This is a Validated Antibody Database (VAD) review about human gamma-catenin, based on 29 published articles (read how Labome selects the articles), using gamma-catenin antibody in all methods. It is aimed to help Labome visitors find the most suited gamma-catenin antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
gamma-catenin synonym: CTNNG; DP3; DPIII; PDGB; PKGB; junction plakoglobin; catenin (cadherin-associated protein), gamma 80kDa; desmoplakin III; desmoplakin-3

Knockout validation
BD Biosciences
mouse monoclonal (15/?-Catenin)
  • western blot knockout validation; mouse; fig 1
In order to investigate how plakoglobin affects beta-catenin activity in the heart, BD Biosciences gamma-catenin antibody (BD, 610253) was used in western blot knockout validation on mouse samples (fig 1). Mol Cell Biol (2011) ncbi
Invitrogen
rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2b
  • western blot; mouse; loading ...; fig 3a
In order to report that SB216763 prevents myocyte injury and cardiac dysfunction in two murine models of arrhythmogenic cardiomyopathy, Invitrogen gamma-catenin antibody (Thermo Fisher, PA5-29930) was used in immunohistochemistry on mouse samples (fig 2b) and in western blot on mouse samples (fig 3a). JCI Insight (2016) ncbi
mouse monoclonal (PG-11E4)
  • immunocytochemistry; mouse; 1:500; fig 3a
  • western blot; mouse; 1:1000; fig 3b
In order to discuss the cellular origins of fibroadipocytes in arrhythmogenic cardiomyopathy, Invitrogen gamma-catenin antibody (Invitrogen, 13-8500) was used in immunocytochemistry on mouse samples at 1:500 (fig 3a) and in western blot on mouse samples at 1:1000 (fig 3b). Circ Res (2016) ncbi
mouse monoclonal (PG-11E4)
  • western blot; mouse; fig 6
In order to characterize the murine middle ear epithelial cell remodeling with NTHi by SuperSILAC quantitative proteome profiling, Invitrogen gamma-catenin antibody (Thermo Scientific, PG-11E4) was used in western blot on mouse samples (fig 6). PLoS ONE (2016) ncbi
mouse monoclonal (PG-11E4)
  • immunohistochemistry - frozen section; mouse; 1:300
In order to report that mice lacking EpCAM have intestinal barrier defects and die shortly after birth as a result of intestinal erosion, Invitrogen gamma-catenin antibody (Invitrogen, 138500) was used in immunohistochemistry - frozen section on mouse samples at 1:300. Dev Biol (2012) ncbi
mouse monoclonal (PG-11E4)
  • immunohistochemistry; human; 1:150; fig 1
In order to examine the contribution of the desmosomal compartment to gastroesophageal reflux disease, Invitrogen gamma-catenin antibody (Zymed, 138500) was used in immunohistochemistry on human samples at 1:150 (fig 1). Hum Pathol (2012) ncbi
mouse monoclonal (PG-11E4)
  • immunohistochemistry; human; 1:150; fig 1
In order to examine the role of desmosomal proteins in gastro-oesophageal reflux disease, Invitrogen gamma-catenin antibody (Zymed, PG11E4) was used in immunohistochemistry on human samples at 1:150 (fig 1). Histopathology (2012) ncbi
mouse monoclonal (PG-11E4)
  • immunoprecipitation; human; fig 1
In order to identify SOX4 binding partners, Invitrogen gamma-catenin antibody (Invitrogen, 13-8500) was used in immunoprecipitation on human samples (fig 1). BMC Cell Biol (2011) ncbi
mouse monoclonal (PG-11E4)
  • immunocytochemistry; human; fig 4
In order to identify and characterize a new type of adherens junction in human meningiomas, Invitrogen gamma-catenin antibody (Zymed, 11E4) was used in immunocytochemistry on human samples (fig 4). Cell Tissue Res (2008) ncbi
mouse monoclonal (PG-11E4)
  • western blot; human
In order to investigate whether hematopoietic cells transduce canonical Wnt signals in the absence of beta- and gamma-catenin, Invitrogen gamma-catenin antibody (Invitrogen, PG 11E4) was used in western blot on human samples . Blood (2008) ncbi
mouse monoclonal (PG-11E4)
  • immunoprecipitation; rat; tbl 1
  • western blot; rat; tbl 1
In order to determine the role of soluble guanylate cyclase in junction restructuring of the seminiferous epithelium of rat testis, Invitrogen gamma-catenin antibody (Invitrogen, 13-8500) was used in immunoprecipitation on rat samples (tbl 1) and in western blot on rat samples (tbl 1). J Cell Physiol (2006) ncbi
mouse monoclonal (PG-11E4)
  • immunocytochemistry; mouse; fig 4
  • western blot; mouse
In order to identify and characterize a novel classical cadherin adhesion system, Invitrogen gamma-catenin antibody (Zymed, PG-11E4) was used in immunocytochemistry on mouse samples (fig 4) and in western blot on mouse samples . J Cell Sci (2005) ncbi
mouse monoclonal (PG-11E4)
  • western blot; mouse
In order to examine if the epithelial-to-mesenchymal transitions and the acquisition of apoptosis resistance in cancer cells are dependent or independent events, Invitrogen gamma-catenin antibody (Zymed, PG-11E4) was used in western blot on mouse samples . Proc Natl Acad Sci U S A (2003) ncbi
mouse monoclonal (PG-11E4)
  • western blot; human; fig 3
In order to assess the localization of adherens junction components in cells expressing mutant E-cadherin derivatives, Invitrogen gamma-catenin antibody (Zymed, 13-8500) was used in western blot on human samples (fig 3). Cell Adhes Commun (2000) ncbi
Santa Cruz Biotechnology
mouse monoclonal (15F11)
  • immunocytochemistry; human; 1:100; loading ...; fig s1a
Santa Cruz Biotechnology gamma-catenin antibody (SantaCruz, sc-33634) was used in immunocytochemistry on human samples at 1:100 (fig s1a). J Exp Clin Cancer Res (2018) ncbi
mouse monoclonal (H-1)
  • western blot; human; 1:200; fig 2b
Santa Cruz Biotechnology gamma-catenin antibody (Santa Cruz, sc8415) was used in western blot on human samples at 1:200 (fig 2b). Mol Med Rep (2016) ncbi
Abcam
mouse monoclonal (15F11)
  • immunohistochemistry - frozen section; human; loading ...; fig 5b
Abcam gamma-catenin antibody (Abcam, 15F11) was used in immunohistochemistry - frozen section on human samples (fig 5b). Hum Mol Genet (2011) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; human
In order to identify the role of obscurins during breast carcinogenesis, Proteintech Group gamma-catenin antibody (Proteintech Group Inc., 11146-1-AP) was used in western blot on human samples . Oncogene (2015) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; 1:1000
In order to study the effect of epithelial cadherin expression on the induction of entosis, Cell Signaling Technology gamma-catenin antibody (Cell Signaling, 2309) was used in western blot on human samples at 1:1000. Cell Res (2014) ncbi
rabbit polyclonal
  • western blot; human; fig 5
  • western blot; fruit fly; fig 3b
In order to determine the function of greatwall-phosphorylated endosulfine as a substrate of PP2A-B55 heterotrimers and an inhibitor, Cell Signaling Technology gamma-catenin antibody (Cell Signaling Technology, 2309) was used in western blot on human samples (fig 5) and in western blot on fruit fly samples (fig 3b). elife (2014) ncbi
rabbit polyclonal
  • western blot; mouse
Cell Signaling Technology gamma-catenin antibody (Cell Signaling Technology, 2309) was used in western blot on mouse samples . BMC Gastroenterol (2013) ncbi
BD Biosciences
mouse monoclonal (15/?-Catenin)
  • immunohistochemistry - paraffin section; human; tbl 3
In order to investigate evidence for two distinct pathogenetic pathways by studing the squamous cell carcinoma of the oral cavity and cytokeratin and protein expression patterns, BD Biosciences gamma-catenin antibody (BD TL, 610253) was used in immunohistochemistry - paraffin section on human samples (tbl 3). Oncol Lett (2016) ncbi
mouse monoclonal (15/?-Catenin)
  • western blot; human
BD Biosciences gamma-catenin antibody (BD Biosciences, 610253) was used in western blot on human samples . J Biol Chem (2015) ncbi
mouse monoclonal (15/?-Catenin)
  • immunohistochemistry - frozen section; mouse; 1:200; fig 5k-m
In order to elucidate the contributions of beta-catenin during development of the peripheral nervous system, BD Biosciences gamma-catenin antibody (BD Transduction laboratories, 610253) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5k-m). BMC Biol (2015) ncbi
mouse monoclonal (15/?-Catenin)
  • immunoprecipitation; human; 1:5000
  • immunocytochemistry; human; 1:2000
  • western blot; human; 1:2000
BD Biosciences gamma-catenin antibody (BD Transduction Laboratories, 610253) was used in immunoprecipitation on human samples at 1:5000, in immunocytochemistry on human samples at 1:2000 and in western blot on human samples at 1:2000. PLoS ONE (2014) ncbi
mouse monoclonal (15/?-Catenin)
  • immunoprecipitation; common platanna; 4 ug/500 uL
In order to examine the relation between focal adhesion kinase and Xenopus mesendoderm cells, BD Biosciences gamma-catenin antibody (BD Biosciences, 610253) was used in immunoprecipitation on common platanna samples at 4 ug/500 uL. Dev Biol (2014) ncbi
mouse monoclonal (15/?-Catenin)
  • immunocytochemistry; mouse; fig s7
BD Biosciences gamma-catenin antibody (BD Biosciences, 610253) was used in immunocytochemistry on mouse samples (fig s7). PLoS ONE (2013) ncbi
mouse monoclonal (15/?-Catenin)
  • western blot knockout validation; mouse; fig 1
In order to investigate how plakoglobin affects beta-catenin activity in the heart, BD Biosciences gamma-catenin antibody (BD, 610253) was used in western blot knockout validation on mouse samples (fig 1). Mol Cell Biol (2011) ncbi
Sigma-Aldrich
mouse monoclonal (15F11)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5a
In order to study the spatio-temporal effect of p63 on palatal epithelial cell fate and the prevention of cleft palate, Sigma-Aldrich gamma-catenin antibody (Sigma, 15F11) was used in immunohistochemistry on mouse samples at 1:200 (fig 5a). PLoS Genet (2017) ncbi
mouse monoclonal (15F11)
  • immunocytochemistry; human
In order to investigate the localization of POF1B in desmosomes and its role in human intestinal and keratinocyte cell lines, Sigma-Aldrich gamma-catenin antibody (Sigma Aldrich, P8087) was used in immunocytochemistry on human samples . J Invest Dermatol (2015) ncbi
Articles Reviewed
  1. Hao X, Han F, Ma B, Zhang N, Chen H, Jiang X, et al. SOX30 is a key regulator of desmosomal gene suppressing tumor growth and metastasis in lung adenocarcinoma. J Exp Clin Cancer Res. 2018;37:111 pubmed publisher
  2. Richardson R, Mitchell K, Hammond N, Mollo M, Kouwenhoven E, Wyatt N, et al. p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017;13:e1006828 pubmed publisher
  3. Zeng F, Xie Y, Liao L, Li L, Chen B, Xie J, et al. Biological characterization of three immortalized esophageal epithelial cell lines. Mol Med Rep. 2016;14:4802-4810 pubmed publisher
  4. Frohwitter G, Buerger H, van Diest P, Korsching E, Kleinheinz J, Fillies T. Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways. Oncol Lett. 2016;12:107-113 pubmed
  5. Chelko S, Asimaki A, Andersen P, Bedja D, Amat Alarcon N, Demazumder D, et al. Central role for GSK3? in the pathogenesis of arrhythmogenic cardiomyopathy. JCI Insight. 2016;1: pubmed
  6. Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
  7. Val S, Burgett K, Brown K, Preciado D. SuperSILAC Quantitative Proteome Profiling of Murine Middle Ear Epithelial Cell Remodeling with NTHi. PLoS ONE. 2016;11:e0148612 pubmed publisher
  8. Sechler M, Borowicz S, Van Scoyk M, Avasarala S, Zerayesus S, Edwards M, et al. Novel Role for γ-Catenin in the Regulation of Cancer Cell Migration via the Induction of Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1). J Biol Chem. 2015;290:15610-20 pubmed publisher
  9. Gay M, Valenta T, Herr P, Paratore Hari L, Basler K, Sommer L. Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation. BMC Biol. 2015;13:24 pubmed publisher
  10. Olsen P, Solberg N, Lund K, Vehus T, Gelazauskaite M, Wilson S, et al. Implications of targeted genomic disruption of β-catenin in BxPC-3 pancreatic adenocarcinoma cells. PLoS ONE. 2014;9:e115496 pubmed publisher
  11. Shriver M, Stroka K, Vitolo M, Martin S, Huso D, Konstantopoulos K, et al. Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis. Oncogene. 2015;34:4248-59 pubmed publisher
  12. Sun Q, Cibas E, Huang H, Hodgson L, Overholtzer M. Induction of entosis by epithelial cadherin expression. Cell Res. 2014;24:1288-98 pubmed publisher
  13. Bjerke M, Dzamba B, Wang C, DeSimone D. FAK is required for tension-dependent organization of collective cell movements in Xenopus mesendoderm. Dev Biol. 2014;394:340-56 pubmed publisher
  14. Crespi A, Bertoni A, Ferrari I, Padovano V, Della Mina P, Berti E, et al. POF1B localizes to desmosomes and regulates cell adhesion in human intestinal and keratinocyte cell lines. J Invest Dermatol. 2015;135:192-201 pubmed publisher
  15. Williams B, Filter J, Blake Hodek K, Wadzinski B, Fuda N, Shalloway D, et al. Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers. elife. 2014;3:e01695 pubmed publisher
  16. Ito S, Satoh J, Matsubara T, Shah Y, Ahn S, Anderson C, et al. Cholestasis induces reversible accumulation of periplakin in mouse liver. BMC Gastroenterol. 2013;13:116 pubmed publisher
  17. Okumura N, Akutsu H, Sugawara T, Miura T, Takezawa Y, Hosoda A, et al. ?-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells. PLoS ONE. 2013;8:e63265 pubmed publisher
  18. Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, et al. EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol. 2012;371:136-45 pubmed publisher
  19. Wex T, Kuester D, Monkemuller K, Stahr A, Fry L, Kandulski A, et al. Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection. Hum Pathol. 2012;43:1745-54 pubmed publisher
  20. Wex T, Monkemuller K, Stahr A, Kuester D, Fry L, Völkel S, et al. Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa. Histopathology. 2012;60:405-15 pubmed publisher
  21. Lai Y, Cheng J, Cheng D, Feasel M, Beste K, Peng J, et al. SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. BMC Cell Biol. 2011;12:50 pubmed publisher
  22. Pigors M, Kiritsi D, Krümpelmann S, Wagner N, He Y, Podda M, et al. Lack of plakoglobin leads to lethal congenital epidermolysis bullosa: a novel clinico-genetic entity. Hum Mol Genet. 2011;20:1811-9 pubmed publisher
  23. Li J, Swope D, Raess N, Cheng L, Muller E, Radice G. Cardiac tissue-restricted deletion of plakoglobin results in progressive cardiomyopathy and activation of {beta}-catenin signaling. Mol Cell Biol. 2011;31:1134-44 pubmed publisher
  24. Akat K, Bleck C, Lee Y, Haselmann Weiss U, Kartenbeck J. Characterization of a novel type of adherens junction in meningiomas and the derived cell line HBL-52. Cell Tissue Res. 2008;331:401-12 pubmed
  25. Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, et al. Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin. Blood. 2008;111:142-9 pubmed
  26. Sarkar O, Xia W, Mruk D. Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions. J Cell Physiol. 2006;208:175-87 pubmed
  27. Kim Y, Sauer C, Testa K, Wahl J, Svoboda R, Johnson K, et al. Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex. J Cell Sci. 2005;118:3883-94 pubmed
  28. Grooteclaes M, Deveraux Q, Hildebrand J, Zhang Q, Goodman R, Frisch S. C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs. Proc Natl Acad Sci U S A. 2003;100:4568-73 pubmed
  29. Luber B, Candidus S, Handschuh G, Mentele E, Hutzler P, Feller S, et al. Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate. Cell Adhes Commun. 2000;7:391-408 pubmed