induced by stress and antibody-coated cells, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples (fig 2). J Immunol (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to study T cell responses elicited by Ad5 and those of alternative-serotype Ad vectors, Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on mouse samples . J Virol (2013) ncbi |
| mouse monoclonal (GB12) |
| In order to study the use of an IL-12 adjuvant when vaccinating rhesus macaques, Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on rhesus macaque samples (fig 4). Hum Vaccin Immunother (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to study the role of IL-15 and IL-7 on CD8 T cells during infection with Toxoplasma gondii, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 3). Microbes Infect (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to study TLR7 knockout mice infected with lymphocytic choriomeningitis virus, Invitrogen granzyme B antibody (Invitrogen, MHGB04) was used in flow cytometry on mouse samples at 1:50 (fig 2). Cell Host Microbe (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to study CD8(+) T cell homeostasis and CD8-mediated autoimmunity, Invitrogen granzyme B antibody (Invitrogen, clone GB11) was used in flow cytometry on mouse samples (fig 4). J Immunol (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate how TGF-beta signaling regulates the self-reactivity of peripheral T cells, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples . Nat Immunol (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to identify a new population of CD8(+)FoxP3(+) T(reg), Invitrogen granzyme B antibody (Invitrogen, MHGB05) was used in flow cytometry on mouse samples . Blood (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to study HIV-specific CD8 T cells, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on human samples (fig 5). Blood (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to optimize a DNA vaccine to boost cellular immune responses induced by Ad5 prime, Invitrogen granzyme B antibody (Invitrogen, GRB11) was used in flow cytometry on rhesus macaque samples (fig 4a). Vaccine (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to study the contribution of IL-10 in mice infected with respiratory syncytial virus, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples . PLoS ONE (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate immune mechanisms that facilitate viral clearance and contribute to persistent lung inflammation following SARS-CoV infection, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on African green monkey samples (fig 6). J Virol (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to report the effect of T regulatory cell depletion during acute respiratory syncytial virus infection, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples . Mucosal Immunol (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to determine the role of granzyme B in immune regulation during viral infections, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 2). J Immunol (2011) ncbi |
| rat monoclonal (16G6) |
| In order to report coreceptor gene imprinting as a critical determinant of lineage fate determination in the thymus, Invitrogen granzyme B antibody (eBioscience, 16G6) was used in flow cytometry on mouse samples . EMBO J (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to determine the role for DOCK8 in peripheral CD8 T cell survival and function, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on human samples . J Exp Med (2011) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize different macaque NK cell subpopulations, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on rhesus macaque samples (fig 2). Immunology (2011) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate the role of TRAIL in the pulmonary CD8 T cell response to influenza A virus, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 3). J Immunol (2011) ncbi |
| mouse monoclonal (GB12) |
| In order to examine the HA-specific T-cell responses among a cohort of young and elderly influenza vaccines, Invitrogen granzyme B antibody (Caltag, clone GB12) was used in flow cytometry on human samples (fig 3). Vaccine (2011) ncbi |
| mouse monoclonal (GB12) |
| In order to elucidate the protective role of CD8(+) T cells against Histoplasma capsulatum, Invitrogen granzyme B antibody (Caltag, MHGB04) was used in flow cytometry on mouse samples (fig 1). Infect Immun (2011) ncbi |
| mouse monoclonal (GZB01) |
| In order to study subcutaneous panniculitis-like T-cell lymphomas in Korean patients, Invitrogen granzyme B antibody (NeoMarkers, GZB01) was used in immunohistochemistry on human samples (fig 3). Ann Dermatol (2011) ncbi |
| mouse monoclonal (GB12) |
| In order to examine red blood cells as an immunogen, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 3). Am J Transplant (2011) ncbi |
| mouse monoclonal (GB11) |
| In order to suggest that PD-1 expression during acute infection is not a marker of T cell exhaustion, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 4). J Immunol (2011) ncbi |
| mouse monoclonal (GZB01) |
| In order to examine tumor and nonadjacent normal breast tissue from women with breast cancer, who either had or had not received neoadjuvant chemotherapy before surgery, Invitrogen granzyme B antibody (Thermo Scientific, MS-1157-S1) was used in immunohistochemistry on human samples at 1:50 (fig 5I). Proc Natl Acad Sci U S A (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to study the effects of type I-interferon on graft verses host disease, Invitrogen granzyme B antibody (Invitrogen, MHGB05) was used in flow cytometry on mouse samples (fig 5). Blood (2011) ncbi |
| mouse monoclonal (GB12) |
| In order to examine the effect of n-3 PUFA-docosahexaenoic acid bladder and pancreatic cancer cells, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (fig 2). J Nutr Biochem (2012) ncbi |
| mouse monoclonal (GB12) |
| In order to examine the impact of neutrophils on CD8 positive T-cell responses during influenza virus infection, Invitrogen granzyme B antibody (Caltag, MHGB05) was used in flow cytometry on mouse samples (fig 6). Immunol Cell Biol (2012) ncbi |
| mouse monoclonal (GB11) |
| In order to study the contribution of the cellular immune response in maintaining nonpathogenic SIV infection in sooty mangabeys, Invitrogen granzyme B antibody (Invitrogen, clone GB11-PETxRed) was used in flow cytometry on human samples (fig 3). J Immunol (2011) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the role of CD8 T cells to the brain and liver damage observed during infection with Plasmodium berghei ANKA, Invitrogen granzyme B antibody (Caltag Laboratories, GB12) was used in flow cytometry on mouse samples (fig 2). Infect Immun (2011) ncbi |
| mouse monoclonal (GB12) |
| In order to examine the IRF4-Blimp1-Bcl6 regulatory axis in NK development, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 4). Blood (2011) ncbi |
| mouse monoclonal (GB12) |
| In order to report that NAD(+) regulates the survival, phenotype, and function of T regulatory cells via the ART2-P2X7 pathway, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 5, 6). J Exp Med (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to test if selective depletion of Foxp3(+) Tregs reduces cancer, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig 4). Cancer Res (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate immune mechanisms responsible for viral control in Indian rhesus macaques infected SIV, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on rhesus macaque samples (fig 6). J Immunol (2010) ncbi |
| rat monoclonal (16G6) |
| In order to report sex-dependent, B7-H1-dependent differences in tumor immunity, Invitrogen granzyme B antibody (eBioscience, 16G6) was used in flow cytometry on mouse samples (fig 2, 3). J Immunol (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the function of the Vaccinia virus A47L gene, Invitrogen granzyme B antibody (Invitrogen, clone GB12) was used in flow cytometry on human samples (fig 6). J Virol (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to identify immunologic correlates of immune reconstitution inflammatory syndrome in HIV patients, Invitrogen granzyme B antibody (Caltag, clone GB12) was used in flow cytometry on human samples (fig 3). Blood (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to characterize natural killer T subsets in sooty mangabey, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on African green monkey samples (fig 5). J Med Primatol (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to study Vgamma2Vdelta2 T cells from Caucasian or African American donors, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (fig 4). Hum Immunol (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the different immune responses when mice are infected with type I or type II strains of T. gondii, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on mouse samples (fig s2). J Immunol (2010) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate how bystander CD8 cells are impacted during viral infection, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on mouse samples (fig 2). J Immunol (2010) ncbi |
| mouse monoclonal (GB11) |
| In order to use a transgenic mouse model of spontaneous astrocytoma to study immune infiltrate, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples (fig 6). Cancer Res (2010) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate changes to macaque NK-cell subsets during infection with SIV, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on rhesus macaque samples (fig 5). Blood (2010) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate the effect of perforin on specific endocytosis process, Invitrogen granzyme B antibody (Caltag Laboratories, GB11) was used in immunocytochemistry on human samples . Blood (2010) ncbi |
| rat monoclonal (16G6) |
| In order to assess the consequences of phosphoinositide (3,4,5)-triphosphate binding to 3-phosphoinositide-dependent kinase 1, Invitrogen granzyme B antibody (eBioscience, 16G6) was used in flow cytometry on mouse samples (fig 2e). Mol Cell Biol (2009) ncbi |
| mouse monoclonal (GB12) |
| In order to study the influence of Treg on pathogen-specific CD8+ T-cell responses in vivo, Invitrogen granzyme B antibody (Caltag Laboratories, GB12) was used in flow cytometry on mouse samples . Blood (2009) ncbi |
| mouse monoclonal (GB12) |
| In order to identify conditions in which granzyme B is produced by human B cells, Invitrogen granzyme B antibody (Invitrogen, GB12) was used in flow cytometry on human samples (fig 1). J Immunol (2009) ncbi |
| mouse monoclonal (GB12) |
| In order to examine granzyme expression during influenza infection, Invitrogen granzyme B antibody (Caltag, MHGB05) was used in flow cytometry on mouse samples . Eur J Immunol (2009) ncbi |
| mouse monoclonal (GB11) |
| In order to explore how naive CD4 cells differentiate into class II restricted killers, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples (fig 1). Cell Immunol (2009) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize peripheral natural killer cells in patients with rheumatoid arthritis, Invitrogen granzyme B antibody (Caltag Laboratories, GRB04) was used in flow cytometry on human samples . Mod Rheumatol (2009) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate the role of IL-17 in influenza A infection, Invitrogen granzyme B antibody (Caltag Laboratories, GB11) was used in flow cytometry on mouse samples (fig 5b). J Immunol (2009) ncbi |
| mouse monoclonal (GB12) |
| In order to study the role of the transcription regulator CCCTC-binding factor in Th2 differentiation, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples . J Immunol (2009) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate the role of interleukin-15 in human natural killer cell development, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on human samples . J Exp Med (2009) ncbi |
| mouse monoclonal (GB11) |
| In order to determine the importance of TRAIL to influenza-specific CD8(+) T cell immunity and control of the infection, Invitrogen granzyme B antibody (Invitrogen, GB11) was used in flow cytometry on human samples (fig 5). J Immunol (2008) ncbi |
| mouse monoclonal (GB12) |
| In order to measure effector gene expression early after CTL activation, Invitrogen granzyme B antibody (Caltag Laboratories, GB12) was used in flow cytometry on mouse samples . J Immunol (2008) ncbi |
| mouse monoclonal (GB12) |
| In order to characterize Tregs from older subjects and mice, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (tbl 1). J Immunol (2008) ncbi |
| mouse monoclonal (GB12) |
| In order to study Vgamma2Vdelta2 T cells in HIV infected patients, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (fig 1). J Leukoc Biol (2008) ncbi |
| mouse monoclonal (GB12) |
| In order to test the efficacy of DNA vaccination with anaplastic lymphoma kinase in a mouse model of anaplastic large cell lymphoma, Invitrogen granzyme B antibody (Caltag, GB12) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1). Nat Med (2008) ncbi |
| mouse monoclonal (GB12) |
| In order to analyze protection against Plasmodium berghei by a single-dose simian adenovirus vector using a human cytomegalovirus promoter containing intron A, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples . J Virol (2008) ncbi |
| rat monoclonal (16G6) |
| In order to study how multifactorial adjuvants show reduced toxicity and enhanced efficacy compared to unitary adjuvants as cancer vaccines, Invitrogen granzyme B antibody (eBioscience, 16G6) was used in flow cytometry on mouse samples (fig 4). Blood (2008) ncbi |
| rat monoclonal (16G6) |
| Invitrogen granzyme B antibody (eBioscience, 16G6) was used in flow cytometry on mouse samples . Nat Immunol (2008) ncbi |
| mouse monoclonal (GB12) |
| In order to test if granzyme B is produced in the myeloid cell lines HL-60 and U937, in CD34+ stem cells, and in PMN derived from CD34+ cells in vitro, Invitrogen granzyme B antibody (Caltag, Invitrogen,, GB12) was used in flow cytometry on human samples . Mol Immunol (2008) ncbi |
| mouse monoclonal (GB12) |
| In order to assess the contributions of viral replication levels in the induction and activation of cytotoxic T cells, Invitrogen granzyme B antibody (Caltag Laboratories, GB12) was used in flow cytometry on mouse samples . J Virol (2007) ncbi |
| mouse monoclonal (GB12) |
| In order to examine rhesus cytomegalovirus-specific CD8+ T lymphocytes, Invitrogen granzyme B antibody (Caltag, clone GB12) was used in flow cytometry on human samples (fig 1). J Immunol Methods (2007) ncbi |
| mouse monoclonal (GB11) |
| In order to determine if clonal expansion and acquisition of effector functions driven by antigen presenting cells is reshaped during the effector phase to adapt to the effector site microenvironment in murine brain tumor models, Invitrogen granzyme B antibody (Invitrogen/ Life Technologies, GB11) was used in flow cytometry on mouse samples (fig 3B) and in flow cytometry on human samples (fig 5C). J Immunol (2007) ncbi |
| mouse monoclonal (GB12) |
| In order to explore how naive, effector, and memory T cells differ in cytotoxic potential, Invitrogen granzyme B antibody (Caltag Laboratories, GB12) was used in flow cytometry on mouse samples (fig 5). J Immunol (2007) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate CTLA-4 regulation of cytotoxic T lymphocytes in a transgenic model of CD8+ T-cell-mediated myocarditis, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples (fig 7). Circ Res (2007) ncbi |
| mouse monoclonal (GB12) |
| In order to elucidate the developmental relationship between natural killer subsets, Invitrogen granzyme B antibody (Caltag Laboratories, GB12) was used in flow cytometry on human samples (fig 3). J Immunol (2007) ncbi |
| mouse monoclonal (GB11) |
| In order to report that NKT cells produce IL-21 and that IL-21 regulates NKT function, Invitrogen granzyme B antibody (Caltag Laboratories, GB11) was used in flow cytometry on mouse samples (fig 2). J Immunol (2007) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the role of JNK2 in CD8+ T cell response and effector functions, Invitrogen granzyme B antibody (CALTAG, MHGB04) was used in flow cytometry on mouse samples (fig 4). Eur J Immunol (2007) ncbi |
| mouse monoclonal (GB12) |
| In order to study CD4(+) CD25 (+) regulatory T cells in B-cell non-Hodgkin's lymphoma and attenuation of CD8(+) T-cell function, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples at 1:200 (fig 3A). Cancer Res (2006) ncbi |
| mouse monoclonal (GB11) |
| In order to study CD8+ T cell responses during herpesvirus infection, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples . J Virol (2006) ncbi |
| mouse monoclonal (GB12) |
| In order to determine the frequency, phenotype, and function of peripheral CD4+ CD8+ T cells in rhesus macaques infected with simian immunodeficiency virus, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on rhesus macaque samples . Immunology (2006) ncbi |
| mouse monoclonal (GB12) |
| In order to test if perforin polymorphisms influence the progression of HIV infection, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (fig 2). Int J Immunogenet (2006) ncbi |
| mouse monoclonal (GB12) |
| In order to study interaction between CD4+CD25+ T cells and B cells, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples (fig 4). Blood (2006) ncbi |
| mouse monoclonal (GB11) |
| In order to study the effects of prolonged antigen exposure, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples (fig 6). J Immunol (2006) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the role of T-bet in Valpha14i natural killer T cell function, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples (fig 3). Blood (2006) ncbi |
| mouse monoclonal (GB12) |
| In order to review characteristics of non-T, non-B cell CD4+CD56+ neoplasms with lymphoblastic morphology, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (tbl 1). Eur J Haematol (2005) ncbi |
| mouse monoclonal (GB12) |
| In order to evaluate the use of a bispecific antibody to treat human Ep-CAM-overexpressing carcinomas, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (fig 5). Mol Immunol (2006) ncbi |
| mouse monoclonal (GB12) |
| In order to evaluate the tuberculosis vaccine candidate Mtb72F, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples . Infect Immun (2005) ncbi |
| mouse monoclonal (GB12) |
| In order to use flow cytometry to study granzyme A, B, and K expression in human peripheral blood lymphocytes, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (tbl 2). Eur J Immunol (2005) ncbi |
| mouse monoclonal (GB12) |
| In order to examine impairment of cytotoxic CD8+ T-cell effector function during chronic Friend virus infection, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples (fig 5B). J Virol (2005) ncbi |
| mouse monoclonal (GB11) |
| In order to evaluate the therapeutic potential of different tumor-reactive CD8+ T cell memory subsets in vivo, Invitrogen granzyme B antibody (Caltag, GB11) was used in flow cytometry on mouse samples (fig 2). Proc Natl Acad Sci U S A (2005) ncbi |
| mouse monoclonal (GB12) |
| In order to analyze triplets infected with HHV-8 and the development of hemophagocytic lymphohistiocytosis, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples . Blood (2005) ncbi |
| mouse monoclonal (GB12) |
| In order to analyze ocular herpes simplex virus-1 infection and the migration and development of protective CD8+ T cells into the nervous system, Invitrogen granzyme B antibody (Caltag Laboratories, GB12) was used in flow cytometry on mouse samples (fig 5). J Immunol (2005) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the role of granzyme B in T regulatory cell-mediated suppression, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples at 1:200 (fig 1). J Immunol (2005) ncbi |
| mouse monoclonal (GB12) |
| In order to assess the impact of nucleotide synthesis inhibition on CD8 T cell differentiation, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples (fig 3A). J Immunol (2004) ncbi |
| mouse monoclonal (GB12) |
| In order to report that human neutrophils lack granzyme A, granzyme B, and perforin, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples (fig 1). Blood (2004) ncbi |
| mouse monoclonal (GB12) |
| In order to study granzymes A and B and differential expression in human cytotoxic lymphocyte subsets and T regulatory cells, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples at 1:400 and in flow cytometry on mouse samples at 1:400. Blood (2004) ncbi |
| mouse monoclonal (GB12) |
| In order to investigate the role of cytotoxic effector-memory CD8(+) T cell during persistent viral infection, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on mouse samples (fig 1). J Immunol (2003) ncbi |
| mouse monoclonal (GB12) |
| In order to assess genetic variation in granzyme B, Invitrogen granzyme B antibody (Caltag, GB12) was used in flow cytometry on human samples at 10 ug/ml. Proc Natl Acad Sci U S A (2003) ncbi |
| mouse monoclonal (GrB-7) |
| In order to measure granzyme A and B expression in non-pathological lymphoid tissue and peripheral blood lymphocyte subpopulations, Invitrogen granzyme B antibody (noco, GrB-7) was used in immunohistochemistry - paraffin section on human samples . Clin Exp Immunol (1995) ncbi |
BioLegend
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372206) was used in flow cytometry on mouse samples at 1:25. Nat Commun (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples (fig 6d, s4a). Front Cell Infect Microbiol (2022) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolgend, 372206) was used in flow cytometry on mouse samples at 1:50 (fig 6h). Nat Commun (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples (fig 3f). Theranostics (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515408) was used in flow cytometry on mouse samples (fig s1a, s4f). Sci Adv (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples (fig 3f). Oncoimmunology (2022) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, QA16A02) was used in flow cytometry on mouse samples (fig s6d). Nat Commun (2022) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372213) was used in flow cytometry on mouse samples at 1:50 (fig 6i, s8). Nat Commun (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515403) was used in flow cytometry on mouse samples (fig 2m). J Immunother Cancer (2022) ncbi |
| rat recombinant (QA18A28) |
| BioLegend granzyme B antibody (BioLegend, 396412) was used in flow cytometry on mouse samples (fig 1e, s2e). J Immunother Cancer (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515403) was used in flow cytometry on mouse samples at 1:50 (fig 4c). J Biol Chem (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig s10). Oncoimmunology (2022) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515408) was used in flow cytometry on mouse samples at 1:100 (fig 3f, 3g, s7c). Nat Nanotechnol (2022) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372203) was used in flow cytometry on mouse samples at 1:100 (fig 4f, 4g). Nat Nanotechnol (2022) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (BioLegend, QA16A02) was used in flow cytometry on mouse samples at 1:100 (fig 1d). J Immunother Cancer (2021) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on mouse samples (fig 5b). Commun Biol (2021) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515408) was used in flow cytometry on mouse samples (fig s4c). J Immunother Cancer (2021) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372213) was used in flow cytometry on mouse samples (fig s3b). J Immunother Cancer (2021) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515405) was used in flow cytometry on mouse samples at 1:100 (fig s4b). iScience (2021) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (BioLegend, 372204) was used in flow cytometry on mouse samples at 1:100 (fig 4e). Nat Commun (2021) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372208) was used in flow cytometry on mouse samples (fig s4c). JCI Insight (2021) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515405) was used in flow cytometry on mouse samples at 1:200 (fig 3d). Proc Natl Acad Sci U S A (2021) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (BioLegend, QA16A02) was used in flow cytometry on mouse samples at 1:50 (fig s16a). Sci Transl Med (2021) ncbi |
| rat recombinant (QA18A28) |
| BioLegend granzyme B antibody (BioLegend, 396413) was used in flow cytometry on mouse samples (fig 8a). Neoplasia (2021) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372204) was used in flow cytometry on human samples (fig 2f) and in flow cytometry on mouse samples (fig 6f). Sci Rep (2021) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515406) was used in flow cytometry on human samples (fig 3e). Cell (2020) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515408) was used in flow cytometry on mouse samples at 1:100 (fig ev2c). EMBO Mol Med (2020) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples (fig 5f, 5g). Science (2020) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515406) was used in flow cytometry on mouse samples at 1:100 (fig 8d). Nat Commun (2020) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, QA16A02) was used in flow cytometry on mouse samples (fig 3h). Nature (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on mouse samples (fig 2d, 2l). Science (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515407) was used in flow cytometry on mouse samples (fig s5a). Cell (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515403) was used in flow cytometry on human samples (fig 10b). Cell Mol Gastroenterol Hepatol (2020) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372208) was used in flow cytometry on mouse samples (fig 5c). Cell (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515403) was used in flow cytometry on mouse samples at 1:50 (fig 4c, 6j). Nat Commun (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig 3a). J Immunol (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig 2a). J Immunol (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515403) was used in flow cytometry on mouse samples at 1:100 (fig s2b). Nat Commun (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on human samples at 1:100 (fig 3h). elife (2019) ncbi |
| mouse monoclonal (M3304B06) |
| BioLegend granzyme B antibody (Biolegend, M3304B06) was used in western blot on human samples at 1:500 (fig 3s1b). elife (2019) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on mouse samples (fig 3a). Front Immunol (2018) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on human samples (fig s1d). Proc Natl Acad Sci U S A (2018) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515403) was used in flow cytometry on mouse samples (fig 3f). Cell Rep (2018) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (Biolegend, 372204) was used in flow cytometry on mouse samples (fig 3m). Cancer Res (2018) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig s6a). Sci Immunol (2018) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (BioLegend, QA16A02) was used in flow cytometry on mouse samples (fig 5c). Cell Immunol (2018) ncbi |
| mouse recombinant (QA16A02) |
| BioLegend granzyme B antibody (BioLegend, QA16A02) was used in flow cytometry on human samples (fig 6c). Int J Infect Dis (2018) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515408) was used in flow cytometry on mouse samples (fig s2b). Cell (2018) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, 515403) was used in flow cytometry on mouse samples (fig s10g). Nature (2018) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, 515403) was used in flow cytometry on mouse samples at 1:200 (fig 8b). Nat Cell Biol (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to evaluate mouse models of hepacivirus infection, BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples . Science (2017) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig 4c). Oncotarget (2017) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig 6a). J Exp Med (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to demonstrate that neonatal CD8 positive T cells have a specific genetic program biased toward the innate immune response, BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on human samples (fig s6d). Cell Rep (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to functionally characterize herpes simplex virus-specific CD8 positive T cells, BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig 4a). J Virol (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate the role of Eomes in the retention of liver natural killer cells, BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig 1e). J Immunol (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to test how inhibiting autophagy impacts antitumor immune responses in immune-competent mouse models of melanoma and mammary cancer, BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on mouse samples at 1:400 (fig 3a). J Clin Invest (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to study T cell migration in inflammatory demyelinating lesions confined to optic nerves and spinal cord, BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on mouse samples (fig 3b). Proc Natl Acad Sci U S A (2016) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on human samples (fig 5). PLoS Pathog (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to identify and characterize follicular cytotoxic T cells, BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples at 1:200 (tbl s2). Nat Immunol (2016) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on human samples (fig 1). J Immunol (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize innate lymphoid cell subpopulations isolated from patients with systemic sclerosis, BioLegend granzyme B antibody (biolegend, GB11) was used in flow cytometry on human samples (fig s1). J Immunol (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to assess arming of MAIT cell cytolytic antimicrobial activity and induction by IL-7 and faulty in HIV-1 infection, BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on human samples (fig 1). PLoS Pathog (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate the role of VAMP8 in exocytosis, BioLegend granzyme B antibody (BioLegend, GB11) was used in immunocytochemistry on human samples (fig 2). J Cell Biol (2015) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on mouse samples (fig 1). J Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to report that AMPK regulates protein phosphatase activity to control the of survival and function of CD8+ T cells, thus regulating immune surveillance of tumors, BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples . Oncotarget (2015) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (Biolegend, GB11) was used in flow cytometry on mouse samples (fig 7) and in flow cytometry on human samples (fig 4). J Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples (fig 4). J Virol (2015) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on human samples at 5,000 ug/ml (fig 3). J Surg Res (2015) ncbi |
| mouse monoclonal (GB11) |
| BioLegend granzyme B antibody (BioLegend, GB11) was used in flow cytometry on mouse samples (fig 6). Am J Pathol (2014) ncbi |
| mouse monoclonal (GB11) | BioLegend granzyme B antibody (BioLegend, 515403) was used . Cancer Res (2014) ncbi |
Abcam
| mouse monoclonal (GZMB/2403) |
| Abcam granzyme B antibody (Abcam, ab237847) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig s16c) and in immunohistochemistry - paraffin section on human samples at 1:100 (fig s1e). Sci Transl Med (2021) ncbi |
| domestic rabbit monoclonal (EPR8260) |
| Abcam granzyme B antibody (Abcam, ab134933) was used in immunohistochemistry on human samples at 1:300 (fig 2b). Cancer Immunol Immunother (2020) ncbi |
| domestic rabbit monoclonal (EPR8260) |
| In order to investigate the tumor microenvironment in tertiary lymphoid organs of prostate cancer patients, Abcam granzyme B antibody (Abcam, EPR8260) was used in immunohistochemistry on human samples (fig 9a). Front Immunol (2017) ncbi |
Santa Cruz Biotechnology
| mouse monoclonal (2C5) |
| Santa Cruz Biotechnology granzyme B antibody (Santa Cruz Biotechnology, sc-8022) was used in western blot on mouse samples at 1:1000 (fig 8g). Nat Commun (2022) ncbi |
| mouse monoclonal (2C5) |
| In order to learn the possible role of incipient renal fibrosis by variable expression of neural cell adhesion molecule isoforms in renal tissue, Santa Cruz Biotechnology granzyme B antibody (Santa Cruz Biotechnology, sc-8022) was used in immunohistochemistry - frozen section on human samples at 1:50 (fig 2). PLoS ONE (2015) ncbi |
Bio-Rad
| mouse monoclonal (GB11) |
| In order to study NK function in solid tumors, Bio-Rad granzyme B antibody (AbD Serotec, GB11) was used in flow cytometry on human samples . Int J Cancer (2014) ncbi |
Dako
| mouse monoclonal (GrB-7) |
| In order to characterize cases of recurrent panniculitis in children with lipoatrophy, Dako granzyme B antibody (DAKO, GRB-7) was used in immunohistochemistry - paraffin section on human samples (tbl 3). J Eur Acad Dermatol Venereol (2017) ncbi |
| mouse monoclonal (GrB-7) |
| Dako granzyme B antibody (Dako, GrB-7) was used in immunohistochemistry - paraffin section on human samples (fig 5f). J Immunol (2016) ncbi |
| mouse monoclonal (GrB-7) |
| In order to utilize humanized major histocompatibility class I- and class II-deficient NOG mice to assess the antitumor effect of an anti-programmed death-1 antibody, Dako granzyme B antibody (DAKO, GrB-7) was used in immunohistochemistry on mouse samples (fig 6a). Clin Cancer Res (2017) ncbi |
| mouse monoclonal (GrB-7) |
| In order to describe the gluteal lesions of a patient with pagetoid reticulosis, Dako granzyme B antibody (Dako, GrB7) was used in immunohistochemistry on human samples at 1:10. J Cutan Pathol (2015) ncbi |
| mouse monoclonal (GrB-7) |
| Dako granzyme B antibody (Dako, GrB-7) was used in immunohistochemistry - paraffin section on human samples . J Cutan Pathol (2015) ncbi |
| mouse monoclonal (GrB-7) |
| Dako granzyme B antibody (Dako, GrB-7) was used in immunohistochemistry on human samples at 1:40. J Cutan Pathol (2015) ncbi |
Cell Signaling Technology
| domestic rabbit polyclonal |
| Cell Signaling Technology granzyme B antibody (Cell Signaling Technology, 4275) was used in flow cytometry on mouse samples . EMBO Mol Med (2021) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology granzyme B antibody (Cell Signaling Technology, 4275) was used in western blot on mouse samples at 1:2000 (fig 3d). Nat Commun (2019) ncbi |
| domestic rabbit monoclonal (D6E9W) |
| Cell Signaling Technology granzyme B antibody (Cell Signaling, D6E9W) was used in immunohistochemistry on mouse samples (fig 2v). J Immunol (2019) ncbi |
| domestic rabbit polyclonal |
| Cell Signaling Technology granzyme B antibody (Cell Signaling, 4275) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi |
| domestic rabbit polyclonal |
| In order to quantify changes in cytoplasmic and mitochondrial interactomes in response to apoptosis initiation as a function of caspase activity, Cell Signaling Technology granzyme B antibody (Cell Signaling, 4275) was used in western blot on human samples (fig s11a). Mol Syst Biol (2017) ncbi |
BD Biosciences
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD, 560211) was used in flow cytometry on human samples (fig 3i). Nat Commun (2022) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD, 560212) was used in flow cytometry on mouse samples (fig 4c) and in flow cytometry on human samples (fig 2c). Sci Adv (2022) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples at 1:100 (fig s1c). Nature (2021) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, 560212) was used in flow cytometry on human samples (fig 7a-7b). elife (2020) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, 560211) was used in flow cytometry on human samples (fig 14a). Hum Vaccin Immunother (2020) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, 562462) was used in flow cytometry on mouse samples (fig 3a, 6g). Cell Rep (2019) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Pharmingen, 561142) was used in flow cytometry on human samples (fig 6c). Sci Rep (2019) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, 560213) was used in flow cytometry on mouse samples (fig s6g). Cell (2019) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 1b). Eur J Immunol (2019) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, 560213) was used in flow cytometry on human samples (fig 2d). Cell Rep (2018) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig s3a). Proc Natl Acad Sci U S A (2018) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD, GB11) was used in flow cytometry on human samples (fig s6). J Clin Invest (2018) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 3d). Clin Exp Immunol (2018) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, 561142) was used in flow cytometry on African green monkey samples (fig s5a). J Clin Invest (2018) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 2g). J Clin Invest (2018) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on mouse samples (fig 2b). J Immunol (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize fetal natural killer cells, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 3b). JCI Insight (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to show T cell immunoglobulin and ITIM domain expression increases over time despite early initiation of antiretroviral treatment, BD Biosciences granzyme B antibody (BD Bioscience, GB11) was used in flow cytometry on human samples (fig 5c). Sci Rep (2017) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the kinetics of SIV-specific CD8+ T cell cytolytic factor expression in peripheral blood, lymph node, spleen, and gut mucosa from early acute infection through chronic infection, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on rhesus macaque samples (fig 2b). PLoS Pathog (2016) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on mouse samples (fig 5a). Cell (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize gammadelta T cell subsets from healthy humans, BD Biosciences granzyme B antibody (BD, GB11) was used in flow cytometry on human samples (fig 1e). Proc Natl Acad Sci U S A (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to characterize CD8 positive alpha beta gamma delta T cells, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 3a). J Immunol (2016) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig s4b). Proc Natl Acad Sci U S A (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to assess receptor for hyaluronic acid-mediated motility specific dendritic cell responses, BD Biosciences granzyme B antibody (BD Biosciences, 560211) was used in flow cytometry on human samples (fig 3). Oncotarget (2016) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 2a). Sci Rep (2016) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (Becton-Dickinson, GB11) was used in flow cytometry on human samples (fig s1). J Immunol (2016) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, 561998) was used in flow cytometry on human samples (fig 3). Oncoimmunology (2016) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Pharmigen, 560212) was used in flow cytometry on human samples (fig 1). Oncoimmunology (2016) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD, GB11) was used in flow cytometry on human samples (fig 3e). J Clin Invest (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to discuss the use of flow cytometry to examine common marmosets, BD Biosciences granzyme B antibody (BD, GB11) was used in flow cytometry on African green monkey samples (fig 1g). J Med Primatol (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to study chronic hepatitis C virus infections and the functional dichotomy of V-delta2 gamma-delta T cells and their role in cytotoxicity and not IFN-gamma production, BD Biosciences granzyme B antibody (BD PharMingen, GB11) was used in flow cytometry on human samples (fig 3). Sci Rep (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to assess the impact of neoantigen intratumor heterogeneity on antitumor immunity, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 3c). Science (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to elucidate mechanisms that regulate T cell glycolytic metabolism, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 1). Nat Immunol (2016) ncbi |
| mouse monoclonal (GB11) |
| In order to study the use of bispecific T cell engager, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig s7). PLoS ONE (2015) ncbi |
| mouse monoclonal (2C5/F5) |
| In order to investigate the role of TIGIT in the immune response, BD Biosciences granzyme B antibody (BD Pharmingen, 2C5/F5) was used in flow cytometry on mouse samples (fig 4c). J Clin Invest (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to assess arming of MAIT cell cytolytic antimicrobial activity and induction by IL-7 and faulty in HIV-1 infection, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 1). PLoS Pathog (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the effects of immunosuppressive agents on Polyomavirus BKV-specific T cells, BD Biosciences granzyme B antibody (BD Bioscience, GB11) was used in flow cytometry on human samples (fig 1a). Kidney Int (2015) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD, GB11) was used in flow cytometry on human samples . J Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the phenotype and function of peripheral gammadelta T cells in patients with chronic hepatitis B during pegylated-interferon-alpha treatment, BD Biosciences granzyme B antibody (BD, GB11) was used in flow cytometry on human samples . PLoS ONE (2015) ncbi |
| mouse monoclonal (2C5/F5) |
| BD Biosciences granzyme B antibody (BD Biosciences, 2C5/F5) was used in western blot on human samples . Mol Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the early impact of viral replicative capacity on HIV-1 immunopathogenesis, BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (tbl s2). Proc Natl Acad Sci U S A (2015) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Biosciences, GB11) was used in flow cytometry on human samples (fig 3). J Immunol (2015) ncbi |
| mouse monoclonal (GB11) |
| In order to investigate when Vgamma9Vdelta2 T cells develop, BD Biosciences granzyme B antibody (BD Bioscience, GB11) was used in flow cytometry on human samples (tbl s5). Proc Natl Acad Sci U S A (2015) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD, GB11) was used in flow cytometry on human samples . Clin Cancer Res (2014) ncbi |
| mouse monoclonal (GB11) |
| In order to examine the effect of lytic EBV antigen-specific CD8+ T cells on EBV infection in humanized mice, BD Biosciences granzyme B antibody (BD Pharmigen, GB11) was used in flow cytometry on human samples . PLoS Pathog (2014) ncbi |
| mouse monoclonal (GB11) |
| BD Biosciences granzyme B antibody (BD Bioscience, GB11) was used in flow cytometry on human samples . Med Microbiol Immunol (2014) ncbi |
Leica Biosystems
| monoclonal (11F1) |
| Leica Biosystems granzyme B antibody (Novocastra, 11F1) was used in immunohistochemistry on human samples at 1:100. Ann Hematol (2021) ncbi |
| monoclonal (11F1) |
| Leica Biosystems granzyme B antibody (Leica, PA0299) was used in immunohistochemistry - paraffin section on human samples (fig 1a). Cancer Res (2021) ncbi |
| mouse monoclonal (11F1) |
| Leica Biosystems granzyme B antibody (Novocastra, NCL-Gran-B) was used in immunohistochemistry - paraffin section on human samples at 1:20 (fig s3). Oncoimmunology (2017) ncbi |
| monoclonal (11F1) |
| Leica Biosystems granzyme B antibody (Leica Biosysytems, PA0299) was used in immunohistochemistry on human samples (fig 3a). PLoS ONE (2017) ncbi |
Articles Reviewed
- Hou X, Shi Y, Kang X, Rousu Z, Li D, Wang M, et al. Echinococcus granulosus: The establishment of the metacestode in the liver is associated with control of the CD4+ T-cell-mediated immune response in patients with cystic echinococcosis and a mouse model. Front Cell Infect Microbiol. 2022;12:983119 pubmed publisher
- Ryan P, Sumaria N, Holland C, Bradford C, Izotova N, Grandjean C, et al. Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals. Proc Natl Acad Sci U S A. 2016;113:14378-14383 pubmed
- Kadivar M, Petersson J, Svensson L, Marsal J. CD8??+ ?? T Cells: A Novel T Cell Subset with a Potential Role in Inflammatory Bowel Disease. J Immunol. 2016;197:4584-4592 pubmed
- Srivastava R, Khan A, Garg S, Syed S, Furness J, Vahed H, et al. Human Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against Ocula. J Virol. 2017;91: pubmed publisher
- Cuff A, Robertson F, Stegmann K, Pallett L, Maini M, Davidson B, et al. Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation. J Immunol. 2016;197:4283-4291 pubmed
- Peters C, Häsler R, Wesch D, Kabelitz D. Human Vδ2 T cells are a major source of interleukin-9. Proc Natl Acad Sci U S A. 2016;113:12520-12525 pubmed
- Hu X, Valentin A, Dayton F, Kulkarni V, Alicea C, Rosati M, et al. DNA Prime-Boost Vaccine Regimen To Increase Breadth, Magnitude, and Cytotoxicity of the Cellular Immune Responses to Subdominant Gag Epitopes of Simian Immunodeficiency Virus and HIV. J Immunol. 2016;197:3999-4013 pubmed
- Chandele A, Sewatanon J, Gunisetty S, Singla M, Onlamoon N, Akondy R, et al. Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India. J Virol. 2016;90:11259-11278 pubmed
- Klotz L, Kuzmanov I, Hucke S, Gross C, Posevitz V, Dreykluft A, et al. B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6182-E6191 pubmed
- Liechtenstein T, Perez Janices N, Blanco Luquin I, Goyvaerts C, Schwarze J, Dufait I, et al. Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy. Oncoimmunology. 2014;3:e945378 pubmed
- Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
- Bhela S, Kempsell C, Manohar M, Dominguez Villar M, Griffin R, Bhatt P, et al. Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR-CD25hiCD127lo Tregs in multiple sclerosis and in response to IL-6. J Immunol. 2015;194:2180-9 pubmed publisher
- Srivastava R, Khan A, Spencer D, Vahed H, Lopes P, Thai N, et al. HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgenic. J Immunol. 2015;194:2232-48 pubmed publisher
- Khan A, Srivastava R, Spencer D, Garg S, Fremgen D, Vahed H, et al. Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpes. J Virol. 2015;89:3776-92 pubmed publisher
- Teixeira C, Gomes R, Oliveira F, Meneses C, Gilmore D, Elnaiem D, et al. Characterization of the early inflammatory infiltrate at the feeding site of infected sand flies in mice protected from vector-transmitted Leishmania major by exposure to uninfected bites. PLoS Negl Trop Dis. 2014;8:e2781 pubmed publisher
- Meythaler M, Wang Z, Martinot A, Pryputniewicz S, Kasheta M, McClure H, et al. Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection. J Immunol. 2011;186:5151-61 pubmed publisher
- von Gegerfelt A, Valentin A, Alicea C, Van Rompay K, Marthas M, Montefiori D, et al. Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency vir. J Immunol. 2010;185:3348-58 pubmed publisher
- Ribeiro de Almeida C, Heath H, Krpic S, Dingjan G, van Hamburg J, Bergen I, et al. Critical role for the transcription regulator CCCTC-binding factor in the control of Th2 cytokine expression. J Immunol. 2009;182:999-1010 pubmed
- Brincks E, Katewa A, Kucaba T, Griffith T, Legge K. CD8 T cells utilize TRAIL to control influenza virus infection. J Immunol. 2008;181:4918-25 pubmed
- Jenkins M, Mintern J, La Gruta N, Kedzierska K, Doherty P, Turner S. Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8+ T cells. J Immunol. 2008;181:3818-22 pubmed
- Lages C, Suffia I, Velilla P, Huang B, Warshaw G, Hildeman D, et al. Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation. J Immunol. 2008;181:1835-48 pubmed
- Wagner C, Stegmaier S, Hänsch G. Expression of granzyme B in peripheral blood polymorphonuclear neutrophils (PMN), myeloid cell lines and in PMN derived from haemotopoietic stem cells in vitro. Mol Immunol. 2008;45:1761-6 pubmed
- Zelinskyy G, Balkow S, Schimmer S, Werner T, Simon M, Dittmer U. The level of friend retrovirus replication determines the cytolytic pathway of CD8+ T-cell-mediated pathogen control. J Virol. 2007;81:11881-90 pubmed
- Chan K, Kaur A. Flow cytometric detection of degranulation reveals phenotypic heterogeneity of degranulating CMV-specific CD8+ T lymphocytes in rhesus macaques. J Immunol Methods. 2007;325:20-34 pubmed
- Masson F, Calzascia T, Di Berardino Besson W, De Tribolet N, Dietrich P, Walker P. Brain microenvironment promotes the final functional maturation of tumor-specific effector CD8+ T cells. J Immunol. 2007;179:845-53 pubmed
- Jenkins M, Kedzierska K, Doherty P, Turner S. Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL. J Immunol. 2007;179:64-70 pubmed
- Love V, Grabie N, Duramad P, Stavrakis G, Sharpe A, Lichtman A. CTLA-4 ablation and interleukin-12 driven differentiation synergistically augment cardiac pathogenicity of cytotoxic T lymphocytes. Circ Res. 2007;101:248-57 pubmed
- Romagnani C, Juelke K, Falco M, Morandi B, D Agostino A, Costa R, et al. CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation. J Immunol. 2007;178:4947-55 pubmed
- Coquet J, Kyparissoudis K, Pellicci D, Besra G, Berzins S, Smyth M, et al. IL-21 is produced by NKT cells and modulates NKT cell activation and cytokine production. J Immunol. 2007;178:2827-34 pubmed
- Tao J, Gao Y, Li M, He W, Chen L, Harvev B, et al. JNK2 negatively regulates CD8+ T cell effector function and anti-tumor immune response. Eur J Immunol. 2007;37:818-29 pubmed
- Yang Z, Novak A, Ziesmer S, Witzig T, Ansell S. Attenuation of CD8(+) T-cell function by CD4(+)CD25(+) regulatory T cells in B-cell non-Hodgkin's lymphoma. Cancer Res. 2006;66:10145-52 pubmed
- Obar J, Fuse S, Leung E, Bellfy S, Usherwood E. Gammaherpesvirus persistence alters key CD8 T-cell memory characteristics and enhances antiviral protection. J Virol. 2006;80:8303-15 pubmed
- Macchia I, Gauduin M, Kaur A, Johnson R. Expression of CD8alpha identifies a distinct subset of effector memory CD4+ T lymphocytes. Immunology. 2006;119:232-42 pubmed
- McIlroy D, Meyer L, Dudoit Y, Samri A, Delfraissy J, Autran B, et al. Polymorphism in the proximal promoter region of the perforin gene and its impact on the course of HIV infection. Int J Immunogenet. 2006;33:73-9 pubmed
- Zhao D, Thornton A, DiPaolo R, Shevach E. Activated CD4+CD25+ T cells selectively kill B lymphocytes. Blood. 2006;107:3925-32 pubmed
- Yang T, Millar J, Groves T, Grinshtein N, Parsons R, Takenaka S, et al. The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity. J Immunol. 2006;176:200-10 pubmed
- Matsuda J, Zhang Q, Ndonye R, Richardson S, Howell A, Gapin L. T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood. 2006;107:2797-805 pubmed
- Gopcsa L, Banyai A, Jakab K, Kormos L, Tamaska J, Matolcsy A, et al. Extensive flow cytometric characterization of plasmacytoid dendritic cell leukemia cells. Eur J Haematol. 2005;75:346-51 pubmed
- Brischwein K, Schlereth B, Guller B, Steiger C, Wolf A, Lutterbuese R, et al. MT110: a novel bispecific single-chain antibody construct with high efficacy in eradicating established tumors. Mol Immunol. 2006;43:1129-43 pubmed
- Irwin S, Izzo A, Dow S, Skeiky Y, Reed S, Alderson M, et al. Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein. Infect Immun. 2005;73:5809-16 pubmed
- Bratke K, Kuepper M, Bade B, Virchow J, Luttmann W. Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood. Eur J Immunol. 2005;35:2608-16 pubmed
- Zelinskyy G, Robertson S, Schimmer S, Messer R, Hasenkrug K, Dittmer U. CD8+ T-cell dysfunction due to cytolytic granule deficiency in persistent Friend retrovirus infection. J Virol. 2005;79:10619-26 pubmed
- Klebanoff C, Gattinoni L, Torabi Parizi P, Kerstann K, Cardones A, Finkelstein S, et al. Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci U S A. 2005;102:9571-6 pubmed
- Grossman W, Radhi M, Schauer D, Gerday E, Grose C, Goldman F. Development of hemophagocytic lymphohistiocytosis in triplets infected with HHV-8. Blood. 2005;106:1203-6 pubmed
- Lang A, Nikolich Zugich J. Development and migration of protective CD8+ T cells into the nervous system following ocular herpes simplex virus-1 infection. J Immunol. 2005;174:2919-25 pubmed
- Gondek D, Lu L, Quezada S, Sakaguchi S, Noelle R. Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism. J Immunol. 2005;174:1783-6 pubmed
- Quemeneur L, Beloeil L, Michallet M, Angelov G, Tomkowiak M, Revillard J, et al. Restriction of de novo nucleotide biosynthesis interferes with clonal expansion and differentiation into effector and memory CD8 T cells. J Immunol. 2004;173:4945-52 pubmed
- Metkar S, Froelich C. Human neutrophils lack granzyme A, granzyme B, and perforin. Blood. 2004;104:905-6; author reply 907-8 pubmed
- Grossman W, Verbsky J, Tollefsen B, Kemper C, Atkinson J, Ley T. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood. 2004;104:2840-8 pubmed
- Byers A, Kemball C, Moser J, Lukacher A. Cutting edge: rapid in vivo CTL activity by polyoma virus-specific effector and memory CD8+ T cells. J Immunol. 2003;171:17-21 pubmed
- McIlroy D, Cartron P, Tuffery P, Dudoit Y, Samri A, Autran B, et al. A triple-mutated allele of granzyme B incapable of inducing apoptosis. Proc Natl Acad Sci U S A. 2003;100:2562-7 pubmed
- Kummer J, Kamp A, Tadema T, Vos W, Meijer C, Hack C. Localization and identification of granzymes A and B-expressing cells in normal human lymphoid tissue and peripheral blood. Clin Exp Immunol. 1995;100:164-72 pubmed
contribute
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
questions and comments