This is a Validated Antibody Database (VAD) review about human caveolin-2, based on 20 published articles (read how Labome selects the articles), using caveolin-2 antibody in all methods. It is aimed to help Labome visitors find the most suited caveolin-2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
caveolin-2 synonym: CAV; caveolin-2; caveolae protein, 20-kD; caveolin 2 isoform a and b

Invitrogen
mouse monoclonal (ZC013)
  • western blot; human; 1:500; fig 4
In order to study the role of miR-218 in renal cell carcinoma, Invitrogen caveolin-2 antibody (Invitrogen, P/N 41-0700) was used in western blot on human samples at 1:500 (fig 4). J Urol (2013) ncbi
Abcam
rabbit polyclonal
  • immunoprecipitation; human; fig 1
In order to show that fatty acylated cav-2 is a IR tyrosine kinase substrate during insulin signaling, Abcam caveolin-2 antibody (Abcam, ab3417) was used in immunoprecipitation on human samples (fig 1). Biochim Biophys Acta (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D4A6)
  • western blot; human; 1:100; loading ...; fig 4a
Cell Signaling Technology caveolin-2 antibody (Cell Signaling, 8522) was used in western blot on human samples at 1:100 (fig 4a). Biochem Biophys Res Commun (2018) ncbi
rabbit monoclonal (D4A6)
  • immunocytochemistry; human; loading ...; fig 5
Cell Signaling Technology caveolin-2 antibody (Cell Signaling, 8522) was used in immunocytochemistry on human samples (fig 5). PLoS ONE (2016) ncbi
rabbit monoclonal (D4A6)
  • western blot; human; 1:5000; fig 2
In order to study the clathrin- and caveolin- independent entry of BKPgammaV into primary human proximal tubule epithelial cells, Cell Signaling Technology caveolin-2 antibody (Cell signaling, 8522) was used in western blot on human samples at 1:5000 (fig 2). Virology (2016) ncbi
rabbit monoclonal (D4A6)
  • western blot; human; fig 5
Cell Signaling Technology caveolin-2 antibody (Cell Signaling, 8522) was used in western blot on human samples (fig 5). Sci Rep (2015) ncbi
rabbit monoclonal (D4A6)
  • immunohistochemistry - paraffin section; human; 1:50
  • western blot; human
In order to study the roll of cell surface heparan sulfate proteoglycans in relation to cell adhesion, Cell Signaling Technology caveolin-2 antibody (Cell Signaling, 8522) was used in immunohistochemistry - paraffin section on human samples at 1:50 and in western blot on human samples . Mol Cancer (2015) ncbi
rabbit monoclonal (D4A6)
  • western blot; human; fig s2
Cell Signaling Technology caveolin-2 antibody (Cell Signaling, 8522) was used in western blot on human samples (fig s2). Basic Res Cardiol (2014) ncbi
BD Biosciences
mouse monoclonal (65/Caveolin 2)
  • immunocytochemistry; human; loading ...; fig 7f
  • western blot; human; loading ...; fig 7h
BD Biosciences caveolin-2 antibody (BD Biosciences, 610684) was used in immunocytochemistry on human samples (fig 7f) and in western blot on human samples (fig 7h). Nat Immunol (2018) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; human; 1:1000; loading ...; fig 5f, 7d
BD Biosciences caveolin-2 antibody (BD Biosciences, 610685) was used in western blot on human samples at 1:1000 (fig 5f, 7d). J Cell Sci (2017) ncbi
mouse monoclonal (65/Caveolin 2)
  • immunoprecipitation; mouse; loading ...; fig 5c
  • immunocytochemistry; mouse; loading ...; fig 5a
  • western blot; mouse; loading ...; fig 4b
  • immunohistochemistry - paraffin section; human; loading ...; fig 3a
  • immunoprecipitation; human; fig 5c
  • immunocytochemistry; human; fig 5b
  • western blot; human; fig 4b
In order to measure the expression of caveolar protein components in liposarcoma, BD Biosciences caveolin-2 antibody (BD Transduction Laboratories, 610684) was used in immunoprecipitation on mouse samples (fig 5c), in immunocytochemistry on mouse samples (fig 5a), in western blot on mouse samples (fig 4b), in immunohistochemistry - paraffin section on human samples (fig 3a), in immunoprecipitation on human samples (fig 5c), in immunocytochemistry on human samples (fig 5b) and in western blot on human samples (fig 4b). Eur J Cell Biol (2016) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; mouse; 1:1000; fig 3
BD Biosciences caveolin-2 antibody (BD Transduction Laboratories, 610684) was used in western blot on mouse samples at 1:1000 (fig 3). PLoS ONE (2016) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; human; loading ...; fig 2a
In order to demonstrate that receptor tyrosine kinase-like orphan receptor 1 is a scaffold for cavin-1 and caveolin-1, BD Biosciences caveolin-2 antibody (BD Bioscience, 610685) was used in western blot on human samples (fig 2a). Nat Commun (2016) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; human; fig 1
BD Biosciences caveolin-2 antibody (BD Transduction Laboratories, 610685) was used in western blot on human samples (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; human
In order to investigate flotillin-1-mediated regulation of insulin-like growth factor-1 signaling, BD Biosciences caveolin-2 antibody (BD, 610685) was used in western blot on human samples . J Cell Sci (2015) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; human; fig 2
In order to show that fatty acylated cav-2 is a IR tyrosine kinase substrate during insulin signaling, BD Biosciences caveolin-2 antibody (BD, 610685) was used in western blot on human samples (fig 2). Biochim Biophys Acta (2015) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; human; loading ...; fig 7c
  • western blot; African green monkey; loading ...; fig 2
BD Biosciences caveolin-2 antibody (BD Transduction Laboratories, 610684) was used in western blot on human samples (fig 7c) and in western blot on African green monkey samples (fig 2). Traffic (2015) ncbi
mouse monoclonal (65/Caveolin 2)
  • immunohistochemistry; human; 1:200; loading ...; fig 4c
In order to discuss features of interstitial cell populations in the lamina propria of the bladder, BD Biosciences caveolin-2 antibody (BD, 65) was used in immunohistochemistry on human samples at 1:200 (fig 4c). J Urol (2014) ncbi
mouse monoclonal (65/Caveolin 2)
  • immunohistochemistry - frozen section; chicken
In order to localize and characterize cholesterol-rich membrane microdomains in the inner ear, BD Biosciences caveolin-2 antibody (BD Transduction, 610684) was used in immunohistochemistry - frozen section on chicken samples . J Proteomics (2014) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; mouse; 1:1000
BD Biosciences caveolin-2 antibody (BD Transduction laboratories, 610684) was used in western blot on mouse samples at 1:1000. PLoS ONE (2014) ncbi
mouse monoclonal (65/Caveolin 2)
  • western blot; mouse
BD Biosciences caveolin-2 antibody (BD Transduction laboratories, 610684) was used in western blot on mouse samples . Physiol Rep (2013) ncbi
Articles Reviewed
  1. Jiu Y. Vimentin intermediate filaments function as a physical barrier during intracellular trafficking of caveolin-1. Biochem Biophys Res Commun. 2018;507:161-167 pubmed publisher
  2. Borlido J, Sakuma S, Raices M, Carrette F, Tinoco R, Bradley L, et al. Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis. Nat Immunol. 2018;19:594-605 pubmed publisher
  3. Ludwig A, Nguyen T, Leong D, Ravi L, Tan B, Sandin S, et al. Caveolae provide a specialized membrane environment for respiratory syncytial virus assembly. J Cell Sci. 2017;130:1037-1050 pubmed publisher
  4. Assadi G, Vesterlund L, Bonfiglio F, Mazzurana L, Cordeddu L, Schepis D, et al. Functional Analyses of the Crohn's Disease Risk Gene LACC1. PLoS ONE. 2016;11:e0168276 pubmed publisher
  5. Codenotti S, Vezzoli M, Poliani P, Cominelli M, Bono F, Kabbout H, et al. Caveolin-1, Caveolin-2 and Cavin-1 are strong predictors of adipogenic differentiation in human tumors and cell lines of liposarcoma. Eur J Cell Biol. 2016;95:252-64 pubmed publisher
  6. Zhao L, Marciano A, Rivet C, Imperiale M. Caveolin- and clathrin-independent entry of BKPyV into primary human proximal tubule epithelial cells. Virology. 2016;492:66-72 pubmed publisher
  7. West J, Carrier E, Bloodworth N, Schroer A, Chen P, Ryzhova L, et al. Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension. PLoS ONE. 2016;11:e0148657 pubmed publisher
  8. Yamaguchi T, Lu C, Ida L, Yanagisawa K, Usukura J, Cheng J, et al. ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1. Nat Commun. 2016;7:10060 pubmed publisher
  9. Krawczyk K, Yao Mattisson I, Ekman M, Oskolkov N, Grantinge R, Kotowska D, et al. Myocardin Family Members Drive Formation of Caveolae. PLoS ONE. 2015;10:e0133931 pubmed publisher
  10. Jang D, Kwon H, Jeong K, Lee J, Pak Y. Essential role of flotillin-1 palmitoylation in the intracellular localization and signaling function of IGF-1 receptor. J Cell Sci. 2015;128:2179-90 pubmed publisher
  11. Kobayashi K, Sakurai K, Hiramatsu H, Inada K, Shiogama K, Nakamura S, et al. The miR-199a/Brm/EGR1 axis is a determinant of anchorage-independent growth in epithelial tumor cell lines. Sci Rep. 2015;5:8428 pubmed publisher
  12. Kwon H, Lee J, Jeong K, Jang D, Pak Y. Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation. Biochim Biophys Acta. 2015;1853:1022-34 pubmed publisher
  13. Han B, Tiwari A, Kenworthy A. Tagging strategies strongly affect the fate of overexpressed caveolin-1. Traffic. 2015;16:417-38 pubmed publisher
  14. Lim H, Multhaupt H, Couchman J. Cell surface heparan sulfate proteoglycans control adhesion and invasion of breast carcinoma cells. Mol Cancer. 2015;14:15 pubmed publisher
  15. Fork C, Hitzel J, Nichols B, Tikkanen R, Brandes R. Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells. Basic Res Cardiol. 2014;109:439 pubmed publisher
  16. Gevaert T, Vanstreels E, Daelemans D, Franken J, Van Der Aa F, Roskams T, et al. Identification of different phenotypes of interstitial cells in the upper and deep lamina propria of the human bladder dome. J Urol. 2014;192:1555-63 pubmed publisher
  17. Thomas P, Cheng A, Colby C, Liu L, Patel C, Josephs L, et al. Localization and proteomic characterization of cholesterol-rich membrane microdomains in the inner ear. J Proteomics. 2014;103:178-93 pubmed publisher
  18. Swärd K, Albinsson S, Rippe C. Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice. PLoS ONE. 2014;9:e92428 pubmed publisher
  19. Swärd K, Sadegh M, Mori M, Erjefalt J, Rippe C. Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF. Physiol Rep. 2013;1:e00008 pubmed publisher
  20. Yamasaki T, Seki N, Yoshino H, Itesako T, Hidaka H, Yamada Y, et al. MicroRNA-218 inhibits cell migration and invasion in renal cell carcinoma through targeting caveolin-2 involved in focal adhesion pathway. J Urol. 2013;190:1059-68 pubmed publisher