This is a Validated Antibody Database (VAD) review about human granulysin, based on 7 published articles (read how Labome selects the articles), using granulysin antibody in all methods. It is aimed to help Labome visitors find the most suited granulysin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
granulysin synonym: D2S69E; LAG-2; LAG2; NKG5; TLA519; granulysin; T-cell activation protein 519; T-lymphocyte activation gene 519; lymphocyte-activation gene 2; lymphokine LAG-2

BioLegend
mouse monoclonal (DH2)
  • flow cytometry; human; loading ...; fig s1d
BioLegend granulysin antibody (Biolegend, DH2) was used in flow cytometry on human samples (fig s1d). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (DH2)
  • flow cytometry; human; loading ...; fig 1j
BioLegend granulysin antibody (BioLegend, DH2) was used in flow cytometry on human samples (fig 1j). PLoS Pathog (2018) ncbi
mouse monoclonal (DH2)
  • flow cytometry; human; loading ...; fig 5b
In order to characterize gammadelta T cell subsets from healthy humans, BioLegend granulysin antibody (Biolegend, DH2) was used in flow cytometry on human samples (fig 5b). Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (DH2)
  • flow cytometry; human; loading ...; fig s1
BioLegend granulysin antibody (Biolegend, DH2) was used in flow cytometry on human samples (fig s1). J Immunol (2016) ncbi
mouse monoclonal (DH2)
  • flow cytometry; human; fig 1
In order to assess arming of MAIT cell cytolytic antimicrobial activity and induction by IL-7 and faulty in HIV-1 infection, BioLegend granulysin antibody (Biolegend, DH2) was used in flow cytometry on human samples (fig 1). PLoS Pathog (2015) ncbi
R&D Systems
goat polyclonal
  • western blot; human
R&D Systems granulysin antibody (R&D Systems, AF3138) was used in western blot on human samples . Mol Immunol (2015) ncbi
BD Biosciences
mouse monoclonal (RB1)
  • flow cytometry; human; tbl s5
In order to investigate when Vgamma9Vdelta2 T cells develop, BD Biosciences granulysin antibody (BD Bioscience, RB1) was used in flow cytometry on human samples (tbl s5). Proc Natl Acad Sci U S A (2015) ncbi
Articles Reviewed
  1. Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed publisher
  2. Ye W, Chew M, Hou J, Lai F, Leopold S, Loo H, et al. Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway. PLoS Pathog. 2018;14:e1007298 pubmed publisher
  3. Ryan P, Sumaria N, Holland C, Bradford C, Izotova N, Grandjean C, et al. Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals. Proc Natl Acad Sci U S A. 2016;113:14378-14383 pubmed
  4. Hervier B, Perez M, Allenbach Y, Devilliers H, Cohen F, Uzunhan Y, et al. Involvement of NK Cells and NKp30 Pathway in Antisynthetase Syndrome. J Immunol. 2016;197:1621-30 pubmed publisher
  5. Leeansyah E, Svärd J, Dias J, Buggert M, Nyström J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed publisher
  6. Ebsen H, Lettau M, Kabelitz D, Janssen O. Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes. Mol Immunol. 2015;65:416-28 pubmed publisher
  7. Dimova T, Brouwer M, Gosselin F, Tassignon J, Leo O, Donner C, et al. Effector Vγ9Vδ2 T cells dominate the human fetal γδ T-cell repertoire. Proc Natl Acad Sci U S A. 2015;112:E556-65 pubmed publisher